Los Ernobiinae de la Península Ibérica e Islas Baleares. 1a nota. El género Episernus C. G. Thomson, 1863 (Coleoptera: Ptinidae)

Whit the study of the genus Episernus C. G. Thomson, 1863 we begin the review of the species present in the Iberian Peninsula and Balearic Islands of the subfamily Ernobiinae Pic, 1912. In the Iberian Peninsula There are four species of Episernus recorded in the Iberian Peninsula, but one of them is based on dubious records. A relation of the consulted material and a redesription of the four species is given. A relation of the consulted material and a redesription of the four species is given and complemented with the habitus of all species, drawings of the antennae, maxillary and labial palps and aedeagus with detail of its pieces. Distribution and biology of species are also commented. Finally, to place genus Episernus within the subfamily Ernobiinae, a key to tribes of the subfamily and a key to genus of the tribe Ernobiini Pic, 1912 of the studied area is given.En el present treball s'inicia la revisió de les espècies presents a la península Ibèrica i Illes Balears de la subfamília Ernobiinae Pic, 1912. Es realitza l'estudi del gènere Episernus C. G. Thomson, 1863 amb tres espècies presents a l'àrea ibèrica més una de dubtosa, de les que es relaciona el material consultat, es dóna una redescripció de les mateixes, es comenta la seva distribució i biologia, i es complementa amb l'habitus de totes les espècies, dibuixos de les antenes, dels palps labials i maxiŀlars i dels edeagus amb detall de les seves peces. Per situar el gènere Episernus dins de la subfamília Ernobiinae es dóna la clau de tribus de la subfamília i la de gèneres de la tribu Ernobiini Pic, 1912 a nivell de la zona d'estudi.Con el presente trabajo se inicia la revisión de las especies presentes en la Península Ibérica e Islas Baleares de la subfamilia Ernobiinae Pic, 1912. Se realiza el estudio del género Episernus C. G. Thomson, 1863 con tres especies en el área ibérica mas una de dudosa presencia. De las que se relaciona el material consultado, se da una redescripción de las mismas, se comenta su distribución y biología, y se complementa con el habitus de todas las especies, dibujos de las antenas, de los palpos maxilares y labiales, y de los edeagos con detalle de sus piezas. Para situar el género Episernus dentro de la subfamilia Ernobiinae se da la clave de tribus de la subfamilia y la de géneros de la tribu Ernobiini Pic, 1912 a nivel de la zona de estudi

Oración fúnebre que en las honras que celebró la Santa Iglesia Cathedral de Salamanca a su... obispo... Joseph Zorrilla de San Martin en el dia 18 de noviembre de 1762

Copia digital. Valladolid : Junta de Castilla y León. Consejería de Cultura y Turismo, 2011Sign.: Sign.: A4, A-D

Revisión de la familia Salpingidae Leach, 1815 en el área iberobalear (Coleoptera)

Es realitza una revisió i actualització de la fauna de la família Salpingidae Leach, 1815 a la península Ibèrica i illes Balears, constituïda per 13 espècies pertanyents a 6 gèneres. Juntament amb les claus de separació genèrica i específica es relacionen els exemplars estudiats o revisats, es dóna una breu descripció de cada espècie, es comenta la seva distribució coneguda i s’aporten dades sobre la seva biologia. Es representa l’habitus i el mapa de distribució de cadascuna de les espècies. Així mateix s’estableix la sinonímia d’ Aglenus brunneus chilensis Dajoz, 1969 n. syn. amb Aglenus brunneus (Gyllenhal, 1813).The fauna of Salpingidae Leach family, 1815 in the Iberian Peninsula and the Balearic Islands (13 species appertaining to 6 genera) is reviewed and updated. Along with the generic and specific separation keys, the specimens studied or reviewed are listed, a brief description of each species is given, its known distribution is discussed, and data on its biology are provided. The habitus and the distribution map of each species are represented. The synonymy of Aglenus brunneus chilensis Dajoz, 1969 n. syn. with Aglenus brunneus (Gyllenhal, 1813) is established.Se revisa y actualiza la fauna de la familia Salpingidae Leach, 1815 en la Península Ibérica e Islas Baleares (13 especies pertenecientes a 6 géneros). Junto con las claves de separación genérica y específica se relacionan los ejemplares estudiados o revisados, se da una breve descripción de cada especie, se comenta su distribución conocida y se aportan datos sobre su biología. Se representa el habitus y el mapa de distribución de cada una de las especies. Asimismo se establece la nueva sinonimia de Aglenus brunneus chilensis Dajoz, 1969 n. syn. con Aglenus brunneus (Gyllenhal, 1813)

