Geriatric Medication Therapy: Weighing the Evidence versus Best Practice

Goals: The goal of this article is to provide a review of available evidence for safe prescribing in older adults and recommend medication therapies based on anticipated pharmacokinetic/physiologic changes in this population

Staff Nurses Lack of Knowledge and Opioid Use at the Veteran Administration

AbstractStaff Nurses’ Lack of Knowledge and Opioid Use at the Veteran Administration By Cathy Ramey MS, University of Phoenix, 2014BS, Chamberlain University, 2008 Dissertation Submitted in Partial Fulfillment Of the Requirements for the Degree of Doctor of Nursing Practice Walden University November 2022 Abstract Opioids are often prescribed for pain management, which may have led to high rates of opioid addiction among veteran populations. The problem identified in this DNP project was the nurses’ lack of knowledge regarding pain management and the use of opioids in the veteran’s (VA) hospital where the project commenced. Using the Analyse, Design, Develop, Implement, and Evaluate (ADDIE) model as a conceptual framework, the purpose of this DNP project was to plan, implement, and evaluate a continuing education(CE) program on pain management and opioid addiction for the staff nurses of the VA hospital for which the project was developed. One practice-focused question guided this project, whether there would be an increase in knowledge related to pain management and opioid addiction after the implementation of a CE program, as evidenced by a pre-test or post-test survey. Six staff nurse participants were given pre-test and post-test surveys, and scores were compared using paired samples t-test to determine whether there was a significant increase in knowledge. Results indicated that nurses demonstrated a12.9% increase in knowledge. Therefore, this project addressed the identified gap by increasing the awareness among VA nurses regarding pain management and appropriate prescription of opioids while reducing the improper prescription of opioids for pain management among VA patients. Better pain management can occur with alternative strategies, and this knowledge may be instrumental in addressing the opioid crisis. As a result of this project, positive social change may occur as patients may be impacted positively when they experience better pain management, improved health outcomes, and reduced rates of addiction and opioid misuse or overdose

Review: The Journal of Dramaturgy, volume 20, 2009/2010

Contents include: Recognizing Toward a Dramaturgical Sensibility, Geoff Proehl, recipient of the 2009 ATHE Outstanding Book Award; Geoff Proehl\u27s Acceptance Speech, Association for Theatre in Higher Education Awards Ceremony August 10, 2009; Millennial Dramaturgy, A conversation about the new book Dramaturgy and Performance; Creating Sub/Text, Dramaturging the ReStaged Festival; Dramaturgy and Interdisciplinary Learning, A Case Study of Russian Theatre and Politics; Thinking about Theatre Photography; Theatre / Photography. Issue editors: D.J. Hopkins, Sydney Cheek O\u27Donnell, Lauren Beckhttps://soundideas.pugetsound.edu/lmdareview/1040/thumbnail.jp

Reflections on the 'History and Historians' of the black woman's role in the community of slaves: enslaved women and intimate partner sexual violence

Taking as points of inspiration Peter Parish’s 1989 book, Slavery: History and Historians, and Angela Davis’s seminal 1971 article, “Reflections on the black woman’s role in the community of slaves,” this probes both historiographically and methodologically some of the challenges faced by historians writing about the lives of enslaved women through a case study of intimate partner violence among enslaved people in the antebellum South. Because rape and sexual assault have been defined in the past as non-consensual sexual acts supported by surviving legal evidence (generally testimony from court trials), it is hard for historians to research rape and sexual violence under slavery (especially marital rape) as there was no legal standing for the rape of enslaved women or the rape of any woman within marriage. This article suggests enslaved women recognized that black men could both be perpetrators of sexual violence and simultaneously be victims of the system of slavery. It also argues women stoically tolerated being forced into intimate relationships, sometimes even staying with “husbands” imposed upon them after emancipation

Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens.

There is urgent need for new drug regimens that more rapidly cure tuberculosis (TB). Existing TB drugs and regimens vary in treatment-shortening activity, but the molecular basis of these differences is unclear, and no existing assay directly quantifies the ability of a drug or regimen to shorten treatment. Here, we show that drugs historically classified as sterilizing and non-sterilizing have distinct impacts on a fundamental aspect of Mycobacterium tuberculosis physiology: ribosomal RNA (rRNA) synthesis. In culture, in mice, and in human studies, measurement of precursor rRNA reveals that sterilizing drugs and highly effective drug regimens profoundly suppress M. tuberculosis rRNA synthesis, whereas non-sterilizing drugs and weaker regimens do not. The rRNA synthesis ratio provides a readout of drug effect that is orthogonal to traditional measures of bacterial burden. We propose that this metric of drug activity may accelerate the development of shorter TB regimens