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An injectable bone marrow-like scaffold enhances T cell immunity after hematopoietic stem cell transplantation.
- Author
- Publication venue
- eScholarship, University of California
- Publication date
- 01/03/2019
- Field of study
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for multiple disorders, but deficiency and dysregulation of T cells limit its utility. Here we report a biomaterial-based scaffold that mimics features of T cell lymphopoiesis in the bone marrow. The bone marrow cryogel (BMC) releases bone morphogenetic protein-2 to recruit stromal cells and presents the Notch ligand Delta-like ligand-4 to facilitate T cell lineage specification of mouse and human hematopoietic progenitor cells. BMCs subcutaneously injected in mice at the time of HSCT enhanced T cell progenitor seeding of the thymus, T cell neogenesis and diversification of the T cell receptor repertoire. Peripheral T cell reconstitution increased ~6-fold in mouse HSCT and ~2-fold in human xenogeneic HSCT. Furthermore, BMCs promoted donor CD4+ regulatory T cell generation and improved survival after allogeneic HSCT. In comparison to adoptive transfer of T cell progenitors, BMCs increased donor chimerism, T cell generation and antigen-specific T cell responses to vaccination. BMCs may provide an off-the-shelf approach for enhancing T cell regeneration and mitigating graft-versus-host disease in HSCT
Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries
- Author
- Abad-Motos Ane
- Abbas Ahmed M.
- Abbas Mostafa
- Abbasi Mujeeb
- Abbott Tom
- Abd Karim Muhammad Fairuz Shah
- Abdalaal Ibrahim
- Abdel-Galil Khalid
- Abdelemam Rania
- Abdelgawad Abdalrahman
- Abdelkarim Maryam
- Abdelkhalek Mohamed
- Abdelmageed Abdelfatah
- Abdelmawgoud Sherif
- Abdelmohsen Sarah
- Abdelrahman Ahmed Saber
- Abdelrahman Mostafa
- Abdelwahab Khaled
- Abdou Hossam
- Abdulai Darling Ramatu
- Abdulkhaleq Marwa
- Abdullah Bahiyah
- Abdulsalam Khalifa
- Abdulsalam Shuaib
- Abdur-Rahman Lukman
- Abdus-Salam Rukiyat
- Abdussalam Hameedat Opeyemi
- Abebrese John Tabiri
- Abeldaño Ariel
- Abou-Khalil Jad
- Abou-Taleb Hisham
- Abozid Anwaar
- Abozied Hesham
- Abrate Alberto
- Abu-Zaid Ahmed
- Abubakar Mohammed Kabir
- Abud Burçin
- Abuzaid Mohammed
- Adam Albushra Altayeb
- Adamina Michel
- Adamou Harissou
- Adamu Auwal
- Adamu Kabir Musa
- Adanu Kekeli
- Adebara Idowu
- Adebola Oluwaseyi
- Ademuyiwa Adesoji
- Adeniran Abiodun
- Adepiti Akinfolarin
- Aderogba Adeleke Akeem
- Adesunkanmi Abdulhafiz
- Adeyeye Ademola
- Adisa Adewale
- Adjeso Theophilus Justus Kofi
- Ads Adel Mohamed
- Ads Alaa Mohamed
- Adu-Aryee Nii Armah
- Adumah Collins
- Afzal Irrum
- Agapov Mikhail
- Agarwal Gaurav
- Agarwal Ravi
- Agbeko Anita Eseenam
- Agbeno Evans Kofi
- Agbonrofo Peter
- Agboola Oluseyi
- Aggarwal Gaurav
- Aghadi Ifeanyi
- Aghtarafi Natasha
- Agrawal Amit
- Agresta Ferdinando
- Aguado Héctor J.
- Aguilera-Arevalo Maria-Lorena
- Aherne Thomas
- Ahmad Aline
- Ahmad Maleeha
- Ahmad Misbahu
- Ahmad Sarwat
- Ahmad Shahzaib
- Ahmad Shoaib
- Ahmed Hayat Tarig Abdelhafiz
- Ahmed Khalid
- Ahmed Sharwany
- Ahmed Shima
- Ahmed Usama
- Aisuodionoe-Shadrach Oseremen
- Aitken Sarah
- Ajenifuja Kayode
- Ajiya Abdulrazak
- Akeel Nouf
- Akin Emrah
- Akinajo Opeyemi
- Akinyemi Tosin
- Akrida Ioanna
- Aktokmakyan Talar Vartanoglu
- Akwaisah Ayoub
- Al Bettar Osama
- Al-Badawi Ismail A.
- Al-Juaifari Maytham
- Al-Khyatt Waleed
- Al-Mallah Abdullah
- Al-Nusairi Ahmed
- Al-Saadi Nina
- Al-Sayaghi Khaled
- Al-Shaiji Tariq
- Al-Shehari Mohammed
- Al-Touny Aiman
- Al-Touny Shimaa A.
- Aladawi Omar
- Aladna Abdallah
- Alali Mahmoud
- Alam Mahmood
- Alam Mohammed Shadrul
- Alarabi Rehab
- Alawneh Yazan
- Alayande Barnabas
- Albanese Erminia
- Albayadi Eslam
- Albdour Maram
- Alconchel Felipe
- Alderazi Amer
- Alegbeleye Bamidele
- Alekberli Tural
- Alemu Misganaw Alemu Adimass
- Alexander Philip
- Alfieri Alex
- Algahtany Khaled
- Algarni Kamal
- Alhamad Ameen
- Alhamid Mohammad
- Alharmi Rawan A. Rahman
- Alharthi Mohammed
- Alhazmi Barrag
- Ali Mohamed Shafi Mahboob
- Ali Stephen
- Alibrahim Hidar
- Aljaaly Hattan
- Aljaiuossi Anas
- Aljanadi Firas
- Aljiffry Murad
- Aljirdabi Noof
- Alkahlan Mohammed
- Alkhalifa Elmustafa
- Alkhatib Sondos
- Alkhatieb Maram
- Allan Anna
- Almarshad Felwa
- Almgla Naser
- Almhimid Ali
- Almiqlash Bushray
- Almoshantaf Mohammad Badr
- Almutairi Abdulmjeed
- Alnsour Abed Alfattah Mahmoud
- Alobied Majd
- Alomar Osama
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alonso Veronica
- Alqallaf Abdullah
- Alqaseer Asma
- Alrayes Bourhan
- Alsefri Maryam
- Alser Osaid
- Alsharif Mohammed
- Alsori Mohamed
- Altaf Abdulmalik
- Altinel Yuksel
- Altiner Saygin
- Altouny Ahmad
- Altun Demet
- Alvarez Natalia
- Alvarez-Lozada Luis Adrian
- Alvi Abdul
- Alwael Athari
- Alwash Mohammed
- Alyami Ziyad
- Alyousef Mohammed
- Alzahrani Saud
- Alzerwi Nasser
- Amin Shivang
- Amir Mohammed
- Ammar Ahmed Siddique
- Ammendola Michele
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- Andrianakis Alexandros
- Andro Christophe
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- Angelico Roberta
- Angelis Fragkiskos
- Angelou Dimitrios
- Angelou Kyveli
- Angulo Victor Pinto
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- Anjum Muhammad Ayyub
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- Anoldo Pietro
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- Arshad Muhammad
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- Glowka Tim R.
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- Goel Neha
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- Mahečić Tina Tomić
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- Martins Claudia Pinto
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- McPherson Duncan
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- Meead Adullah
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- Nacion Aeris Jane D.
- Nadi Khaldoun
- Naegele Felix
- Naga Hani
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- Nassar Mahmoud A.
- Nasser Sara
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- Ntalouka Maria P.
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- Piozzi Guglielmo Niccolò
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- Prodromidou Anastasia
- Proud David
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- Prusty Lydia
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- Pucher Philip
- Punjabi Prakash P
- Puri Ajay
- Purich Kieran
- Pérez Beatriz Gómez
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- Rokohl Alexander Christopher
- Roland Christina L
- Rolinger Jens
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- Rotunno Giuseppe
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- Rudic Milan
- Ruggiero Silvia
- Ruiz-Marín Miguel
- Russo Antonino
- Russo Giorgio Ivan
- Russo Iris Shari
- Ryalino Christopher
- Ryan James
- Ryan Éanna
- Saad Rema
- Saaid Rahmah
- Sabbagh Abdulrahman J.
- Sabella Danielle
- Sablotzki Armin
- Sacdalan Marie Dione
- Sachdev Gaurav
- Sachdeva Ashwin
- Sacras Maria Luís
- Sadia Uzma
- Saed Abdel
- Saeed Summaya
- Saeed Umar
- Safi Seyer
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- Sagnotta Andrea
- Saguil Esther
- Sahni Arun
- Sahu Mo
- Saibene Alberto Maria
- Saif Areeba
- Sakakushev Boris
- Sakhov Orazbek
- Sakr Ahmed
- Salah Rokeya
- Salamanca Omar
- Salameh Fadi-Tamas
- Salami Omotayo
- Sale Danjuma
- Saleh Ismail Ali
- Saleh Ma'Moun
- Salem Hani
- Salem Moacyr
- Salisu Ibrahim
- Salizzoni Stefano
- Sall Ibrahima
- Sallam Asser
- Salunke Pravin
- Salö Martin
- Samadov Elgun
- Saman Pradeep I.H.D.