Wound Healing Modulation through the Local Application of Powder Collagen-Derived Treatments in an Excisional Cutaneous Murine Model

15 p.Wound healing includes dynamic processes grouped into three overlapping phases: inflammatory, proliferative, and maturation/remodeling. Collagen is a critical component of a healing wound and, due to its properties, is of great interest in regenerative medicine. This preclinical study was designed to compare the effects of a new collagen-based hydrolysate powder on wound repair to a commercial non-hydrolysate product, in a murine model of cutaneous healing. Circular excisional defects were created on the dorsal skin of Wistar rats (n = 36). Three study groups were established according to the treatment administered. Animals were euthanized after 7 and 18 days. Morphometric and morphological studies were performed to evaluate the healing process. The new collagen treatment led to the smallest open wound area throughout most of the study. After seven days, wound morphometry, contraction, and epithelialization were similar in all groups. Treated animals showed reduced granulation tissue formation and fewer inflammatory cells, and induction of vasculature with respect to untreated animals. After 18 days, animals treated with the new collagen treatment showed accelerated wound closure, significantly increased epithelialization, and more organized repair tissue. Our findings suggest that the new collagen treatment, compared to the untreated control group, produces significantly faster wound closure and, at the same time, promotes a slight progression of the reparative process compared with the rest of the groups.CIBER-BBNViscofan S.A

The conservation status and distribution of Mediterranean saproxylic beetles

The Mediterranean Red List assessment is a review of the conservation status at regional level of approximately 6,000 species of animals and plants. This report summarizes the results for a key group of Mediterranean biodiversity: saproxylic beetles. Despite their key role in the ecosystem´s health and food chain, saproxylic beetles are still largely misunderstood and the current information gaps on these species´ population status, trends, and distribution are a reflection on how little we still know about them. The geographical scope followed for this assessment is the Mediterranean region according to the Mediterranean Basin Biodiversity Hotspot, with the exception of the Macaronesian islands, which have not been included in this study. All the obligate saproxylic beetles endemic or almost endemic to the Mediterranean region – 320 species and 1 subspecies – are included

Associations of dietary energy density with body composition and cardiometabolic risk in children with overweight and obesity: role of energy density calculations, under-reporting energy intake and physical activity

This study examined (1) the association of dietary energy density from solid (EDS) and solid plus liquids (EDSL) with adiposity and cardiometabolic risk factors (CRF) in children with overweight and obesity, (2) the effect of under-reporting on the mentioned associations and (3) whether the association between ED and body composition and CRF is influenced by levels of physical activity. In a cross-sectional design, 208 overweight and obese children (8-12-year-old; 111 boys) completed two non-consecutive 24 h recalls. ED was calculated using two different approaches: EDS and EDSL. Under-reporters were determined with the Goldberg method. Body composition, anthropometry and fasting blood sample measurements were performed. Moderate to vigorous physical activity (MVPA) was registered with accelerometers (7-d-register). Linear regressions were performed to evaluate the association of ED with the previously mentioned variables. Neither EDS nor EDSL were associated with body composition or CRF. However, when under-reporters were excluded, EDS was positively associated with BMI (P=0 019), body fat percentage (P=0 005), abdominal fat (P=0 008) and fat mass index (P=0 018), while EDSL was positively associated with body fat percentage (P=0 008) and fat mass index (P=0 026). When stratifying the group according to physical activity recommendations, the aforementioned associations were only maintained for non-compliers. Cluster analysis showed that the low-ED and high-MVPA group presented the healthiest profile for all adiposity and CRF. These findings could partly explain inconsistencies in literature, as we found that different ED calculations entail distinct results. Physical activity levels and excluding under-reporters greatly influence the associations between ED and adiposity in children with overweight and obesity.The research leading to these results has received funding from la Caixa Foundation and Triptolemos Foundation, the Ministry of Health (FIS PI081297), the Research Network on Preventative Activities and Health Promotion (RD06/0018/ 0038), the Henning and Johan Throne-Holst Foundation (F. B. O.), the Spanish Ministry of Education, Culture and Sport (FPU14/03329 to M. M.), the Spanish Ministry of Economy and Competitiveness (DEP2013-47540 and DEP2016-78377-R; BES-2014-068829 to C. C.-S.), Fondo de Investigacion Sanitaria del Instituto de Salud Carlos III (PI13/01335), Fondos Estructurales de la Union Europea (FEDER), Una manera de hacer Europa, the Spanish Ministry of Science and Innovation (RYC-2011-09011 to F. B. O.), the University of Granada, Plan Propio de Investigacion 2016, Excellence Actions: Units of Excellence, Unit of Excellence on Exercise and Health (UCEES), Programa de Captacion de Talento - UGR Fellows (L. G.-M.), the SAMID III network, RETICS (PN I +D+ I 2017-2021). This study has been partially funded by the University of Granada, Plan Propio de Investigacion 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES), and by the Junta de Andalucia, Consejeria de Conocimiento, Investigacion y Universidades and European Regional Development Fund (ERDF), reference SOMM17/6107/UGR. ISCIII-Sub-Directorate General for Research Assessment and Promotion, the European Regional Development Fund (RD16/ 0022), the EXERNET Research Network on Exercise and Health in Special Populations (DEP2005-00046/ACTI), and the University of the Basque Country (GIU14/21). J. M.-G. is supported by the Spanish Ministry of Education, Culture and Sport (FPU14/06837). J. H. M. is supported by the Spanish Ministry of Education, Culture and Sport (FPU15/02645)

