Gestión de la calidad educativa y la competencia digital en una institución educativa del distrito de el Agustino, Lima 2021

El objetivo de esta investigación es determinar la relación entre gestión de la calidad educativa y competencia digital en una institución educativa del distrito de El Agustino, 2021. El presente estudio tiene una orientación de enfoque cuantitativo, tipo básica, diseño no experimental y alcance correlacional. La muestra de 50 docentes se les extendió una encuesta con 56 preguntas conteniendo las dos variables, el cuestionario fue escrutado por tres expertos, los que validaron su aplicabilidad, el producto arrojó para la prueba de fiabilidad del Alfa de Cronbach en la primera variable de 0, 769 y para la segunda variable fue de 0,844 se utilizó la prueba de correlación de Rho de Sperman que determinó el grado de 0,812 con un 99% de confianza al 0.01 rechazándose la hipótesis nula y aceptándose la hipótesis alternativa. Se determina que la gestión de la calidad educativa se asocia significativamente con la competencia digital en una Institución Educativa

The modulating effect of bruxism as a form of suppressed hostility on depression in a selected population of tension type headache (ttha) and craniomandibular disorders (cmds) individuals. O efeito modulador do bruxismo como uma forma de hostilidade reprimida numa população seleta com dor de cabeça por tensão muscular e distúrbios craniomandibulares (dcms).

AIMS: explore the hypothesis that bruxism and depression are forms of suppressed hostility in individuals presenting Craniomandibular Disorders (CMDs) and Tension-type Headache (TTHa). METHODS: We evaluated a group of 100 Craniomandibular Disorders and Tension-Type Headache individuals, a group of 38 CMDs and Facial Pain individuals and a group of 23 No Craniomandibular Disorders No Facial Pain individuals. Clinical examination, questionnaires, history of signs and symptoms, the Beck Depression Inventory (BDI) and the Cook-Medley Inventory (HO) were used to gather data. RESULTS: The frequency of Tension Type Headache was about 43.5% in the group of 230 Craniomandibular Disorder patients. Mean scores in hostility were 19.0, 17.7 and 17.2 in the groups presenting Tension-Type Headache and CMDs, CMDs and Facial Pain and No CMDs no Pain, respectively. Mean scores in depression were about 12.0, 9.1 and 5.7 respectively in the same groups. Mean scores in bruxism were about 12.9, 8.2 and 6.8, respectively in the same groups. The strongest correlation between bruxism and depression were observed in the TTHa group (r=0.4, p<0.0001) and in the Non CMD Non Pain group (r=0.48, p<0.02). CONCLUSION: Depression is a better indicator of hostility in subgroups presenting TTHa. Scores in bruxism and depression as a form of suppressed hostility are higher in CMDs and TTHa individuals than in controls without TTHa. Because scores in bruxism were higher in TTHa and CMDs individuals, there is a strong and positive association between bruxism and TTHa in individuals with concomitant Craniomandibular disorders

Loss of p27 phosphorylation at Ser10 accelerates early atherogenesis by promoting leukocyte recruitment via RhoA/ROCK

Reduced phosphorylation of the tumor suppressor p27(Kip1) (p27) at serine 10 (Ser10) is a hallmark of advanced human and mouse atherosclerosis. Apolipoprotein E-null mice defective for this posttranslational modification (apoE(-/-)p27Ser10Ala) exhibited increased atherosclerosis burden at late disease states. Here, we investigated the regulation of p27 phosphorylation in Ser10 at the very initial stages of atherosclerosis and its impact on endothelial-leukocyte interaction and early plaque formation. Hypercholesterolemia in fat-fed apoE(-/-) mice is associated with a rapid downregulation of p27-phospho-Ser10 in primary endothelial cells (ECs) and in aorta prior to the development of macroscopically-visible lesions. We find that lack of p27 phosphorylation at Ser10 enhances the expression of adhesion molecules in aorta of apoE(-/-) mice and ECs, and augments endothelial-leukocyte interactions and leukocyte recruitment in vivo. These effects correlated with increased RhoA/Rho-associated coiled-coil containing protein kinase (ROCK) signaling in ECs, and inhibition of this pathway with fasudil reduced leukocyte-EC interactions to control levels in the microvasculature of p27Ser10Ala mice. Moreover, apoE(-/-)p27Ser10Ala mice displayed increased leukocyte recruitment and homing to atherosusceptible arteries and augmented early plaque development, which could be blunted with fasudil. In conclusion, our studies demonstrate a very rapid reduction in p27-phospho-Ser10 levels at the onset of atherogenesis, which contributes to early plaque build-up through RhoA/ROCK-induced integrin expression in ECs and enhanced leukocyte recruitment.Spanish Ministry of Economy and Competitivity (MINECO) [SAF2010-16044, SAF2013-46663-R]; Fondo Europeo de Desarrollo Regional (FEDER); Instituto de Salud Carlos III [RD12/0042/0028]; FPU predoctoral fellowship from MINECO; MINECO; Pro-CNIC FoundationS

Can the X(4350) narrow structure be a 1−+1^{-+} exotic state?

