7,123 research outputs found

    A closer look at the determinologisation process

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    UIDB/03213/2020 UIDP/03213/2020This paper arises within the current communication urgency experienced through-out the pandemic. From its onset, several new lexical units have permeated the over-all media discourse, as well as social media and other channels. These units conveyinformation to the public regarding the ‘severe acute respiratory syndrome’ namely COVID-19. In addition to its worldwide impact healthwise, the pandemic generates noteworthy influence in the linguistic landscape, and as a result, a significant number of neologisms have emerged. Within the scope of our ongoing research, we identify the neologisms in European Portuguese that are related to the term COVID-19 via form or meaning. However, not all the new lexical units identified in our corpus containing COVID-19 in its formation can unequivocally be regarded as neoterms (terminological neologisms). Accordingly, this article aims not only to reflect on thedistinction between neologism and neoterm but also to explore the determinologisa-tion process that several of these new lexical units experience.publishersversionpublishe

    LSP in theory and practice

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    UIDB/03213/2020 UIDP/03213/2020Book of abstracts and Program of the 23rd International Conference on Languages for Specific Purposes (LSP 2022: Shaping knowledge through language: LSP in theory and practice), which took place at NOVA University Lisbon, Portugal (CAN – Colégio Almada Negreiros, 1099 – 032 Lisboa).publishersversionpublishe

    The advent of a new lexicographical portuguese project

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    UID/LIN/03213/2013MORDigital is a newly funded Portuguese lexicographic project that aims to produce high-quality and searchable digital versions of the first three editions (1789; 1813; 1823) of the Diccionario da Lingua Portugueza by António de Morais Silva, preserving and making accessible this important work of European heritage. This paper will describe the current state of the art, the project, its objectives and the methodology proposed, the latter of which is based on a rigorous linguistic analysis and will also include steps necessary for the ontologisation of knowledge contained in and relating to the text. A section will be dedicated to the various investigation domains of the project description. The output of the project will be made available via a dedicated platform.publishersversionpublishe

    A preliminary analysis of the wear pathways of sliding contacts on temporomandibular joint total joint replacement prostheses

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    In the last years, several materials and design have been assessed in an attempt to improve the mechanical performance of temporomandibular joint total joint replacement (TMJ TJR) prostheses. However, the wear of the TMJ TJR condyle to the polymer-based fossa component during loading and sliding movements. That promotes the release of debris and risks of toxicity to the surrounding tissues. The purpose of this study was to perform a narrative literature review on the wear of TMJ TJR sliding contacts and potential toxicity of metallic debris to the patients. Previous studies reported a significant deterioration of the sliding contact surfaces of TMJ TJR prostheses. Material loss as a result of wear can cause a TMJ TJR condyle/fossa mismatch and the modification of the contact pressure and chewing loading. As a further consequence of wear, metal particles are released to the surrounding tissues with a high risk of local tissue and systemic toxicity through the bloodstream. The presence of particles induces the stimulation of inflammatory reactions depending on the concentration and size of debris. Thus, CoCr-based condyle release metallic ions and sub-micron particles that can be engulfed by macrophages or internalized by other tissue cells. The wear and material loss of TMJ TJR could be decreased by design optimization and novel materials with low friction and contact pressure. That consequently decrease the amount of metallic ions and particles to the surrounding tissues, preventing peri-prosthetic inflammatory reactions.This study was supported by FCT-Portugal (UID/EEA/04436/2013, NORTE-01-0145- FEDER-000018—HAMaBICo, POCI-01-0145-FEDER-031035_LaserMULTICER), SFRH/BPD/123769/ 2016 and CNPq-Brazil (CNPq/UNIVERSAL/421229/2018-7)

    Effect Of 4-(n,n-dimethylamino)phenethyl alcohol on degree of conversion and cytotoxicity of photo-polymerized CQ-based resin composites

