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59 research outputs found

Erratum to: CXCL14 and MCP1 are potent trophic factors associated with cell migration and angiogenesis leading to higher regenerative potential of dental pulp side population cells

Author: Masashi Murakami
Misako Nakashima
Osamu Fukuta
Rei Kawamura
Ryo Ishizaka
Yuki Hayashi
Publication venue: Springer Nature
Publication date: 01/01/2016
Field of study

Gastric Ulcer Associated with Cytomegalovirus in an Immunocompetent Patient: Method for Diagnosis

Author: Akira Kawamura
Allen JI
Chikara Ebisutani
Cohen JI
de Castro ML
Himoto T
Keiko Mimura
Masamichi Nasu
Norihito Shibata
Péter A
Rei Ueno
Yoshikazu Kinoshita
Publication venue: S. Karger AG
Publication date: 01/01/2012
Field of study

Cytomegalovirus (CMV)-associated gastric ulcers can be found not only in immunocompromised hosts but also in normal individuals. The accurate endoscopic diagnosis of CMV ulcers is not easy because of the absence of characteristic morphological features. We present a case of CMV-associated gastric ulcer in an immunocompetent patient. He was a 33-year-old male with epigastralgia. Upper gastrointestinal endoscopy showed multiple erupted papules and a large irregularly shaped shallow ulcer. We did not find intracellular inclusion bodies characteristic of CMV in hematoxylin-eosin-stained gastric biopsy specimens, while CMV antigens corresponding to intracellular inclusion bodies were confirmed using an immunoperoxidase method with the monoclonal CMV antibody. If CMV ulcers are suspected, it is important to examine for inclusion bodies using not only hematoxylin-eosin staining, but also CMV immunohistochemistry for a sensitive diagnosis

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PubMed Central

Factors associated with good self-rated health of non-disabled elderly living alone in Japan: a cross-sectional study

Author: AT Beekman
BM Van Gelder
BW Penninx
EL Idler
H Imuta
H Yokoyama
J Damian
J Liang
JJ Wang
JJ Wang
JK Djernes
K Ikebe
K Kawamura
K Toba
K Yamashita
Kan Usuda
KB DeSalvo
Koichi Kono
KS You
M Azegami
M Iwasaki
M Kuzuya
M Watanabe
Masahisa Saito
Misuzu Watanabe
MT Hoyl
MV Zunzunegui
MV Zunzunegui
N Spiers
N Wang
P Rinaldi
PJ Lorraine
Rei Kono
S Heistaro
S Koukouli
SM Alibhai
SV Subramanian
T Kawada
Takahiro Shibutani
Wei Sun
Y Fujiwara
Y Takata
Yoshimi Tanimoto
ZN Kabir
Publication venue: BioMed Central
Publication date: 01/01/2007
Field of study

Abstract Background Self-rated health (SRH) is reported as a reliable predictor of disability and mortality in the aged population and has been studied worldwide to enhance the quality of life of the elderly. Nowadays, the elderly living alone, a particular population at great risk of suffering physical and mental health problems, is increasing rapidly in Japan and could potentially make up the majority of the aged population. However, few data are available pertaining to SRH of this population. Given the fact that sufficient healthcare is provided to the disabled elderly whereas there is little support for non-disabled elderly, we designed this population-based survey to investigate SRH of non-disabled elderly living alone and to identify the factors associated with good SRH with the purpose of aiding health promotion for the elderly. Methods A cross-sectional study was conducted in a metropolitan suburb in Japan. Questionnaires pertaining to SRH and physical conditions, lifestyle factors, psychological status, and social activities, were distributed in October 2005 to individuals aged ≥ 65 years and living alone. Response rate was 75.1%. Among these respondents, a total of 600 male and 2587 female respondents were identified as non-disabled elderly living alone and became our subjects. Multivariate logistic regression was used to identify the factors associated with good SRH and sex-specific effect was tested by stepwise logistic regression. Results Good SRH was reported by 69.8% of men and 73.8% of women. Multivariate logistic regression analysis showed that good SRH correlated with, in odds ratio sequence, "can go out alone to distant places", no depression, no weight loss, absence of self-rated chronic disease, good chewing ability, and good visual ability in men; whereas with "can go out alone to distant places", absence of self-rated chronic disease, no weight loss, no depression, no risk of falling, independent IADL, good chewing ability, good visual ability, and social integration (attend) in women. Conclusion For the non-disabled elderly living alone, sex-appropriate support should be considered by health promotion systems from the view point of SRH. Overall, the ability to go out alone to distant places is crucial to SRH of both men and women.</p

