An integrated optimisation platform for sustainable resource and infrastructure planning

It is crucial for sustainable planning to consider broad environmental and social dimensions and systemic implications of new infrastructure to build more resilient societies, reduce poverty, improve human well-being, mitigate climate change and address other global change processes. This article presents resilience.io, 2 a platform to evaluate new infrastructure projects by assessing their design and effectiveness in meeting growing resource demands, simulated using Agent-Based Modelling due to socio-economic population changes. We then use Mixed-Integer Linear Programming to optimise a multi-objective function to find cost-optimal solutions, inclusive of environmental metrics such as greenhouse gas emissions. The solutions in space and time provide planning guidance for conventional and novel technology selection, changes in network topology, system costs, and can incorporate any material, waste, energy, labour or emissions flow. As an application, a use case is provided for the Water, Sanitation and Hygiene (WASH) sector for a four million people city-region in Ghana

Water and energy systems in sustainable city development: a case of Sub-saharan Africa

Current urban water and energy systems are expanding while increasing attention is paid to their social, economic and environmental impacts. As a research contribution that can support real-world decision making and transitions to sustainable cities and communities, we have built a model-based and data-driven platform combining comprehensive database, agent-based simulation and resource technology network optimization for system level water and energy planning. Several use cases are demonstrated based on the Greater Accra Metropolitan Area (GAMA) city-region in Ghana, as part of the Future Cities Africa (FCA) project. The outputs depict an overall resource landscape of the studied urban area, but also provide the energy, water, and other resource balance of supply and demand from both macro and micro perspectives, which is used to propose environmental friendly and cost effective sustainable city development strategies. This work is to become a core component of the resilience.io platform as an open-source integrated systematic tool gathering social, environmental and economic data to inform urban planning, investment and policy-making for city-regions globally

O Inquérito Civil como Instrumento Legitimador da Inversão do Ônus da Prova na Ação Civil Pública Monografia

TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Jurídicas. Direito.O presente trabalho objetiva formular uma análise acerca do aproveitamento dos elementos de convicção coligidos no inquérito civil na ação civil pública, com vistas a conferir àquele instrumento maior eficácia e utilidade. Examina a ação civil pública, seu objeto e seu cabimento, bem como a origem do procedimento investigativo e suas principais características. Analisa o sistema probatório previsto no Código de Processo Civil e a sua insuficiência para a solução eficaz das demandas coletivas. Investiga as peculiaridades da prova indiciária e o seu atual aproveitamento na fase judicial. Busca demonstrar a possibilidade da inversão do ônus da prova nas ações civis públicas, qualquer que seja seu objeto. Constata a existência da verossimilhança da alegação em qualquer ação civil pública instruída com os autos do inquérito civil, o que legitima a inversão do ônus da prova

Effect of superplasticizer on the strength of fly ash based geopolymer concrete

In this research, the effect of a polycarboxylate based superplasticizer on the strength of Geopolymer Concrete (GPC) was investigated. A fixed amount of superplasticizer (1.5 % of Fly Ash weight) was utilized along with alkali activators Sodium Hydroxide (NaOH) and Sodium Silicate (Na2SiO3). The Ultrasonic Pulse Velocity Test determined the strength development of concrete. The quality of the GPC improved when a higher concentration of alkali activator was applied based on the Concrete Quality Designation. In detecting the color development of GPC, samples were put through MATLAB and specimens became lighter as time passes due to dehydration (a process where water escapes from the sample). Stress strain diagrams were generated which generally indicate that GPC specimens are ductile. The researchers were able to assess the workability of the mix designs using a rating from 1 to 5, with 1 being the least workable and 5 being the most workable

The SCottish Alcoholic Liver disease Evaluation: a population-level matched cohort study of hospital-based costs, 1991-2011

Studies assessing the costs of alcoholic liver disease are lacking. We aimed to calculate the costs of hospitalisations before and after diagnosis compared to population controls matched by age, sex and socio-economic deprivation. We aimed to use population level data to identify a cohort of individuals hospitalised for the first time with alcoholic liver disease in Scotland between 1991 and 2011.Incident cases were classified by disease severity, sex, age group, socio-economic deprivation and year of index admission. 5 matched controls for every incident case were identified from the Scottish population level primary care database. Hospital costs were calculated for both cases and controls using length of stay from morbidity records and hospital-specific daily rates by specialty. Remaining lifetime costs were estimated using parametric survival models and predicted annual costs. 35,208 incident alcoholic liver disease hospitalisations were identified. Mean annual hospital costs for cases were 2.3 times that of controls pre diagnosis (£804 higher) and 10.2 times (£12,774 higher) post diagnosis. Mean incident admission cost was £6,663. Remaining lifetime cost for a male, 50-59 years old, living in the most deprived area diagnosed with acoholic liver disease was estimated to be £65,999 higher than the matched controls (£12,474 for 7.43 years remaining life compared to £1,224 for 21.8 years). In Scotland, alcoholic liver disease diagnosis is associated with significant increases in admissions to hospital both before and after diagnosis. Our results provide robust population level estimates of costs of alcoholic liver disease for the purposes of health-care delivery, planning and future cost-effectiveness analyses

The Collagen-Binding Adhesin Is a Virulence Factor in Staphylococcus aureus Keratitis

A collagen-binding strain of Staphylococcus aureus produced suppurative inflammation in a rabbit model of soft contact lens-associated bacterial keratitis more often than its collagen-binding-negative isogenic mutant. Reintroduction of the cna gene on a multicopy plasmid into the mutant helped it regain its corneal adherence and infectivity. The topical application of a collagen-binding peptide before bacterial challenge decreased S. aureus adherence to deepithelialized corneas. These data suggest that the collagen-binding adhesin is involved in the pathogenesis of S. aureus infection of the cornea

Developing the Next Generation of Entrepreneurs: Giving Students the Opportunity to Gain Experience and Thrive

Higher Education Institutions (HEIs) have increasingly utilized experiential approaches in business education; however, some researchers have suggested that further research is required to investigate the effectiveness and student reaction to such approaches. The aim of this study is to determine the impact of an experiential learning approach on the perceived development of entrepreneurial traits and to measure the level of both student engagement and satisfaction. The approach was designed and tested during a Higher National Diploma (HND) entrepreneurship module in a British HEI. Traditional taught sessions were blended with applied activities that required students to utilize the skills they learned to complete steps of the activities, which increased in length and complexity. Results found both a high level of student satisfaction and engagement and the belief that the module’s experiential approach had, in many instances, helped to develop entrepreneurial traits. Successful practice and modifications are discussed