Hotel customer segmentation and sentiment analysis through online reviews: An analysis of selected European markets [Segmentação de clientes hoteleiros e análise de sentimento através de avaliações online: uma análise de mercados europeus selecionados]

Oliveira, A. S., Renda, A. I., Correia, M. B., & António, N. (2022). Hotel customer segmentation and sentiment analysis through online reviews: An analysis of selected European markets [Segmentação de clientes hoteleiros e análise de sentimento através de avaliações online: uma análise de mercados europeus selecionados]. Tourism & Management Studies, 18(1), 29-40. https://doi.org/10.18089/tms.2022.180----------------------------------------------This paper is financed by National Funds provided by FCTFoundation for Science and Technology through project UIDB/04470/2020This study aims to verify how distinct markets evaluate hotels in the Algarve through the analysis of online reviews, in order to identify if satisfaction and dissatisfaction attributes are similar among some of the main markets of overnight stay tourists in the region. Online reviews of hotels in the Algarve, written in English, French as well as Portuguese and posted on Tripadvisor by British, French and Portuguese residents from January 2019 to December 2019 are analysed. After the analysis of 8,596 online textual reviews, the results demonstrated that not only satisfaction and dissatisfaction rates towards hotel attributes differ according to the language, but also that customers from different countries place dissimilar emphasis on hotel attributes. Besides extending the current research on the use of online reviews, the findings of this study also assist hoteliers to identify improvement opportunities. Although many studies on marketing segmentation through data mining have been conducted, this paper analyses the customer satisfaction of relevant tourist markets and suggests up-to-date practical implications for hoteliers. --------------------------------------------------------------------------------------- Este estudo tem como objetivo verificar como mercados distintos avaliam hotéis no Algarve através da análise de comentários online, a fim de identificar se os atributos de satisfação e insatisfação são semelhantes entre alguns dos principais mercados turísticos da região. São analisadas avaliações online de hotéis no Algarve, escritas em inglês, francês e português e publicadas no Tripadvisor por residentes britânicos, franceses e portugueses de janeiro de 2019 a dezembro de 2019. Após a análise de 8.596 avaliações textuais online, os resultados demonstraram que não apenas as taxas de satisfação e insatisfação em relação aos atributos hoteleiros diferem de acordo com a língua, mas também que clientes de diferentes países colocam ênfase diferente nos atributos do hotel. Além de ampliar a pesquisa atual sobre o uso de revisões online, os resultados deste estudo também auxiliam os hoteleiros a identificar oportunidades de melhoria. Embora muitos estudos sobre segmentação de marketing por meio da mineração de dados tenham sido realizados, este artigo analisa a satisfação dos clientes dos mercados turísticos relevantes e sugere implicações práticas atualizadas para os hoteleirospublishersversionpublishe

Galactic chemical evolution

We analyze the evolution of oxygen abundance radial gradients resulting from our chemical evolution models calculated with different prescriptions for the star formation rate (SFR) and for the gas infall rate, in order to assess their respective roles in shaping gradients. We also compare with cosmological simulations and confront all with recent observational datasets, in particular with abundances inferred from planetary nebulae. We demonstrate the critical importance in isolating the specific radial range over which a gradient is measured, in order for their temporal evolution to be useful indicators of disk growth with redshift

On the origin of fluorine in the Milky Way

The main astrophysical factories of fluorine (19F) are thought to be Type II supernovae, Wolf-Rayet stars, and the asymptotic giant branch (AGB) of intermediate mass stars. We present a model for the chemical evolution of fluorine in the Milky Way using a semi-analytic multi-zone chemical evolution model. For the first time, we demonstrate quantitatively the impact of fluorine nucleosynthesis in Wolf-Rayet and AGB stars. The inclusion of these latter two fluorine production sites provides a possible solution to the long-standing discrepancy between model predictions and the fluorine abundances observed in Milky Way giants. Finally, fluorine is discussed as a possible probe of the role of supernovae and intermediate mass stars in the chemical evolution history of the globular cluster omega Centauri.Comment: 7 pages, 4 figures. MNRAS in pres

