14,047 research outputs found

    The Brazilian Council for Economic and Social Development and the new developmentalist agenda in Brazil

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    No Brasil, inaugura-se um período de recuperação das capacidades de investimento do Estado e de ampliação de espaços institucionais para a participação social com a eleição do Presidente Lula em 2003. O Conselho de Desenvolvimento Econômico e Social (CDES) foi criado com o objetivo de debater as políticas desenvolvimentistas em diálogo com a sociedade civil. Por meio da análise documental, este artigo visa analisar em que medida o CDES contribuiu para a retomada da agenda desenvolvimentista nos últimos anos.En Brasil, se inauguró un período caracterizado por la capacidad de recuperación de la inversión del Estado y por la ampliación del diálogo con la sociedad civil desde la elección del Presidente Lula en el 2003. El Consejo de Desarrollo Económico y Social (CDES) se estableció con el objetivo de discutir las políticas de desarrollo en el diálogo con la sociedad civil. A partir de el análisis de documentos, este artículo tiene por objetivo analizar como la creación del CDES contribuyó a la agenda del desarrollo en los últimos años.In Brazil, a period characterized by the recovery of state investment capacity and the expansion of dialogue with civil society has begun since the election of President Lula in 2003. The Council for Economic and Social Development (CDES) was created with the objective of discussing development policies in dialogue with civil society. Based on documental analysis, this article seeks to understand how the CDES has contributed to the Brazilian development agenda in recent years.Revista do Serviço Público - RSP, v. 65, n. 2, p. 137-161Políticas Públicas e SociaisRevista do Serviço Público, ISSN eletrônico: 23578017 ISSN impresso: 0034924

    Major clinical approaches to macro and micronutrients in enteral therapy according to international guidelines and clinical studies: a systematic review

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    Introduction: In the context of Nutritional Therapy (NT), critically ill patients are associated with a state of catabolic stress and a systemic inflammatory response. Patients admitted to intensive care units (ICU) have a prevalence of malnutrition greater than 35%. The main objective of parenteral nutrition (PN) is to provide a nutrient mix closely related to requirements safely and avoid complications. However, PN poses a considerable risk of overfeeding, which can be just as harmful as underfeeding. Long-term survival data (expressed as 6-month survival) will also be considered a relevant outcome measure. Objective: It was performed a systematic review to evaluate the main clinical approaches of macro and micronutrients in enteral therapy according to international guidelines and clinical studies. Methods: The present study followed a concise systematic review model, following the systematic review rules (PRISMA). The literary search process was carried out from August to October 2022 and was developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar, using scientific articles from 2011 to 2022. The low quality of evidence was attributed to case reports, editorials, and brief communications, according to the GRADE instrument. The risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: It was found 118 studies that underwent eligibility analysis, and then 20 of the 22 total studies were selected for this systematic review. According to the GRADE instrument, most studies showed homogeneity in their results, with I2 =97.7% >50%. Standard crystalline amino acid solutions, while devoid of side effects, remain incomplete regarding their composition (eg glutamine). Lipid emulsions have come a long way and are now included in bi- and tri-compartment feeding bags, allowing for true total PN as long as daily micronutrients are prescribed. The issue of exact individual needs for energy, macro, and micronutrients has not yet been resolved. Many complications attributed to total PN are the consequence of under or overfeeding. Total PN indications have evolved towards its use alone or in combination with enteral nutrition. The start time varies by country between admission (Australia and Israel), day 4 (Swiss), and day 7 (Belgium, USA). The most important issue may be an individualized and time-dependent prescription of the feeding pathway, energy, and substrates

    Consumer behaviour in wine tourism: involvement, destination emotions and place attachment in the wine tourist behaviour during the Porto wine cellars visits context