- Samara Athina
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- Sammour Tarik
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- Sandri Giovanni Battista Levi
- Sanli Ahmet Necati
- Santini Alasdair
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- Santric Veljko
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- Sarjanoja Elise
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- Sasireka Veerasamy
- Satchithanantham Vinojan
- Satoskar Savni
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- Sayyed Raza
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- Schmitt Françoise
- Schmitz-Rixen Thomas
- Schneck Emmanuel
- Schröder Lars
- Schweitzer Donald
- Scifo Amedeo
- Scopelliti Michele
- Scott Erin
- Seah Kt Matthew
- Sebai Amine
- Seeliger Barbara
- Seenivasagam Rajkumar Kottayasamy
- Segalini Edoardo
- Segaren Neil
- Segaren Nicholas
- Seglenieks Richard
- Segura-Sampedro Juan José
- Seguya Amina
- Seidu Anwar Sadat
- Seiwerth Ingmar
- Sekulić Aleksandar
- Semple Abigail
- Sen Comert
- Senanayake Kithsiri Janakantha
- Senent-Boza Ana
- Seneviratne Sanjeewa
- Senni Carlotta
- Sensi Bruno
- Seraj Shaikh Sanjid
- Serban Andreea-Madalina
- Serenari Matteo
- Serra Margherita
- Serra Marta Lopes
- Seshadri Ramakrishnan Ayloor
- Sethi Aman
- Seyfried Steffen
- Seyi-Olajide Justina
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- Shaban Naseebah
- Shaddad Ebrahim
- Shaerf Daniel
- Shah Faaiz Ali
- Shah Hemina
- Shah Jaffer
- Shah Karishma
- Shah Pritik A
- Shah Vinay
- Shaikh Shafaque
- Shalaby Mostafa
- Shalhoub Joseph
- Shamim Shahzad
- Sharma Naveen
- Sharma Neil
- Sharma Rahul Deo
- Sharma Shilpa
- Sharpin Claire
- Sheen Jonathon
- Shehata Sherif
- Shehta Ahmed
- Sheik Shahila
- Sheikh Eman
- Shekleton Florence
- Shelat Vishal
- Shelmerdine Lauren
- Sherif Ahmed Elshawadfy
- Shiban Ehab
- Shiota Masaki
- Shirazi Ahmed
- Shiwani Haaris
- Shmukler Daniel
- Shokor Muntaser Abu
- Sholadoye Tunde T.
- Shoukrie Shoukrie I. M.
- Shrestha Rashmit
- Siboe Mark
- Sica Giuseppe
- Siddig Esra
- Siddiqui M. Tayyab
- Sidiropoulos Theodoros
- Sievers Denise
- Sigamoney Kohila
- Silvestri Vania
- Simoes Joana
- Simon Natalie
- Simoncini Tommaso
- Simões Joana Filipa Ferreira
- Singer Georg
- Singh Abhinav
- Singh Baljit
- Singh Kathryn
- Singh Rajdeep
- Singh Tanveer
- Sinnerton Robert
- Siragusa Leandro
- Sivaprakasam Rajesh
- Skipworth Richard Je
- Slavchev Mihail
- Sleem Adham
- Smati Ismail
- Smelt Jeremy
- Smith A.
- Smolle-Juettner Freyja-Maria
- Sodhai Vivek
- Sofi Khalid
- Sohrabi Catrin
- Soibiharry Adaiah
- Sokolov Manol
- Solaini Leonardo
- Sole Oriol Martin
- Sole-Sedeno Josep M.
- Soljic Martina
- Solli Piergiorgio
- Soon Wai Cheong
- Sorbi Flavia
- Sotiropoulou Maria
- Sotudeh Mohadeseh
- Souadka Amine
- Soucheiron Maria Coronas
- Soytas Mustafa
- Sozzi Giulio
- Sparavigna Marco
- Spartalis Michael
- Spellar Kayleigh
- Spiers Harry V. M.
- Spina Alfio
- Spriano Giuseppe
- Squiers John
- Stabler Robert
- Stamatakis Emmanouil
- Stamatis Konstantinos
- Starr Nichole
- Stather Philip
- Stevens Sean
- Stevenson Andrew
- Stewart Grant D.
- Stijns Jasper
- Stogowski Piotr Tomasz
- Stoleriu Mircea Gabriel
- Stoyanov Vladislav
- Street John
- Strotmann Johanna Josefine
- Stroumpoulis Konstantinos
- Su Yu-Xiong
- Suarez Sara Busto
- Subramani Yamini
- Subramaniam Sentilnathan
- Sue-Chue-Lam Colin
- Suer Muhammed Salih
- Sulaiman Bilal
- Sultania Mahesh
- Sundarraju Shalini
- Sungurtekin Hulya
- Suresh Sreelakshmi
- Surya Ilham Utama
- Swed Sarya
- Syllaios Athanasios
- Symeonidis Dimitrios
- Szabómihályová Katarína
- Szakmany Tamas
- Szatmary Peter
- Sztipits Tamás
- Szyluk Karol
- Sá-Marta Eduarda
- Sánchez Alberto Cabañero
- Sánchez Rosa
- Sánchez-Guillén Luis
- Süleyman Marlen
- Tadic Boris
- Taha Anas
- Taha-Mehlitz Stephanie
- Tailor Bhavesh
- Taj Eldeen Samaher Taj Eldeen Hassan
- Takeda Flavio Roberto
- Takkenberg Marijn
- Talat Nabila
- Tallon-Aguilar Luis
- Talwar Rishi
- Tamayo Beatriz Villota
- Tamburello Sara
- Tamini Nicolò
- Tammo Ömer
- Tamoos Khalil
- Tampaki Ekaterini Christina
- Tampakis Athanasios
- Tan Chih Ying
- Tan Shawn Jia Hwang
- Tanal Mert
- Tanas Yousef
- Tang Alethea
- Tang Yita
- Tani Sobhana Iftekhar
- Tantraworasin Apichat
- Tantri Aida Rosita
- Tapia-Herrero Ana-María
- Tarek Ahmed
- Tariq Aiman
- Tarle Marko
- Tarsitano Achille
- Tartaglia Dario
- Tartaglia Nicola
- Tashkandi Wail
- Taskiran Cagatay
- Tatar Cihad
- Tatsis Dimitris
- Tawalbeh Ra'Fat
- Tawiah Augustine
- Tebha Sameer
- Techapongsatorn Suphakarn
- Teixeira Pedro
- Tejero-Pintor Francisco J.
- Tellez Karla Susana Martin
- Tellez Luis Garcia-Sancho
- Thaha Mohamed Adhnan
- Thakar Sumit
- Thaw May Htoo
- Theivendran Kanthan
- Thekkinkattil Dinesh
- Theochari Nikoletta
- Theodoropoulos George
- Theophilidou Elena
- Thereska Dariel
- Thiruchandran Gajendiran
- Thomakos Nikolaos
- Thomas Bradley
- Thomas Jerin Jose
- Thuduvage Vasanthika
- Thumbadoo Ruben
- Tian Sarah
- Tidjane Anisse
- Tirloni Luca
- Toia Francesca
- Tokidis Evripidis
- Tokocin Merve
- Tolani Musliu Adetola
- Toma Elena Adelina
- Tomasicchio Giovanni
- Tomlinson James
- Tonini Valeria
- Torre Beatrice
- Torregrosa Cristina
- Torun Bahar Canbay
- Tottman R.
- Tousidonis Manuel
- Trabulsi Nora
- Tranca Sebastian
- Trebol Jacobo
- Trejo-Avila Mario
- Triantafyllou Alexandra
- Triantafyllou Tania
- Trifunovski Aleksandar
- Tripathi Manjul
- Tripathi Prashant
- Tripathy Sujit
- Trivik-Barrientos Felipe
- Trostchansky Ivan
- Trulson Alexander
- Trungu Sokol
- Truss Adam
- Tsakiridis Ioannis
- Tsakiridis Nikolaos
- Tsiantoula Paraskevi
- Tsironis Dimitrios
- Tsolakidis Alexandros
- Tsoulfas Georgios
- Tucker Olga
- Tuech Jean Jacques
- Turan Alparslan
- Turi Stefano
- Turna Akif
- Turrado-Rodriguez Victor
- Turri Giulia
- Tutino Roberta
- Tuyishime Eugene
- Tzelves Lazaros
- Tzima Ioanna
- Tzimas George
- Ubiali Paolo
- Ubom Akaninyene Eseme
- Ugwu Aloy Okechukwu
- Ugwu Ebere
- Ugwu Ifeanyichukwu
- Ul Huda Maria Noor
- Ulas Ali Bilal
- Uldry Emilie
- Ulgur Hanife Seyda
- Ulkucu Attila
- Ulman Elif Akbas
- Ulman Hilmican
- Ulutaş Mehmet Eşref
- Underwood Kirk
- Unsworth Richard
- Uprak Tevfik Kivilcim
- Urriza Pablo Vallés
- Usman Muhammad
- Usman Mustapha Ibrahim
- Vaassen Lauretta
- Vaccara Vincenzo La
- Vagena Xanthoula
- Vagge Aldo
- Vailas Michail
- Valadez Andrea Estefania Cueto
- Valadez Tania Abigail Cueto
- Valanci Sofia
- Valdespino Cristina Puentes
- Valeanu Liana
- Valioulis Ioannis
- Valladares Sergio Chávez
- Vallve-Bernal Marc
- Van Acker Jill
- Van Den Eynde Jef
- Van Goor Harry
- Van Vliet Helen
- Van Wyk Naomi Natasha
- Vanni Camilla
- Vas Aurelia
- Vasarhelyi Edward
- Vaschetti Roberto
- Vassiliu Panteleimon
- Vatansever Dogan
- Vatish Jamie
- Vaughan-Shaw Peter G.
