Comparative Analysis of common Edge Detection Algorithms using Pre-processing Technique

Edge detection is the process of segmenting an image by detecting discontinuities in brightness. So far, several standard segmentation methods have been widely used for edge detection. However, due to inherent quality of images, these methods prove ineffective if they are applied without any preprocessing. In this paper, an image preprocessing approach has been adopted in order to get certain parameters that are useful to perform better edge detection with the standard edge detection methods. The proposed preprocessing approach involves median filtering to reduce the noise in image and then Edge Detection technique is carried out. And atlast Standard edge detection methods can be applied to the resultant preprocessing image and its Simulation results are show that our preprocessed approach when used with a standard edge detection method enhances its performance

Herbal immunomodulators as add on treatment in asymptomatic and mildly symptomatic COVID-19 confirmed cases: findings from a prospective single centre clinical trial

Background: The aim of the present study was to evaluate safety and efficacy of Sri Sri TattvaTM immunity products, a combination of single herb and poly herb formulations in COVID-19 patients by assessing their clinical features and immune markers. The products when administered orally for a period of 14 days in COVID-19 patients demonstrated significant improvement in clinical symptoms.Methods: Patients with fever, cough, sore throat started responding to the treatment from day 3 and most of the patients were clinically free of symptoms by day 7. Early recovery from signs and symptoms was observed in most of the patients. Sri Sri TattvaTM immunity products has also demonstrated an excellent clinical improvement and immune markers including tumor necrosis factor (TNF-alfa), interleukin (IL-6), interferon (IFN-beta), D-dimer, ferritin, lactate dehydrogenease (LDH) and C-reactive protein (CRP) in COVID-19 patients.Results: The final results of this study showed that Sri Sri TattvaTM immunity products reduced the time to clinical cure and number of days in achieving negative real time polymerase chain reaction (RT-PCR) by early viral clearance when given along with standard of care thus reduced the duration of hospitalization.Conclusions: In the present study, 82% of COVID-19 patients cleared the virus within 10-14 days of study period reducing the duration of hospitalization. None of the patients progressed to severe COVID-19 and succumbed to the disease. This clearly indicates that Sri Sri TattvaTM immunity products when administered orally along with standard of care has definitive role in the management of COVID-19 patients

Design & Manufacturing of Implant for reconstructive surgery: A Case Study

Additive Manufacturing (AM), also known as 3D printing is an emerging technology in oral & maxillofacial surgery with respect to reconstructive bone surgery. Such treatment protocols often require customized implants to fulfill the functional and aesthetic requirements. Currently, such customized implants are being manufactured using AM technology. This paper describes a mandible defect of oral & maxillofacial surgery. The fracture and defect of the mandible inferior border is one of the serious complications during alignment and fixing of the implant. Reconstruction of such defects is daunting tasks. The case report describes a method based on Computer Aided Design (CAD) and AM for individual design, fabrication and implantation of a mandible inferior border. A 40-year old male meet an accident with rash drive. The patient specific customized implant is designed with patient Computed Tomography (CT) data. The CT images in Digital Imaging and Communication in Medicine (DICOM) file format is used to develop a 3D CAD model of customized implant. The implant is designed to maintain the symmetry of mandible from right to left. The designed implant model is manufactured by Fused Deposition Modelling (FDM) techniques with a biocompatible material. The patient mandible prototype model was manufactured by AM process, which is helpful for pre-planning of surgical procedures. For these pre-planning surgical procedures, a perfect fit obtained during surgery. The patient ultimately regained reasonable mandible contour and appearance of the face.

STANDARDIZATION IN VITRO ANTIOXIDANT ACTIVITY AND BRINE SHRIMP LETHALITY OF A POLYHERBAL FORMULATION

Shakti drops an Ayurvedic polyherbal formulation is an effective medicine for immuno modulatory activity. The formulation was prepared in the laboratory with authenticated organic plant drugs. The standardization procedure was conducted on the basis of physicochemical parameters and antimicrobial studies as directed by Ayurvedic formulary of India. Antioxidant activity is further performed based on its prescribed dose in three In-vitro antioxidant models. Physical characters remained unaltered throughout study, In antimicrobial activity total aerobic count was found to be 18×101 CFU/mL and total fungal count was found to be <10 CFU/mL. It is devoid of all tested microorganism i.e. Staphylococcus aureus, Salmonella typhi, Pseudomonas aeruginosa, Escherichia coli tested. In antioxidant activity the results of the study suggest that the Shiakti drops has potent antioxidant and free radical scavenging activity justifying its use in Rasayana

Climate change effects on Chickpea yield and its variability in Andhra Pradesh, India

