1,557 research outputs found

    Identification of autism spectrum disorder using deep learning and the ABIDE dataset

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    The research was supported by CAPES, Brazilian Ministry of Education (Projeto ACERTA CAPES/OBEDUC 0898/2013; number 23038.002530/2013-93Peer reviewe

    Extrathymic CD4+CD8+ lymphocytes in Chagas disease: Possible relationship with an immunoendocrine imbalance

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    Double positive CD4+CD8+ (DP) T cells normally represent a thymic subpopulation that is developed in the thymus as precursors of CD4+ or CD8+ single-positive T cells. Recent evidence showed that DP cells could be also tracked in secondary lymph organs showing an activated phenotype. The detection of DP activated population in the periphery that bears T cell receptors unselected during the thymic negative selection of either murine models of Trypanosoma cruzi infection and similar findings in human with Chagas disease raise new questions about the relevance of this population in the pathogenesis of this major parasitic disease and their possible links with immunoendocrine alterations.Fil: Perez, Ana Rosa. Universidad Nacional de Rosario. Facultad de Ciencias Médicas. Instituto de Inmunología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Rosario; ArgentinaFil: Morrot, Alexandre. Universidade Federal do Rio de Janeiro; BrasilFil: Berbert, Luiz R.. Fundación Oswaldo Cruz; BrasilFil: Terra Granado, Eugenia. Fundación Oswaldo Cruz; BrasilFil: Savino, Wilson. Fundación Oswaldo Cruz; Brasi

    Diclidophora luscae (Monogenea: Diclidophoridae) in pouting, Trisopterus luscus (Linnaeus, 1758) from the northeast Atlantic; epidemiology, morphology, molecular and phylogenetic analysis

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    Diclidophora (Monogenea) species are gill parasites with a stenoxenic specifcity occurring only in Gadiformes. Epidemiologi‑cal, morphological, molecular and phylogenetic studies were performed on 594 Diclidophora specimens collected from 213 Trisopterus luscus captured in the northeast Atlantic of the Portuguese coast during 2012, 2013 and 2020. Prevalence, parasite abundance and infection intensity were determined. Positive correlation between fsh weight and length and infection intensity was observed. The efects of preservation on the parasite morphological features were studied, highlighting that specimen’s identifcation should be reinforced by molecular studies. A sequence of D. luscae capelanii from T. capelanus captured in the Mediterranean Sea included in the 28S rDNA molecular analysis was nested within a robust D. luscae clade. Data analysis suggested that this species is in fact D. luscae, which is compatible with T. luscus and T. capelanus. The identity of fsh hosts was confrmed by barcoding. For the frst time, data on the infection parameters is shown, highlighting the importance of including this parasite in the monitoring plans for a holistic approach with possible efects for the management of pouting resources aiming of attaining sustainable development and biodiversity conservation measures, according to the 14th objective of the 2030 agendainfo:eu-repo/semantics/publishedVersio

    Truncated Star Formation in Compact Groups of Galaxies: A Stellar Population Study

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    We present the results of a study comparing the stellar populations in the elliptical galaxies of Hickson Compact Groups (HCGs) with those in low density environments. Three different population synthesis models and stellar population analyses are used to make the results more robust. The low-sigma galaxies in HCGs show an enhanced [Mg/Fe] ratio and a depleted metallicity [Z/H] with respect to their counterparts in the field. This behavior is interpreted as evidence for the action of a mechanism which truncated the star formation (SF). Hydrodynamical simulations of galaxy mergers (Di Matteo et al. 2005) support this interpretation by predicting the quenching of star formation soon after the merger event. Combining this scenario and the evidence presented here, the HCGs, generally considered to be ideal environments for galaxy-galaxy interactions, become ideal places for SF truncation.Comment: 18 pages, 9 figures. Accepted for publication in Astronomical Journa

    PRODOWN: programa de avaliação da aptidão física de crianças e jovens com Síndrome de Down - Normas de avaliação da aptidão física

