20 research outputs found

    Compilation of Giant Electric Dipole Resonances Built on Excited States

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    Giant Electric Dipole Resonance (GDR) parameters for gamma decay to excited states with finite spin and temperature are compiled. Over 100 original works have been reviewed and from some 70 of which more than 300 parameter sets of hot GDR parameters for different isotopes, excitation energies, and spin regions have been extracted. All parameter sets have been brought onto a common footing by calculating the equivalent Lorentzian parameters. The current compilation is complementary to an earlier compilation by Samuel S. Dietrich and Barry L. Berman (At. Data Nucl. Data Tables 38(1988)199-338) on ground-state photo-neutron and photo-absorption cross sections and their Lorentzian parameters. A comparison of the two may help shed light on the evolution of GDR parameters with temperature and spin. The present compilation is current as of January 2006.Comment: 31 pages including 1 tabl

    Kematian Manusia Sebagai Inspirasi Dalam Seni Grafis

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    Kematian adalah suatu peristiwa yang paling hebat yang pasti akan terjadi atas diri manusia, melupakan mati atau tidak mengingat mati adalah suatu sikap yang tidak bertanggungjawab dari sudut pandang Islam. Semua manusia akan menemui kematian dalam hidupnya, ini adalah suatu kenyataan yang terjadi pada manusia. Maka persiapan menghadapi kematian menjadi penting dipertimbangkan untuk mendapatkan kebahagiaan dunia dan akhirat. Dalam kesenian, pesan-pesan agama, hubungan antara seni dan religi saling jalin menjalin sepanjang sejarah kehidupan manusia. Seni selalu hadir dalam setiap peradaban Islam, seperti, masjisd Nabawi di Madinah al Munawwarah yang sangat indah, atau penyampaian melalui lukisan “Arasbaque” dan karya seni lainnya. Konsep perwujudan dengan bentuk Tengkorak dan anatomi kerangka tulang manusia sebagai simbol yang dapat mewakili ide tentang kematian manusia, dipadu dengan objek pendukung lain dimaksudkan agar ilustrasi yang ingin dicapai dapat tersampaikan pesan dan makna ke dalam karya seni grafis. Dengan menggunakan teknik cetak saring atau serigrafi dalam visualisasinya dapat mendukung atau menghasilkan perwujudan karya yang maksimal sesuai dengan cita rasa, fantasi pengalaman estetis, dan kemampuan artistik yang diinginkan. Semua yang terjadi dari proses pembuatan karya seni Tugas Akhir ini merupakan respon atau tanggapan penulis terhadap seluruh permasalahan yang penulis alami dan amati atas realita yang terjadi di lingkungan sekitar. Penulis mencoba merefleksikan pengalaman pribadi penulis ke dalam karya-karya tugas akhir ini

    Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry

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    Breast cancer is a heterogeneous disease characterized by varying responses to therapeutic agents and significant differences in long-term survival. Thus, there remains an unmet need for early diagnostic and prognostic tools and improved histologic characterization for more accurate disease stratification and personalized therapeutic intervention. This study evaluated a comprehensive metabolic phenotyping method in breast cancer tissue that uses desorption electrospray ionization mass spectrometry imaging (DESI MSI), both as a novel diagnostic tool and as a method to further characterize metabolic changes in breast cancer tissue and the tumor microenvironment. In this prospective single-center study, 126 intraoperative tissue biopsies from tumor and tumor bed from 50 patients undergoing surgical resections were subject to DESI MSI. Global DESI MSI models were able to distinguish adipose, stromal, and glandular tissue based on their metabolomic fingerprint. Tumor tissue and tumor-associated stroma showed evident changes in their fatty acid and phospholipid composition compared with normal glandular and stromal tissue. Diagnosis of breast cancer was achieved with an accuracy of 98.2% based on DESI MSI data (PPV 0.96, NVP 1, specificity 0.96, sensitivity 1). In the tumor group, correlation between metabolomic profile and tumor grade/hormone receptor status was found. Overall classification accuracy was 87.7% (PPV 0.92, NPV 0.9, specificity 0.9, sensitivity 0.92). These results demonstrate that DESI MSI may be a valuable tool in the improved diagnosis of breast cancer in the future. The identified tumor-associated metabolic changes support theories of de novo lipogenesis in tumor tissue and the role of stroma tissue in tumor growth and development and overall disease prognosis. Cancer Res; 75(9); 1828–37. ©2015 AACR
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