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    Tese apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Doutor em Ciências EmpresariaisThis study aims to contribute to the conceptual development of consumer behaviour in wine tourism area by bringing new discussion and empirical evidences. For this, a literature review of the main concepts was conducted in order to develop and support a conceptual model. This model was subsequently validated and empirically tested, and a hypothetical relationship between constructs was established: involvement (personal involvement and wine product involvement), destination emotions and place attachment (place identity and place dependence). This is, so far, the first study that analyses the combined interaction of all these constructs. This research was undertaken in the framework of wine tourism, namely the measurement of the wine tourist behavior after visiting the Porto wine cellars. Methodologically, the first chapter is a qualitative exploratory study that performed a content analysis on the key constructs (involvement and emotions), allowing a better understanding of how they can be defined, and the main dimensions underlying each one of them. The second chapter consisted of a conceptual approach, which focused on the clarification of the definition of wine tourism, and the wine tourist behaviour in particular. It also explored the possible relations between constructs (involvement, destination emotions, place attachment and behavioural intentions), postulating the key preposition that stems from their interaction. In the third chapter, a quantitative research was used, using a personal intercept survey in the Porto wine cellars to validate and to give empirical evidences about the behaviour of the Porto wine cellar visitor. The multilevel analysis of the proposed structural model was made using the SmartPLS software, allowing the confirmation of all the proposed hypotheses. In the first chapter, the findings provided a theoretical support of the relevance of involvement and emotions constructs in the field of tourism. The content analysis produced insights based on concepts and definitions of these two constructs on a more holistic perspective. In the second chapter, the findings sustain the special interest in consumer behaviour in wine tourism, and it stated a set of five prepositions, where the main constructs are interlinked. In the third chapter, the empirical results indicated that wine tourists’ personal involvement and their wine product involvement have a significant influence (and a direct effect) on destination emotions and place attachment, driving their behavioural intentions. The study had direct implications (analysis and evaluation of the wine tourist travel behaviour and wine tourist profile) for the Porto wine cellars. The results led to practical implications and suggestions for wine tourism managers. Este estudo tem como propósito contribuir para o desenvolvimento conceptual do comportamento do consumidor na área do enoturismo, contribuindo com uma nova discussão e evidências empíricas. Foi realizada uma revisão da literatura sobre os principais construtos, a fim de desenvolver e apoiar um modelo conceptual. Este modelo foi posteriormente validado e testado empiricamente, e foi estabelecida uma relação hipotética entre os construtos: envolvimento (envolvimento pessoal e envolvimento com o produto vinho), as emoções do destino e apego ao lugar (identidade do lugar e dependência do lugar). Até agora, este é o primeiro estudo que analisa a interação combinada de todos estes construtos. Esta pesquisa foi realizada no âmbito do enoturismo, ou seja, a medição do comportamento do enoturista após visitar as caves do vinho do Porto. Relativamente à metodologia aplicada, o primeiro capítulo é um estudo qualitativo exploratório que resultou numa análise de conteúdo sobre os construtos chave (envolvimento e emoções), permitindo uma melhor compreensão de como eles podem ser definidos, e as principais dimensões subjacentes a cada um deles. O segundo capítulo consistiu numa abordagem conceptual que incidiu sobre a clarificação da definição de enoturismo, e o comportamento do enoturista em particular. Este capítulo também explorou as possíveis relações entre os construtos (envolvimento, emoções do destino, apego ao lugar e intenções comportamentais), que determinam a preposição chave que decorre de sua interação. No