36 research outputs found
Prospective study of urinary tract infection surveillance after kidney transplantation
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/01/2010
- Field of study
<p>Abstract</p> <p>Background</p> <p>Urinary tract infection (UTI) remains one of the main complications after kidney transplantation and it has serious consequences.</p> <p>Methods</p> <p>Fifty-two patients with kidney transplantation were evaluated for UTI at 3-145 days (mean 40.0 days) after surgery.. Forty-two received a graft from a live donor and 10 from a deceased donor. There were 22 female and 30 male patients, aged 11-47 years. Microscopic examinations, leukocyte esterase stick, and urinary culture were performed every third day and weekly after hospitalization. A positive culture was consider when patients presented bacterial counts up to 10<sup>5</sup> counts.</p> <p>Results</p> <p>UTI developed in 19/52 (37%) patients at 3-75 days (mean 19.5 days after transplantation. Recurrent infection was observed in 7/52 (13.4%) patients at days 17-65. UTI was more frequent in patients who received deceased grafts compared with live grafts (7/10, 70% <it>vs</it>. 12/42, 28%; p < 0.007). Female patients were more susceptible than male (11/22, 50% <it>vs</it>. 8/22, 36.35%; p < 0.042). Five-year survival rate was 94.5% (49/52 patients). Kidney Graft exit update is 47/52 (90.2%), and there were no significant differences between graft rejection and UTI (p = 0.2518). Isolated bacteria were <it>Escherichia coli </it>(31.5%), <it>Candida albicans </it>(21.0%) and <it>Enterococcus </it>spp. (10.5%), followed by <it>Pseudomonas aeruginosa, Klebsiella pneumoniae, Morganella </it><it>morganii, Enterobacter cloacae </it>and <it>Micrococcus </it>spp. Secondary infections were produced by (7/19, 36.8%). <it>Enterococcus </it>spp. (57%), <it>E. coli </it>(28%) and <it>Micrococcus </it>spp. (14.2%). Antibiotic resistance was 22% for ciprofloxacin and 33% for ampicillin. Therapeutic alternatives were aztreonam, trimethoprim-sulfamethoxazole, netilmicin and fosfomycin.</p> <p>Conclusions</p> <p>Surveillance of UTI for the first 3 months is a good option for improving quality of life of kidney transplantation patients and the exit of graft function especially for female patients and those receiving deceased grafts. Antibiograms provided a good therapeutic alternative to patients who presented with UTIs after receiving a kidney allograft.</p
Enfrentando los riesgos socionaturales
- Author
- ARAGON GONZALEZ RAFAEL
- ARAGON GONZALEZ RAFAEL
- ARRIAGA RIVERA ARMANDO
- ARRIAGA RIVERA ARMANDO
- BA KHALIDOU MAMADOU
- BA KHALIDOU MAMADOU
- BARO SUAREZ JOSE EMILIO
- BARO SUAREZ JOSE EMILIO
- CABADAS BAEZ HECTOR VICTOR
- CABADAS BAEZ HECTOR VICTOR
- CADENA VARGAS EDEL
- CADENA VARGAS EDEL
- CAMPOS VARGAS MARIA MILAGROS
- CAMPOS VARGAS MARIA MILAGROS
- CARBAJAL MONROY JULIO CESAR
- CARBAJAL MONROY JULIO CESAR
- DAVILA HERNANDEZ NORMA ANGELICA
- DAVILA HERNANDEZ NORMA ANGELICA
- DIAZ DELGADO CARLOS
- DIAZ DELGADO CARLOS
- DIAZ SANCHEZ SRAHYRLANDY ROCIO
- DIAZ SANCHEZ SRAHYRLANDY ROCIO
- Espinosa Rodríguez Luis Miguel
- Espinosa Rodríguez Luis Miguel
- EXPOSITO CASTILLO JOSE LUIS
- EXPOSITO CASTILLO JOSE LUIS
- FRAUSTO MARTINEZ OSCAR
- FRAUSTO MARTINEZ OSCAR
- GARATACHIA RAMIREZ JUAN CARLOS
- GARATACHIA RAMIREZ JUAN CARLOS
- GAYTAN INIESTRA JUAN
- GAYTAN INIESTRA JUAN
- GOMEZ ALBORES MIGUEL ANGEL
- GOMEZ ALBORES MIGUEL ANGEL
- Gutiérrez Cedillo Jesús Gastón
- Gutiérrez Cedillo Jesús Gastón
- HERNANDEZ SANTANA JOSE RAMON
- HERNANDEZ SANTANA JOSE RAMON
- HERNANDEZ VALDES ROSA ESTELA
- HERNANDEZ VALDES ROSA ESTELA
- HUERTA LOPEZ CARLOS ISIDRO
- HUERTA LOPEZ CARLOS ISIDRO
- JAIMES VIERA MARIA DEL CARMEN
- JAIMES VIERA MARIA DEL CARMEN
- LOPEZ BLANCO JORGE
- LOPEZ BLANCO JORGE
- MASTACHI LOZA CARLOS ALBERTO
- MASTACHI LOZA CARLOS ALBERTO
- Monroy Gaytán José Francisco
- Monroy Gaytán José Francisco
- Méndez Linares Ana Patricia
- Méndez Linares Ana Patricia
- NIETO TORRES AMIEL
- NIETO TORRES AMIEL
- ORDAZ HERNANDEZ ALEXIS
- ORDAZ HERNANDEZ ALEXIS
- REYES LOPEZ HECTOR ALONSO
- REYES LOPEZ HECTOR ALONSO
- THOMAS BOHORQUEZ JAVIER ENRIQUE
- THOMAS BOHORQUEZ JAVIER ENRIQUE
- ZEPEDA MONDRAGON FRANCISCO
- ZEPEDA MONDRAGON FRANCISCO
- Publication venue
- Clave editorial
- Publication date
- 01/01/2018
- Field of study
El objetivo del libro es comprender la magnitud de los Riesgos Socionaturales en México y Latinoamérica, para comprender el peligro que existe por algún tipo de desastre, ya sea inundaciones, sismos, remoción en masa, entre otros, además conocer qué medidas preventivas, correctivas y de contingencias existen para estar atentos ante alguna señal que la naturaleza esté enviando y así evitar alguna catástrofe. El libro se enfoca en los aspectos básicos de análisis de los peligros, escenarios de riesgo, vulnerabilidad y resiliencia, importantes para la gestión prospectiva o preventiva
Why Are Outcomes Different for Registry Patients Enrolled Prospectively and Retrospectively? Insights from the Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF).
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- A'Court C.
- Aaroe H.
- Abd El-Aziz A.
- Abdalla Saad J.
- Abdel-Qader M.
- Abdelrahman H.
- Abdul A.
- Abe M. (Masahiko)
- Abe M. (Masatake)
- Abe M. (Mitsunori)
- Abe S.
- Abe Y.
- Abhayaratna W.
- Abou Seif S. K.
- Abraham S.
- Abu-Mahfouz M.
- Abushal S.
- Accetta Gabriele
- Accogli M.
- Adachi S.
- Adachi S. (Sen)
- Adachi S. (Susumu)
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- Al Mahmeed W.
- Al Mahmeed Wael
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- Wesendorf S.
- Wesolowska K.
- West R.
- Westerlund Montera M.
- Westerman L.
- Wetherwell S.
- Weyn T.
- Wi H. K.
- Wieczorek W.
- Wierzbicka A.
- Wilczewski P.
- Wildenauer S.
- Wildenauer W.
- Wilford E.
- Wilgat-Szecowka M.
- Wilkinson J.
- Willcock W.
- Williams A.
- Williams M.
- Wilson A.
- Wilson P.
- Wilson V
- Winkler M.
- Winnik S.
- Wirdby A.
- Wisaratapong T.
- Wiswedel H.
- Woehrer C.
- Wojewoda P.
- Wojnowski L.
- Wolf T.
- Wollaert B.
- Wong K.
- Wong M.
- Wong S.
- Wong S. W.
- Wong T.
- Wongcharoen W.
- Wongtheptien W.
- Woo J. J.
- Worthy V
- Wozakowska-Kaplon B.
- Wozniak-Skowerska I
- Wright D.
- Wrobel M.
- Wu R. N.
- Wu T. G.
- Wurziger J.
- Wutthimanop A.
- Xhaet O.
- Xie Q.
- Xiong L. G.
- Xu R. Y.
- Xue L.
- Yagensky A.
- Yakupov E.
- Yamada T.
- Yamagishi T.
- Yamaguchi H.
- Yamamoto K.
- Yamamoto K. (Kenichi)
- Yamamoto K. (Kentaro)
- Yamamoto K. (Kunihiko)
- Yamamoto T.
- Yamasawa M.
- Yamaura M.
- Yamazoe M.
- Yan X. W.
- Yang J. S.
- Yang L. L.
- Yang P.
- Yang Q.
- Yang Y. J.
- Yang Z. M.
- Yap S. Y.
- Yasui K.
- Yawila S.
- Ye S.
- Ye Y.
- Yeo C.
- Yeter E.
- Yildirim E.
- Yildirim R.
- Yilmaz F.
- Yilmaz M. B.
- Yilmaz O.
- Yim K. H.
- Yin Y. H.
- Yokota N.
- Yokoyama Y.
- Yong R.
- Yoo K. M.
- Yoon E. J.
- Yoon J. H.
- Yorgun H.
- Yoshida H.
- Yoshida K.
- Yoshida T. (Tetsuro)
- Yoshida T. (Tomoki)
- Yoshimura A.
- Yoshizawa N.
- Yousef G.
- Yu H. Y.
- Yu J. H.
- Yu T.
- Yuksekdag V
- Yun S. Y.
- Yunis M. E.
