1,030 research outputs found
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Simulating the sensitivity of evapotranspiration and streamflow to large-scale groundwater depletion
Groundwater pumping has caused marked aquifer storage declines over the past century. In addition to threatening the viability of groundwater-dependent economic activities, storage losses reshape the hydrologic landscape, shifting groundwater surface water exchanges and surface water availability. A more comprehensive understanding of modern groundwater-depleted systems is needed as we strive for improved simulations and more efficient water resources management. Here, we begin to address this gap by evaluating the impact of 100 years of groundwater declines across the continental United States on simulated watershed behavior. Subsurface storage losses reverberate throughout hydrologic systems, decreasing streamflow and evapotranspiration. Evapotranspiration declines are focused in water-limited periods and shallow groundwater regions. Streamflow losses are widespread and intensify along drainage networks, often occurring far from the point of groundwater abstraction. Our integrated approach illustrates the sensitivity of land surface simulations to groundwater storage levels and a path toward evaluating these connections in large-scale models.U.S. Department of Energy Office of Science, Offices of Advanced Scientific Computing Research and Biological and Environmental Sciences IDEAS project; Sustainable Systems Scientific Focus Area [DE-AC02-05CH11231]Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
The Budyko shape parameter as a descriptive index for streamflow loss
Increases in evapotranspiration (ET) from global warming are decreasing streamflow in headwater basins worldwide. However, these streamflow losses do not occur uniformly due to complex topography. To better understand the heterogeneity of streamflow loss, we use the Budyko shape parameter (ω) as a diagnostic tool. We fit ω to 37-year of hydrologic simulation output in the Upper Colorado River Basin (UCRB), an important headwater basin in the US. We split the UCRB into two categories: peak watersheds with high elevation and steep slopes, and valley watersheds with lower elevation and gradual slopes. Our results demonstrate a relationship between streamflow loss and ω. The valley watersheds with greater streamflow loss have ω higher than 3.1, while the peak watersheds with less streamflow loss have an average ω of 1.3. This work highlights the use of ω as an indicator of streamflow loss and could be generalized to other headwater basin systems
Student perceptions of a healthy university
As complex environments within which individuals and populations operate, universities present important contexts for understanding and addressing health issues. The healthy university is an example of the settings approach, which adopts a whole system perspective, aiming to make places within which people, learn, live, work and play supportive to health and wellbeing. The UK Healthy Universities Network has formulated an online toolkit, which includes a self-review tool, intended to enable universities to assess what actions they need to take to develop as a healthy university. This paper presents findings from consultative research undertaken with students from universities in England, Scotland and Wales, which explored what they believe represents a healthy university.
Methods
Student surveys and focus groups were used to collect data across eleven universities in England, Scotland and Wales. A priori themes were used to develop our own model for a healthy university, and for the thematic coding phase of analysis.
Findings
A healthy university would promote student health and wellbeing in every aspect of its business from its facilities and environment through to its curriculum. Access to reasonably priced healthy food and exercise facilities were key features of a healthy university for students in this study. The Self Review Tool has provided a crucial start for universities undertaking the journey towards becoming a healthy university. In looking to the future both universities and the UK Healthy Universities Network will now need to look at what students want from their whole university experience, and consider how the Self Review Tool can help universities embrace a more explicit conceptual framework.