terceiro capítulo, uma pesquisa quantitativa, foi utilizado um questionário estruturado nas caves do vinho do Porto, para validar e dar evidências empíricas sobre o comportamento do visitante nas caves do vinho do Porto. Foi realizada a análise multivariada do modelo estrutural proposto, utilizando o software SmartPLS, que permitiu a confirmação de todas as hipóteses propostas. No primeiro capítulo, os resultados forneceram um suporte teórico da relevância dos construtos do envolvimento e das emoções na área do turismo. A análise de conteúdo produziu perceções com base em conceitos e definições destes dois construtos, numa perspetiva mais holística. No segundo capítulo, os resultados sustentam o especial interesse no comportamento do consumidor no enoturismo, e foi apresentado um conjunto de 5 preposições, onde os principais construtos são interligados. No terceiro capítulo, os resultados empíricos indicam que o envolvimento pessoal dos enoturistas e o seu envolvimento com o produto vinho têm uma influência significativa (e um efeito direto) sobre as emoções do destino e o apego ao lugar, impulsionando as suas intenções comportamentais. O estudo teve implicações diretas (análise e avaliação do comportamento de viagem do enoturista e perfil do enoturista) para as caves do vinho do Porto. Os resultados levaram a implicações práticas e sugestões para os gestores de enoturismo. Cette étude a pour but contribuer pour le développement conceptuel du comportement du consommateur en oenotourisme, apportant une nouvelle discussion et des évidences empiriques. Il a été faite une révision de la littérature à propos des principaux concepts, a fin de développer et soutenir un modèle conceptuel. Ce modèle a été ensuite validé et testé empiriquement, et il a été établi un rapport hypothétique entre les concepts : engagement (engagement personnel et engagement avec le produit vin), émotions du destin, attachement à l’endroit (identité et dépendance de l’endroit). Celle-ci c’est, jusqu`à présent, la première étude qui analyse l’interaction combinée des tous ces concepts. Cette recherche a été réalisée dans le cadre de l’oenotourisme, ça veut dire le mesurage du comportement de l’oenotouriste après visiter les caves du vin Porto. Méthodologiquement le premier chapitre c’est une étude qualitative exploratoire qui a réalisé une analyse du contenu sur les concepts clé (engagement et émotions), en permettant une meilleure compréhension de la façon dont ils peuvent être définis, ainsi que les dimensions principales inhérentes à chacun d’eux. Le second chapitre a consisté dans une approche conceptuelle qui portait sur la précision de la définition de l’oenotourisme, et le comportement de l’oenotouriste en particulier. Ce chapitre a aussi exploité les éventuels rapports entre les concepts (engagement, émotions du destin, attachement à l’endroit et intentions comportementales) qui postulent la préposition clé qui découle de son interaction. Dans le troisième chapitre, une recherche quantitative, il a été utilisé un questionnaire structuré dans les caves du vin Porto, a fin de valider et de donner des évidences empiriques sur le comportement du visiteur dans les caves du vin Porto. Il a été réalisé l’analyse multifactorielle du modèle structurel proposé, en utilisant le software SmartPLS qui a permis la confirmation de toutes les hypothèses proposées. Dans le premier article, les résultats ont fourni un soutien théorique de la pertinence des concepts de l’engagement et des émotions dans le domaine du tourisme. L’analyse du contenu a produit des perceptions ayant comme base des conceptions et définitions de ces deux concepts, dans un point de vue plus holistique. Dans le second article, les résultats soutiennent le spécial intérêt dans le comportement du consommateur dans l’oenotourisme, et il a été présenté un ensemble de 5 prépositions, où les principales constructions sont interconnectées. Dans le troisième article, les résultats empiriques indiquent que l’engagement avec le produit vin ont une influence significative (et un effet direct) sur les émotions du destin et l’attachement à l’endroit, en poussant ses intentions comportementales. L’étude a eu des implications directes (analyse et évaluation du comportement de voyage de l’oenotouriste et profil de l’oenotouriste) pour les caves du vin Porto. Les résultats ont amené à des implications pratiques et suggestions pour les gestionnaires de l’oenotourisme