- Zaatout E.
- Zaidi S. M. A.
- Zaitsu R.
- Zak J.
- Zakutynska-Kowalczyk K.
- Zaluska R.
- Zaman K.
- Zanolin D.
- Zapata G.
- Zateyshchikov D.
- Zateyshchikova A.
- Zauzig H-D
- Zauzig H.
- Zecca C.
- Zemlianskaia O.
- Zhai H.
- Zhan Q.
- Zhang G. S.
- Zhang H. Q.
- Zhang Q.
- Zhang R.
- Zhang Y.
- Zhao R. P.
- Zhao Y. S.
- Zheng W. Y.
- Zhirov I
- Zhou B.
- Zhou Z. H.
- Zhu X. Y.
- Zhuravleva E.
- Zhurba S.
- Zidek M.
- Zidkova E.
- Ziefle S.
- Zika J.
- Zillo M.
- Zimmett L.
- Zimny H-H
- Zincke S.
- Zinka E.
- Zotova I
- Zrazhevskiy K.
- Zubeeva G.
- Zuber M.
- Zurbrigk F. J.
- Zutz S.
- Zyczynska-Szmon M.
- Publication venue
- 'Oxford University Press (OUP)'
- Publication date
- 01/01/2018
- Field of study
Background: Retrospective and prospective observational studies are designed to reflect real-world evidence on clinical practice, but can yield conflicting results. The GARFIELD-AF Registry includes both methods of enrolment and allows analysis of differences in patient characteristics and outcomes that may result. Methods and Results: Patients with atrial fibrillation (AF) and ≥1 risk factor for stroke at diagnosis of AF were recruited either retrospectively (n = 5069) or prospectively (n = 5501) from 19 countries and then followed prospectively. The retrospectively enrolled cohort comprised patients with established AF (for a least 6, and up to 24 months before enrolment), who were identified retrospectively (and baseline and partial follow-up data were collected from the emedical records) and then followed prospectively between 0-18 months (such that the total time of follow-up was 24 months; data collection Dec-2009 and Oct-2010). In the prospectively enrolled cohort, patients with newly diagnosed AF (≤6 weeks after diagnosis) were recruited between Mar-2010 and Oct-2011 and were followed for 24 months after enrolment. Differences between the cohorts were observed in clinical characteristics, including type of AF, stroke prevention strategies, and event rates. More patients in the retrospectively identified cohort received vitamin K antagonists (62.1% vs. 53.2%) and fewer received non-vitamin K oral anticoagulants (1.8% vs . 4.2%). All-cause mortality rates per 100 person-years during the prospective follow-up (starting the first study visit up to 1 year) were significantly lower in the retrospective than prospectively identified cohort (3.04 [95% CI 2.51 to 3.67] vs . 4.05 [95% CI 3.53 to 4.63]; p = 0.016). Conclusions: Interpretations of data from registries that aim to evaluate the characteristics and outcomes of patients with AF must take account of differences in registry design and the impact of recall bias and survivorship bias that is incurred with retrospective enrolment. Clinical Trial Registration: - URL: http://www.clinicaltrials.gov . Unique identifier for GARFIELD-AF (NCT01090362)
Educación ambiental y sociedad. Saberes locales para el desarrollo y la sustentabilidad
- Author
- Agudelo Cadavid Ruth Marina
- Agudelo Cadavid Ruth Marina
- Araya Fredy
- Araya Fredy
- Ascuy Morales Arely Beatriz
- Ascuy Morales Arely Beatriz
- Bordón Cruz Abel
- Bordón Cruz Abel
- Bordón Cruz Abel
- Bordón Cruz Abel
- Bordón Durán Lisabel
- Bordón Durán Lisabel
- Borroto Pérez María
- Borroto Pérez María
- BUSTILLOS GOMEZ AREOPAGITA YESYKA
- BUSTILLOS GOMEZ AREOPAGITA YESYKA
- Campos Díaz José Luis Venancio
- Campos Díaz José Luis Venancio
- Carballo Cruz Edianny
- Carballo Cruz Edianny
- Carballo Ramos Elme
- Carballo Ramos Elme
- Castillo Castillo José Luis Miguel
- Castillo Castillo José Luis Miguel
- COUDER CASTAÑEDA CARLOS
- COUDER CASTAÑEDA CARLOS
- CRUZ SOTELO GABRIELA ARELI
- CRUZ SOTELO GABRIELA ARELI
- Delgado Knight Marla Iris
- Delgado Knight Marla Iris
- Durán García Lissette
- Durán García Lissette
- Durán García Lissette
- Durán García Lissette
- ESCOBAR MORENO DARIO ALEJANDRO
- ESCOBAR MORENO DARIO ALEJANDRO
- Espinosa Ayala Enrique
- Espinosa Ayala Enrique
- Gabriel Hernández Loarry-Isaura
- Gabriel Hernández Loarry-Isaura
- Gabriel Hernández Loarry-Isaura
- Gabriel Hernández Loarry-Isaura
- Gil Valencia Julián David
- Gil Valencia Julián David
- GOMEZ LOZOYA ENRIQUE ARMANDO
- GOMEZ LOZOYA ENRIQUE ARMANDO
- Goméz Vidal Anabell
- Goméz Vidal Anabell
- González Agudelo Elvia María
- González Agudelo Elvia María
- HERNANDEZ GARCIA PEDRO ABEL
- HERNANDEZ GARCIA PEDRO ABEL, 41875
- HERNANDEZ RODRIGUEZ CUITLAHUAC VICTOR
- HERNANDEZ RODRIGUEZ CUITLAHUAC VICTOR
- JUAREZ TOLEDO RAUL
- JUAREZ TOLEDO RAUL
- Juárez Toledo Werther
- Juárez Toledo Werther
- Knight Soto Idarmis
- Knight Soto Idarmis
- LASTIRI SALAZAR ANGELICA
- LASTIRI SALAZAR ANGELICA
- LLAMAS GONZALEZ ALVARO
- LLAMAS GONZALEZ ALVARO
- LUNA MATA MARCO ANTONIO
- LUNA MATA MARCO ANTONIO
- MAGALLANES MENDEZ MARIA DEL CARMEN
- MAGALLANES MENDEZ MARIA DEL CARMEN
- Mar Olivares Héctor Manuel
- Mar Olivares Héctor Manuel
- MARTINEZ SALDAÑA TOMAS
- MARTINEZ SALDAÑA TOMAS
- MENDOZA TELLO ENRIQUE
- MENDOZA TELLO ENRIQUE
- Montoya Rendón María Luisa
- Montoya Rendón María Luisa
- Morales Gutiérrez Fredy
- Morales Gutiérrez Fredy
- NORIEGA VALENCIA GABRIELA
- NORIEGA VALENCIA GABRIELA
- Ochoa González Marisol
- Ochoa González Marisol
- OJEDA CARRASCO JUAN JOSE
- OJEDA CARRASCO JUAN JOSE
- Ordóñez Cepeda Fausto Eduardo
- Ordóñez Cepeda Fausto Eduardo
- PERALES SALVADOR ARTURO
- PERALES SALVADOR ARTURO
- PEREZ HERNANDEZ LUZ MARIA
- PEREZ HERNANDEZ LUZ MARIA
- Pérez Garcés Ranulfo
- Pérez Garcés Ranulfo
- Quesada monge Ruperto
- Quesada monge Ruperto
- QUINTERO LOPEZ IRMA
- QUINTERO LOPEZ IRMA
- QUINTERO SOTO MARIA LUISA
- QUINTERO SOTO MARIA LUISA
- Quispe Limaylla Aníbal
- Quispe Limaylla Aníbal
- Ramírez Roque Delsi
- Ramírez Roque Delsi
- RIVERA CRUZ MARIA LETICIA
- RIVERA CRUZ MARIA LETICIA
- RIVERA ESPINOSA RAMON
- RIVERA ESPINOSA RAMON
- Rodríguez Pérez Lucas
- Rodríguez Pérez Lucas
- ROJAS GONZALEZ ZULEIMA
- ROJAS GONZALEZ ZULEIMA
- RUEDA HERNANDEZ HECTOR
- RUEDA HERNANDEZ HECTOR
- RUIZ GONZALEZ ROSEY OBET
- RUIZ GONZALEZ ROSEY OBET
- Sales Colín Jesús
- Sales Colín Jesús
- SANCHEZ CARRASCO MARIA JOAQUINA
- SANCHEZ CARRASCO MARIA JOAQUINA
- Santos Rodas Yendi Yomara
- Santos Rodas Yendi Yomara
- Solano Ramos Romulo Agustin
- Solano Ramos Romulo Agustin
- Suárez Varela Iztaccíhuatl
- Suárez Varela Iztaccíhuatl
- Sánchez Medince Luis Arturo
- Sánchez Medince Luis Arturo
- TELLO GARCIA ENRIQUETA
- TELLO GARCIA ENRIQUETA
- Torrealba Suárez Isa
- Torrealba Suárez Isa
- VELASCO CAÑAS DIEGO FERNANDO
- VELASCO CAÑAS DIEGO FERNANDO
- VELAZQUEZ CIGARROA ERASMO
- VELAZQUEZ CIGARROA ERASMO
- VELAZQUEZ CIGARROA ERASMO
- VELAZQUEZ CIGARROA ERASMO
- VICTORINO RAMIREZ LIBERIO
- VICTORINO RAMIREZ LIBERIO
- Villa Monsalve Víctor Alexander
- Villa Monsalve Víctor Alexander
- Yera Toledo Raciel
- Yera Toledo Raciel
- ZAMORA LINARES RAFAEL
- ZAMORA LINARES RAFAEL
- Publication venue
- UAEMEX
- Publication date
- 01/01/2016
- Field of study
EL LIBRO PERMITE REFLEXIONAR SOBRE LA IMPORTANCIA DE FOMENTAL LA EDUCACIÓN AMBIENTAL PARA RESOLVER LA PROBLEMÁTICA AMBIENTALEL LIBRO PRESENTA DIFERENTES TRABAJOS QUE ESTUDIAN EL TEMA D ELA SUSTENTABILIDAD, ENFATIZANDO LA IMPORTANCIA DE LA EDUCACIÓN AMBIENTAL Y LA TRANSDISCIPLINANINGUN
Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.