Fate of (D-Ala2)-deltorphin-I-like immunoreactive neurons in 6-hydroxydopamine lesioned rat brain

The use of a polyclonal antiserum specific to C-terminal tetrapeptide amide of (D-Ala2)deltorphin-I, a naturally occurring amphibian skin opioid peptide, has already demonstrated the presence of immunoreactive neurons in rat midbrain. Double immunostaining identified these neurons as a subpopulation of the mesencephalic dopaminergic neurons that were also tyrosine hydroxylase-immunopositive and calbindin- D28kD- negative, namely, the neurons predominantly affected in Parkinson disease. We followed the fate of these neurons after a monolateral injection of 6-hydroxy-dopamine into rat brain. Almost all the immunopositive neurons and their nigrostriatal, mesolimbic and mesocortical projections on the side ipsilateral to the lesion disappeared. Only a few scattered immunopositive neurons within the substantia nigra, pars compacta, and those of supramammillary nucleus remained unaffected. The consistent overlap of dopamine and this new molecule provides a further key to identifying the mammalian counterpart of these amphibian skin opioid peptides

Fate of (D-Ala2)-deltorphin-I-like immunoreactive neurons in 6-hydroxydopamine lesioned rat brain

The use of a polyclonal antiserum specific to C-terminal tetrapeptide amide of (D-Ala2)deltorphin-I, a naturally occurring amphibian skin opioid peptide, has already demonstrated the presence of immunoreactive neurons in rat midbrain. Double immunostaining identified these neurons as a subpopulation of the mesencephalic dopaminergic neurons that were also tyrosine hydroxylase-immunopositive and calbindin- D28kD- negative, namely, the neurons predominantly affected in Parkinson disease. We followed the fate of these neurons after a monolateral injection of 6-hydroxy-dopamine into rat brain. Almost all the immunopositive neurons and their nigrostriatal, mesolimbic and mesocortical projections on the side ipsilateral to the lesion disappeared. Only a few scattered immunopositive neurons within the substantia nigra, pars compacta, and those of supramammillary nucleus remained unaffected. The consistent overlap of dopamine and this new molecule provides a further key to identifying the mammalian counterpart of these amphibian skin opioid peptides

Galactic constraints on supernova progenitor models

Aims. To estimate the mean masses of oxygen and iron ejected per each type of supernovae (SNe) event from observations of the elemental abundance patterns in the Galactic disk and constrain the relevant SNe progenitor models. Methods. We undertake a statistical analysis of the radial abundance distributions in the Galactic disk within a theoretical framework for Galactic chemical evolution which incorporates the influence of spiral arms. This framework has been shown to recover the non-linear behaviour in radial gradients, the mean masses of oxygen and iron ejected during SNe explosions to be estimated, and constraints to be placed on SNe progenitor models. Results. (i) The mean mass of oxygen ejected per core-collapse SNe (CC SNe) event (which are concentrated within spiral arms) is similar to 0.27 M-circle dot; (ii) the mean mass of iron ejected by tardy Type Ia SNe (SNeIa, whose progenitors are older/longer-lived stars with ages greater than or similar to 100 Myr and up to several Gyr, which do not concentrate within spiral arms) is similar to 0.58 M-circle dot; (iii) the upper mass of iron ejected by prompt SNeIa (SNe whose progenitors are younger/shorter-lived stars with ages less than or similar to 100 Myr, which are concentrated within spiral arms) is <= 0.23 M-circle dot per event; (iv) the corresponding mean mass of iron produced by CC SNe is <= 0.04 M-circle dot per event; (v) short-lived SNe (core-collapse or prompt SNeIa) supply similar to 85% of the Galactic disk's iron. Conclusions. The inferred low mean mass of oxygen ejected per CC SNe event implies a low upper mass limit for the corresponding progenitors of similar to 23 M-circle dot, otherwise the Galactic disk would be overabundant in oxygen. This inference is the consequence of the non-linear dependence between the upper limit of the progenitor initial mass and the mean mass of oxygen ejected per CC SNe explosion. The low mean mass of iron ejected by prompt SNeIa, relative to the mass produced by tardy SNeIa (similar to 2.5 times lower), prejudices the idea that both sub-populations of SNeIa have the same physical nature. We suggest that, perhaps, prompt SNeIa are more akin to CC SNe, and discuss the implications of such a suggestion