- Vaysburg Dennis
- Veglia Antonella
- Velten Markus
- Velázquez Maria Jose Martinez
- Venkatappa Sunil Kumar
- Venketeswaran Meenakshi
- Venskutonis Donatas
- Verbic Milena Senica
- Verdi Daunia
- Vergara-Fernandez Omar
- Verhoeff Kevin
- Veroux Massimiliano
- Verras Georgios-Ioannis
- Verre Luigi
- Vida Lucian
- Vidya Raghavan
- Viglietta Edoardo
- Vijay Vardhini
- Vijgen Guy
- Vilaró Blanca Capdevila
- Villanueva Julio
- Vilz Tim O.
- Vincent Elizabeth
- Vinci Danilo
- Viola Simona
- Violante Tommaso
- Vishnoi Jeewan Ram
- Vissapragada Ravi
- Vivancos Laura Guillamon
- Vives Josep Maria Muñoz
- Vizzielli Giuseppe
- Vohra Lubna
- Vokshi Ismail
- Vosinakis Christos
- Vásquez Javier Alberto Gutiérrez
- Vázquez Gil
- Vázquez Irene Ortega
- Vǎcǎraşu Andrei Bogdan
- Wade Ryckie
- Wafi Omar
- Wagner Gabriela
- Wallis Christopher
- Wanjara Samuel
- Waqar Shahzad Hussain
- Warden Claire
- Warner Christian
- Wasim D.
- Wason Shaun
- Wasserman Isaac
- Watcyn-Jones Tom
- Waterson Ben
- Watson David
- Watson Matthew
- Weber Clemens
- Wheatstone P.
- Wheeler James
- Wheldon Luke
- White Michelle
- White Stuart
- White William
- Wickramasinghe Dakshitha
- Widmer Lukas Werner
- Wiedemann Dominik
- Wiesinger Clemens Georg
- Wijekoon Naveen
- Wijenayake Wasantha
- Wijeyaratne Manuk
- Wijeysundera Duminda
- Wiles Matthew
- Wilkin Richard
- Wilkins Alex
- Wilkins James
- William Tinka George
- Williams Omolara Modupe
- Williams Shekinah
- Windsor John
- Winnand Philipp
- Wittmann Maria
- Wolde Amanuel
- Wolfenden John W. D.
- Wong Benjamin Ngie Xiong
- Wong Enoch
- Wong Evan G.
- Wong George Kwok Chu
- Wong Ho Ying Flora
- Wong Kai Yuen
- Wormald Justin
- Wright Deborah
- Wright Joshua
- Wu Fiona
- Wurm Markus
- Xenaki Sofia
- Yadev Ip
- Yahaya Ahmad Shuib
- Yakubu Mustapha
- Yang Wah
- Yanik Özge
- Yanowsky-Reyes Guillermo
- Yassin Abubaker
- Yates Elizabeth
- Yebes Alvaro
- Yenli Edwin Mwintiereh Ta-Ang
- Yeoh Tien
- Yeung Justin
- Yiallourou Anneza
- Yigit Banu
- Yildirim Asif
- Yim Guang
- Yiu Andrew
- Yonekura Hiroshi
- Yotsov Tsanko
- Younis Muhammad Umar
- Yunus Alif
- Yusefi Hossein
- Zabaleta Jon
- Zabkiewicz Catheriner
- Zaccaria Giulia
- Zacharia Bincy
- Zafar Syed Nabeel
- Zago Mauro
- Zaheen Zakia
- Zahid Zahra
- Zaimis Tilemachos
- Zakaria Andee Dzulkarnaen
- Zambon Martina
- Zamora Lindsey
- Zampogna Biagio
- Zancana Giuseppa
- Zani Augusto
- Zanin Luca
- Zanini Nicola
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarif Pierre
- Zaránd Attila
- Zehnder Philipp
- Zenger Serkan
- Zenha Horácio
- Zhu Michael Z. L.
- Ziemann Sebastian
- Zimak Danijela Mrazovac
- Zimak Zoran
- Zivkovic Dragana
- Zizzo Maurizio
- Zucker Benjamin
- Zwain Yasir
- Zyskowski Michael
- Ávila Clara Castro
- Älgå Andreas
- Çakici Mehmet Çaǧlar
- Çelik Enes
- Çelik Meryem Nur
- Özçay Necdet
- Şevik Hüsnü
- Šantak Goran
- Šimko Kristián
- Žatecký Jan
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2023
- Field of study
Abstract
Background
Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres.
Methods
This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries.
Results
In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia.
Conclusion
This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries
Functional muscle recovery with nanoparticle-directed M2 macrophage polarization in mice
- Publication venue
- 'Proceedings of the National Academy of Sciences'
- Publication date
- Field of study
Local Delivery of VEGF and SDF Enhances Endothelial Progenitor Cell Recruitment and Resultant Recovery from Ischemia
- Author
- Publication venue
- 'Mary Ann Liebert Inc'
- Publication date
- Field of study
Exosomes Derived from Squamous Head and Neck Cancer Promote Cell Survival after Ionizing Radiation
- Author
- A Al-Mayah
- A Kraemer
- A Kraemer
- AH Al-Mayah
- BD Lehmann
- C Battke
- C Corcoran
- C Théry
- Carsten Peters
- DJ Adelstein
- G Raposo
- H Peinado
- H Valadi
- H Xiao
- J Wang
- JE Park
- K Al-Nedawi
- KK Jella
- Klaudia Winkler
- L Yang
- Lisa Mutschelknaus
- M Chiba
- M Eldh
- M Hazawa
- M Mineo
- M Wysoczynski
- Michael John Atkinson
- OG de Jong
- Pierre Busson
- R Crescitelli
- Ramesh Yentrapalli
- S Dutta
- S Raimondo
- Simone Moertl
- Theresa Heider
- TL King
- V Ciravolo
- VB O'Leary
- WT Arscott
- WX Chen
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- Field of study
Prevalence, years lived with disability, and trends in anaemia burden by severity and cause, 1990–2021: findings from the Global Burden of Disease Study 2021
- Author
- Aali Amirali
- Abate Kalkidan Hassen
- Abd-Elsalam Sherief
- Abdurehman Ame Mehadi
- Abebe Getachew
- Abidi Hassan
- Aboagye Richard Gyan
- Abolhassani Hassan
- Aboye Girma Beressa Aboye
- Abtew Yonas Derso
- Accrombessi Manfred Mario Kokou
- Adane Denberu Eshetie Adane
- Adane Tigist Demssew
- Addo Isaac Yeboah
- Adesina Miracle Ayomikun
- Adeyinka Daniel Adedayo
- Adnani Qorinah Estiningtyas Sakilah
- Afzal Muhammad Sohail
- Afzal Saira
- Agustina Rina
- Ahinkorah Bright Opoku
- Ahmad Aqeel
- Ahmad Sajjad
- Ahmadi Sepideh
- Ahmed Rashid Tarik
- Ahmed Ayman
- Aiman Wajeeha
- Ajami Marjan
- Akbarialiabad Hossein
- Al-Aly Ziyad
- Al-Raddadi Rajaa M
- Al-Rifai Rami H
- Alahdab Fares
- Alam Nazmul
- Alemayehu Astawus
- Alhassan Robert Kaba
- Ali Muhammad Ashar
- Almustanyir Sami
- Altirkawi Khalid A
- Alvand Saba
- Alvis-Guzman Nelson
- Amer Yasser Sami Abdel Dayem
- Ameyaw Edward Kwabena
- Amu Hubert
- Anagaw Tadele Fentabil
- Ancuceanu Robert
- Anoushirvani Ali Arash
- Antwi Maxwell Hubert
- Anvari Davood
- Arabloo Jalal
- Aravkin Aleksandr Y
- Ariffin Hany
- Aripov Timur
- Arja Asrat
- Arndt Michael Benjamin
- Arulappan Judie
- Aruleba Raphael Taiwo
- Ashraf Tahira
- Asresie Melash Belachew
- Athari Seyyed Shamsadin
- Atlaw Daniel
- Aujayeb Avinash
- Awoke Andargie Abate
- Awoke Mamaru Ayenew
- Azadnajafabad Sina
- Azangou-Khyavy Mohammadreza
- B Darshan B
- Badawi Alaa
- Badiye Ashish D
- Baghcheghi Nayereh
- Bagheri Nasser
- Bagherieh Sara
- Baig Atif Amin
- Banach Maciej
- Banik Palash Chandra
- Bantie Abere Tilahun
- Barr Ronald D
- Barrow Amadou
- Bashiri Azadeh
- Basu Saurav
- Batiha Abdul-Monim Mohammad
- Begum Tahmina
- Belete Melaku Ashagrie
- Belo Luis
- Bensenor Isabela M
- Berhie Alemshet Yirga
- Bhagavathula Akshaya Srikanth
- Bhardwaj Nikha
- Bhardwaj Pankaj
- Bhat Ajay Nagesh
- Bhutta Zulfiqar A
- Bikbov Boris
- Billah Sk Masum
- Birara Setognal
- Bishai Jessica Devin
- Bitaraf Saeid
- Boloor Archith
- Botelho João Silva Botelho
- Burkart Katrin
- Calina Daniela
- Cembranel Francieli
- Cercy Kelly M
- Chakraborty Promit Ananyo
- Chanie Gashaw Sisay
- Chattu Vijay Kumar
- Chen Catherine S
- Chien Ju-Huei
- Chukwu Isaac Sunday
- Chung Eunice
- Criqui Michael H
- Cruz-Martins Natália
- Dadras Omid
- Dagnew Gizachew Worku
- Dai Xiaochen
- Danawi Hadi A
- Dandona Lalit
- Dandona Rakhi
- Darwesh Aso Mohammad
- Das Jai K
- Das Saswati
- De la Cruz-Góngora Vanessa
- Demisse Fitsum Wolde
- Demissie Solomon
- Demsie Desalegn Getnet
- Desai Hardik Dineshbhai
- Desalegn Markos Desalegn
- Dessalegn Fikadu Nugusu
- Dessie Gashaw
- Dharmaratne Samath Dhamminda
- Dhimal Meghnath
- Dhingra Sameer
- Diaz Daniel
- Didehdar Mojtaba
- Dirac M Ashworth
- Diress Mengistie
- Doaei Saeid
- Dodangeh Milad
- Doku Paul Narh
- Dongarwar Deepa
- Dora Bezabih Terefe
- Dsouza Haneil Larson
- Edinur Hisham Atan
- Ekholuenetale Michael
- El-Huneidi Waseem
- Elagali Ahmed Elabbas Mustafa