- Author
- A. Abd El-Aziz
- A. Abdul
- A. Agakhanyan
- A. Aggarwala
- A. Agrawal
- A. Al Mulla
- A. Al Naeemi
- A. Alfieri
- A. Ali
- A. Altun
- A. Alvarez D'Amelio
- A. Andersson
- A. Argena
- A. Austria
- A. Aydinlar
- A. Babyesiza
- A. Barai
- A. Barreau
- A. Barszcz
- A. Bartes
- A. Bazzoni Ruiz
- A. Beattie
- A. Bianchi
- A. Biernacka
- A. Black
- A. Blenkhorn
- A. Branjovich Tijuan
- A. Bremmelgaard
- A. Brown
- A. Browne
- A. Capucci
- A. Caspar
- A. Catanchin
- A. Chmielowski
- A. Choi
- A. Cieszynska
- A. Conde Y Bolado
- A. Connelly
- A. Cortada Cabrera
- A. Davids
- A. De Blasio
- A. De Wolf
- A. Dickerson
- A. Domenech Borras
- A. Dumikyan
- A. Edin
- A. Egilsson
- A. El-Etreby
- A. Elbahry
- A. Elorriaga Madariaga
- A. Espallargas
- A. Ewert
- A. Fearon
- A. Fedorowsky
- A. Ferreira-Jardim
- A. Ferrer
- A. Filippi
- A. Fleck
- A. Flynn
- A. Forero
- A. Frankiewicz
- A. Fujisawa
- A. Gallagher
- A. Ganatra
- A. Gegenhuber
- A. Gieroba
- A. Gilliland
- A. Giombolini
- A. Gonzales Segovia
- A. Grande Ruiz
- A. Grau
- A. Grytzmann
- A. Gubanov
- A. Guerrero Molina
- A. Guinand
- A. Haideri
- A. Hajimirsadeghi
- A. Hallaråker
- A. Halpin
- A. Hay
- A. Heer
- A. Heyse
- A. Horak
- A. Hot-Bjelac
- A. Howitt
- A. Iglesias Garcia
- A. Ishihara
- A. Ivanov
- A. Iñiguez Romo
- A. Jackun-Podlesna
- A. Jaremczuk-Kaczmarczyk
- A. Jarzebowski
- A. Jefferies
- A. Jekthammer
- A. Jerzewski
- A. John Camm
- A. John Camm
- A. John Camm
- A. Jones
- A. Kaczmarzyk-Radka
- A. Karczmarczyk
- A. Katta
- A. Kemmel
- A. Khan
- A. Khokhlov
- A. Koch
- A. Kolesnikova
- A. Kolodzinska
- A. Komlo
- A. Konopka
- A. Kopf
- A. Krueger
- A. Krzesiak-Lodyga
- A. Lavoie
- A. Lawande
- A. Lee
- A. Lettenström
- A. Leyva Rendón
- A. Lindberg
- A. Lindh
- A. Lindourkova
- A. Lischka-Lindner
- A. Lo Buglio
- A. Lopes
- A. Lopez
- A. Lucassen
- A. Ludkova
- A. Lysek-Jozefowicz
- A. Mannermyr
- A. Manzanal Rey
- A. Mariani
- A. Markiewicz
- A. Marquand
- A. Martin Vila
- A. Martinelli
- A. Maselli
- A. Matoltsy
- A. Mauric
- A. Meirino
- A. Menezes Lorga Filho
- A. Merliss
- A. Metzgier-Gumiela
- A. Mielot
- A. Mirtl
- A. Miyashita
- A. Mizuno
- A. Mowafy
- A. Murray
- A. Naguib
- A. Nagy
- A. Nakagomi
- A. Nakata
- A. Navarro
- A. Negrete Palma
- A. Negri
- A. Niemirycz-Makurat
- A. Nowak
- A. Nygaard
- A. Ohanissian
- A. Ohlsson
- A. Olofsson
- A. Ortiz
- A. Osberg
- A. Ota
- A. Oto
- A. Ovsannikova
- A. Page
- A. Papp
- A. Parkhomenko
- A. Pawelska-Buczen
- A. Pedersen
- A. Phrommintikul
- A. Pinter
- A. Pizzini
- A. Plauskat
- A. Podczeck-Schweighofer
- A. Postolache
- A. Pronk
- A. Pustelnik
- A. Quick
- A. Quietzsch
- A. Quisi
- A. Raczynska
- A. Raisaro
- A. Ramdass
- A. Reda
- A. Rodrigues
- A. Ross
- A. Sabir
- A. Sage
- A. Said
- A. Salinas
- A. Sapatyi
- A. Sasaki
- A. Scaccianoce
- A. Seoane Blanco
- A. Sidor
- A. Singal
- A. Skein
- A. Soliman
- A. Soma
- A. Sossich
- A. Spyropoulos
- A. Srinivas
- A. Sriwichian
- A. Stallinga-de Vos
- A. Steffens
- A. Suissa
- A. Sulc
- A. Svilaas
- A. Sword
- A. Szczepanska
- A. Szilagyi
- A. Szulowska
- A. Taguchi
- A. Talkenberger
- A. Tangsirira
- A. Tetlak
- A. Thatcher
- A. Therkelsen
- A. Thomson
- A. Tomasello
- A. Ushakov
- A. Vandorpe
- A. Vertes
- A. Vishnevsky
- A. Vonbank
- A. Wakeman
- A. Waldman
- A. Warke
- A. Wassef
- A. Wierzbicka
- A. Williams
- A. Wilson
- A. Wirdby
- A. Wutthimanop
- A. Yagensky
- A. Yoshimura
- A. Zateyshchikova
- A. Østrem
- A.-B. Ekstrand
- A.-K. Ascoop
- A.-M. Barbuto
- A.-M. Ohlin
- A.A. Damonte
- A.A. Fernandez
- A.B. Lensebraaten
- A.C. Billiaux
- A.C. Ingaramo
- A.C. Rothwell
- A.C. Tovar Castaneda
- A.C.P. Barretto
- A.D. Hrabar
- A.G. Ravi Shankar
- A.J. Kleiban
- A.J. McLeod
- A.L. Baek
- A.L. Cappi
- A.L. Tufare
- A.M. Jackson
- A.P. Drummond Wainstein
- A.P. Macagnan
- A.R. Kelsall
- A.R. Park
- A.S. Pandey
- Ajay K. Kakkar
- Ajay K. Kakkar
- Alex Parkhomenko
- Alex Spyropoulos
- Alexander G.G. Turpie
- Ali Oto
- Antonio Carlos Pereira Barretto
- B. Allasia
- B. Alzand
- B. Ayres
- B. Chatlaong
- B. Clarke
- B. Conway
- B. Coutu
- B. Crousillat
- B. Curyllo
- B. Deshpande
- B. Dolecka
- B. Doucet
- B. Dubois
- B. Dudzik-Richter
- B. Eriksson
- B. Fox
- B. Gaszner
- B. Ghezai
- B. Gosciniecka
- B. Hawkins
- B. Herrero Maeso
- B. Hoffmann
- B. Ikitimur
- B. Jacobson
- B. Jacobson
- B. Jansson
- B. Jimeno Besa
- B. Kurylo
- B. Kurylo
- B. Li
- B. Liu
- B. Lokesh
- B. Martinsson
- B. Mautner
- B. Merkely
- B. Mooso
- B. Naratreekoon
- B. Okopien
- B. Opielowska-Nowak
- B. Ostrowska-Pomian
- B. Racz
- B. Raghuraman
- B. Ramjattan
- B. Rzyczkowska
- B. Sarai
- B. Schaefer
- B. Schneeweiß
- B. Schweitzer
- B. Sievers
- B. Silaruks
- B. Singh
- B. Sinha
- B. Stephanie
- B. Strohmer
- B. Subbaraman
- B. Unterkircher
- B. Uppelschoten
- B. Vandrus
- B. Vanhauwaert
- B. Vishwanathan
- B. Vogel
- B. Voigts
- B. Ward
- B. Wollaert
- B. Wozakowska-Kaplon
- B. Zhou
- B.-T. Kellner
- B.A.J. Stockins Fernandez
- B.C. Jung
- B.E. Groenemeijer
- B.R. Park
- B.Y. Sayin
- Barry Jacobson
- Bernard J. Gersh
- C. A'Court
- C. Arabetti
- C. Astudillo
- C. Axthelm
- C. Batta
- C. Beltra
- C. Bergeron
- C. Bergeron
- C. Bester
- C. Boshoff
- C. Bothin
- C. Bouvy
- C. Bradshaw
- C. Brike
- C. Brotons Cuixart
- C. Bugueño Gutiérrez
- C. Buiks
- C. Bulla
- C. Buzzetti
- C. Cannon
- C. Cantú Brito
- C. Chami
- C. Chigbo
- C. Ciabatta
- C. Conejeros
- C. Correa
- C. Corros Vicente
- C. Costantini Ortiz
- C. D'Arienzo
- C. Dias
- C. Dooldeniya
- C. Díaz de la Vega
- C. Ellervik
- C. Femiano
- C. Fonseca
- C. Fritz
- C. Funosas
- C. Giles
- C. Gines Garcia
- C. Gomez
- C. Grässjö
- C. Guldener
- C. Gómez Pajuelo
- C. Hagn
- C. Hawkins
- C. Hernández Herrera
- C. Herrick
- C. Hines
- C. Houzvic
- C. Hutton
- C. Jacobs
- C. Jean
- C. Juergens
- C. Kongsin
- C. Lara
- C. Latella
- C. Lewis
- C. Liley
- C. Lodigiani
- C. Martinelli
- C. Mazzone
- C. McCarthy
- C. McIntosh
- C. Moncada
- C. Moro Serrano
- C. Mulholland
- C. Munhoz da Fontoura Tavares
- C. Mussap
- C. Nanzer Vital
- C. Nilsson
- C. Ogurusu
- C. Ormundo
- C. Orosco
- C. Ortiz Cortes
- C. Paul
- C. Pisani
- C. Queirantes
- C. Ramesh
- C. Ravenhorst
- C. Reichelt
- C. Reimer
- C. Rey
- C. Richard
- C. Ricotti
- C. Rivera Ramos
- C. Robertson
- C. Roca Saumell
- C. Rodrigo
- C. Santolaya
- C. Scarone
- C. Scheurwegs
- C. Schubert
- C. Schwencke
- C. Seamark
- C. Simon Valero
- C. Singh
- C. Singleton
- C. Smessaert
- C. Stoll
- C. Stöcklöcker
- C. Sugimoto
- C. Takanaka
- C. Thorsen
- C. Tondo
- C. Torres
- C. Treasure
- C. Vantomme
