A self-matched leaky-wave antenna for ultrahigh-field magnetic resonance imaging with low specific absorption rate

The technology of magnetic resonance imaging is developing towards higher magnetic fields to improve resolution and contrast. However, whole-body imaging at 7 T or even higher flux densities remains challenging due to wave interference, tissue inhomogeneities, and high RF power deposition. Nowadays, proper RF excitation of a human body in prostate and cardiac MRI is only possible to achieve by using phased arrays of antennas attached to the body (so-called surface coils). Due to safety concerns, the design of such coils aims at minimization of the local specific absorption rate (SAR), keeping the highest possible RF signal in the region of interest. Most previously demonstrated approaches were based on resonant structures such as e.g. dipoles, capacitively-loaded loops, TEM-line sections. In this study, we show that there is a better compromise between the transmit signal B1+ and the local SAR using non-resonant surface coils generating a low electric field in the proximity of their conductors. With this aim, we propose and experimentally demonstrate a leaky-wave antenna implemented as a periodically-slotted microstrip transmission line. Due to its non-resonant radiation, it induces only slightly over half the peak local SAR compared to a state-of-the-art dipole antenna but has the same transmit efficiency in prostate imaging at 7 T. Unlike other antennas for MRI, the leaky-wave antenna does not require to be tuned and matched when placed on a body, which makes it easy-to-use in prostate imaging at 7 T MRI

Autonomic neuropathy predisposes to rosiglitazone-induced vascular leakage in insulin-treated patients with type 2 diabetes: a randomised, controlled trial on thiazolidinedione-induced vascular leakage

Contains fulltext : 88447.pdf (publisher's version ) (Closed access)AIMS/HYPOTHESIS: The mechanism of fluid-related complications caused by thiazolidinedione derivatives is unclear. One potential mechanism is thiazolidinedione-induced arterial vasodilatation, which results in vascular leakage and a fall in blood pressure, normally counterbalanced by sympathetic activation and subsequent renal fluid retention. We hypothesised that thiazolidinedione-induced vascular leakage will be particularly prominent in patients with autonomic neuropathy. METHODS: We conducted a randomised, double-blind, placebo-controlled, parallel study in 40 patients with type 2 diabetes on insulin treatment recruited from a university medical centre. The randomisation was performed by a central office using a randomisation schedule. Both treatment groups, placebo (n = 21) and rosiglitazone (n = 19), were stratified for sex and level of autonomic neuropathy as assessed by Ewing score (or=2.5). We investigated the effects of 16 weeks of treatment with rosiglitazone 4 mg twice daily on vascular leakage (transcapillary escape rate of albumin, TERalb), body weight, extracellular volume and plasma volume. RESULTS: Thirty-nine patients were included in the analysis. In patients with high Ewing scores (n = 16), rosiglitazone increased TERalb significantly (DeltaTERalb: rosiglitazone +2.43 +/- 0.45%/h, placebo -0.11 +/- 0.15%/h, p = 0.002), while rosiglitazone had no effect in the patients with low Ewing scores (n = 23). Rosiglitazone-induced increases in TERalb and Ewing score at baseline were correlated (r = 0.65, p = 0.02). There was no correlation between Ewing score and rosiglitazone-induced changes in fluid variables. One subject was withdrawn from the study because of atrial fibrillation. CONCLUSIONS/INTERPRETATION: Rosiglitazone may increase vascular leakage in insulin-treated patients with type 2 diabetes with autonomic neuropathy. Autonomic neuropathy did not exaggerate rosiglitazone-induced fluid retention. Therefore, autonomic neuropathy should be considered as a risk factor for thiazolidinedione-induced oedema, not for thiazolidinedione-induced fluid retention. TRIAL REGISTRATION: ClinicalTrials.gov NCT00422955. FUNDING: GlaxoSmithKline.1 september 201

‘Better late than never’: the interplay between green technology and age for firm growth

This paper investigates the relationship between green/non-green technologies and firm growth. By combining the literature on eco-innovations, industrial organisation and entrepreneurial studies, we examine the dependence of this relationship on the pace at which firms grow and the age of the firm. From a dataset of 5498 manufacturing firms in Italy for the period of 2000–2008, longitudinal fixed effects quantile models are estimated, in which the firm’s age is set to moderate the effects of green and non-green patents on employment growth. We find that the positive effect of green technologies on growth is greater than that of non-green technologies. However, this result does not apply to struggling and rapidly growing firms. With fast-growing (above the median) firms, age moderates the growth effect of green technologies. Inconsistent with the extant literature, this moderation effect is positive: firm experience appears important for the growth benefits of green technologies, possibly relative to the complexity of their management

