A guide to super-resolution fluorescence microscopy

For centuries, cell biology has been based on light microscopy and at the same time been limited by its optical resolution. However, several new technologies have been developed recently that bypass this limit. These new super-resolution technologies are either based on tailored illumination, nonlinear fluorophore responses, or the precise localization of single molecules. Overall, these new approaches have created unprecedented new possibilities to investigate the structure and function of cells

Event-Driven Monitoring of Parallel Systems

The dynamic behavior of parallel programs can be disclosed by event-driven monitoring. A hybrid monitoring method for analyzing the functional behavior and the performance of programs in parallel and distributed systems is presented. The paper contains a description of a scalable hardware monitor system (ZM4) and a software package for event trace evaluation (SIMPLE) which make our concepts available to programmers, assisting them in debugging and tuning of their code. A short survey of related monitor systems highlights the distinguishing features of our implementation. As an application of our monitoring and evaluation system, the analysis of a parallel ray tracing program running on the SUPRENUM multiprocessor is described. Models can help to increase the efficiency when writing parallel programs. We show that monitoring and modeling both rely on a common abstraction of a system's dynamic behavior and therefore can be integrated to one comprehensive methodology. This methodology is ..

Un nuevo material fotopolimerizable

Hoy en día el odontólogo dispone de un gran número de sistemas de pernos y de diferentes métodos para la reconstrucción de la parte del muñón de un diente. Si se ha de fabricar en técnica directa una estructura de perno colado individualmente se necesita un material de modelado fiel a la forma y estable. A continuación se presenta un nuevo material fotopolimerizable para el modelado directo de estructuras, que posee propiedades de trabajo mucho mejores que los materiales sintéticos de modelado convencionales a base de PMMA. Colar pernos y muñones a la ¿antigua¿ sigue teniendo todavía bastantes defensores, pese a que mientras tanto hay gran número de alternativas (lista de los sistemas relevantes de pernos, véase ZP 8, 2004)

Tools for a Model-driven Instrumentation for Monitoring

The performance of parallel and distributed systems depends significantly on how the programs ' execution is dynamically organized. Therefore, performance evaluation and efficient programming of parallel and distributed systems need the analysis of the internal behavior of such systems. For this purpose event-driven monitoring is an appropriate technique. Eventdriven monitoring reduces the dynamic internal behavior of the system to some important events, which are recorded in event traces. The instrumentation of the object program, i.e. the definition of events, depends on the respective intention of the analysis. In most cases the instrumentation will be done intuitively based on professional experience. In this paper a concept for a model-driven execution of event-driven monitoring is presented. It leads to tools for systematic and automatic instrumentation. 1. Introduction The use of more and more complex computer systems, for example multiprocessor or multicomputer systems, needs ..