- C. Verdi
- C. Vicente
- C. Villan
- C. Wöhrer
- C. Yeo
- C. Zecca
- C.-J. Kim
- C.-J. Lindholm
- C.A. Almeida Fernández
- C.A. Neden
- C.C. Broilo França
- C.G. Foo
- C.H. Del Carlo
- C.H. Gimenez
- C.J. Sánchez Díaz
- C.K. Ching
- C.L. Bai
- C.L. Gonzalez Garcia
- C.M. Diaz Lopez
- C.P. Jones
- C.R. Costantini Frack
- C.R. Frack Costantini
- C.S. Lee
- Carlos Jerjes Sánchez Díaz
- Carmela Alonso
- Concepcion Alonso
- D. Adak
- D. Alpay
- D. Alvarez
- D. Amstutz
- D. Andrzejewski
- D. Aras
- D. Armaganijan
- D. Atar
- D. Belenky
- D. Bertolim Precoma
- D. Blaszczyk
- D. Buckert
- D. Cassidy
- D. Castro Fernandez
- D. Chemello
- D. Cholsaringkarl
- D. Colquhoun
- D. Conde
- D. Coulshed
- D. Cresp
- D. Crimmins
- D. Davies
- D. De Cleen
- D. Denie
- D. Diercks
- D. Eccleston
- D. Edwards
- D. Faes
- D. Farquhar
- D. Fielder
- D. Fitzmaurice
- D. Fitzpatrick
- D. Flores Martínez
- D. Fournier
- D. Galley
- D. Geatch
- D. Genc
- D. Glatzel
- D. Goodwin
- D. Gray
- D. Greyling
- D. Guanaes
- D. Guedj-Meynier
- D. Gulyas
- D. Ikeda
- D. Jackson
- D. Jain
- D. Kernick
- D. Kettles
- D. Kociolek
- D. Komar
- D. Konyushenko
- D. Kroll
- D. Kruczyk
- D. Kusiak
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- S. Tereshchenko
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- S.-H. Kim
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- S.A. Jensen
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- S.E. Lee
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- S.R. Jeon
- S.W. Hwang
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- S.W. Wong
- S.Y. Yap
- S.Y. Yun
- S.Z. Goldhaber
- Samuel Z. Goldhaber
- Samuel Z. Goldhaber
- Samuel Z. Goldhaber
- Sang Hee Kim
- Sang Hyun Kim
- Sanjay Kakkar
- Seil Oh
- Sen Adachi
- Shinya Goto
- Sho Nagai
- Shu Suzuki
- Shunichi Nagai
- Shunji Suzuki
- Stuart J. Connolly
- Susumu Adachi
- Susumu Suzuki
- Sylvia Haas
- Sylvia Haas
- T. Adachi
- T. Amano
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- T. Arino
- T. Asano
- T. Aves
- T. Baba
- T. Bang-Hansen
- T. Barbosa
- T. Betsuyaku
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- T. Bunyapipat
- T. Casier
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- T. Da Rocha Rodrigues
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- T. Eykerman
- T. Fetahovic
- T. Fooks
- T. Fudo
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- T. Furukawa
- T. Félix Lorenzato Fonseca
- T. Gooding
- T. Gorshkova
- T. Goto
- T. Grabek
- T. Gutowski
- T. Habon
- T. Harbour
- T. Hatsuno
- T. Hicks
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- T. Ido
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- T. Izquierdo
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- T. Kito
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- T. Kolesova
- T. Kotani
- T. Koyanagi
- T. Kozuka
- T. Kumazaki
- T. Kupriyanova
- T. Kusumoto
- T. Kuwahata
- T. Laksomya
- T. Lincoln
- T. Loekkegaard
- T. Läßig
- T. Mark
- T. Medvedeva
- T. Minagawa
- T. Mita
- T. Mito
- T. Mori
- T. Mueller
- T. Murayama
- T. Myhill
- T. Nagatomo
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- T. Nanke
- T. Novikova
- T. Ogawa
- T. Ono
- T. Ovdiienko
- T. Parrott
- T. Patching
- T. Phan
- T. Pillay
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- T. Richardson
- T. Ripoll Vera
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- T. Rusicka-Piekarz
- T. Saito
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- T. Schatzberger
- T. Schwarz
- T. Schäfer
- T. Seker
- T. Seo
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- T. Shindo
- T. Shinozuka
- T. Shirai
- T. Shiraiwa
- T. Stephenson
- T. Suetsugu
- T. Suga
- T. Suttana
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- T. Tana
- T. Taniguchi
- T. Tau
- T. Toennishoff
- T. Traczyk
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- T. Tripti
- T. Tsuji
- T. Ueda
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- T. Unoki
- T. van der Kley
- T. Vargas
- T. Vasankari
- T. Viana
- T. Vydt
- T. Wakiyama
- T. Washizuka
- T. Weyn
- T. Wisaratapong
- T. Wolf
- T. Wong
- T. Yamada
- T. Yamagishi
- T. Yamamoto
- T. Yu
- T. Øien
- T.-J. Cha
- T.A.A. Alfaro
- T.G. Wu
- T.J. Hong
- T.M. Caimi
- T.T. Liu
- T.W. Lim
- T.Y. Ma
- Tadashi Nakamura
- Tetsuro Yoshida
- Tomoki Yoshida
- Toon Wei Lim
- Tsugihiro Nakamura
- U. Börjesson
- U. Dichristin
- U. Gerbaulet
- U. Hintze
- U. Horstmeier
- U. Kitmapawanont
- U. Weiser
- U.M. Nagamalesh
- V. Araujo
- V. Becerra Munoz
- V. Biagioli
- V. Bisne
- V. Campisi
- V. Dedek
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- V. Durdil
- V. Eissing
- V. Eltishcheva
- V. Fernandez Caputi
- V. Garcia Millan
- V. Hansen
- V. Hubacova
- V. Jain
- V. Klein
- V. Korley
- V. Kostenko
- V. Lawlor
- V. Lilienweiß
- V. Machova
- V. Mitrovic
- V. Mochonyi
- V. Nagalingam
- V. Navarre
- V. Nemtsova
- V. Nilsen
- V. Novas
- V. O'May
- V. Olguin
- V. Oriana
- V. Palumbo
- V. Pannacci
- V. Paul
- V. Pengo
- V. Piamonte
- V. Quintern
- V. Rasanen
- V. Rios
- V. Roa Castro
- V. St Joseph
- V. Thyssen
- V. Tseluyko
- V. Ueckermann
- V. Vanajakshamma
- V. Varenov
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- V.A. Sinisi
- V.L. Pereira
- V.M. Ortega
- V.M. Vijan
- Veerappa A. Kothiwale
- Velam Vanajakshamma
- Vikas Bisne
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- W. Ahmed
- W. Al Mahmeed
- W. Anné
- W. Boonyapisit
- W. Brzozowski
- W. Coulson
- W. Dorsch
- W. Eder
- W. Erdle
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- W. Haverkamp
- W. Hermans
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- W. Kurdzielewicz
- W. Lang
- W. Lumb
- W. Murdoch
- W. Myszka
- W. Oosthuysen
- W. Rogowski
- W. Smolders
- W. Suebjaksing
- W. Supinski
- W. Szkrobka
- W. Terpstra
- W. Tiyanon
- W. Van Gaal
- W. Wieczorek
- W. Wildenauer
- W. Willcock
- W. Wongcharoen
- W. Wongtheptien
- W.H. Li
- W.J. Chi
- W.L. Liu
- W.M. Kutayli
- W.N. Guo
- W.S. Son
- W.T. Lim
- W.Y. Lee
- W.Y. Zheng
- Wael Al Mahmeed
- Werner Hacke
- X. Chen
- X. Giry
- X. Li
- X. Robiro Robiro
- X. Sheng
- X. Vandamme
- X. Viñolas
- X.A. He
- X.F. Huang
- X.J. Gao
- X.J. Shi
- X.L. Luo
- X.S. Cheng
- X.S. Hu
- X.W. Yan
- X.Y. Zhu
- Xavier Viñolas
- Y. Abe
- Y. Atsuchi
- Y. Balthazar
- Y. Belenkova
- Y. Campisto
- Y. Emura
- Y. Fujii
- Y. Fujisawa
- Y. Go
- Y. Gomez Perez
- Y. Gottwalles
- Y. Guo
- Y. Haraguchi
- Y. Hata
- Y. Hatori
- Y. Hayashi
- Y. Ivanova
- Y. Jiao
- Y. Kamogawa
- Y. Kato
- Y. Katsube
- Y. Katsuda
- Y. Kawada
- Y. Kelfkens
- Y. Kitami
- Y. Koretsune