A framework to move forward on the path to eco-innovation in the construction industry: implications to improve firms´ sustainable orientation

This paper examines key aspects in the innovative behavior of the construction firms that determine their environmental orientation while innovating. Structural equation modeling was used and data of 222 firms retrieved from the Spanish Technological Innovation Panel (PITEC) for 2010 to analyse the drivers of environmental orientation of the construction firms during the innovation process. The results show that the environmental orientation is positively affected by the product and process orientation of construction firms during the innovation process. Furthermore, the positive relation between the importance of market information sources and environmental orientation, mediated by process and product orientation, is discussed. Finally, a model that explains these relations is proposed and validated. Results have important managerial implications for those companies worried about their eco-innovative focus as the types of actions and relations within firms most suitable for improving their eco-innovative orientation are highlighted.The authors would like to thank the Spanish Economy and Competitiveness Ministry for its support through the research project (EC02011-27369) and also the Universitat Politecnica de Valencia (SP20140647).Segarra Oña, MDV.; Peiró Signes, A.; Cervelló Royo, RE. (2015). A framework to move forward on the path to eco-innovation in the construction industry: implications to improve firms´ sustainable orientation. Science and Engineering Ethics. 21(6):1469-1484. https://doi.org/10.1007/s11948-014-9620-2S14691484216Amara, N., & Landry, R. (2005). Sources of information as determinants of novelty of innovation in manufacturing firms: evidence from the 1999 statistics Canada innovation survey. Technovation, 25(3), 245–259.Anderson, J. C., & Gerbing, D. W. (1988). Structural equation modeling in practice: A review and recommended two- step approach. Psychological Bulletin, 103(3), 411–423.Ang, G. K. I. (2004). Competing revaluing construction paradigms in practice. Rotterdam: CIB.Audet, R., & Guyonnaud, M. F. (2013). Transition in practice and action in research. A French case study in piloting eco-innovations. Innovation: The European Journal of Social Science Research, 26(4), 398–415.Bagozzi, R., & Yi, Y. (1988). On the evaluation of structural equation models. Journal of the Academy of Marketing Science, 18(1), 74–94.Barclay, D., Higgins, C., & Thompson, R. (1995). The partial least square (PLS) approach to causal modelling: Personal computer adoption and use as an illustration. Technology Studies, Special Issue on Research Methodology, 2(2), 285–309.Barrett, P. (2007). Revaluing construction: A holistic model. Building Research and Information, 35(3), 268–286.Barrett, P., & Lee, A. (2005). Revaluing construction: A CIB priority theme, Salford Centre for Research and Innovation. Salford/CIB: University of Salford, Rotterdam.Beamon, B. M. (2005). Environmental and sustainability ethics in supply chain management. Science and Engineering Ethics, 11(2), 221–234.Burciu, A., Bostan, I., Condrea, P., & Grosu, V. (2010). Financing the environmental policies in the communitarian space. Environmental Engineering and Management Journal, 9(9), 1179–1185.Carrascosa-López, C., Peiró-Signes, Á., & Segura-García-del-Río, B. (2012). Does it pay to be greener than legislation? An empirical study of spanish tile industry. Journal of Sustainable Development, 5(5), 17–26.Carter, T., & Fowler, L. (2008). Establishing green roof infrastructure through environmental policy instruments. Environmental Management, 42(1), 151–164.Cervelló-Royo, R., Garrido-Yserte, R., & Segura-García del Río, B. (2012). An urban regeneration model in heritage areas in search of sustainable urban development and internal cohesion. Journal of Cultural Heritage Management and Sustainable Development, 2(1), 44–61.Chin, W. W. (1998). The partial least squares approach to structural equation modeling. In G. A. Marcoulides (Ed.), Modern methods for business research (pp. 295–358). New Jersey: Lawrence Erlbaum Associates.Chin, W. W., Marcolin, B. L., & Newsted, P. R. (2003). A partial least squares latent variable modelling approach for measuring interaction effects: Results from a Monte Carlo simulation study and an electronic mail emotion/adoption study. Information Systems Research, 14(2), 189–217.Commission, European. (2004). Facing the challenge: The Lisbon strategy for growth and employment Brussels. Brussels: European Comission.Commission of the European Communities (2006). Action Plan for Energy Efficiency: Realising the Potential, Brussels. http://ec.europa.eu/energy/action_plan_energy_efficiency/doc/com_2006_0545_en.pdf . (Accessed 31/01/2014).Courtney, R., & Winch, G. (2002). CIB strategy for re-engineering construction. Rotterdam: CIB.Courtney, R., & Winch, G. M. (2003). Re-engineering