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Springer - Publisher Connector

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PubMed Central

Improved development of mouse and human embryos using a tilting embryo culture system

Author: Cabrera
Chisato Takiue
Cohen
Contramaestre
Cui
Eddy
Fox
Gardner
Halbert
Hardy
Kawamura
Keiji Naruse
Koji Matsuura
Lyons
Mami Takenami
Melin
Mottla
Nagai
Nanako Yoshioka
Nobuyoshi Hayashi
Rei Hirata
Staigmiller
Suarez
Tetsunori Mukaida
Toshihiro Habara
Wang
Xie
Xie
Yoko Aoi
Yuka Kuroda
Zervomanolakis
Publication venue: 'Elsevier BV'
Publication date: 01/03/2010
Field of study

Mammalian embryos experience not only hormonal but also mechanical stimuli, such as shear stress, compression and friction force in the Fallopian tube before nidation. In order to apply mechanical stimuli to embryos in a conventional IVF culture system, the tilting embryo culture system (TECS) was developed. The observed embryo images from the TECS suggest that the velocities and shear stresses of TECS embryos are similar to those experienced in the oviduct. Use of TECS enhanced the development rate to the blastocyst stage and significantly increased the cell number of mouse blastocysts (P < 0.05). Although not statistically significant, human thawed embryos showed slight improvement in development to the blastocyst stage following culture in TECS compared with static controls. Rates of blastocyst formation following culture in TECS were significantly improved in low-quality embryos and those embryos cultured under suboptimal conditions (P < 0.05). The TECS is proposed as a promising approach to improve embryo development and blastocyst formation by exposing embryos to mechanical stimuli similar to those in the Fallopian tube

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Okayama University Scientific Achievement Repository

Prospects for observing and localizing gravitational-wave transients with Advanced LIGO, Advanced Virgo and KAGRA

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and Abbott B. P.
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and Aiello O. D.
and Ain L.
and Ajith A.
and Akutsu P.
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Calderon and Callister J.
Casanueva and Casentini J.
Cerboni and Cerretani L.
Da Silva and Dattilo C. F.
Dovale and Downes M.
Fernandez and Ferrante A.
Gonzalez and Gopakumar J. M.
Marchesoni F.
R. and E. A.
R. J
Travasso F.
Publication venue: 'Springer Science and Business Media LLC'
Publication date: 01/01/2018
Field of study

We present possible observing scenarios for the Advanced LIGO, Advanced Virgo and KAGRA gravitational-wave detectors over the next decade, with the intention of providing information to the astronomy community to facilitate planning for multi-messenger astronomy with gravitational waves. We estimate the sensitivity of the network to transient gravitational-wave signals, and study the capability of the network to determine the sky location of the source. We report our findings for gravitational-wave transients, with particular focus on gravitational-wave signals from the inspiral of binary neutron star systems, which are the most promising targets for multi-messenger astronomy. The ability to localize the sources of the detected signals depends on the geographical distribution of the detectors and their relative sensitivity, and 90% credible regions can be as large as thousands of square degrees when only two sensitive detectors are operational. Determining the sky position of a significant fraction of detected signals to areas of 5– 20 deg2 requires at least three detectors of sensitivity within a factor of ∼2 of each other and with a broad frequency bandwidth. When all detectors, including KAGRA and the third LIGO detector in India, reach design sensitivity, a significant fraction of gravitational-wave signals will be localized to a few square degrees by gravitational-wave observations alone

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