    Major clinical outcomes of melatonin regulation in obesity: a systematic review

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    Introduction: In the scenario of non-communicable chronic diseases, obesity has briefly impacted the global population, causing serious public health problems. There are approximately 2.0 billion overweight and obese people in the world. Brazil ranks fifth in the world with approximately 18.0 million people. Research has advanced on the physiological role of melatonin (MEL) as a therapeutic agent for the treatment of obesity. Objective: It was to highlight the main clinical outcomes of melatonin regulation in obesity through a systematic review of the literature. Methods: The present study followed a concise systematic review model, following the systematic review rules (PRISMA). The literary search process was carried out from September to October 2022 and developed based on Scopus, PubMed, Science Direct, Scielo, and Google Scholar. The low quality of evidence was attributed to case reports, editorials, and brief communications, according to the GRADE instrument. The risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: It was founded 139 studies were submitted to the eligibility analysis, then, 46 of the 54 total studies were selected for this systematic review. According to the GRADE instrument, most studies showed homogeneity in their results, with I2 =98.4% >50%. Studies have shown an important role for melatonin in metabolic diseases such as obesity, type 2 diabetes mellitus, and metabolic syndrome. It is possible to define some pathological syndromes related to MEL and discuss general guidelines for clinical therapy. However, there is still no consensus on the possible role of melatonin as an adjuvant in the treatment of metabolic diseases. More studies are needed to define the possible risks and benefits of melatonin as a therapeutic agent. Furthermore, several precautions must be taken into account, such as restricting the administration of chronic melatonin to the night, carefully choosing the time of administration according to the desired effect, and adapting the dosage and formulation individually to build a melatonin blood profile that mimics the physiological and ends early in the morning

    Thermoelastic Modelling of Additive Manufacturing by Selective Laser Melting

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    Additive manufacturing represents a powerful tool for the production of lightweight and optimised aerospace components capable of enabling an overall mass reduction of the system they are embedded in and, consequently, minimising fuel consumption and pollutant emissions. In particular, combining additive methods with titanium alloys is an attractive solution for saving weight while ensuring structural integrity due to their outstanding specific mechanical properties. The problems associated with the manufacturing of titanium by traditional processes, namely the waste of raw material in relation to the material actually utilised, can be solved by the adoption of additive methods, in particular Selective Laser Melting. Active Space Technologies has been investigating additive­titanium solutions in the scope of the ADVANSS project whose aim was the research, development and manufacturing of a support structure, the Large Lens Mounting. However, the considerable heat exchanges between the substrate, the powder bed, the melt pool and the surrounding environment involved in the process are responsible for inducing large stress concentrations that may cause part failure. The main objective of this work is the development of a thermoelastic model capable of replicating the phenomena occurring during Selective Laser Melting, including material melting and subsequent cooling, with good flexibility in parameter variation. By predicting thermal stresses induced during manufacturing, it is possible to establish a set of process parameters capable of mitigating part imperfections. A series of complementary goals have been proposed as well: carrying out parametric studies to predict stresses induced by a specific set of parameters for a single layer, and later of a whole component, with n layers; building a hierarchy of parameters according to their ability to minimise stresses; and enriching Active Space Technologies expertise in additive manufacturing technologies. The prospect is that the knowledge acquired with this project contributes to the development of a similar model that would optimise the fabrication process of the Large Lens Mounting.O fabrico aditivo representa uma ferramenta poderosa na produção de componentes aeroespaciais leves e otimizados capazes de reduzir a massa do sistema onde estão inseridos e, consequentemente, o consumo de combustível e das emissões de poluentes. Em particular, a combinação de métodos aditivos e ligas de titânio é uma solução atraente para minimizar o peso ao mesmo tempo que confere integridade estrutural ao produto graças às suas excelentes propriedades mecânicas específicas. Os problemas associados ao fabrico de titânio por processos tradicionais, nomeadamente o elevado desperdício de matéria­prima em relação ao material efetivamente aproveitado, podem ser resolvidos através da adoção de métodos aditivos, em particular da Fusão Seletiva a Laser. A Active Space Technologies começou a investigar soluções de titânio em conjunto com técnicas de fabrico aditivo no âmbito do projeto ADVANSS, cujo intuito era a investigação, desenvolvimento e fabrico de uma estrutura de suporte, o Large Lens Mounting. No entanto, as consideráveis trocas de calor entre o substrato, a cama de pó, a poça de material fundido e o ambiente circundante envolvidas no processo são responsáveis por induzir grandes concentrações de tensões que podem resultar em falhas na peça. O objetivo principal deste trabalho é o desenvolvimento de um modelo termoelástico capaz de replicar os fenómenos presentes durante a Fusão Seletiva a Laser, incluindo a fusão do material e o posterior arrefecimento, com boa flexibilidade na variação dos parâmetros. Ao prever as tensões térmicas induzidas durante o processo de fabrico é possível estabelecer um conjunto de parâmetros de processamento capazes de mitigar as imperfeições das peças. Um conjunto de objetivos complementares também foi proposto: a realização de estudos paramétricos para prever tensões induzidas por um conjunto específico de parâmetros para uma única camada e, posteriormente, para um componente inteiro, com n camadas; a construção de uma hierarquia de parâmetros de acordo com sua capacidade de minimizar tensões e o enriquecimento das competências da Active Space Technologies no que diz respeito a tecnologias de manufatura aditiva. A perspectiva é que o conhecimento adquirido com este projeto contribua para o desenvolvimento de um modelo semelhante para otimizar o processo de fabricação do Large Lens Mounting