construction: The role of research and implementation. Building Research and Information, 31(2), 172–178.Davis, M. (2001). The professional approach to engineering ethics: Five research questions. Science and Engineering Ethics, 7, 379–390.Ding, G. K. C. (2008). Sustainable construction. The role of environmental assessment tools. Journal of Environmental Management, 86(3), 451–464.Du Plessis, C., & Cole, R. J. (2011). Motivating change: Shifting the paradigm. Building Research and Information, 39(5), 436–449.Esty, D. C., & Winston, A. S. (2006). Green to gold, how smart companies use environmental strategy to innovate, create value, and build competitive advantage. Hoboken: Wiley.European Commission (2010) Europe 2020: A strategy for smart, sustainable and inclusive growth, Brussels.Falk, R., & Miller, N. (1992). A primer on soft modelling. Akron: The University of Akron Press.Fornell, C., & Larcker, D. F. (1981). Structural equation models with unobservable variables and measurement error: Algebra and statistics. Journal of Marketing Research, 18(3), 328–388.Freeman, R. E. (1994). The politics of stakeholder theory: Some future directions. Business Ethics Quarterly, 4(4), 409–422.Gázquez-Abad, J. C., Huertas-García, R., Vázquez-Gómez, M. D., & Romeo, A. C. (2014). Drivers of sustainability strategies in Spain’s wine tourism industry. Cornell Hospitality Quarterly, 1938965514549657.Gebauer, H., Gustafsson, A., & Witell, L. (2011). Competitive advantage through service differentiation by manufacturing companies. Journal of Business Research, 64(12), 1270–1280.Geisser, S. (1975). A predictive approach to the random effect model. Biometrika, 61(1), 101–107.González-Benito, O., & González-Benito, J. (2008). Implications of market orientation on the environmental transformation of industrial firms. Ecological Economics, 64(4), 752–762.Henseler, J., Ringle, C., & Sinkovics, R. (2009). The use of partial least square path modelling in international marketing. In I. Rudolf, R. Sinkovics & N. Pervez (Eds.), Advance in international marketing (Vol. 20, pp. 277–319).Hill, S., & Lorenz, D. (2011). Rethinking professionalism: Guardianship of land and resources. Building Research and Information, 39(3), 314–319.Huedo, P., & Lopez-Mesa, B. (2013). Review of tools to assist in the selection of sustainable building assemblies. Informes de la Construcción, 65(529), 77–88.IPCC. (2007a). Climate change 2007: The physical science basis. summary for policymakers: Contribution of working group i to the fourth assessment report of the intergovernmental panel on climate change. Geneva: IPCC.IPCC. (2007b). Mitigation. contribution of working group III to the fourth assessment report of the intergovernmental panel on climate change. Geneva: IPCC.Jensen, J. S., Gottlieb, S. C., & Thuese, C. L. (2011). Construction sector development: Frames and governance responses. Building Research and Information, 39(6), 665–667.Kibert, Ch J. (2007). The next generation of sustainable construction. Building Research & Information, 35(6), 595–601.Kim, Y., Brodhag, C., & Mebratu, D. (2014). Corporate social responsibility driven innovation. Innovation: The European Journal of Social Science Research, 27(2), 175–196.Kuhn, S. (2001). Commentary on: The greening of engineers: A cross-cultural experience. Science and Engineering Ethics, 7(1), 123–124.Lam, P. T., Chan, E. H., Chau, C. K., Poon, C. S., & Chun, K. P. (2011). Environmental management system vs green specifications: How do they complement each other in the construction industry? Journal of Environmental Management, 92(3), 788–795.Leimeister, S., Leimeister, J. M., & Knebel, U. (2009). A cross-national comparison of perceived strategic importance of RFID for CIOs in Germany and Italy. International Journal of Information Management, 29(1), 37–47.Leman, A., & Bordass, B. (2007). Are users more tolerant of green buildings? Building Research and Information, 35(6), 662–673.Liefferink, D., & Andersen, M. S. (1998). Strategies of the green member states in EU environmental policy-making. Journal of European Public Policy, 5(2), 254–270.Losada, B. (2013). Smart cities through the smart grid: The sustainable smart city and its energy dependence. DYNA, 88(2), 154–155.Luetzkendorf, T. (2010). Sustainable properties-dream or trend? Informes de la Construcción, 61(517), 5–15.Lützkendorf, T., & Lorenz, D. (2007). Integrating sustainability into property risk assessments for market transformation. Building Research and Information, 35(6), 644–671.Matthyssensa, P., & Vandenbempt, K. (2008). Moving from basic offerings to value-added solutions: Strategies, barriers and alignment. Industrial Marketing Management, 37(3), 316–328.McKeiver, C., & Gadenne, D. (2005). Environmental management systems in small and medium business. Small Business Journal, 23(5), 513–537.Nunnally, J. C., & Bernstein, I. H. (1995). Teoría psicométrica. México: McGraw-Hill.Parsa, H. G., Segarra-Oña, M., Jang, S. S., Chen, R., & Singh, A. J. (2014). Special