- Elbahnasawy Mostafa Ahmed
- Elbarazi Iffat
- ElGohary Ghada Metwally Tawfik
- Elhadi Muhammed
- Elmonem Mohamed A
- Enyew Daniel Berhanie
- Eshetu Habitu Birhan
- Ewald Samuel B
- Ezzeddini Rana
- Fagbamigbe Adeniyi Francis
- Fasanmi Abidemi Omolara
- Fatehizadeh Ali
- Fekadu Ginenus
- Feyisa Bikila Regassa
- Fischer Florian
- Fitzgerald Ryan
- Foroutan Masoud
- Fowobaje Kayode Raphael
- Fuller Kia
- Gadanya Muktar A
- Gaidhane Abhay Motiramji
- Gaihre Santosh
- Gaipov Abduzhappar
- Galali Yaseen
- Galehdar Nasrin
- Gardner William M
- Garg Priyanka
- Garg Tushar
- Gebremariam Yosef Haile
- Gebremedhin Ketema Bizuwork
- Gebremichael Berhe
- Gela Yibeltal Yismaw
- Gerema Urge
- Getacher Lemma
- Ghaffari Kazem
- Ghafourifard Mansour
- Ghamari Seyyed-Hadi
- Ghasemi Nour Mohammad
- Ghashghaee Ahmad
- Gholamalizadeh Maryam
- Ghozy Sherief
- Gizaw Abraham Tamirat T
- Glasbey James C
- Golechha Mahaveer
- Goleij Pouya
- Golitaleb Mohamad
- Goulart Alessandra C
- Goyomsa Girma Garedew
- Guadie Habtamu Alganeh
- Gubari Mohammed Ibrahim Mohialdeen
- Gudisa Zewdie
- Gunawardane Damitha Asanga
- Gupta Rahul
- Gupta Rajat Das
- Gupta Sapna
- Gupta Vivek Kumar
- Guta Alemu
- Habibzadeh Parham
- Hagins Hailey
- Hamidi Samer
- Handal Alexis J
- Hanif Asif
- Hannan Md Abdul
- Harapan Harapan
- Harorani Mehdi
- Hasaballah Ahmed I
- Hasan Md Mehedi
- Hasani Hamidreza
- Hassankhani Hadi
- Hassen Mohammed Bheser
- Hay Simon I
- Hayat Khezar
- Heidari Golnaz
- Hennessy Conor
- Hess Sonja Y
- Heyi Demisu Zenbaba
- Hezam Kamal
- Hiraike Yuta
- Holla Ramesh
- Hossain Sheikh Jamal
- Hosseini Kaveh
- Hosseini Mohammad-Salar
- Hosseinzadeh Mehdi
- Hostiuc Mihaela
- Hostiuc Sorin
- Huang Junjie
- Hussain Salman
- Hussien Foziya Mohammed
- Ibitoye Segun Emmanuel
- Ilesanmi Olayinka Stephen
- Ilic Irena M
- Immurana Mustapha
- Inbaraj Leeberk Raja
- Islam Sheikh Mohammed Shariful
- Ismail Nahlah Elkudssiah
- J Linda Merin
- Jamshidi Elham
- Janodia Manthan Dilipkumar
- Jayarajah Umesh
- Jayaram Shubha
- Jebai Rime
- Jemal Bedru
- Jeyakumar Angeline
- Jha Ravi Prakash
- Jonas Jost B
- Joseph Nitin
- Jozwiak Jacek Jerzy
- Kabir Ali
- Kalankesh Laleh R
- Kalhor Rohollah
- Kamal Vineet Kumar
- Kandel Himal
- Kanko Tesfaye K
- Karaye Ibraheem M
- Kashoo Faizan Zaffar
- Kassebaum Nicholas J
- Katoto Patrick DMC
- Kauppila Joonas H
- Kaur Harkiran
- Kayode Gbenga A
- Kebede Adera Debella
- Keshri Vikash Ranjan
- Keykhaei Mohammad
- Khader Yousef Saleh
- Khajuria Himanshu
- Khalid Nauman
- Khammarnia Mohammad
- Khan Imteyaz A
- Khan Moien AB
- Khatab Khaled
- Khazaei Zaher
- Khubchandani Jagdish
- Kim Yun Jin
- Kimokoti Ruth W
- Kisa Sezer
- Kompani Farzad
- Kosen Soewarta
- Koulmane Laxminarayana Sindhura Lakshmi
- Krishan Kewal
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- Kumar G Anil
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- Lal Dharmesh Kumar
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- Latief Kamaluddin
- Laxmaiah Avula
- Ledda Caterina
- Lee Sang-woong
- Legesse Samson Mideksa
- Lim Stephen S
- Liu Xuefeng
- Lorenzovici László
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- Mahajan Preetam Bhalchandra
- Mahjoub Soleiman
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- Masoudi Sahar
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- Niazi Robina Khan
- Noori Maryam
- Nowroozi Ali
- Nurrika Dieta
- Nuruzzaman Khan M
- Nzoputam Ogochukwu Janet
- Oancea Bogdan
- Obaidur Rahman Md
- Obsa Mohammed Mohammed Suleiman Suleiman
- Odhiambo Julius Nyerere
- Ogunsakin Ropo Ebenezer
- Okati-Aliabad Hassan
- Okonji Osaretin Christabel
- Oladunjoye Adeolu Olufunso
- Oladunjoye Olubunmi Omotola
- Olagunju Andrew T
- Olufadewa Isaac Iyinoluwa
- Omar Bali Ahmed
- Omonisi Abidemi E Emmanuel
- Ortiz Alberto
- Owolabi Mayowa O
- Padubidri Jagadish Rao
- Pakzad Reza
- Palicz Tamás
- Pandey Anamika
- Pandya Apurva Kumar
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- Pereira Gavin
- Perico Norberto
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- Perumal Nandita
- Perumalsamy Navaraj
- Petcu Ionela-Roxana
- Pickering Brandon V
- Piracha Zahra Zahid
- Pollok Richard Charles G
- Pradhan Pranil Man Singh
- Prashant Akila
- Qattea Ibrahim
- Quazi Syed Zahiruddin
- Rahim Fakher
- Rahimi Mehran
- Rahman Azizur
- Rahman Mohammad Hifz Ur
- Rahman Mosiur
- Rahmani Amir Masoud
- Rahmani Shayan
- Rai Rajesh Kumar
- Raimondo Ivano
- Rajaa Sathish
- Ram Pradhum
- Rana Juwel
- Ranjha Muhammad Modassar Ali Nawaz
- Rao Chythra R
- Rao Sowmya J
- Rashedi Sina
- Rashidi Mohammad-Mahdi
- Rawaf Salman
- Rawal Lal
- Raza Rabail Zehra
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- Redwan Elrashdy Moustafa Mohamed
- Remuzzi Giuseppe
- Rezaei Maryam
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- Roever Leonardo
- Roshandel Gholamreza
- Roy Bedanta
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- Saad Aly M A
- Sabour Siamak
- Saddik Basema
- Sadeghi Malihe
- Sadeghian Saeid
- Saeed Umar
- Sahebkar Amirhossein
- Sahoo Harihar
- Salem Marwa Rashad
- Samy Abdallah M
- Sankararaman Senthilkumar
- Santoro Rocco
- Santos Itamar S
- Satpathy Maheswar
- Saya Ganesh Kumar
- Seboka Binyam Tariku
- Senbeta Anbissa Muleta
- Senthilkumaran Subramanian
- Seylani Allen
- Shafeghat Melika
- Shah Pritik A
- Shaikh Masood Ali
- Shanawaz Mohd
- Shannawaz Mohammed
- Sharew Mequannent Melaku Sharew
- Sharma Purva
- Sheikhi Rahim Ali
- Shenoy Suchitra M
- Shetty Adithi
- Shetty B Suresh Kumar
- Shetty Jeevan K
- Shetty Pavanchand H
- Shin Jae Il
- Shivalli Siddharudha
- Shivarov Velizar
- Shobeiri Parnian
- Shorofi Seyed Afshin
- Sikder Mustafa Kamal
- Sima Ali Reza
- Simegn Wudneh
- Singh Jasvinder A
- Singh Narinder Pal
- Singh Paramdeep
- Singh Surjit
- Siraj Md Shahjahan
- Sisay Yordanos
- Skryabina Anna Aleksandrovna
- Solomon Yonatan
- Song Yi
- Sorensen Reed J D
- Stanaway Jeffrey D
- Suchdev Parminder S
- Sufiyan Mu'awiyyah Babale
- Sultana Saima
- Szeto Mindy D
- Tabaeian Seidamir Pasha
- Tahamtan Alireza
- Taheri Soodejani Moslem
- Taheri Majid
- Tamir Zemenu
- Tan Ker-Kan
- Tariqujjaman Md
- Tarkang Elvis Enowbeyang
- Tat Nathan Y
- Taylor Heather Jean
- Tefera Yibekal Manaye
- Temsah Mohamad-Hani
- Thapar Rekha
- Thiyagarajan Arulmani
- Ticoalu Jansje Henny Vera
- Tigabu Bereket M
- Tiyuri Amir
- Tobe-Gai Ruoyan
- Tovani-Palone Marcos Roberto
- Tran Mai Thi Ngoc
- Tusa Biruk Shalmeno
- Ullah Irfan
- Umer Abdurezak Adem
- Unnikrishnan Bhaskaran
- Vacante Marco
- Valadan Tahbaz Sahel
- Valdez Pascual R
- Vart Priya
- Varthya Shoban Babu
- Vaziri Siavash
- Verma Madhur verma
- Veroux Massimiliano
- Vervoort Dominique
- Vilchis-Tella Victor M
- Vu Linh Gia
- Wagaye Birhanu
- Weldegebreal Fitsum
- Wickramasinghe Nuwan Darshana
- Woldemariam Melat
- Wonde Tewodros Eshete
- Wubetie Gedif Ashebir
- Xu Xiaoyue
- Yari Kheirollah
- Yazdanpanah Fereshteh
- Yehualashet Sisay Shewasinad
- Yigit Arzu
- Yisihak Eshetu
- Yiğit Vahit
- Yon Dong Keon
- Yonemoto Naohiro
- Young Melissa F
- Yu Chuanhua
- Yunusa Ismaeel
- Zahir Mazyar
- Zaki Leila
- Zaman Burhan Abdullah
- Zamora Nelson
- Zare Iman
- Zareshahrabadi Zahra
- Zenebe Getachew Assefa
- Zhang Zhi-Jiang
- Zheng Peng
- Zoeckler Leo Zucker
- Zoladl Mohammad