Using the QCD sum rules we test if the new narrow structure, the X(4350) recently observed by the Belle Collaboration, can be described as a $J^{PC}=1^{-+}$ exotic $D_s^*D_{s0}^*$ molecular state. We consider the contributions of condensates up to dimension eight, we work at leading order in $\alpha_s$ and we keep terms which are linear in the strange quark mass $m_s$. The mass obtained for such state is $m_{D_s^*{D}_{s0}^*}=(5.05\pm 0.19)$ GeV. We also consider a molecular $1^{-+}, D^{*}{D}_0^{*}$ current and we obtain $m_{D^*{D}_0^*}=(4.92\pm 0.08)$ GeV. We conclude that it is not possible to describe the X(4350) structure as a $1^{-+} D_s^*{D}_{s0}^*$ molecular state.Comment: 7 pages, 4 figure

Measurements and modelling of radio propagation in subway tunnels

The work presented in this article is focused on the RF measurement campaign carried out in several subway tunnels in Metro Madrid (Spain). Most common segments such as straight lines, curves and passing through station as well as other unique scenarios in metropolitan lines were the selected locations during this campaign. Measurements were conducted in tunnels of diverse cross section shapes and taken at three frequency bands: 900 MHz, 2.4GHz and 5.7 GHz for both horizontal and vertical polarization

NUMERICAL ANALYSIS OF THE IN-CYLINDER FLOW FIELD AND COMPARISON WITH EXPERIMENTAL DATA IN A SINGLE CYLINDER RESEARCH ENGINE

In this paper, the 3D numerical analysis of the flow field in a single cylinder research engine with optical access, running cold flow, is presented. The simulations were carried out in the commercial software Star-CD with es-ICE module and the two different turbulence models: RNG-k-ε and k-w SST were compared with experimental data of the engine running at 1000 rpm in motored conditions. A grid independency study is presented using five grids varying from approximately 500,000 to 1,500,000 cells on piston bottom dead center. An optical window inside the engine cylinder was used to measure the velocity components along the crank angle with the PIV technique and a comparison was made with calculated velocity curves. Moreover, a qualitative analysis of the scalar flow field in the region of interest is presented. The results showed a better agreement with the RNG-k-ε and experimental mean velocity magnitude curve than k-ω-SST. However, the qualitative scalar velocity field of the k-ω model captured more details of the flow than the k-ε model

NUMERICAL ANALYSIS OF THE IN-CYLINDER FLOW FIELD AND COMPARISON WITH EXPERIMENTAL DATA IN A SINGLE CYLINDER RESEARCH ENGINE

In this paper, the 3D numerical analysis of the flow field in a single cylinder&nbsp;research engine with optical access, running cold flow, is presented. The simulations were&nbsp;carried out in the commercial software Star-CD with es-ICE module and the two different&nbsp;turbulence models: RNG-k-ε and k-w SST were compared with experimental data of the&nbsp;engine running at 1000 rpm in motored conditions. A grid independency study is presented&nbsp;using five grids varying from approximately 500,000 to 1,500,000 cells on piston bottom dead&nbsp;center. An optical window inside the engine cylinder was used to measure the velocity components along the crank angle with the PIV technique and a comparison was made with&nbsp;calculated velocity curves. Moreover, a qualitative analysis of the scalar flow field in the&nbsp;region of interest is presented. The results showed a better agreement with the RNG-k-ε and&nbsp;experimental mean velocity magnitude curve than k-ω-SST. However, the qualitative scalar&nbsp;velocity field of the k-ω model captured more details of the flow than the k-ε model

Synthesis of 2D porous crystalline materials in simulated microgravity

Altres ajuts: the ICN2 is funded by the CERCA programme/Generalitat de Catalunya. The GIWAXS experiments were conducted on the NCD-SWEET beamline of the ALBA synchrotron, Spain. GIWAXS experiments of Ni(HITP) and COF-TAPB-BTCA were performed at the NCD-SWEET beamline at ALBA Synchrotron with the collaboration of ALBA staff.To date, crystallization studies conducted in space laboratories, which are prohibitively costly and unsuitable to most research laboratories, have shown the valuable effects of microgravity during crystal growth and morphogenesis. Herein, an easy and highly efficient method is shown to achieve space-like experimentation conditions on Earth employing custom-made microfluidic devices to fabricate 2D porous crystalline molecular frameworks. It is confirmed that experimentation under these simulated microgravity conditions has unprecedented effects on the orientation, compactness and crack-free generation of 2D porous crystalline molecular frameworks as well as in their integration and crystal morphogenesis. It is believed that this work will provide a new "playground" to chemists, physicists, and materials scientists that desire to process unprecedented 2D functional materials and devices

Oxygen supply in Bacillus thuringiensis fermentations: bringing new insights on their impact on sporulation and delta-endotoxin production

The growth kinetics, sporulation, and toxicity of Bacillus thuringiensis var. israelensis were evaluated through the analysis of batch cultures with different dissolved oxygen (DO) profiles. Firstly, DO was maintained constant at 5%, 20%, or 50% throughout fermentation in order to identify the most suitable one to improve the main process parameters. Higher biomass concentration, cell productivity, and cell yield based on glucose were obtained with 50% DO. The higher aeration level also resulted in higher spore counts and markedly improved the toxic activity of the fermentation broth, which was 9-fold greater than that obtained with 5% DO (LC50 of 39 and 329 mg/L, respectively). Subsequently, using a two-stage oxygen supply strategy, DO was kept at 50% during the vegetative and transition phases until the maximum cell concentration was achieved. Then, DO was changed to 0%, 5%, 20%, or 100% throughout sporulation and cell lysis phases. The interruption of oxygen supply strongly reduced the spore production and thoroughly repressed the toxin synthesis. On the contrary, when DO was raised to 100% of saturation, toxic activity increased approximately four times (LC50 of 8.2 mg/L) in comparison with the mean values reached with lower DO levels, even though spore counts were lower than that from the 50% DO assay. When pure oxygen was used instead of normal air, it was possible to obtain 70% of the total biomass concentration achieved in the air assays; however, cultures did not sporulate and the toxin synthesis was consequently suppressed.FAPERJ (Fundacao Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro, Brazil