issue on sustainable and eco-innovative practices in hospitality and tourism. Cornell Hospitality Quarterly, 55(1), 5–5.Pearce, D. (2006). Is the construction sector sustainable? Building Research and Information, 34(3), 201–207.Peiró-Signes, A., Miret-Pastor, L. L., Segarra-Oña, M. V., & De Miguel Molina, B. (2013). Analysing the determinants of better performance through eco management tools at the food industry: An empirical study. In P. Golinska (Ed.), Eco Production and logistics (pp. 73–90). Heidelberg: Springer.Peiró-Signes, A., Verma, R., Mondéjar-Jiménez, J., & Vargas-Vargas, M. (2014). The impact of environmental certification on hotel guest ratings. Cornell Hospitality Quarterly, 55(1), 40–51.Petruzzelli, A. M., Dangelico, R. M., Rotolo, D., & Albino, V. (2011). Organizational factors and technological features in the development of green innovations: Evidence from patent analysis. Innovation: Management, Policy and Practice, 13(3), 291–310.Porter, M. E., & Kramer, M. R. (2006). Strategy and society: The link between competitive advantage and corporate social responsibility. Harvard Business Review, 84(12), 78–92.Porter, M. E., & Van der Linde, C. (1995). Toward a new conception of the environment competitiveness relationship. Journal of Economic Perspectives, 9(4), 97–118.Rennings, K. (2002). Redefining innovation—Eco-innovation research and the contribution from ecological economics. Ecological Economics, 32(2), 319–332.Rennings, K., Ziegler, A., Ankele, K., & Hoffman, E. (2006). The influence of different characteristics of the eu environmental management and auditing scheme on technical environmental innovations and economic performance. Ecological Economics, 57(1), 45–59.Ringle, C. M., Wende, S., & Will, A. (2005). SmartPLS 2.0 M3. http:// www.smartpls.de .Sánchez-Ollero, J. L., García-Pozo, A., & Marchante-Mera, A. (2013). How does respect for the environment affect final prices in the hospitality sector? A hedonic pricing approach. Cornell Hospitality Quarterly, 55, 31–39.Schmidt, V. A., & Radaelli, C. M. (2004). Policy change and discourse in Europe: Conceptual and methodological issues. West European Politics, 27(2), 183–210.Segarra-Oña, M.D.V., M.Peiró-Signes, Á., Verma, R., & Miret-Pastor, L. (2012). Does environmental certification help the economic performance of hotels? Evidence from the spanish hotel industry. Cornell Hospitality Quarterly, 1938965512446417.Segarra-Oña, M. V., Peiró-Signes, A., Albors-Garrigós, J., & Miret-Pastor, P. (2011). Impact of innovative practices in environmentally focused firms: Moderating factors. International Journal of Environmental Research, 5(2), 425–434.Segarra-Oña, M. D. V., Peiró-Signes, A., & Mondéjar-Jiménez, J. (2013). Identifying variables affecting the proactive environmental orientation of firms: An empirical study. Polish Journal of Environmental Studies, 22(3), 873–880.Sharma, A., Thomas, D., & Konsynski, B. (2008). Strategic and institutional perspectives in the evaluation, adoption and early integration of radio frequency identification (RFID): An empirical investigation of current and potential adopters. Proceedings of the 41st Hawaii international conference on system science, Waikoloa, Big Island, Hawaii, USA (pp 407–420).Sigala, M. (2014). Customer involvement in sustainable supply chain management a research framework and implications in tourism. Cornell Hospitality Quarterly, 55(1), 76–88.Song, M., Peng, J., Liu, W., & An, Q. (2014). A PSBM model for environmental efficiency evaluation and its application. Polish Journal of Environmental Studies, 23(3), 893–900.Stern, N. (2006). The economics of climate change: The stern review. Cambridge: Cambridge University Press.Stone, M. (1974). Cross-validatory choice and assessment of statistical predictions. Journal of the Royal Statistical Society, 36, 111–147.Stone, G. W., & Wakefield, K. L. (2000). Eco-orientation: An extension of market orientation in an environmental context. Journal of Marketing Theory and Practice, 8(3), 21–31.Tenenhaus, M., Vinzi, V., Chatelin, J., & Lauro, C. (2005). PLS path modeling. Computational Statistics & Data Analysis, 48(1), 159–205.Tse, R. Y. (2001). The implementation of EMS in construction firms: Case study in Hong Kong. Journal of Environmental Assessment Policy and Management, 3(2), 177–194.Turner, R. K. (2006). Sustainability auditing and assessment challenges. Building Research and Information, 34(3), 197–200.Van Bueren, E., & De Jong, J. J. (2007). Establishing sustainability: Policy successes and failures. Building Research and Information, 35(5), 543–556.Vanasupa, L., Chen, K. C., & Slivovsky, L. (2006). Global challenges as inspiration: A classroom strategy to foster social responsibility. Science and Engineering Ethics, 12(2), 373–380.Vastag, G., Kerekes, S., & Rondinelli, D. A. (1996). Evaluation of corporate environmental management approaches: A framework and application. International Journal of Production Economics, 43(2–3), 193–211