- Y. Koshibu
- Y. Kumai
- Y. Maruyama
- Y. Matsuura
- Y. Mizuno
- Y. Moiseeva
- Y. Mostovoy
- Y. Niijima
- Y. Nishida
- Y. Nishihata
- Y. Oba
- Y. Onuki Pearce
- Y. Orlov
- Y. Osmolovskaya
- Y. Park
- Y. Saito
- Y. Sakamoto
- Y. Samejima
- Y. Santanakorn
- Y. Sasagawa
- Y. Sekine
- Y. Seta
- Y. Shapovalova
- Y. Shiina
- Y. Shimoyama
- Y. Shozawa
- Y. Stipp
- Y. Suzuki
- Y. Svyshchenko
- Y. Takagi
- Y. Tsuchiya
- Y. Ueyama
- Y. Vandekerckhove
- Y. Vorasettakarnkij
- Y. Wakasa
- Y. Ye
- Y. Yokoyama
- Y. Zhang
- Y.-I. Kim
- Y.H. Li
- Y.H. Sun
- Y.H. Yin
- Y.J. Yang
- Y.J. Yang
- Y.K. On
- Y.M. Chen
- Y.M. Lee
- Y.M. Sohn
- Y.R. Jeon
- Y.S. Oh
- Y.S. Son
- Y.S. Zhao
- Y.Y. Liu
- Ying Wang
- Yoichi Nakamura
- Yong Wang
- Yoshihisa Fujiura
- Yoshitake Fujiura
- Yuhei Shiga
- Yuichiro Nakamura
- Yukihiro Koretsune
- Yukio Shiga
- Z. Babjakova
- Z. Boda
- Z. Djaidani
- Z. Lajkowski
- Z. Laszlo
- Z. May
- Z. Monhart
- Z. Ongen
- Z. Radics
- Z.C. Lu
- Z.H. Zhou
- Z.M. Yang
- Publication venue
- Indian Heart J
- Publication date
- 01/01/2018
- Field of study
BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362
The STARMEN trial indicates that alternating treatment with corticosteroids and cyclophosphamide is superior to sequential treatment with tacrolimus and rituximab in primary membranous nephropathy
- Author
- Agraz Irene
- Avila Ana
- Bonet Jose
- Cabello Virginia
- Cao Mercedes
- Caravaca-Fontan Fernando
- Diez Montserrat
- Egido Jesus
- Espinosa Mario
- Fernandez-Juarez Gema
- Galeano Cristina
- Goicoechea Diezhandino Marian
- Justino Joana
- Lambeau Gerard
- Malek Thomas
- Martin-Reyes Guillermo
- Plaisier Emmanuelle
- Praga Manuel
- Quintana Luis F.
- Rabasco Cristina
- Ramon Gomez-Martino Juan
- Rivas Begona
- Rodriguez-Moreno Antolina
- Rojas-Rivera Jorge
- Romera Ana
- Ronco Pierre
- Segarra Alfonso
- Sevillano Angel
- Shabaka Amir
- STARMEN Investigators
- van de Logt Anne-Els
- Varela Alfonso
- Wetzels Jack
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2021
- Field of study
A cyclical corticosteroid-cyclophosphamide regimen is recommended for patients with primary membranous nephropathy at high risk of progression. We hypothesized that sequential therapy with tacrolimus and rituximab is superior to cyclical alternating treatment with corticosteroids and cyclophosphamide in inducing persistent remission in these patients. This was tested in a randomized, open-label controlled trial of 86 patients with primary membranous nephropathy and persistent nephrotic syndrome after six-months observation and assigned 43 each to receive six-month cyclical treatment with corticosteroid and cyclophosphamide or sequential treatment with tacrolimus (full-dose for six months and tapering for another three months) and rituximab (one gram at month six). The primary outcome was complete or partial remission of nephrotic syndrome at 24 months. This composite outcome occurred in 36 patients (83.7%) in the corticosteroid-cyclophosphamide group and in 25 patients (58.1%) in the tacrolimus-rituximab group (relative risk 1.44; 95% confidence interval 1.08 to 1.92). Complete remission at 24 months occurred in 26 patients (60%) in the corticosteroid-cyclophosphamide group and in 11 patients (26%) in the tacrolimus-rituximab group (2.36; 1.34 to 4.16). Anti-PLA2R titers showed a significant decrease in both groups but the proportion of anti-PLA2R-positive patients who achieved immunological response (depletion of anti-PLA2R antibodies) was significantly higher at three and six months in the corticosteroid-cyclophosphamide group (77% and 92%, respectively), as compared to the tacrolimus-rituximab group (45% and 70%, respectively). Relapses occurred in one patient in the corticosteroid-cyclophosphamide group, and three patients in the tacrolimus-rituximab group. Serious adverse events were similar in both groups. Thus, treatment with corticosteroid-cyclophosphamide induced remission in a significantly greater number of patients with primary membranous nephropathy than tacrolimus-rituximab
Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study
- Author
- Ababneh Hazim
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abbo Olivier
- Abbott Tom
- Abd Elwahab Sami
- Abdelkabir Mohammed
- Abdelkhalek Mohamed
- Abdur-Rahman Lukman
- Abebe Metasebia
- Aboazamazem Hajir
- Abou Chaar Mohamad K.
- Abou Chaar Mohamad K.
- Abouelnagah Galal
- Abozied Hesham
- Abu Salhiyeh Ala'a
- Abu-Ismail Luai
- Abu-Mehsen Marah
- Abukhalaf Sadi A.
- Abuleil Amro
- Achalandabaso Boira Mar
- Ackermann Travis
- Acquah Daniel Kwesi
- Adam Mohammed Elmujtba Adam Essa
- Adamina Michel
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adisa Adewale
- Afolabi Akinwale
- Agarwal Arnav
- Agarwal Gaurav
- Agastra Ervis
- Agbadebo Mouhamed
- Agbonrofo Peter
- Aguiar Junior Samuel
- Aguilera-Arevalo Maria-Lorena
- Ahmad Amer
- Ahmad Siddique
- Ahmed Waheed-Ul-Rahman
- Aigner Felix
- Akhavizadegan Hamed
- Akhbari Melika
- Akililu Yemisirach Bizuneh
- Akinmade Akinola
- Al Ameer Ahmed
- Al Amri Abdulrahman
- Al Balushi Zainab
- Al Maadany Faraj
- Al-Manaseer Balqees Mahmoud
- Al-Naggar Hamza
- Aladawi Omar
- Alajalen Amer
- Alalawi Yousef
- Alameer Ehab
- Alansari Arowa Hassan Abdulrahman
- Alawami Mohammed
- Alawneh Yazan
- Alayan Mohammed
- Alberdi San Roman Igor
- Albertsmeier Markus
- Alcaraz Fuentes Marta
- Alderazi Amer
- Aldressi Wafa
- Alexander Philip
- AlFakhri Abdullah
- Alharthi Mohammed
- Alhefdhi Amal
- Alkadeeki Ghadah
- Alkaseek Akram
- Alkhatib Ahmad
- Almabayev Ydyrys
- Almeida-Reis Rui
- Almiqlash Bushray
- Almoguera Jorge
- Almugaddami Ayman
- Almulhim Abddulrahman Saleh
- Alonso Mendoza Veronica
- Alqudah Majdi Ali
- Alrayes Bourhan
- Alsaadi Hayder
- Alser Osaid
- Alshaar Muhammad
- Alshahrani Mushabab
- Alshareef Khayriyah
- Alshehri Ameen
- Alshryda Sattar
- Alsibai Sareyah
- Alsunna Zaid
- Altaf Humera Naz
- Althumairi Azah
- Althumairi Azah
- Alyami Mohammad
- Alzahrani Abdulrahman
- Alzaidi Turki M.
- Alzerwi Nasser
- Amisi Nicolas
- Amnaina Mohamed
- Andre Benoit
- Andres Calvache Jose
- Angeles Martina Aida
- Anwer Mariyah
- Anyanwu Lofty-John
- Aqeelah Ahmed
- Aqil Sabra
- Arevalo Sandoval Danilo Alfonso
- Argus Leah
- Arias Claudia
- Arnalsteen Laurent
- Arnaud Alexis P.
- Asif Muhammad
- Assefa Melatework
- Ataide Gomes Gustavo Mendonca
- Atnafu Bahru
- Aviles Jimenez Pablo Mijahil
- Awad Selmy
- Ayasra Faris
- Ayoub Abdu
- Ayub Bushra
- Azevedo Jose
- Azevedo Jose
- Azevedo Pedro
- Aziz Aliya
- Azzam Ahmed Y.
- Bacalbasa Nicolae
- Badareesh L.