Farmers usually do not know the precise output that is affected by climatic factors such as temperature and rainfall and are characterized by inter-annual variability, part of which is caused by global climate change. No study covers the influences of climate factors on yield and yield risk in the context of chickpea farming in Andhra Pradesh, India. In this context, this study aimed to investigate the trends in climate change variables during Rabi season (October to January, 1996-2020) and evaluated their variability on chickpea yields across different agro-climatic zones in Andhra Pradesh by employing Just and Pope production function. Four non-parametric methods-Alexandersson’s Standard Normal Homogeneity Test, Buishand’s Range Test, Pettitt’s Test and Von Neumann’s Ratio Test are applied to detect homogeneity in the data. Mann–Kendall (MK) test and Sen’s slope (SS) method were employed to analyze monthly rainfall trends and minimum and maximum temperature trends. Results of Just and Pope (panel data) quadratic and Cobb-Douglas methods revealed that monthly minimum temperature positively influenced the mean yield of chickpea (0.22% and 0.16%, respectively). However, rainfall (-0.41% and -0.31%) and maximum temperature (-0.08% and -0.04%) negatively influenced the mean yield of chickpea under quadratic and Cobb-Douglas models, respectively. Accordingly, rainfall (0.08% and 0.06%) and maximum temperature (0.83% and 0.72%) positively influenced the yield variability and minimum temperature (-0.77% and -0.67%) reduced yield variability of chickpea under quadratic and Cobb-Douglas models respectively. In view of these findings, it is imperative to advocate the farmers about the importance of cultivating drought-tolerant chickpea varieties, drought-proofing and mitigation strategies, micro-irrigation practices and improving their access to agro-meteorological information towards sustainable chickpea cultivation in Andhra Pradesh

STUDIES ON GROUNDWATER QUALITY IN ANANTAPUR DISTRICT

ABSTRACT: Ground water is the main principal source for drinking water and other activities in Andhra Pradesh. It is the basic duty of every individual to conserve water resources. The present study attempts to bring an acute awareness among the people about the quality of ground water by taking water samples from 33 specific locations in Anantapur district to characterize the physicochemical parameters of Ground water. To assess the quality of groundwater, each parameter was compared with the standard desirable limit of that parameter in drinking water as prescribed by different agencies. This paper is a new study on water quality parameters in analyzing Anantapur district drinking water

2-(2,6-Dimethoxy­phen­yl)-5-hydr­oxy-7-meth­oxy-4H-1-benzopyran-4-one

In the title compound, C18H16O6, the dimethoxy­phenyl ring is rotated by 61.8 (1)° from the plane of the benzopyran system. The mol­ecule is stabilized by an intra­molecular O—H⋯O hydrogen bond

Power Quality Improvement in 3P4W System Using Unified Power Quality Conditioner (UPQC) with P-Q Theory

Unified power quality conditioners (UPQCs) allow the mitigation of voltage and current disturbances that could affect sensitive electrical loads while compensating the load reactive power. Diverse control techniques have been proposed to evaluate the instantaneous output voltage of the series active power filter of the UPQC but, in most cases, these controllers only can compensate a kind of voltage disturbance. This paper presents a Unified Power Quality conditioner (UPQC) Design connected to three phase four wire system (3P4W). The neutral of series transformer used in the fourth wire for the 3P4W system. The neutral current that may flow toward transformer neutral point is compensated by using a four-leg voltage source inverter topology for shunt part. The series transformer neutral will be at virtual zero potential during all operating conditions. In this simulation we observe the power quality problems such as unbalanced voltage and current, harmonics by connecting non linear load to 3P4W system with Unified Power Quality conditioner. A new control strategy such as unit vector template is used to design the series APF to balance the unbalanced current present in the load currents by expanding the concept of single phase P-Q theory. The P-Q theory applied for balanced three phase system. And also be used for each phase of unbalanced system independently

Efficacy of calcium sodium phosphosilicate containing dentifrice in reducing dentin hypersensitivity compared to other dentifrices with dentin tubule occluding molecules: A systematic review

Purpose: To assess the effectiveness of calcium sodium phosphosilicate in reducing dentin hypersensitivity compared to other dentin tubule occluding molecules. Methods: A structured research question was formulated, and an electronic search of available literature was carried out via PubMed, Google Scholar, and Scopus. A hand search as well as a gray literature search were also carried out. The search produced a total of 67 articles. Of these, only eight articles were eligible to be included in our review. Risk of bias and study quality were checked using Cochrane tool. The review was registered in The International Prospective Register of Systematic Reviews (PROSPERO) under registration number CRD42018096200. Results: The results show a reduction in dentin hypersensitivity with calcium sodium phosphosilicate compared to many other molecules. However, nanohydroxyapatite showed a better desensitizing effect compared to Novamin. Conclusion: According to the available evidence, 5 % calcium sodium phosphosilicate containing toothpaste is more effective reducing dentin hypersensitivity compared to many other dentinal tubule occluding molecules