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    FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOThe aim of this study was to evaluate the degree of conversion (DC) and the cytotoxicity of photo-cured experimental resin composites containing 4-(N,N-dimethylamino)phenethyl alcohol (DMPOH) combined to the camphorquinone (CQ) compared with ethylamine benzoate (EDAB). The resin composites were mechanically blended using 35 wt% of an organic matrix and 65 wt% of filler loading. To this matrix was added 0.2 wt% of CQ and 0.2 wt% of one of the reducing agents tested. 5x1 mm samples (n=5) were previously submitted to DC measurement and then pre-immersed in complete culture medium without 10% (v/v) bovine serum for 1 h or 24 h at 37 °C in a humidifier incubator with 5% CO2 and 95% humidity to evaluate the cytotoxic effects of experimental resin composites using the MTT assay on immortalized human keratinocytes cells. As a result of absence of normal distribution, the statistical analysis was performed using the nonparametric Kruskal-Wallis to evaluate the cytotoxicity and one-way analysis of variance to evaluate the DC. For multiple comparisons, cytotoxicity statistical analyses were submitted to Student-Newman-Keuls and DC analysis to Tukey's HSD post-hoc test (=0.05). No significant differences were found between the DC of DMPOH (49.9%) and EDAB (50.7%). 1 h outcomes showed no significant difference of the cell viability between EDAB (99.26%), DMPOH (94.85%) and the control group (100%). After 24 h no significant difference were found between EDAB (48.44%) and DMPOH (38.06%), but significant difference was found compared with the control group (p>0.05). DMPOH presented similar DC and cytotoxicity compared with EDAB when associated with CQ.The aim of this study was to evaluate the degree of conversion (DC) and the cytotoxicity of photo-cured experimental resin composites containing 4-(N,N-dimethylamino)phenethyl alcohol (DMPOH) combined to the camphorquinone (CQ) compared with ethylamine benzoate (EDAB). The resin composites were mechanically blended using 35 wt% of an organic matrix and 65 wt% of filler loading. To this matrix was added 0.2 wt% of CQ and 0.2 wt% of one of the reducing agents tested. 5x1 mm samples (n=5) were previously submitted to DC measurement and then pre-immersed in complete culture medium without 10% (v/v) bovine serum for 1 h or 24 h at 37 °C in a humidifier incubator with 5% CO2 and 95% humidity to evaluate the cytotoxic effects of experimental resin composites using the MTT assay on immortalized human keratinocytes cells. As a result of absence of normal distribution, the statistical analysis was performed using the nonparametric Kruskal-Wallis to evaluate the cytotoxicity and one-way analysis of variance to evaluate the DC. For multiple comparisons, cytotoxicity statistical analyses were submitted to Student-Newman-Keuls and DC analysis to Tukey's HSD post-hoc test (=0.05). No significant differences were found between the DC of DMPOH (49.9%) and EDAB (50.7%). 1 h outcomes showed no significant difference of the cell viability between EDAB (99.26%), DMPOH (94.85%) and the control group (100%). After 24 h no significant difference were found between EDAB (48.44%) and DMPOH (38.06%), but significant difference was found compared with the control group (p>0.05). DMPOH presented similar DC and cytotoxicity compared with EDAB when associated with CQ256538542FAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULOFAPESP - FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE SÃO PAULO2013/04241-

    Diagnosis, management, and follow-up of extensive dermoid cyst of the submental region

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    Dermoid cyst (DC) is a cystic lesion of developmental origin and uncertain etiology that rarely affects the floor of the mouth. We report a case of a large lesion found in the submental and submandibular region in a 25-year-old male patient. Computed tomography revealed extensive hypodense lesion in the submental and submandibular space without peripheral enhancement. The microscopical analysis showed a cystic cavity lined by orthokeratinized stratified squamous epithelium. The cystic capsule was composed of dense fibrous connective tissue containing cutaneous attachments, such as sebaceous and sweat glands. The diagnosis of DC was made. The differential diagnosis of expansive sublingual lesions can be clinically challenging due to the similarity with several lesions frequently observed in this region. Herein, we describe a case of extensive DC arising in the floor of the mouth, presenting clinical, imaging, and microscopical features

    Generalized hereditary gingival fibromatosis in a child: clinical, histopathological and therapeutic aspects

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    Hereditary gingival fibromatosis (HGF) is a rare genetic condition characterized by slow and progressive gingival enlargement. The gingival overgrowth often delays teeth eruption and may cause serious functional and aesthetic problems. We reported a case of a 10-year-old female child presenting a generalized gingival enlargement covering almost all the maxillary and mandibular teeth and resulted in problems for swallowing, speaking, and poor aesthetics. An incisional biopsy was performed and revealed a hypocellular and hypovascular dense collagenous tissue covered by squamous epithelium exhibiting acanthosis and elongated rete ridges. The diagnosis was HGF. The treatment instituted was an association of gingivectomy with a rigorous program of oral hygiene and follow-up. Herein, we describe a rare non-syndromic case of generalized HGF, including clinical and microscopical features, as well as highlighting the importance of correct diagnosis of this genetic condition

    Subcutaneous Adipose Tissue Plays A Beneficial Effect On Subclinical Atherosclerosis In Young Survivors Of Acute Lymphocytic Leukemia.