    Um estudo experimental sobre o processamento de sentenças de duas orações

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    Some temporal conjunctions can express a variety of meanings on a causal-temporal dimension. By inference, a when-clause may indicate a cause, an event prior in time, or even an event occurring simultaneously with the main clause event (Bever & Townsend, 1970). Using a self-paced reading experiment in the program Psyscope, we crossed the independent variables connective (when) and position (first position – Subordinate-Main – and second position – Main-Subordinate) to test if readers focus more on the main clause than on the subordinate clause and if readers use the order-of-mention strategy to interpret two-clause sentences conjoined with when establishing a causal-temporal relationship. Our results showed a significant effect of both structure and position factors. The online results showed that, in general, the main clause receives more reading times than the subordinate clause and that readers spent more time reading the main-subordinate sentences. The offline results indicate that the information about the first event is easier to recall if the when-clause is the first clause. Thus, the subordinate-main condition presented more accuracy rates. The order of mention strategy did not seem to be used during sentence reading processing, however, the accuracy rates were higher in conditions, in which the linguistic order mirrored the occurrence order. The main-subordinate order affected the ease of late comprehension, although it eased the reading processing.   Resumo: Algumas conjunções temporais podem expressar uma variedade de significados em uma dimensão causal-temporal. Por inferência, uma cláusula "quando" pode indicar uma causa, um evento anterior no tempo, ou mesmo um evento ocorrendo simultaneamente com o evento da cláusula principal (Bever & Townsend, 1970). Usando um experimento de leitura individualizado no programa Psyscope, cruzamos as variáveis ​​independentes conectiva (quando) e posição (primeira posição – Subordinada-Principal – e segunda posição – Principal-Subordinada) para testar se os leitores focam mais na oração principal do que na oração subordinada e se os leitores usam a estratégia de ordem de menção para interpretar frases de duas orações conjuntas ao estabelecer uma relação causal-temporal. Nossos resultados mostraram um efeito significativo dos fatores de estrutura e posição. Os resultados online mostraram que, em geral, a oração principal recebe mais tempo de leitura do que a oração subordinada e que os leitores gastam mais tempo lendo as frases principal-subordinadas. Os resultados offline indicam que as informações sobre o primeiro evento são mais fáceis de serem recuperadas se a cláusula "quando"  for a primeira cláusula. Assim, a condição subordinado-principal apresentou maiores índices de acerto. A estratégia de ordem de menção não pareceu ser utilizada durante o processamento da leitura de sentenças, porém, as taxas de acerto foram maiores em condições em que a ordem linguística espelhava a ordem de ocorrência. A ordem principal-subordinada afetou a facilidade de compreensão tardia, embora tenha facilitado o processamento da leitura.   Palavras-chave: Processamento e compreensão; conectivos temporais; quando; sintaxe experimental; frase complexa
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