Genetic and environmental factors related to the development of myopic maculopathy in Spanish patients

High myopia and the subsequent degenerative changes of the retina, choroid, and sclera, known as myopic maculopathy (MM), are a serious visual problem in many Asian countries, and are beginning to be so in the south of Europe, especially in the Mediterranean. It is therefore necessary to carry out genetic and environmental studies to determine the possible causes of this disease. This study aims to verify if the genetic factors that have been most related to Asian populations are also associated in two Spanish cohorts. Eight SNPs from six genes (PAX6,SCO2,CCDC102B,BLID,chromosome 15q14, andCOL8A1) along with demographic, ophthalmic and environmental factors were analysed in two cohorts from a total of 365 highly myopic subjects and 177 control subjects. The genetic analysis showed thatCOL8A1SNP rs13095226 was associated with the development of choroidal neovascularization (CNV) and also seems to play an important role in the increase of axial length. The SNP rs634990 ofchromosome 15q14also showed a significant association with MM, although this was lost after the Bonferroni correction. Additional demographic and environmental factors, namely age, sex, smoking status, and pregnancy history, were also found to be associated with MM and CNV in this population

SOCIO-DEMOGRAPHIC VARIABLES, FEAR OF COVID-19, ANXIETY, AND DEPRESSION: PREVALENCE, RELATIONSHIPS AND EXPLANATORY MODEL IN THE GENERAL POPULATION OF SEVEN LATIN AMERICAN COUNTRIES

The COVID-19 pandemic has gravely impacted Latin America. A model was tested that evaluated the contribution of socio-demographic factors and fear of COVID-19 on anxiety and depression in samples of residents in seven Latin American countries (Argentina, Ecuador, Mexico, Paraguay, Uruguay, Colombia, and El Salvador). A total of 4,881 individuals, selected by convenience sampling, participated in the study. Moderate and severe levels of depressive symptoms and anxiety were identified, as well as a moderate average level of fear of COVID-19. In addition, it was observed that about a quarter of the participants presented symptoms of generalized anxiety disorder and a major depressive episode. Fear of COVID-19 significantly and positively predicted anxiety and depressive symptoms, whereas the effects of socio-demographic variables are generally low [χ2(287) = 5936.96, p < 0.001; RMSEA = 0.064 [0.062, 0.065]; CFI = 0.947; and SRMR = 0.050]. This suggests the need for the implementation of preventive actions in the general population of these countries, with the aim of reducing the prevalence of depressive, anxious and fearful symptoms related to COVID-19

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Una nueva localidad de Aulonothroscus laticollis (Rybinski, 1897) en Europa Occidental (Coleoptera: Throscidae).

Aulonothroscus laticollis (Rybinski, 1897) (Coleoptera: Throscidae), un raro elemento saproxílico con distribución discontinua, dispersa y disyunta asociado a bosques con elevado grado de naturalidad, ha sido descubierto en una nueva localidad en el país vasco-español.Aulonothroscus laticollis (Rybinski, 1897) (Coleoptera: Throscidae), a rare saproxylic element with a patchy, scattered and disjunct distribution, associated to forests with a high degree on naturalness, has been discovered in a new locality in the spanish Basque Country