3,230 research outputs found
General parametric reentry study for several synchronous earth orbits
Reentry graphs for synchronous earth orbit
Independent living program evaluation for Rebuilding All Goals Efficiently
This paper evaluates the outcome of independent living (IL) services provided to clients with Spinal Cord Injuries (SCI) by a local non-profit organization, Rebuilding All Goals Efficiently (RAGE). Agency services are directed at increasing client self-sufficiency, self-advocacy, and maintenance of least restrictive living environment. Secondary data provided by RAGE for 22 SCI clients who received services in FY10 was used in the evaluation. Outcomes were measured for living arrangement at case closure, impact of services on client’s life, and cost effectiveness of services provided. Descriptive statistical analysis of the data revealed successful outcomes for all 22 SCI clients. All clients reported a decrease in functional limitation allowing them to maintain or attain the least restrictive living arrangement following provision of services. Service costs were higher for clients with 0-14 years post disability onset indicating that services were provided to the clients with the most need, either at onset of injury or to upgrade services. The report includes short and long-term recommendations to the agency for service delivery enhancement and improvement in data collection for future studies
Apparatus for testing a pressure responsive instrument Patent
Control system for pressure balance device used in calibrating pressure gage
Improving single-cell cloning workflow for gene editing in human pluripotent stem cells
The availability of human pluripotent stem cells (hPSCs) and progress in genome engineering technology have altered the way we approach scientific research and drug development screens. Unfortunately, the procedures for genome editing of hPSCs often subject cells to harsh conditions that compromise viability: a major problem that is compounded by the innate challenge of single-cell culture. Here we describe a generally applicable workflow that supports single-cell cloning and expansion of hPSCs after genome editing and single-cell sorting. Stem-Flex and RevitaCell supplement, in combination with Geltrex or Vitronectin (VN), promote reliable single-cell growth in a feeder-free and defined environment. Characterization of final genome-edited clones reveals that pluripotency and normal karyotype are retained following this single-cell culture protocol. This time-efficient and simplified culture method paves the way for high-throughput hPSC culture and will be valuable for both basic research and clinical applications. Keywords: Human pluripotent stem cells, Embryonic stem cells, Single-cell cloning, Induced pluripotent stem cells, hPSCs, hESCs, Genome engineering, CRISPR-Cas
Only God Decides\u27: Young Children\u27s Perceptions of Divorce and the Legal System
Objective: To describe research on perceptions of children aged 6 and younger from 21 families of their parents\u27 divorce, of its impact on their families, and of legal officials. Method: Semistructured play interviews were conducted during home visits as parents were conjointly interviewed as part of a larger study on divorce in legal context. Results: Children had much misinformation about divorce as an event and process. What they did know was often inappropriate, frightening, and confusing. They resented how the process \u27ruined their parents\u27 being friends any more\u27 and proposed reforms based on their wishes and observations. Conclusions: Greater awareness is needed of the child\u27s desire to be heard during the process, to feel safe and less lonely, and to stay in touch with both parents and extended families. Age-appropriate explanations of psychological and legal aspects of the divorce process are likely to support children\u27s positive adjustment and mental health
Structural assembly in space
A cost algorithm for predicting assembly costs for large space structures is given. Assembly scenarios are summarized which describe the erection, deployment, and fabrication tasks for five large space structures. The major activities that impact total costs for structure assembly from launch through deployment and assembly to scientific instrument installation and checkout are described. Individual cost elements such as assembly fixtures, handrails, or remote minipulators are also presented
NASA/DOD earth orbit shuttle traffic models based on end to end loading of payloads
An analysis of the spacecraft configurations and space missions for the Earth Orbit Shuttle traffic model based on an end-to-end loading of payloads is presented. Two possible reusable tugs are considered. The space missions are described with respect to the following: (1) number of earth orbit shuttle flights by inclination, (2) total payloads to orbit, (3) energy stages required, and (4) characteristics of reusable tug
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