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background: Anaemia is a major health problem worldwide. Global estimates of anaemia burden are crucial for developing appropriate interventions to meet current international targets for disease mitigation. We describe the prevalence, years lived with disability, and trends of anaemia and its underlying causes in 204 countries and territories. Methods: We estimated population-level distributions of haemoglobin concentration by age and sex for each location from 1990 to 2021. We then calculated anaemia burden by severity and associated years lived with disability (YLDs). With data on prevalence of the causes of anaemia and associated cause-specific shifts in haemoglobin concentrations, we modelled the proportion of anaemia attributed to 37 underlying causes for all locations, years, and demographics in the Global Burden of Disease Study 2021. Findings: In 2021, the global prevalence of anaemia across all ages was 24·3% (95% uncertainty interval [UI] 23·9–24·7), corresponding to 1·92 billion (1·89–1·95) prevalent cases, compared with a prevalence of 28·2% (27·8–28·5) and 1·50 billion (1·48–1·52) prevalent cases in 1990. Large variations were observed in anaemia burden by age, sex, and geography, with children younger than 5 years, women, and countries in sub-Saharan Africa and south Asia being particularly affected. Anaemia caused 52·0 million (35·1–75·1) YLDs in 2021, and the YLD rate due to anaemia declined with increasing Socio-demographic Index. The most common causes of anaemia YLDs in 2021 were dietary iron deficiency (cause-specific anaemia YLD rate per 100 000 population: 422·4 [95% UI 286·1–612·9]), haemoglobinopathies and haemolytic anaemias (89·0 [58·2–123·7]), and other neglected tropical diseases (36·3 [24·4–52·8]), collectively accounting for 84·7% (84·1–85·2) of anaemia YLDs. Interpretation: Anaemia remains a substantial global health challenge, with persistent disparities according to age, sex, and geography. Estimates of cause-specific anaemia burden can be used to design locally relevant health interventions aimed at improving anaemia management and prevention. Funding: Bill & Melinda Gates Foundation
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
- Author
- Aadam Olalekan Bodunrin (18346572)
- Aanuoluwa James Salemcity (18803035)
- Aaron J Cohen (8673585)
- Abbas Mosapour (9154247)
- Abdallah HA Abd Al Magied (18802573)
- Abdallah M Samy (8383428)
- Abdallah Y Naser (18347016)
- Abdelghani Tbakhi (12229742)
- Abdoljalal Marjani (18346929)
- Abdorrahim Absalan (18578551)
- Abdul Hafiz (89029)
- Abdul Wadood Wadood (18803098)
- Abdul Waris (712246)
- Abdulaal Chitheer (8673570)
- Abdulahi Opejin Opejin (18802957)
- Abdulaziz T Bako (18346515)
- Abdulfatai Aremu (9536881)
- Abdulqadir J Nashwan (17991280)
- Abera M Mersha (12150669)
- Abhinav Singh (358909)
- Abhishek Anil (17937800)
- Abhishek Shankar (18207631)
- Abid Ali (3123210)
- Abida Sultana (8147670)
- Abiola Ogunkoya (17255770)
- Abu Sayeed (195793)
- Abubakar Ibrahim Jatau (7623503)
- Abzal Zhumagaliuly (17612982)
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- Publication venue
- Publication date
- 16/05/2024
- Field of study
BackgroundFuture trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternative scenarios assessing disease burden trajectories if selected sets of risk factors were eliminated from current levels by 2050.MethodsUsing forecasts of major drivers of health such as the Socio-demographic Index (SDI; a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. All analyses were done at the cause-specific level so that only risk factors deemed causal by the GBD comparative risk assessment influenced future trajectories of mortality for each disease. Cause-specific mortality was modelled using mixed-effects models with SDI and time as the main covariates, and the combined impact of causal risk factors as an offset in the model. At the all-cause mortality level, we captured unexplained variation by modelling residuals with an autoregressive integrated moving average model with drift attenuation. These all-cause forecasts constrained the cause-specific forecasts at successively deeper levels of the GBD cause hierarchy using cascading mortality models, thus ensuring a robust estimate of cause-specific mortality. For non-fatal measures (eg, low back pain), incidence and prevalence were forecasted from mixed-effects models with SDI as the main covariate, and YLDs were computed from the resulting prevalence forecasts and average disability weights from GBD. Alternative future scenarios were constructed by replacing appropriate reference trajectories for risk factors with hypothetical trajectories of gradual elimination of risk factor exposure from current levels to 2050. The scenarios were constructed from various sets of risk factors: environmental risks (Safer Environment scenario), risks associated with communicable, maternal, neonatal, and nutritional diseases (CMNNs; Improved Childhood Nutrition and Vaccination scenario), risks associated with major non-communicable diseases (NCDs; Improved Behavioural and Metabolic Risks scenario), and the combined effects of these three scenarios. Using the Shared Socioeconomic Pathways climate scenarios SSP2-4.5 as reference and SSP1-1.9 as an optimistic alternative in the Safer Environment scenario, we accounted for climate change impact on health by using the most recent Intergovernmental Panel on Climate Change temperature forecasts and published trajectories of ambient air pollution for the same two scenarios. Life expectancy and healthy life expectancy were computed using standard methods. The forecasting framework includes computing the age-sex-specific future population for each location and separately for each scenario. 95% uncertainty intervals (UIs) for each individual future estimate were derived from the 2·5th and 97·5th percentiles of distributions generated from propagating 500 draws through the multistage computational pipeline.FindingsIn the reference scenario forecast, global and super-regional life expectancy increased from 2022 to 2050, but improvement was at a slower pace than in the three decades preceding the COVID-19 pandemic (beginning in 2020). Gains in future life expectancy were forecasted to be greatest in super-regions with comparatively low life expectancies (such as sub-Saharan Africa) compared with super-regions with higher life expectancies (such as the high-income super-region), leading to a trend towards convergence in life expectancy across locations between now and 2050. At the super-region level, forecasted healthy life expectancy patterns were similar to those of life expectancies. Forecasts for the reference scenario found that health will improve in the coming decades, with all-cause age-standardised DALY rates decreasing in every GBD super-region. The total DALY burden measured in counts, however, will increase in every super-region, largely a function of population ageing and growth. We also forecasted that both DALY counts and age-standardised DALY rates will continue to shift from CMNNs to NCDs, with the most pronounced shifts occurring in sub-Saharan Africa (60·1% [95% UI 56·8–63·1] of DALYs were from CMNNs in 2022 compared with 35·8% [31·0–45·0] in 2050) and south Asia (31·7% [29·2–34·1] to 15·5% [13·7–17·5]). This shift is reflected in the leading global causes of DALYs, with the top four causes in 2050 being ischaemic heart disease, stroke, diabetes, and chronic obstructive pulmonary disease, compared with 2022, with ischaemic heart disease, neonatal