The Phenotypic Spectrum of PNKP-Associated Disease and the Absence of Immunodeficiency and Cancer Predisposition in a Dutch Cohort

Background: We aimed to expand the number of currently known pathogenic PNKP mutations, to study the phenotypic spectrum, including radiological characteristics and genotype-phenotype correlations, and to assess whether immunodeficiency and increased cancer risk are part of the DNA repair disorder caused by mutations in the PNKP gene. Methods: We evaluated nine patients with PNKP mutations. A neurological history and examination was obtained. All patients had undergone neuroimaging and genetic testing as part of the prior diagnostic process. Laboratory measurements included potential biomarkers, and, in the context of a DNA repair disorder, we performed a detailed immunologic evaluation, including B cell repertoire analysis. Results: We identified three new mutations in the PNKP gene and confirm the phenotypic spectrum of PNKP-associated disease, ranging from microcephaly, seizures, and developmental delay to ataxia with oculomotor apraxia type 4. Irrespective of the phenotype, alpha-fetoprotein is a biochemical marker and increases with age and progression of the disease. On neuroimaging, (progressive) cerebellar atrophy was a universal feature. No clinical signs of immunodeficiency were present, and immunologic assessment was unremarkable. One patient developed cancer, but this was attributed to a concurrent von HippelLindau mutation. Conclusions: Immunodeficiency and cancer predisposition do not appear to be part of PNKP-associated disease, contrasting many other DNA repair disorders. Furthermore, our study illustrates that the previously described syndromes microcephaly, seizures, and developmental delay, and ataxia with oculomotor apraxia type 4, represent the extremes of an overlapping spectrum of disease. Cerebellar atrophy and elevated serum alpha-fetoprotein levels are early diagnostic findings across the entire phenotypical spectrum

The Relationship between Environmental Efficiency and Manufacturing Firm's Growth

This paper investigates the empirical link between emission intensity and economic growth, using a very large data set of 61,219 Italian manufacturing firms over the period 2000-2004. As a measure of lagged environmental performance (efficiency) at firm level we exploit NAMEA sector for CO2, NOx, SOx data over 1990-1999. The paper tests the extent to which (past) environmental efficiency/intensity, which is driven by structural features and firm strategic actions, including responses to policies, influences firms growth. Our results show, first, a typical trade off generally appearing for the three core environmental emissions we analyse: lower environmentally efficiency in the recent past allows higher degrees of freedom to firms and relax the constraints for growth, at least in this short/medium term scenario. Nevertheless, the size of the estimated coefficients is not large. Trade offs are significant for two emission indicators out of two, but quite negligible in terms of impacts, besides the case of CO2. For example, growth is reduced by far less than 0.1% in association to a 1% increase of environmental efficiency. In addition, non-linearity seems to characterise the economic growth-environmental performance relationship. Signals of inverted U shape appear: this may be a signal that both firm strategies and recent policy efforts are affecting the dynamic relationship between environmental efficiency and economic productivity, turning it from an usual trade off to a possible joint complementary/co-dynamics