Conclusion
The concept of a healthy university that can tailor its facilities and supportive environments to the needs of its students will go some way to developing students who are active global citizens and who are more likely to value and prioritise health and wellbeing, in the short and long term through to their adult lives
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The imprint of climate and geology on the residence times of groundwater
Surface and subsurface flow dynamics govern residence time or water age until discharge, which is a key metric of storage and water availability for human use and ecosystem function. Although observations in small catchments have shown a fractal distribution of ages, residence times are difficult to directly quantify or measure in large basins. Here we use a simulation of major watersheds across North America to compute distributions of residence times. This simulation results in peak ages from 1.5 to 10.5 years, in agreement with isotopic observations from bomb-derived radioisotopes, and a wide range of residence times—from 0.1 to 10,000 years. This simulation suggests that peak residence times are controlled by the mean hydraulic conductivity, a function of the prevailing geology. The shape of the residence time distribution is dependent on aridity, which in turn determines water table depth and the frequency of shorter flow paths. These model results underscore the need for additional studies to characterize water ages in larger systems
Greenhushing: the deliberate under communicating of sustainability practices by tourism businesses
Greenhushing selectively communicates fewer pro-sustainability actions by businesses than are practiced; based on a perception of customers’ rights to consumerism. We first studied the gap between the communication of sustainability practices in the audits and websites of 31 small rural tourism businesses in the Peak District National Park (UK). The analysis showed that businesses only communicate 30% of all the sustainability actions practiced. Their websites emphasised customer benefits, using explicit, affective, experiential and active language that legitimises the customers’ hedonistic use of the landscape, while downplaying complex issues and normalising sustainability to reduce customer guilt. Just one website mentioned climate change. We found that greenhushing results from a low moral intensity, masking potentially negative consequences of perceived lower competence, whilst protecting business from more cynical consumers who may interpret their statements as hypocritical. Subsequent textual analysis and interviews were used to understand how communication constitutes these organisations. We propose that greenhushing reshapes and constitutes tourism businesses through their communications. Moreover, greenhushing is a form of public moralisation that adopts communication practices similar to greenwashing, reflecting the social norms expected from a business; however, in this case, located in a moral muteness, rather than moral hypocrisy, that businesses accept but resent
Ground water and climate change
As the world’s largest distributed store of fresh water, ground water plays a central part in sustaining ecosystems and enabling human adaptation to climate variability and change. The strategic importance of ground water for global water and food security will probably intensify under climate change as more frequent and intense climate extremes (droughts and floods) increase variability in precipitation, soil moisture and surface water. Here we critically review recent research assessing the impacts of climate on ground water through natural and human-induced processes as well as through groundwater-driven feedbacks on the climate system. Furthermore, we examine the possible opportunities and challenges of using and sustaining groundwater resources in climate adaptation strategies, and highlight the lack of groundwater observations, which, at present, limits our understanding of the dynamic relationship between ground water and climate
PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer
Here we describe the expression and function of a HIF-1-regulated protein pyruvate dehydrogenase kinase-1 (PDK-1) in head and neck squamous cancer (HNSCC). Using RNAi to downregulate hypoxia-inducible PDK-1, we found that lactate and pyruvate excretion after 16–48 h of hypoxia was suppressed to normoxic levels. This indicates that PDK-1 plays an important role in maintaining glycolysis. Knockdown had no effect on proliferation or survival under hypoxia. The immunohistochemical expression of PDK-1 was assessed in 140 cases of HNSCC. PDK-1 expression was not expressed in normal tissues but was upregulated in HNSCC and found to be predominantly cytoplasmic with occasional strong focal nuclear expression. It was strongly related to poor outcome (P=0.005 split by median). These results indicate that HIF regulation of PDK-1 has a key role in maintaining lactate production in human cancer and that the investigation of PDK-1 inhibitors should be investigated for antitumour effects
Single-cell resolution imaging of retinal ganglion cell apoptosis in vivo using a cell-penetrating caspase-activatable peptide probe
Peptide probes for imaging retinal ganglion cell (RGC) apoptosis consist of a cell-penetrating peptide targeting moiety and a fluorophore-quencher pair flanking an effector caspase consensus sequence. Using ex vivo fluorescence imaging, we previously validated the capacity of these probes to identify apoptotic RGCs in cell culture and in an in vivo rat model of N-methyl- D-aspartate (NMDA)-induced neurotoxicity. Herein, using TcapQ488, a new probe designed and synthesized for compatibility with clinically-relevant imaging instruments, and real time imaging of a live rat RGC degeneration model, we fully characterized time- and dose-dependent probe activation, signal-to-noise ratios, and probe safety profiles in vivo. Adult rats received intravitreal injections of four NMDA concentrations followed by varying TcapQ488 doses. Fluorescence fundus imaging was performed sequentially in vivo using a confocal scanning laser ophthalmoscope and individual RGCs displaying activated probe were counted and analyzed. Rats also underwent electroretinography following intravitreal injection of probe. In vivo fluorescence fundus imaging revealed distinct single-cell probe activation as an indicator of RGC apoptosis induced by intravitreal NMDA injection that corresponded to the identical cells observed in retinal flat mounts of the same eye. Peak activation of probe in vivo was detected 12 hours post probe injection. Detectable fluorescent RGCs increased with increasing NMDA concentration; sensitivity of detection generally increased with increasing TcapQ488 dose until saturating at 0.387 nmol. Electroretinography following intravitreal injections of TcapQ488 showed no significant difference compared with control injections. We optimized the signal-to-noise ratio of a caspase-activatable cell penetrating peptide probe for quantitative non-invasive detection of RGC apoptosis in vivo. Full characterization of probe performance in this setting creates an important in vivo imaging standard for functional evaluation of future probe analogues and provides a basis for extending this strategy into glaucoma-specific animal models
The integrated hydrologic model intercomparison project, IH-MIP2: A second set of benchmark results to diagnose integrated hydrology and feedbacks
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