disorders, stroke, and lower respiratory infections at the top. The global proportion of DALYs due to YLDs likewise increased from 33·8% (27·4–40·3) to 41·1% (33·9–48·1) from 2022 to 2050, demonstrating an important shift in overall disease burden towards morbidity and away from premature death. The largest shift of this kind was forecasted for sub-Saharan Africa, from 20·1% (15·6–25·3) of DALYs due to YLDs in 2022 to 35·6% (26·5–43·0) in 2050. In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. The Safer Environment scenario had its largest decrease in sub-Saharan Africa (5·2% [3·5–6·8]), the Improved Behavioural and Metabolic Risks scenario in north Africa and the Middle East (23·2% [20·2–26·5]), and the Improved Nutrition and Vaccination scenario in sub-Saharan Africa (2·0% [–0·6 to 3·6]).InterpretationGlobally, life expectancy and age-standardised disease burden were forecasted to improve between 2022 and 2050, with the majority of the burden continuing to shift from CMNNs to NCDs. That said, continued progress on reducing the CMNN disease burden will be dependent on maintaining investment in and policy emphasis on CMNN disease prevention and treatment. Mostly due to growth and ageing of populations, the number of deaths and DALYs due to all causes combined will generally increase. By constructing alternative future scenarios wherein certain risk exposures are eliminated by 2050, we have shown that opportunities exist to substantially improve health outcomes in the future through concerted efforts to prevent exposure to well established risk factors and to expand access to key health interventions.FundingBill & Melinda Gates Foundation.</p
Analysis of Outcomes in Ischemic vs Nonischemic Cardiomyopathy in Patients With Atrial Fibrillation A Report From the GARFIELD-AF Registry
- Author
- A'Court Christine
- Abdel-Qader Muwafeg
- Abe Masahiko
- Abe Masatake
- Abe Mitsunori
- Abe Sumihisa
- Abe Yukihiko
- Abhayaratna Walter
- Accogli Michele
- Adachi Susumu
- Adachi Toru
- Adak Dhriti
- Adam Matthew
- Adriaansen Henk
- Aegerter Emanuel
- Ageta Masato
- Aggarwala Anil
- Agnelli Giancarlo
- AgnieszkaMetzgier-Gumiela AgnieszkaMetzgier-Gumiela
- Ahlmark Hakan
- Ahmad Kamran
- Ahmad Shahid
- Ahmed Fayzal
- Ahn Jung Joo
- Akers Lori
- Akiyama Masahiro
- Al Mahmeed Wael
- Al-Khalili Faris
- Alberts Mark
- Alborough Elizabeth
- Aldegather Jehad
- Aleksandrova Elena
- Alexandre Almeida Carlos
- Ali Amar
- Ali Gholam
- Alia Pilar Montero
- Allasia Bartolomeo
- Alonso Carmela
- Alonso Concepcion
- Altun Armagan
- Alunni Massimo
- Alvarez Garcia Pere
- Alvarez Douglas
- Alvarez Miguel
- Alzogaray Maria Fernanda
- Amarenco Pierre
- Amaro Marisol
- Ambicka Monika
- Ambrosino Pasquale
- Ambrosio Giuseppe
- Amin Joseph
- Amrhein Diana
- Amstutz Daniela
- An Hae Jung
- Andere Natalia
- Andersson Agneta
- Andersson Lisbeth
- Ando Hiroshi
- Ando Shinichi
- Andrzejewski Dariusz
- Angaran Paul
- Ansoult Nadege
- Antonova Petra
- Antonsen Hege
- Aoki Kenji
- Aoyama Takuma
- Appleby Nigel
- Appleby Nigel
- Aracil Villar Joaquin
- Arai Hidekazu
- Araminowicz Joanna
- Aras Funda
- Arcocha Torres Maria Fe
- Argena Antonio
- Arima Shinichi
- Armangau Pauline
- Arstall Margaret
- Asafu-Adjaye Nana
- Asano Hiroshi
- Asano Taku
- Ashraf M. Javed
- Assagay Maharajh S.
- Assouline Serge
- Astridge Penny
- Atar Dan
- Atar Dan
- Ausen Karin
- Austria Aileen
- Aves Theresa
- Avinc Gamze
- Avinc Gamze
- Avinc Gamze
- Axthelm Christoph
- Ayar Ozge
- Aydinlar Ali
- Ayres Bronte
- Azakami Shiro
- Aziz Michael
- Azuma Junya
- Baba Takao
- Babjakova Zuzana
- Babyesiza Adyeri
- Bae Sang Cheol
- Baek Ae Lee
- Baglioni Gregorio
- Bai Chunlin
- Baksh Farisha
- Balaraju Swathi
- Ball Kelly
- Bamungpong Panthipa
- Banfi Elena
- Barbarash Olga
- Barbeira Pablo Saleta
- Barkowski Timothy
- Barnes Dylan
- Barnes Dylan
- Baron Esquivias Gonzalo
- Barraquer Feu Edelmira
- Barreau Angeline
- Barreda Maria
- Barretto Antonio Carlos Pereira
- Barrow Susan
- Barry Lisa
- Bartkowiak Radoslaw
- Bartlett Melialoha
- Bartnik Jerzy
- Basiak Marcin
- Basily Wagdy
- Bassand Jean-Pierre
- Bassand Jean-Pierre
- Bassand Jean-Pierre
- Bassand Jean-Pierre
- Bastani Lisa
- Baszak Jacek
- Batalov Roman
- Batlle Javier
- Batta Claire
- Batta Claire
- Baumbach Sylvia
- Baumgartner Philipp
- Baweja Paramdeep
- Bayat Junaid
- Beattie Andre
- Becerra Munoz Victor
- Begum Haseena
- Bekieszczuk Ewa
- Belenkova Yulia
- Belenky Dmitry
- Bengtsberg Daniel
- Bennett James
- Berardi Mario
- Berg-Johansen Berg-Johansen
- Berge Eivind
- Berge Trude
- Berit Anne
- Berman Sofia Graciela
- Bernat Lukasz
- Berneau Jean-Baptiste
- Best Peggy
- Beton Osman
- Betsuyaku Tetsuo
- Beveridge Rosemary
- Bezrodna Larysa
- Bhargava Kartikeya
- Biagioli Viviana
- Bianchi Alfredo
- Biedrzycka Malgorzata
- Biedrzycka Malgorzata
- Biedrzycki Lukasz
- Biernacka Anita
- Bigcanoe Julie
- Bignell Nanci
- Bilas Roman
- Bilecen Sinan
- Billger Annelie
- Bindig Hans-Walter
- Binnekamp Maurits
- Bird Nigel
- Bireciklioglu Mustafa Fehmi
- Birhan MEHMET BİRHAN
- Bitakova Fatima
- Black Andrew
- Blenkhorn Adam
- Blinkova Marina
- Blombery Peter
- Blumberg Edwin
- Bockova Lucie
- Boda Zoltan
- Boehme Stefanie
- Boen Rigmor
- Boersma Misannia
- Boggian Giulio
- Bonet Jorge
- Bongaerts Maarten
- Bongiorni Maria Grazia
- Bonin Kerstin
- Bonkowski Grzegorz
- Bonner Michelle
- Bonnetain Anne
- Boon Jannie
- Boonyapisit Warangkana
- Boos Laura
- Booysen Maria
- Borjesson Ulf
- Borras Ana Domenech
- Boshoff Cecilia
- Bosman Femmy
- Bosschaert Mike
- Bossolasco Pierdomenico
- Botha Margo
- Bottarelli Maria Luisa
- Bouzamayor Maria Belen Lage
- Bowen-Simpkins Emma
- Bowers Suzanne
- Boys Janice
- Bradshaw Colin
- Braham Simon
- Brauer Gunter
- Bray Bryan
- Breakwell Lynn
- Bremmelgaard Arne
- Breschi Marco
- Breukel Laura
- Briceno Hinojo Ana
- Brimley Jennifer
- Broad Oulton
- Brodmann Marianne
- Bronisz Marek
- Broton Elzbieta
- Brotons Cuixart Carles
- Browne Debbie
- Bruegger Jasmine
- Brugnaux Jean Philippe
- Bruin Sandra
- Brusorio Stefania
- Bruun Michael
- Bruun Michael
- Brzustowska Malgorzata
- Buckley Elizabeth
- Buiks Paul
- Bulla Claudio
- Bultas Jan
- Bunyapipat Thanita
- Burdeina Liudmyla
- Burke Elizabeth
- Burns Stephen
- Busch Florian
- Butter Keith
- Cabrera Ramos Mercedes
- Cabrini Romina
- Caimi Teresa Maria
- Calcagnoli Francesca
- Cameron Alex
- Camm A. John
- Camm A. John
- Camm A. John
- Camm A. John
- Campagna Giuseppe
- Campo Moreno Mariela
- Campo Monica
- Cancho Corchado Gema
- Cannon Claire
- Canosa Roddy
- Canova Michaela
- Cao Shiping
- Cap Austl
- Cappelli Roberto
- Capucci Alessandro
- Carlton Lesley
- Carpenedo Monica
- Carroll Lisa
- Carroll Patrick
- Cartasegna Luis Rodolfo
- Cartwright Simon
- Casanova Gil Miguel
- Casassus Frederic
- Caspar Andreas
- Cassidy Doran
- Cassimjee Soraya
- Castillo Orive Miguel
- Castro Fernandez Daniel
- Catanchin Andrei
- Cebron Jean-Pierre
- Cervellione Kelly
- Cha James
- Cha Tae-Joon
- Chabanna Olena
- Chaiyapong Thanawan
- Chami Charmaine
- Chandwani Prakash
- Chattranukulchai Pairoj
- Chauhan Kuldeep
- Chauhan Naresh
- Cheewatanakornkul Sirichai
- Chemin Frederic
- Chen Jiyan
- Chen Kangning
- Chen Xiao
- Cheryl Laurie Ferleyko
- Cheung Stephen
- Chi Andwoo Jin
- Chiba Kei
- Chibana Hidetoshi
- Ching Chi Keong
- Chizhov Petr
- Chlumsky Jaromir
- Chmielowski Artur
- Cho Amie
- Cho Jeong-Gwan
- Cho Myeong-Chan
- Choi Dong Ju
- Choi Eun A.