Green process innovation: Where we are and where we are going

Environmental pollution has worsened in the past few decades, and increasing pressure is being put on firms by different regulatory bodies, customer groups, NGOs and other media outlets to adopt green process innovations (GPcIs), which include clean technologies and end-of-pipe solutions. Although considerable studies have been published on GPcI, the literature is disjointed, and as such, a comprehensive understanding of the issues, challenges and gaps is lacking. A systematic literature review (SLR) involving 80 relevant studies was conducted to extract seven themes: strategic response, organisational learning, institutional pressures, structural issues, outcomes, barriers and methodological choices. The review thus highlights the various gaps in the GPcI literature and illuminates the pathways for future research by proposing a series of potential research questions. This study is of vital importance to business strategy as it provides a comprehensive framework to help firms understand the various contours of GPcI. Likewise, policymakers can use the findings of this study to fill in the loopholes in the existing regulations that firms are exploiting to circumvent taxes and other penalties by locating their operations to emerging economies with less stringent environmental regulations.publishedVersio

The role of innovation and agglomeration for employment growth in the environmental sector

The environmental sector is supposed to yield a dual benefit: its goods and services are intended to help to tackle environmental challenges and its establishments should create new jobs. However, it is still unclear in empirical terms whether that really is the case. This paper investigates whether employment growth in 'green' establishments with 'green' products and services is higher compared to other establishments. Furthermore, the main factors determining labor demand in this field are analyzed. We use linked employment and regional data for Germany. The descriptive results show that the environmental sector is characterized by disproportionately high employment growth. The application of both a generalized linear mixed model and an instrumental variables regression reveals that especially innovation and industry agglomeration foster employment growth in establishments in the environmental sector. Establishments without green products and services show a smaller increase in employment, even if they are also innovative.Der Umweltschutzsektor verspricht einen doppelten Nutzen: seine Güter und Dienstleistungen sollen dazu beitragen, die ökologischen Herausforderungen zu bewältigen und gleichzeitig sollen dadurch neue Arbeitsplätze geschaffen werden. Ob dies wirklich der Fall ist, ist bislang jedoch nicht nachgewiesen. In unserem Artikel untersuchen wir zum einen, ob das Beschäftigungswachstum in "grünen" Betrieben tatsächlich höher ist als in anderen Betrieben. Zum anderen analysieren wir die Determinanten der Arbeitskräftenachfrage im Umweltschutzsektor. Wir verwenden verknüpfte Beschäftigten- und Regionaldaten für Deutschland. Unsere deskriptiven Ergebnisse zeigen, dass der Umweltschutzsektor durch ein überproportionales Beschäftigungswachstum gekennzeichnet ist. Unsere ökonometrische Analyse auf der Basis eines verallgemeinerten linearen gemischten Modells und einer Instrumentenschätzung zeigt, dass insbesondere Innovationen und Agglomerationseffekte das Beschäftigungswachstum in Umweltschutzbetrieben fördern. Betriebe ohne Umweltprodukte oder -dienstleistungen weisen dagegen ein geringeres Beschäftigungswachstum auf, selbst wenn es sich um innovative Betriebe handelt

Assessing the Impact of Support Policies for Energy Efficient Technology in Switzerland

This study uses data of a representative sample of Swiss firms to assess the effectiveness of policy measures directed at the diffusion of energy effcient technology (EET). Three different outcome variables (number of EET applications implemented, CO2 reduction, and EET related investment) are analysed using methods based on the estimated propensity score in an attempt to overcome the problem of non-random assignment. I conclude that, even after controlling for non-random assignment, diffusion support from the two institutions taken into consideration has indeed been beneficial in spurring adoption of energy saving technology and in reducing emissions of CO2. Additionally, an estimator for Average Treatment Effects on the Treated (ATT) that directly relies on the propensity score has been found to produce better results, in terms of efficiency, than the widely used Nearest Neighbour Matching (NNM) procedure