- Badenes Rafael
- Badiani Sarit
- Baia Catarina
- Bains Lovenish
- Baiocchi Glauco
- Bajaj Ankur
- Balanta-Melo Julian
- Baliarsing Lipika
- Ball Alasdair
- Ballouhey Quentin
- Bankhead-Kendall Brittany
- Barillas Sabrina
- Barker John
- Barrena Lopez Cristina
- Barros Aldo Vieira
- Basu Somprakas
- Batista Sylvia
- Behzadi Abdollah
- Bekele Kebebe
- Bele Uros
- Bele Uros
- Bella Romera Susana
- Ben Amer Anass
- Ben Jouira Rayet al Islam
- Benson Ruth
- Bergeat Damien
- Bertrand Marta
- Bescos Coro
- Betalleluz Pallardel Jenner
- Bezabih Yoseph Solomon
- Bhanderi Shivam
- Bhangu Aneel
- Bhat Dhananjaya
- Bhatti Abu Bakar Hafeez
- Bhende Vishal
- Biccard Bruce
- Blanco-Colino Ruth
- Boccalatte Luis
- Boisson Matthieu
- Bolatbekova Raikhan
- Bolger Jarlath
- Bolivar Saenz Dinimo
- Bonci Eduard-Alexandru
- Borda-Luque Giuliano
- Borges Filipe Castro
- Bork Ulrich
- Borowski David W.
- Bouche Pierre-Alban
- Boucher Sophie
- Bouhuwaish Ahmad
- Branquinho Rita
- Brar Amanpreet
- Breen Kerry
- Bright Tim
- Brown Wendy
- Brunaud Laurent
- Brunner Stefan M.
- Buarque Igor
- Buarque Igor Lima
- Bucyibaruta Georges
- Bukhari Syed Imran
- Burgan Dania
- Butyrskii Aleksandr
- Bwala Kefas
- Bywater Edward P.
- Cabanero Sanchez Alberto
- Caiado Andre
- Caicedo Lina
- Caja Vivancos Patricia
- Cal Fernando Bonilla
- Calderon Arancibia Jose Alfredo
- Calvo Espino Pablo
- Canals Sin Ma Pilar
- Canno Velasco Jorge
- Cappeliez Serge
- Cardenas Puiggros Laura
- Cardoso Paulo
- Carlos Bernal-Sprekelsen Juan
- Carpio Colmenares Yahaira Tatiana
- Carrasco Prats Milagros
- Carrera Jacqueline
- Carreras-Castaner Anna
- Caruana Edward
- Castell Gomez Jose Tomas
- Catala Bauset Juan Carlos
- Cerovac Anis
- Chadi Sami
- Chakrabortee Sohini
- Chapatwala Reema
- Charbonneau Helene
- Charles Shane
- Chaudhary Muhammad Hamid
- Chaudhry Daoud
- Chaudhry Navneet Kumar
- Chebaro Alexandre
- Chew Min Hoe
- Choong Peter
- Chowdappa Raghunandan Gorantlu
- Chowdhury Sharfuddin
- Christensen Peter
- Chuan Alwin
- Chwat Carina
- Clancy Cillian
- Colas-Ruiz Enrique
- Connelly Tara
- Connor Clare O.
- Corella Fernando
- Corripio-Sanchez Ramon
- Costa Luciana Cidade
- Costas-Chavarri Ainhoa
- Costea Radu
- Cox Daniel
- Creavin Ben
- Crego Vita Diana
- Cretolle Celia
- Cristina Rahy-Martin Aida
- Croghan Stefanie M.
- Cukier Moises
- Cullinane Carolyn
- Cunha Miguel F.
- D'Aulerio Giuliana
- Dajti Irida
- Daoud Hassan
- Davis Niall
- Dawson Amanda Caroline
- Dawson Brett E.
- De Andres-Asenjo Beatriz
- de Dieu Haragirimana Jean
- De Simone Belinda
- Degefa Eyueal
- Delgado Fernandez Juan
- Delibegovic Samir
- Delisau-Puig Olga
- Dell Angela
- Demetrashvili Zaza
- Demetriades Andreas K.
- Derilo Habtamu
- des Deserts Marc Danguy
- Desai Anant
- Deus Ana Claudia
- Dharap Satish
- Dhondt Bert
- Dhufera Hailu
- Di Martino Marcello
- Di Saverio Salomone
- Diaz Martinez Eneida
- Diaz-Feijoo Berta
- Diego Garcia Lucia
- Diez Alonso Manuel
- Dimofte Mihail-Gabriel
- Dione Sacdalan Marie
- do Amaral Campos Heloisa Galvao
- Doerner Johannes
- Domenech Julio
- Donlon Noel
- Drake Thomas
- Drasovean Radu
- Duarte Amalia Barrios
- Dube Surya Kumar
- Duchalais Emilie
- Dudi-Venkata Nagendra
- Duprat Neto Joao Pedreira
- Duran Sanchez Iran Irani
- Duran Irani
- Duro Agustin
- Dwaga Sumayya Essayah
- Dziakova Jana
- Earley Helen
- Eberbach Helge
- Edwards John
- Efetov Sergey
- Efetov Sergey
- Egoroff Natasha
- Ekenze Sebastian
- Ekiti Ido
- El-Boghdadly Kariem
- El-Hussuna Alaa
- Elhadi Muhammed
- Elhadi Muhammed
- Elhajdawe Fras
- Elliott Brodie
- Ellojli Ibrahim
- Emile Sameh
- Enjuto Diego
- Escudero Mario I.
- Eskander Antoine
- Espin-Basany Eloy
- Espinosa-Bravo Martin
- Estaire Gomez Mercedes
- Evans Jonathan
- Evelyn R Nissi
- Ezanno Anne-Cecile
- Fahadullah Muhammad
- Fahmy Mohamed
- Fakhradiyev Ildar
- Falcon Pacheco Glenda Marina
- Farfus Anthony
- Farik Shebani
- Farooq Umer
- Faustin Ntirenganya
- Fernandez Coimbra Felipe Jose
- Fernandez Martin Maria Teresa
- Fernandez Martinez Daniel
- Fernandez-Lopez Antonio-Jose
- Figueroa-Casanova Rafael
- Filipce Venko
- Filipescu Daniela
- Fiore Marco
- Fisseha Tigist
- Flamey Nicolas
- Fleming Christina
- Flexman Alana
- Fluegen Georg
- Flumignan Ronald
- Ford Samuel
- Forero-Torres Alexander
- Fotopoulou Christina
- Fowler Alexander
- Fredon Fabien
- Freiria Eiras Miguel Angel
- Fuentes Tyare
- Fujimoto Yuki
- Futaba Kaori
- Gahwagi Milad
- Gallo Gaetano
- Ganly Ian
- Garcia De Cortazar Unai
- Garcia Escudero Damian
- Garcia Laura Saura
- Garcia Soria Vanesa
- Garcia-Adamez Jorge
- Garcia-Montoya Oscar-Julian
- Gaujoux Sebastien
- Gavalda Pellice M. Teresa
- Gebreyohanes Mengistu
- Gempt Jens
- Ghazwani Salman
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- Kroon Hidde M.
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- Zhou Xuanyu
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- Zimmelman Natalie
- Zmora Oded
- Zmora Oded
- Publication venue
- Publication date
- 01/01/2021
- Field of study
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- Ababneh Hazim
- Abad-Motos Ane
- Abbas Ferial Mohamed Ali
- Abbo Olivier
- Abbott Tom
- Abbott Tom
- Abdelkabir Mohammed
- Abdelkhalek Mohamed
- Abdoun Meriem
- Abdur-Rahman Lukman
- Abdur-Rahman Lukman
- Abebe Metasebia
- Aboazamazem Hajir
- Abou Chaar Mohamad K.
- Abou Chaar Mohamad K.
- Abouelnagah Galal
- Abozied Hesham
- Abu Salhiyeh Ala A.
- Abu-Ismail Luai
- Abu-Mehsen Marah
- Abuawad Carla
- Abukhalaf Sadi A.
- Abuleil Amro
- Ackermann Travis
- Acquah Daniel Kwesi
- Adam Mohammed Elmujtba Adam Essa
- Adamina Michel
- Adamina Michel
- Ademuyiwa Adesoji
- Adesanya Opeoluwa
- Adisa Adewale
- Adisa Adewale
- Afolabi Akinwale
- Agarwal Arnav
- Agarwal Gaurav
- Agarwal Ketan
- Agastra Ervis
- Agastra Ervis
- Agbadebo Mouhamed
- Agbonrofo Peter
- Aguilera-Arevalo Maria-Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahmad Amer
- Ahmad Siddique
- Ahmadi Navid
- Ahmed Waheed-Ul-Rahman
- Aigner Felix
- Aiken Taylor
- Akhavizadegan Hamed
- Akhbari Melika
- Akililu Yemisirach Bizuneh
- Akinmade Akinola
- Al Ameer Ahmed
- Al Ameer Ahmed
- Al Amri Abdulrahman
- Al Balushi Zainab
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- Al Maadany Faraj
- Al-Manaseer Balqees Mahmoud
- Al-Naggar Hamza
- Al-Naggar Hamza
- Al-Raimi Ibrahim
- Al-Sabbagh Yusra
- Al-Shehari Mohammed
- Aladawi Omar
- Alajalen Amer
- Alalawi Yousef
- AlAmeer Ehab
- Alameer Ehab
- Alansari Arowa Hassan Abdulrahman
- Alawami Mohammed
- Alawneh Yazan
- Alayan Mohammed
- Albared Sara Maa
- Albertsmeier Markus
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- Alderazi Amer
- Aldlyami Ehab
- Aldressi Wafa
- Alecci Anna
- Alexander Philip
- AlFakhri Abdullah
- Alharthi Mohammed
- Alhassoun Turki
- Alhefdhi Amal
- Alkadeeki Ghadah
- Alkaseek Akram
- Alkhatib Ahmad
- Allemand Carola
- Almabayev Ydyrys
- Almeida-Reis Rui
- Almiqlash Bushray
- Almoguera Jorge
- Almugaddami Ayman
- Almulhim Abddulrahman Saleh
- Alnachoukati Omar
- Alnahr Hareth
- Alonso Jesús Aarón Martínez
- Alonso Manuel Diez
- Alonso Nestor Fabian Pedraza
- Alqudah Majdi Ali
- Alrayes Bourhan
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- Alser Osaid
- Alshaar Muhammad
- Alshahrani Mushabab
- Alshareef Khayriyah
- Alshehri Ameen
- Alshryda Sattar
- Alshryda Sattar
- Alsibai Sareyah
- Alsunna Zaid
- Altaf Humera Naz
- Althumairi Azah
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- Althumairi Azah
- Alvarado Carlos Eduardo Otiniano
- Alyami Mohammad
- Alzahrani Abdulrahman
- Alzaidi Turki M.