- Choi Eun Hee
- Choi Hee Kyung
- Choi Hee Suk
- Chojnowski Przemyslaw
- Choudhary Fiaz
- Choudhary Ulka
- Chowan Hasan
- Christie Heather
- Christoph Marian
- Chugunnaya Svetlana
- Ciabatta Carlo
- Cichomski Rafal
- Cieslak Karol
- Cieszynska Alina
- Ciliberti Giuseppe
- Cimmino Giovanni
- Citykliniken Capio
- Clark M.
- Clarke Bonnie
- Claussen Hege
- Cleveland Tracy
- Cloak Cloak
- Coates Richard
- Coates Steven
- Coates Steven
- Colomes Anne
- Colquhoun David
- Colquhoun David
- Conn Paul
- Connolly Stuart J.
- Conway Gladys
- Cooke Philip
- Cools Frank
- Cooper Krystine
- Corbalan Ramon
- Corbalan Ramon
- Cordoba Mateo
- Corrihons Estelle
- Costa Pinto Joana
- Costello Ben
- Couleru Josette
- Coulshed David
- Coulson DrWarwick
- Coutu Benoit
- Cresp Damien
- Crisby Milita
- Cristina Leone Maria
- Croucher Alexandra
- Curyllo Bartosz
- Cymerman Krzysztof
- Czamara Marcin
- D'Agostini Erika
- D'Avino Maria
- Danielsen Mark
- Danilowicz-Szymanowicz Ludmila
- Daniuk Inna
- Danse Ingrid
- DArienzo Carmela
- Darius Harald
- Darius Harald
- Dastychova Lenka
- Date Haruhiko
- Davids Aziza
- Davies Divin
- Davies Emyr
- Davies Richard
- Davis Kent
- Dawood Dawood
- De Blasio Angelo
- De Cristofaro Raimondo
- De Graaf Judith
- de Meyer Lorinda
- Deacon Melanie
- Debordes Mirjam
- Debrunner Johann
- Debruxelles Sabrina
- Decarsin Nathalie
- Dedek Vratislav
- Dehghani Payam
- Delafontaine Patrice
- Delarche Nicolas
- Demir Mesut
- Denis Isabelle
- DePauw Jill
- Deshpande Bhakti
- Dhakrao Priyanka
- Dhillon Ripple
- Di Ancona Torrette
- Di Minno Giovanni
- Diaz Lopez Carlos Maria
- Dichristin Uta
- Diederichs Roelof
- Diercks Deborah
- Dimitri Hany
- Dixon Sue
- Dobson Simon
- Dohovits Emese
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- Dolman Marilyn
- Domanska Ewa
- Dominguez Helena
- Dominguez Helena
- Dominguez Ingrid
- Dooldeniya Chaminda
- Dorottya Kanizsai
- Dorsch Wilfried
- Douglas Kevin
- Douglass Shannen
- Drapkina Oksana
- Drasnar Tomas
- Dresser George
- Drexel Heinz
- Drown Jane
- Dshabrailov Janna
- du Preez Miranda
- Duff-Coots Margie
- Dumikyan Anait
- Dwivedi Pratik
- Dwyer Nathan
- Dybala Tomasz
- Dzeletovic Susanna
- Earath Manoj
- Ebert Hans-Holger
- Ebner Karl-Martin
- Eccleston David
- Eden Jane
- Eder Wolfgang
- Edin Anton
- Efe Jana
- Egilsson Arnor
- Egorova Liudmila
- Egyutt Mihaly
- Eikelboom John
- Eikelboom John
- Eisleben Lutherstadt
- Eissing Volker
- Ekstrand Ann-Britt
- El-Aziz Ahmed Abd
- El-Etreby Adel
- Elise Guillermet
- Elkhadem Magdi
- Ellervik Christina
- Ellis Tania
- Elmersson Micael
- Elorriaga Madariaga Ane
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- Endo Masato
- Engdahl Johan
- Engelbrecht Johannes
- Engelthaler Gabriella
- Epelde Gonzalo Francisco
- Erdle Werner
- Erga Knut
- Ericsson Marianne
- Ersanli Murat
- Eskandari Mehdi
- Eslick Renee
- Espallargas Anna
- Estifanos Salah
- Eto Takuma
- Evans Lorlie
- Evans Paul
- Evans Phil
- Ewald Gregory
- Ewert Alayna
- Fairhead Sue
- Fanelli Raffaele
- Faron Andwojciech
- Farquhar Donald
- Fattore Luciano
- Fearon Ann
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- Felekoglu Mehmet Ali
- Felpel Susan
- Femiano Claudio
- Feng Shuai
- Feola Mauro
- Ferdinand Keith
- Ferenczi Judit
- Ferkl Richard
- Fernandez Escobar Esther
- Ferreira-Jardim Antonio
- Ferreira-Jardim Antonio
- Ferrer Ana
- Ferrini Piera Maria
- Fetahovic Taufik
- Fielder Debbie
- Figura-Chmielewska Monika
- Figura-Chmielewska Monika
- Fikry Sameh
- Fikry Sameh
- Finlaison Judy Anne
- Fitzmaurice David
- Fitzmaurice David A.
- Fitzmaurice David A.
- Fitzpatrick Michael
- Fleck Anja
- Fleury Julie
- Flint Kerstin
- Floegel Hildegard
- Floren Karin
- Flynn Ann
- Foechterle Johannes
- Foechterle Johannes
- Fontanillas Maria Teixido
- Foo David
- Fooks Tim
- Foppa Luciano
- Forcignano Fulvio
- Forgo Veronika
- Forshaw Karen
- Fournier Denise
- Fox Beverley
- Fox Keith A. A.
- Fox Robin
- Frankiewicz Anna
- Franklin Simon
- French John
- Frick Marcel
- Fritella Roberta
- Frittella Roberta
- Fudo Tetsuro
- Fujii Masako
- Fujii Yuichi
- Fujiki Rei
- Fujimoto Shunichi
- Fujisawa Akinori
- Fujisawa Yasuaki
- Fujito Tsuneo
- Fujiura Yoshihisa
- Fujiura Yoshitake
- Fukuda Tsuyoshi
- Funda Balci
- Furukawa Nobufusa
- Furukawa Yoshiyuki
- Furumoto Wataru
- Fushtey Ivan
- Gadzinski Andwaldemar
- Galinier Michel
- Galloway Sophia
- Garcia Bermudez Miriam
- Garcia Millan Venesa
- Garcia Jorge
- Garda Riaz
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- Gasior Ewa
- Gasior Ewa
- Gaudreault Julie
- Gaudreault Julie
- Gavira Saenz Marga
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- Gergely Szilvia
- Germini Fabrizio
- Ghezai Beraki
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- Gibbs Harry
- Gibbs Janene
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- Gilliand A.
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- Girke Friederike
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- Gladbach Bergisch
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- Glanowska Grazyna
- Glatzel Dirk
- Glencross Janet
- Goda Toshihiro
- Goldhaber Samuel Z.
- Goldhaber Samuel Z.
- Goldhaber Samuel Z.
- Goldhaber Samuel Z.
- Goldhaber Samuel Z.