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    The aim of this study was to evaluate the relationship between body composition, metabolic profile, adipokines, and carotid intima-media thickness (cIMT) in young survivors of childhood acute lymphocytic leukemia (ALL). This cross-sectional study compared 55 ALL survivors, of chronological age between 15 years and 24 years, assigned into two groups according to the exposure to cranial radiation therapy (CRT; 25 irradiated and 30 nonirradiated) with 24 leukemia-free controls, and assessed body fat mass (dual-energy X-ray absorptiometry), computed tomography scan-derived abdominal adipose tissue, lipid profile, blood pressure (BP), adipokines, and cIMT by a multiple regression analysis. Treatment with CRT had an effect on all of the variables derived from the computed tomography scan: visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) (P<0.050). In a multiple linear regression model, cIMT positively correlated with exposure to CRT (P=0.029), diastolic BP (P=0.016), and leptin-to-adiponectin ratio (P=0.048), while negatively related to SAT (P=0.007). In young survivors of childhood ALL, CRT modified the distribution of fat and played a critical role in determining cIMT. Leptin-to-adiponectin ratio, a biomarker of abdominal obesity and metabolic syndrome, and diastolic BP also influenced cIMT, a marker of subclinical atherosclerosis. Nonetheless, adiposity-associated vascular disease might be attenuated by SAT. Changes in body fat must be evaluated in this group of patients in the early course of survivorship in order to avoid premature cardiovascular disease associated with atherosclerosis. Yet, further research as regards the possible protective effect of SAT on vascular disease is warranted.11479-48

    On Ti-18Si-6B and Ti-7.5Si-22.5B powder alloys prepared by high-energy ball milling and sintering

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    Recently, a new ternary phase was discovered in the Ti-Si-B system, located near the Ti6Si2B composition. The present study concerns the preparation of titanium alloys that contain such phase mixed with &#945;-titanium and other intermetallic phases. High-purity powders were initially processed in a planetary ball-mill under argon atmosphere with Ti-18Si-6B and Ti-7.5Si-22.5B at. (%) initial compositions. Variation of parameters such as rotary speed, time, and ball diameters were adopted. The as-milled powders were pressureless sintered and hot pressed. Both the as-milled and sintered materials were characterized by X-ray diffraction, scanning electron microscopy and energy-dispersive spectrometry. Sintered samples have presented equilibrium structures formed mainly by the &#945;-Ti+Ti6Si2B+Ti5Si3+TiB phases. Silicon and boron peaks disappear throughout the milling processes, as observed in the powder diffraction data. Furthermore, an iron contamination of up to 10 at. (%) is measured by X-ray spectroscopy analysis on some regions of the sintered samples. Density, hardness and tribological results for these two compositions are also presented here

    Acurácia do diagnóstico clínico de lesões orais malignas em um Centro de Referência do Nordeste Brasileiro

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    Objetivo: Avaliar a acuráciadodiagnósticoclínico comparando com o diagnóstico histopatológicodelesõesmalignasanalisadasnoLaboratóriodePatologiaOraldoCentrodeReferênciasdeLesõesOraisdaUniversidadeEstadualdeFeiradeSantana.Metodologia: Foi realizado um estudo de validade de diagnóstico em uma amostracompostapor 1.926casosqueforamsubmetidosàbiópsias oraisnoperíodode 2005 a 2017.Resultados: Observou-sequeasensibilidadedodiagnósticoclíniconadetecçãodelesõesmalignasfoide 75% eaespecificidadefoide 97%. Ovalorpreditivopositivofoide 77% eovalorpreditivonegativofoide 95%. Ovalordaacuráciafoide 95%, correspondendo assimaumaacuráciaalta. Os indivíduos com lesões malignas eram dosexomasculino (65,9%) e acima de 40 anos (93,2%). Ao analisar as características clínicas das lesões, foi observado que a localização mais frequente foi a língua (29,4%), com coloração vermelha (54,9%), sendoaúlcera (50%) alesãofundamentalmaiscomum. Aslesõesseapresentarammaioresque 10cm(72,7%) e54,4% daslesõesestiverampresenteshá maisde 12 mesesna cavidadeoral.Conclusões: O exame clínico demonstrou uma alta precisão na identificação de lesões malignas em cavidade oral, demonstrando assim a importância do conhecimento prévio das características das lesões por estudantes e profissionais da Odontologia. Entretanto, apesar de sua validade, não se deve abrir mão do exame histopatológico para a confirmação da suspeita clínica
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