- Alzate Juan Pablo
- Alzerwi Nasser
- Amisi Nicolas
- Amnaina Mohamed
- Amor María Sol Crespi
- André Benoît
- Angeles Martina Aida
- Anwer Mariyah
- Anyanwu Lofty-John
- Aouabed Nesrine
- Aqeelah Ahmed
- Aqil Sabra
- Arancibia José Alfredo Calderón
- Arango Maria Clara Mendoza
- Arbane Gill
- Argus Leah
- Arias Claudia
- Arnalsteen Laurent
- Arnaud Alexis P.
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- Asif Muhammad
- Assefa Melatework
- Atnafu Bahru
- Aulerio Giuliana D.
- Aurora
- Awad Selmy
- Ayasra Faris
- Ayasra Faris
- Ayoub Abdu
- Ayub Bushra
- Ayub Khurram
- Azevedo José
- Azevedo José
- Azevedo Pedro
- Aziz Aliya
- Azzam Ahmed Y.
- Bacalbasa Nicolae
- Badareesh L.
- Badenes Rafael
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- Balasubramanya Supriya
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- Bastet Joaquin
- Basu Somprakas
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- Bekele Kebebe
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- Bezabih Yoseph Solomon
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- Bhat Dhananjaya
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- Bhende Vishal
- Bhutiani Neal
- Bianco Agustín
- Biccard Bruce
- Blanco-Colino Ruth
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- Blasco Laura Sánchez
- Boccalatte Luis
- Boccalatte Luis
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- Boira Mar Achalandabaso
- Boisson Matthieu
- Bolatbekova Raikhan
- Bolger Jarlath
- Bollano Enton
- Bonci Eduard-Alexandru
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- Borda-Luque Giuliano
- Boretto Jorge G.
- Borges Filipe Castro
- Bork Ulrich
- Borowski David W.
- Botero Marcela Velez
- Bouaoud Souad
- Bouche Pierre-Alban
- Bouchenak Kamel
- Boucher Sophie
- Boudou Rocio
- Bouhuwaish Ahmad
- Brandariz Rodrigo
- Branquinho Rita
- Brar Amanpreet
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- Bravo Ana Maria Minaya
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- Breen Kerry
- Brennan Caitlin
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- Bright Tim
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- Brunaud Laurent
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- Buarque Igor Lima
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- Costea Radu
- Cotta Estefanía
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- Vaysburg Dennis
- Vaysse Charlotte
- Velasco Jorge Caño
- Velasquez Enrique Jose Ruiz
- Venkatappa Sunil Kumar
- Venn Mary L.
- Verhaeghe Romain
- Verhaeghe Romain
- Vidal Rafael Perez
- Vidya Raghavan
- Vijayakumar Vijayakumar M.
- Villanueva Julio
- Vimalakanthan Thanusan
- Vita Diana Crego
- Vivancos Patricia Caja
- Viveiros Octavio
- Vives Inmaculada
- Vives Josep Maria Muñoz
- Vo Uyen Giao
- von Pusch Silke
- Vrapi Enxhi
- Vázquez Irene Ortega
- Wafi Omar
- Wagner Arthur
- Waissbluth Sofia
- Waqar Shahzad Hussain
- Watson David
- Watson Eleanor
- Watters David
- Weeraddana Prabuth Dulanjan
- Wells Cameron
- Welter Stefan
- Wettstein Dániel
- Wickramasinghe Dakshitha
- Wickramasinghe Dakshitha
- Wiegering Armin
- Wijeysundera Duminda
- Williams Emmanuel
- Williams Omolara
- Williams Omolara
- Wilson Michael
- Wolf Sebastian
- Wolfer Susanne
- Wong Enoch
- Wright Deborah
- Wright Deborah
- Wright Naomi
- Wuraola Funmilola
- Wuraola Funmilola
- Xaviour Okedi Francis
- Xu William
- Yadev I.
- Yagoub Ghozlan
- Yaqoob Eesha
- Yaqoob Hassan Nawaz
- Yasin Seid Mohammed
- Yazbek Guilherme
- Yebes Alvaro
- Yeung Justin
- Yip Sebastian Shu
- Youssef Mina
- Zabaleta Jon
- Zahid Imdad Ahmad
- Zanoni Gerardo
- Zapardiel Ignacio
- Zapata Carlos Shiraishi
- Zarnescu Narcis Octavian
- Zarour Ahmad
- Zarour Ahmad
- Zarour Ahmad
- Zarratea Celeste Soledad
- Zegarra Sergio
- Zequi Stenio C.
- Zezular Damaris Idara Anabel
- Zhou Xuanyu
- Zhussupov Baurzhan
- Zijaj Lorena
- Zimmelman Natalie
- Zmora Oded
- Zmora Oded
- Zohra Belabbes Fatima
- Publication venue
- HAL CCSD
- Publication date
- 01/11/2021
- Field of study
We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4–7 days or ≥ 8 days of 1.25 (1.04–1.48), p = 0.015 and 1.31 (1.11–1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care. We aimed to determine the impact of pre-operative isolation on postoperative pulmonary complications after elective surgery during the global SARS-CoV-2 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre-defined sub-group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS-CoV-2 infection. Patients who isolated pre-operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS-CoV-2 incidence and high-income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05–1.36, p = 0.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre-operative testing; use of COVID-19-free pathways; or community SARS-CoV-2 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3 days, with an OR (95%CI) at 4–7 days or ≥ 8 days of 1.25 (1.04–1.48), p = 0.015 and 1.31 (1.11–1.55), p = 0.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care
Risk of COVID-19 after natural infection or vaccinationResearch in context
- Author
- A. Lina Rosengren
- Abram Burgher
- Adam B. Brosz
- Adam Rosen
- Adam Schwartz
- Adriana Sordo Duran
- Adrienna Marquez
- Adrienne E. Shapiro
- Aeiress Duhart
- Afsoon Roberts
- Albert Liu
- Alejandro Hoberman
- Alejandro Quintín Barrat Hernández
- Alex Greninger
- Alexander Clark
- Alfredo Gilberto Guerreros Benavides
- Alice McGarry
- Alicia Arrazcaeta
- Alisha Lutat
- Alison Bondell
- Alison Pellecchia
- Allie Oplinger
- Allison Green
- Allison O'Brien
- Alpa Patel
- Alyssa-Kay Peay
- Amanda Horn
- Amanda Lilienthal
- Amanda Occhino
- Amanda Philyaw
- Amaran Moodley
- Amber Grant
- Amber Stanford
- Amesika Nyaku
- Amie Shannon
- Amina Z. Haggag
- Amit Paliwal
- Amy Caldwell
- Amy Chamberlain
- Amy Dye
- Amy Falk
- Amy Kelley
- Amy Medina
- Amy Potts
- Amy Salzl
- Amy Sherman
- Amy Starr
- Amy Thompson
- Andrea Berry
- Andrea Clement
- Andrea Wendrow
- Andrea Zimmer
- Andres Bran
- Andres Camacho-Gonzalez
- Andrew Lauria
- Andrew McConnell
- Andrew McWilliams
- Anelgine C. Yoon
- Angela Lee
- Angela R. Branche
- Angelica Kottkamp
- Angella Webb
- Ann M. Milliken
- Ann R. Falsey
- Anna S. Lok
- Anna Wald
- Anne Marit de Groot
- Anne-Marie Rick
- Annette R. Bennett
- Annie Ciambruschini
- Annie Luetkemeyer
- Anthony Kim
- Anum Abbas
- Anyela Lara
- April Pixler
- Ariana C. Stanton
- Arthur L. Zemanek
- Asha Inniss
- Ashley Kennedy
- Ashley Perez
- Ashley Warden
- Asif Noor
- Atoya Adams
- Aurelio Cruz-Valdez
- Austin Chan
- Austin Swanson
- Ayanna Walters
- Ayoade Avworo
- Bailey Jordan
- Barbara Corral
- Barbara Rizzardi
- Barbara Rizzardi
- Barbara S. Taylor
- Barry S. Zingman
- Barton G. Williams
- Beatriz Grinsztejn
- Becky Martinez
- Ben Ladner
- Benjamin Eckhardt
- Benjamin J. Luft
- Bernard Grunstra
- Beth Safirstein
- Bethanie Wilkinson
- Beverly E. Sha
- Beverly Ewing
- Bindu Balani
- Blanca Gomez
- Bo Shopsin
- Boerries Brandenburg
- Brandie Taylor
- Brandon J. Essink
- Brandy Ball
- Breanz Watkins
- Brenda Dorcely
- Brendan Levy
- Brett Gray
- Brett Leav
- Brian D.W. Chow
- Brit Sovic
- Brittany Feijoo
- Brittany Stewart
- Bruce C. Gebhardt
- Bruce G. Rankin
- Bruce McClenathan
- Bruno Valenti
- Bryan Gordon
- C. Mary Healy
- Caitlin J. Guiney
- Caitlin Moran
- Candace Smith
- Candice Montros
- Carina A. Rodriguez
- Carl Fichtenbaum
- Carl P. Griffin
- Carlos A. Fierro
- Carlos del Rio
- Carlos Lopez
- Carlos Malvestutto
- Carmel B. Dyer
- Carmen A. Paez
- Carmen Amador
- Carmen D. Zorrilla
- Carmen Medina
- Carol Ann Linebarger
- Carol Kauffman
- Carol L. Mitchell
- Carolene Stephenson
- Caroline Greene
- Carolyn Scatamacchia
- Carolyn Tran
- Carrie Johnston
- Carrie Sopher
- Catherine A. Bunce
- Catherine Mary Healy
- Catherine Q. Gular