- Golino Paolo
- Gombos Petra
- Gomez Castillo Carmen
- Gomez Pajuelo Casimiro
- Gomez Lola
- Gonzalez Juanatey Jose Ramon
- Gonzalez Paz
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- Gruchala Marcin
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- Guazzaloca Giuliana
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- Guenther Franziska
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- Guinand Alexandre
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- Han Sunhui
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- Handel Hans
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- Haq Ikram
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- Hargreaves Nick
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- Hart Nigel
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- Hasegawa Koichi
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- Haverkamp Wilhelm
- Hawkins Benji
- Hayashi Yoshihito
- Hayes Kate
- He Ruhua
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- Henriette Isberg
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- Heradien Marshall
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- Herrman Jean-Paul
- Hesketh Leverne
- Heuer Adrienne
- Hevia Rodriguez Eduardo
- Hey Heinz
- Heyvang Nathalie
- Hibino Michitaka
- Hicks Teresa
- Hiczkiewicz Jaroslaw
- Higa Satoshi
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- Higgs Megan
- Higuchi Koji
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- Hiramitsu Shinya
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- Hirst Rob
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- Hoddy Sally-Anne
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- Honda Masaaki
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- Horstmeier Uwe
- Hoshiai Mitsumoto
- Hosokawa Hiroaki
- Hosokawa Hiroshi
- Hot-Bjelak Aida
- Howard Joy
- Hruczkowski Tomasz
- Hu Dayi
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- Huang Xingfu
- Huber Kurt
- Hubert Katja
- Hubrich Christl
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- Hwang Eunjung
- Hwang Gyo-Seung
- I Llibre Joan Bayo
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- Ido Takahisa
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- Iglesias Alonso Luis Fernando
- Iiji Osamu
- Ikeda Hideo
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- Iniguez Romo Andres
- Irvine Gordon
- Isaacs Anna
- Isabel Cotilla Maria
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- Ishiguro Motoyuki
- Ishioka Norio
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- Ison Rodney
- Ito Kenichiro
- Ito Nobuhisa
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- Jackson Ana Maria
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- Jain Dinesh
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- Jaremczuk-Kaczmarczyk Adriana
- Jarzebowski Artur
- Jasinski Sarah
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- Jerabek Ondrej
- Jetten Andwesley
- Jimenez Fernandez Maria Jose
- Jimenez Navarro Manuel
- Johnson Katherine
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- Jung Byung Chun
- Jurowiecki Jaroslaw
- Kaat Josine Te
- Kadappu Krishna
- Kadouch James
- Kaewsuwanna Pinij
- Kahl Friedhelm
- Kahlon Ranjit
- Kakkar Ajay K.
- Kakkar Ajay K.
- Kakuda Hirokazu
- Kamath R.
- Kameko Masahiro
- Kamenska Ellina
- Kamin Susanne
- Kammermayer Michael
- Kamogawa Yasuyuki
- Kanai Hideaki
- Kanakaridisz Nikosz
- Kanamori Seishu
- Kanda Hirofumi
- Kaneko Masanori
- Kang Jisun
- Kangert Rose-Mari
- Kangert Rose-Mari
- Kania Grzegorz
- Kaplan Pavlo
- Kaplan Sally
- Karl Susan
- Karolyi Laszlo
- Karpenko Oleksandr
- Karsten Marinda
- Kasai Takeaki
- Kassam Imran
- Katekangplu Peerapat
- Kato Yoji
- Kato Yoji
- Katsube Yoshiki
- Katsuya Tomohiro
- Kaur Sukhjeet
- Kawada Yuka
- Kawakami Shuichi
- Kawano Yoshiyuki
- Kayani Gloria
- Kayani Gloria
- Keeling Mickie
- Kelfkens Ynez
- Kellner Bernd-Thomas
- Kelly Sheila
- Keltai Matyas
- Kemmel Agnes
- Kerr Jowanna
- Keten Murdem
- Kettles David
- Khairy Tarek
- Khattaroek Rudeewan
- Khmelyova Alina
- Khokhlov Alexander
- Khunkong Ketsanee
- Khunrong Porames
- Khyzhnyak Olena
- Kilian Jens
- Kiliszek Marek
- Kim Dae-Kyeong
- Kim Haeim
- Kim Jaeyoung
- Kim JiSeon
- Kim Juhee
- Kim Kee-Sik
- Kim Ki Tae
- Kim Mi Sun
- Kim Nam-Ho
- Kim Richard
- Kim Sang Hee
- Kim Sang Hyun
- Kim Sun-Joo
- Kim Woo-Shik
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- Tsuruta Makoto
- Tsuzaki Ken
- Turpie Alexander G. G.
- Turpie Alexander G. G.
- Tybura Sebastian
- Tybura Sebastian
- Tykhonova Susanna
- Ubeda Pastor Maria
- Ubukata Satoshi
- Uchiyama Hirohide
- Ueckermann Andre
- Ueckermann Veronica
- Ueda Osamu
- Ueda Takashi
- Ueda Takashi
- Ueda Tomohiro
- Ueyama Yuya
- Ulbrich Andreas
- Ullah Inaam
- Uppelschoten Boudewijn
- Upton Deirdre
- Uriate Jorge Salerno
- Ushakov Alexey
- Ushakov Oleksiy
- Valtova Martina
- van Eickels Martin
- van Gaal William
- van Putten Jan Jaap
- van Zyl Francois
- van Zyl Lelanie
- van Zyl Louis
- Vandamme Xavier
- Vandrus Boglarka
- Vangel Sandor
- Vardcentral Sunne
- Vardon Elizabeth
- Vardon Elizabeth
- Varol Sinan
- Vazquez Caamano Maria
- Vazquez Gloria Millan
- Veale Richard
- Vercoe Stephen
- Verheugt Freek W. A.
- Verheugt Freek W. A.
- Vertes Andras
- Vicic Judy
- Vicic Judy
- Vida Gutierrez Manuel
- Vila Alicia Martin
- Villani Rosanna
- Vinolas Xavier
- Vishnevsky Alexander
- Vizel Saul
- Voelkel-Babyesiza Regina
- Voigts Birgit
- Volodicheva Olga
- Volpe Massimo
- Vonbank Alexander
- Vorasettakarnkij Yongkasem
- Vormann Reinhold
- Vorster Mary
- Vorster Mary
- Vue Belle
- Vyhlidalova Veronika
- Wada Masamichi
- Wagner Helga
- Wakeling John
- Wakeman Anne
- Waldman Alla
- Walker Martin
- Walko Bogdan
- Wang Daowen
- Wang Y.
- Wang Yong
- Warke A.
- Wastling Rebecca
- Webster Chelsea
- Wegmayr Claudia
- Wegrzynowska Marta
- Wegrzynowska Marta
- Weichelt Sylvia
- Weiser Ute
- Weitbrecht Luis
- Welker James
- Wesolowska Kamila
- Wielkopolska Sroda
- Wierzbicka Aleksandra
- Wildenauer Cosmas
- Wilford Emily
- Williams Celestine
- Williams Philip
- Wilson Pete
- Wilson Vance
- Winkler Helga
- Winnik Stephan
- Wirdby Alexander
- Wisaratapong Treechada
- Wiswedel Henning
- Wohrer Claudia
- Wolf Thomas
- Wong Bennett
- Wong Mike
- Wongtheptien Andwattana
- Wood Annette
- Wood Kristine
- Woody Jill
- Worthy Vanetta
- Wozakowska-Kaplon Beata
- Wozniak-Skowerska Iwona
- Wright Debbie
- Wurziger Juergen
- Xue Li
- Yagensky Andriy
- Yakupov Eduard
- Yamada Takehiro
- Yamaguchi Hiroshi
- Yamamoto Kenichi
- Yamamoto Kentaro
- Yamamoto Kiichiro
- Yamamoto Kunihiko
- Yamamoto Taku
- Yamasawa Masanori
- Yamaura Makoto
- Yamazoe Masahiro
- Yang Jingshan
- Yang Lingli
- Yang Zhiming
- Yawila Suree
- Yildirim Rifat
- Yilmaz Faruk
- Yilmaz Ozcan
- Yokota Naoto
- Yokoyama Yasuhiro
- Yoon Eunji
- Yoon Jung Han
- Yoshida Keiki
- Yoshida Tetsuro
- Yoshida Tomohiro
- Yoshida Tomoki
- Yoshimura Akira
- Yoshizawa Naoto
- Yu HyunJu
- Yu Ting
- Yusuf Huma
- Yuyang Tan
- Zaatout Eman
- Zaitsu Ryuji
- Zak Jan
- Zakutynska-Kowalczyk Karolina
- Zaluska Roman
- Zaman Kashif
- Zateyshchikov Dmitry
- Zauzig Heinz-Dieter
- Zdrowotnej Zespol Opieki
- Zecca Cinzia
- Zemlianskaia Oksana
- Zhai Hong
- Zhan Qiong
- Zhang Guoshan
- Zhang Huaiqin
- Zhang Ran
- Zhang Yi
- Zhao Yusheng
- Zhuravleva Evgeniya
- Zidek Milan
- Zidkova Eva
- Zika Jiri
- Zillo Mariana
- Zimmett Leon
- Zimny Hans-Hermann
- Zincke Stephanie
- Zinka Elzbieta
- Zinka Elzbieta
- Zotova Irina
- Zubeeva Galina
- Zuber Mathieu
- Zutz Stefan
- Zwenkau Schwarz
- Zyczynska Malgorzata
- Publication venue
- 'American Medical Association (AMA)'
- Publication date
- 01/06/2019
- Field of study
IMPORTANCE Congestive heart failure (CHF) is commonly associated with nonvalvular atrial fibrillation (AF), and their combination may affect treatment strategies and outcomes