519 research outputs found

    How fast do Jupiters grow? Signatures of the snowline and growth rate in the distribution of gas giant planets

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    We present here observational evidence that the snowline plays a significant role in the formation and evolution of gas giant planets. When considering the population of observed exoplanets, we find a boundary in mass-semimajor axis space that suggests planets are preferentially found beyond the snowline prior to undergoing gap-opening inward migration and associated gas accretion. This is consistent with theoretical models suggesting that sudden changes in opacity -- as would occur at the snowline -- can influence core migration. Furthermore, population synthesis modelling suggests that this boundary implies that gas giant planets accrete ~ 70 % of the inward flowing gas, allowing ~ 30$ % through to the inner disc. This is qualitatively consistent with observations of transition discs suggesting the presence of inner holes, despite there being ongoing gas accretion.Comment: 7 pages, 6 figures, accepted for publication in Monthly Notices of the Royal Astronomical Societ

    Weak Coupling Phase Diagram of the Two Chain Hubbard Model

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    We present a general method for determining the phase diagram of systems of a finite number of one dimensional Hubbard--like systems coupled by single--particle hopping with weak interactions. The technique is illustrated by detailed calculations for the two--chain Hubbard model, providing the first controlled results for arbitrary doping and inter-chain hopping. Of nine possible states which could occur in such a spin--1/21/2 ladder, we find seven at weak coupling. We discuss the conditions under which the model can be regarded as a one--dimensional analog of a superconductor.Comment: 5 pages, self-unpacking uuencoded compressed postscript file. Also available on the WWW at http://rheims.itp.ucsb.edu/~balents/index.htm

    Characterization of THB1, a Chlamydomonas reinhardtii truncated hemoglobin: linkage to nitrogen metabolism and identification of lysine as the distal heme ligand

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    The nuclear genome of the model organism Chlamydomonas reinhardtii contains genes for a dozen hemoglobins of the truncated lineage. Of those, THB1 is known to be expressed, but the product and its function have not yet been characterized. We present mutagenesis, optical, and nuclear magnetic resonance data for the recombinant protein and show that at pH near neutral in the absence of added ligand, THB1 coordinates the heme iron with the canonical proximal histidine and a distal lysine. In the cyanomet state, THB1 is structurally similar to other known truncated hemoglobins, particularly the heme domain of Chlamydomonas eugametos LI637, a light-induced chloroplastic hemoglobin. Recombinant THB1 is capable of binding nitric oxide (NO(*)) in either the ferric or ferrous state and has efficient NO(*) dioxygenase activity. By using different C. reinhardtii strains and growth conditions, we demonstrate that the expression of THB1 is under the control of the NIT2 regulatory gene and that the hemoglobin is linked to the nitrogen assimilation pathway

    Host-Specific Response to HCV Infection in the Chimeric SCID-beige/Alb-uPA Mouse Model: Role of the Innate Antiviral Immune Response

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    The severe combined immunodeficiency disorder (SCID)-beige/albumin (Alb)-urokinase plasminogen activator (uPA) mouse containing a human-mouse chimeric liver is currently the only small animal model capable of supporting hepatitis C virus (HCV) infection. This model was utilized to characterize the host transcriptional response to HCV infection. The purpose of these studies was to investigate the genetic component of the host response to HCV infection and also to distinguish virus-induced gene expression changes from adaptive HCV-specific immune-mediated effects. Gene expression profiles from HCV-infected mice were also compared to those from HCV-infected patients. Analyses of the gene expression data demonstrate that host factors regulate the response to HCV infection, including the nature of the innate antiviral immune response. They also indicate that HCV mediates gene expression changes, including regulation of lipid metabolism genes, which have the potential to be directly cytopathic, indicating that liver pathology may not be exclusively mediated by HCV-specific adaptive immune responses. This effect appears to be inversely related to the activation of the innate antiviral immune response. In summary, the nature of the initial interferon response to HCV infection may determine the extent of viral-mediated effects on host gene expression

    Sexual selection protects against extinction

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    Reproduction through sex carries substantial costs, mainly because only half of sexual adults produce offspring. It has been theorised that these costs could be countered if sex allows sexual selection to clear the universal fitness constraint of mutation load. Under sexual selection, competition between (usually) males, and mate choice by (usually) females create important intraspecific filters for reproductive success, so that only a subset of males gains paternity. If reproductive success under sexual selection is dependent on individual condition, which depends on mutation load, then sexually selected filtering through ā€˜genic captureā€™ could offset the costs of sex because it provides genetic benefits to populations. Here, we test this theory experimentally by comparing whether populations with histories of strong versus weak sexual selection purge mutation load and resist extinction differently. After evolving replicate populations of the flour beetle Tribolium castaneum for ~7 years under conditions that differed solely in the strengths of sexual selection, we revealed mutation load using inbreeding. Lineages from populations that had previously experienced strong sexual selection were resilient to extinction and maintained fitness under inbreeding, with some families continuing to survive after 20 generations of sib Ɨ sib mating. By contrast, lineages derived from populations that experienced weak or non-existent sexual selection showed rapid fitness declines under inbreeding, and all were extinct after generation 10. Multiple mutations across the genome with individually small effects can be difficult to clear, yet sum to a significant fitness load; our findings reveal that sexual selection reduces this load, improving population viability in the face of genetic stress

    Exact SO(8) Symmetry in the Weakly-Interacting Two-Leg Ladder

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    A perturbative renormalization group analysis of interacting electrons on a two-leg ladder reveals that at half-filling any weakly repulsive system scales onto an exactly soluble Gross-Neveu model with a hidden SO(8) symmetry. The half-filled ground state is a Mott insulator with short-range d-wave pair correlations. We extract the exact energies, degeneracies, and quantum numbers of *all* the low energy excited multiplets. One energy (mass) m octets contains Cooper pair, magnon, and density-wave excitations, two more octets contain single-particle excitations, and a mass \sqrt{3}m antisymmetric tensor contains 28 "bound states". Exact single-particle and spin gaps are found for the lightly-doped (d-wave paired one-dimension Bose fluid) system. We also determine the four other robust phases occuring at half-filling for partially attractive interactions. All 5 phases have distinct SO(8) symmetries, but share S.C. Zhang's SO(5) as a common subgroup.Comment: RevTex, 35 pages with 15 figure
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