Novel tricyclic pyrrolo-quinolines as pharmacological correctors of the mutant CFTR chloride channel

F508del, the most frequent mutation in cystic fibrosis (CF), impairs the stability and folding of the CFTR chloride channel, thus resulting in intracellular retention and CFTR degradation. The F508del defect can be targeted with pharmacological correctors, such as VX-809 and VX-445, that stabilize CFTR and improve its trafficking to plasma membrane. Using a functional test to evaluate a panel of chemical compounds, we have identified tricyclic pyrrolo-quinolines as novel F508del correctors with high efficacy on primary airway epithelial cells from CF patients. The most effective compound, PP028, showed synergy when combined with VX-809 and VX-661 but not with VX-445. By testing the ability of correctors to stabilize CFTR fragments of different length, we found that VX-809 is effective on the amino-terminal portion of the protein that includes the first membrane-spanning domain (amino acids 1-387). Instead, PP028 and VX-445 only show a stabilizing effect when the second membrane-spanning domain is included (amino acids 1-1181). Our results indicate that tricyclic pyrrolo-quinolines are a novel class of CFTR correctors that, similarly to VX-445, interact with CFTR at a site different from that of VX-809. Tricyclic pirrolo-quinolines may represent novel CFTR correctors suitable for combinatorial pharmacological treatments to treat the basic defect in CF

The new Checklist of the Italian Fauna: marine Mollusca.

The mollusc fauna of the Mediterranean Sea is still considered as the best-known marine mollusc fauna in the world. The previous modern checklists of marine Mollusca were produced by joint teams of amateurs and professionals. During the last years the Italian Society of Malacology (Società Italiana di Malacologia – S.I.M.) maintained an updated version of the Mediterranean checklist, that served as the backbone for the development of the new Italian checklist. According to the current version (updated on April 1st, 2021), 1,777 recognised species of marine molluscs are present in the Italian Economic Exclusive Zone, including also the Tyrrhenian coasts of Corsica and the continental shelf of the Maltese archipelago. The new checklist shows an increase of 17% of the species reported in the 1995 Checklist. This is largely (yet not solely) due to the new wave of studies based on Integrative Taxonomy approaches. A total of 135 species (7.6%) are strictly endemic to the Italian waters; 44 species (2.5%) are alien and correspond to the 28% of the Mediterranean alien marine molluscs. All eight extant molluscan classes are represented. The families represented in the Italian fauna are 307, an increase of 14.6% from the first checklist, partly due to new records and partly to new phylogenetic systematics. Compared with the whole Mediterranean malacofauna, the Italian component represents 71% in species and 61% in families, which makes it a very remarkable part of the Mediterranean fauna

Contrast Agents during Pregnancy: Pros and Cons When Really Needed

Many clinical conditions require radiological diagnostic exams based on the emission of different kinds of energy and the use of contrast agents, such as computerized tomography (CT), positron emission tomography (PET), magnetic resonance (MR), ultrasound (US), and X-ray imaging. Pregnant patients who should be submitted for diagnostic examinations with contrast agents represent a group of patients with whom it is necessary to consider both maternal and fetal effects. Radiological examinations use different types of contrast media, the most used and studied are represented by iodinate contrast agents, gadolinium, fluorodeoxyglucose, gastrographin, bariumsulfate, and nanobubbles used in contrast-enhanced ultrasound (CEUS). The present paper reports the available data about each contrast agent and its effect related to the mother and fetus. This review aims to clarify the clinical practices to follow in cases where a radiodiagnostic examination with a contrast medium is indicated to be performed on a pregnant patient