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    PRODOWN fue desarrollado para la población de niños y jóvenes con Síndrome de Down (SD) entre 10 y 20 años. El programa está disponible en Internet con libre acceso. Objetivo: Los objetivos son describir, acompañar y analizar el comportamiento del crecimiento corporal, de la aptitud física, del estado nutricional y de los hábitos de vida de jóvenes con SD.PRODOWN was developed for the population of children and young people with Down’s Syndrome (DS) between 10 and 20 years. The program is available on the Internet with open access. Objective: The objectives are to describe, conduct and analyze the behavior of body growth, physical fitness, nutritional status and life habits of young people with DS.O PRODOWN foi desenvolvido para a população de crianças e jovens com Síndrome de Down (SD) entre 10 e 20 anos. O programa está disponível na internet com livre acesso. Objetivo: Os objetivos são de descrever, acompanhar e analisar o comportamento do crescimento corporal, da aptidão física, do estado nutricional e dos hábitos de vida de jovens com SD.peerReviewe

    Revealing the Chemical Structure of the Magellanic Clouds with APOGEE. II. Abundance Gradients of the Large Magellanic Cloud

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    We present the abundance gradients of the Large Magellanic Cloud (LMC) for 25 elemental abundance ratios and their respective temporal evolution as well as age-[X/Fe] trends using 6130 LMC field red giant branch (RGB) stars observed by SDSS-IV / APOGEE-2S. APOGEE is a high resolution (RR \sim22,500) HH-band spectroscopic survey that gathered data on the LMC with broad radial and azimuthal coverage out to \sim10\degr. The calculated overall metallicity gradient of the LMC with no age binning is -0.0380 ±\pm 0.0022 dex/kpc. We also find that many of the abundance gradients show a U-shaped trend as functions of age. This trend is marked by a flattening of the gradient but then a general steepening at more recent times. The extreme point at which all these gradients (with the U-shaped trend) begin to steepen is \gtrsim2 Gyr ago. In addition, some of the age-[X/Fe] trends show an increase starting a few Gyr before the extreme point in the gradient evolutions. A subset of the age-[X/Fe] trends also show maxima concurrent with the gradients' extreme points, further pinpointing a major event in the history of the LMC \sim2 Gyr ago. This time frame is consistent with a previously proposed interaction between the Magellanic Clouds suggesting that this is most likely the cause of the distinct trend in the gradients and age-[X/Fe] trends.Comment: 25 pages, 19 figures, and 10 table

    Systematic variation of the stellar Initial Mass Function with velocity dispersion in early-type galaxies

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    An essential component of galaxy formation theory is the stellar initial mass function (IMF), that describes the parent distribution of stellar mass in star forming regions. We present observational evidence in a sample of early-type galaxies (ETGs) of a tight correlation between central velocity dispersion and the strength of several absorption features sensitive to the presence of low-mass stars. Our sample comprises ~40,000 ETGs from the SPIDER survey (z<0.1). The data, extracted from the Sloan Digital Sky Survey, are combined, rejecting both noisy data, and spectra with contamination from telluric lines, resulting in a set of 18 stacked spectra at high signal-to-noise ratio (S/N> 400 per A). A combined analysis of IMF-sensitive line strengths and spectral fitting is performed with the latest state-of the art population synthesis models (an extended version of the MILES models). A significant trend is found between IMF slope and velocity dispersion, towards an excess of low-mass stars in the most massive galaxies. Although we emphasize that accurate values of the IMF slope will require a detailed analysis of chemical composition (such as [a/Fe] or even individual element abundance ratios), the observed trends suggest that low-mass ETGs are better fit by a Kroupa-like IMF, whereas massive galaxies require bottom-heavy IMFs, exceeding the Salpeter slope at velocity dispersions above 200km/s.Comment: 5 pages, 4 figures, accepted for publication in MNRAS Letter
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