- Cathy Laflan
- Cecilia McKeown-Bragas
- Celia Gonzalez
- Celia Maxwell
- Charles Harper
- Charles M. Fogarty
- Charlotte-Paige Rolle
- Charnell Cromer
- Chelsea Miles
- Chelsie Nutsch
- Chelsie Nutsch
- Chen S. Tan
- Chenchen Yu
- Cheryl Nuss
- Cheryl Young
- Chimeremma Nnadi
- Chinar Desai
- Christian Tomaszewski
- Christina A. Rostad
- Christina Bacher
- Christina Kennelly
- Christine Akamine
- Christine B. Turley
- Christine Hull
- Christine Wilson
- Christopher Carpenter
- Christopher Dedon
- Christopher Galloway
- Christopher Matich
- Christy Schmeck
- Christy Sweet
- Clarence B. Creech II
- Clarisse Baudelaire
- Claudia De La Matta Rodriguez
- Claudia Espinosa
- Claudio Nuñez Lagos
- Clint C. Guillory
- Clint Wilson
- Codi M. Anthony
- Colleen F. Kelley
- Colleen Jacobsen
- Connie Moya
- Cora Sonnier
- Corey G. Anderson
- Corey M. Chen
- Cornell Calinescu
- Corrina Pavetto
- Cortney Burch
- Cory J. Huffine
- Craig Dietz
- Cristina Cicogna
- Crystal Rowell
- Cynthia Becher Strout
- Cynthia Brown
- Cynthia Bueno
- Cynthia L. Gay
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- Cynthia Montano-Pereira
- Cyrus Hoseyni
- Dakotah C. Lane
- Dalia Tovar
- Daniel Duncanson
- Daniel Hoft
- Daniel Kaul
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- Daniel T. Lawler
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- Danielle Raley
- Danny Sugimoto
- Danyel Johnson
- Darlene Bartilucci
- David B. Musante
- David Beckmann
- David Browder
- David Dellaero
- David Fitz-Patrick
- David Halpert
- David I. Bernstein
- David J. Diemert
- David J. Ensz
- David Kline
- David L. Fried
- David Metzger
- David Pampe
- David Pitrak
- David R. Andes
- David Rosenberg
- David Tatelbaum
- David Wohl
- Dawn Furey
- Dawn Robison
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- Dean M. Boswell
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- Diana Badillo
- Diana F. Florescu
- Diana Vegas
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- Dima Dandachi
- Dirk Heerwegh
- Dolores Rijos
- Donald M. Brandon
- Donald Quinn
- Donna Percy
- Doris Franco-Vitteri
- Douglas S. Denham
- E. Javier Pretell Alva
- Edgar Garcia
- Edith Swann
- Eduardo Gabriel Vázquez Saldaña
- Edward C. Jones-López
- Edward E. Walsh
- Edward Ellerbeck
- Edward M. Tavel Jr.
- Elham Ghadishah
- Elie Gharib
- Elisa Swieboda
- Elissa Malkin
- Elizabeth Barranco-Santana
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- Elizabeth Bruce
- Elizabeth Danford
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- Elizabeth Parker
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- Ellie Carmody
- Elliot DeHaan
- Elwaleed Elnagar
- Emily Degan
- Emily Oppenheim
- Emma Bainbridge
- Emmanuel B. Walter
- Eneyda Giuvanela Llerena Zegarra
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- Ernesto Delgado
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- Fan Yang
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- Fernando L. Merino
- Filip Dubovsky
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- Frank James
- Frank S. Eder
- Frank Struyf
- Fred E. Newton
- Frederick Raiser III
- Fredric Santiago
- Gail Broder
- Gary Albert
- Gary Headden
- Gary Horwith
- Gary Luckasen
- Gary Simon
- Gayle D. Hennekes
- Genevieve Beninati
- Genevieve Iwuala
- George H. Bauer Jr.
- George H. Freeman
- Georgette Ebuh
- Georgettea Geuss
- Gerald Kelty
- Germán Áñez
- Getahun Abate
- Gina Rivero
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- Glenn Wortman
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- Grant Geiger
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- Gregg H. Lucksinger
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- Gregory M. Gottschlich
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- Hanh Chu
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- Howard Schwartz
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- Hyman Scott
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- Ian Frank
- Ian Hirsch
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- Insiya Valika
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- Irene McKnight
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- Isabel Pereira
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- Jacob Coleman
- Jacqueline Miller
- Jacqueline Muenzner
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- Jaleh Ostovar
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- Jason Milligan
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- Jayasree Krishnankutty
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- Jeb Andrews
- Jeff Kingsley
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- Raphael J. Landovitz
- Raymond Cornelison
- Rebecca Boas
- Rebecca J. Kurnat
- Rebecca P. Madan
- Rebecca Pitotti
- Rebecca Zash
- Rebone M. Maboa
- Renea Henderson
- Reuben Martinez
- Reza Parungao
- Rhodna Fouts
- Rica Santiago
- Richard Calderone
- Richard Gorman
- Richard L. Gibson
- Richard M. Glover II
- Richard M. Novak
- Richard Powell
- Richard Rupp
- Richard Starlin
- Rickey D. Manning
- Riemke Brakema
- Ripley R. Hollister
- Robert Brownlee
- Robert J. Buynak
- Robert J. Ulrich
- Robert Jeanfreau
- Robert L. Atmar
- Robert M. Grossberg
- Robert Riesenberg
- Robert S. Call
- Robert Samuels
- Robert Schmidt
- Robert Striker
- Robert W. Coombs
- Robert W. Frenck Jr.
- Roberto A. Viau Colindres
- Roberto C. Arduino
- Robin Hilder
- Robin Mason
- Robyn Hartvickson
- Rodney E. Sturgeon
- Roger J. Bedimo
- Rola G. Rucker
- Ronald Ackerman
- Ronald Lubelchek
- Roni Gray
- Rosa MacBryde
- Rosa Negron
- Rosamond Hong
- Rosario Sanchez
- Rozeli Shelly
- Rusty Greene
- Ruth Paiano
- Ruth S. Pinilla
- Ryan C. Maves
- Ryan Israelsen
- Ryan Little
- Ryan P. Starr
- Ryan Tomlinson
- S. Hasan Naqvi
- Saadia Khizer
- Sabina Raja
- Sade Tukuru
- Sally Eppenbach
- Samantha Williams
- Samira Shairi
- Sandra Erickson
- Sandra Janeth Ortega Domínguez
- Sandra Kelman
- Sandra Shelton
- Sarah Afework
- Sarah Dzigiel
- Sarah E. Rutstein
- Sarah Galloway
- Sarah Gordon
- Sarah M. Ingalsbe-Geno
- Sarah Omodele
- Satoshi Kamidani
- Sauda Muhammad
- Scott Borgetti
- Scott Kahney
- Scott N. Syndergaard
- Sebastian Garcia Escallon
- Secia Díaz-Miralrio
- Sergio E. Recuenco
- Sha-Wanda Richmond
- Shamika Huskey
- Shana Harshell
- Shanda Gower
- Shane G. Christensen
- Shannen Seversen
- Shannon Rodman
- Shannon Walker
- Sharine Phan
- Sharita Tedder-Edwards
- Sharon A. Riddler
- Sharon E. Frey
- Sharon Kohrs
- Sharon Nachman
- Sharzhaad Molina Guizar
- Shashi Kapadia
- Shauna H. Gunaratne
- Sheetal Kandiah
- Shelby Olds
- Shelby Pickle
- Sherif Naguib
- Sherrie Baker
- Sherry Lamberth
- Sheryl L. Henderson
- Shireen H. Jaffer
- Shishir K. Khetan
- Shivanjali Shankaran
- Shobha Swaminathan
- Sigridh Muñoz-Gómez
- Siham Mahgoub
- Sikhongi Phungwayo
- Silvano Omar Martínez Pérez
- Simbarashe G. Takuva
- Simmy Pinto
- Sinikka L. Green
- Sonal Munsiff
- Sonia Guerrero
- Sonja Neumeister
- Spyros A. Kalams
- Srilatha Edupuganti
- Stacy Ford
- Stacy Slechta
- Stanford Plavin
- Stefanie Mott
- Stefanie Tyson
- Stephan C. Sharp
- Stephan Hong
- Stephanie Andree
- Stephanie Rolsma
- Stephanie Skipper
- Stephanie Sterling
- Stephen A. Spector
- Stephen Daniels
- Stephen Morris
- Stephen R. Walsh
- Stephen R. Walsh
- Steve Clemons
- Steven E. Carsons
- Steven Palmer
- Steven Shinn
- Steven Shoptaw
- Steven Sperber
- Stuart H. Cohen
- Surisday Mederos
- Susan Jeanfreau
- Susan Kline
- Susan L. Koletar
- Susan Parker
- Susanne Doblecki-Lewis
- Suzanna Studdard
- Suzanne Fiorillo
- Suzanne Gharib
- Suzanne Swan
- Sybil G. Hosek
- Szheckera Fearon
- Tamara Richards
- Tambra Dora
- Tameika Scott
- Tami Wahlin
- Tammi L. Shlotzhauer
- Tana Bourgeois
- Tanya Hutchins
- Taryn Petty
- Tatiana Beresnev
- Tavane Harrison
- Taylor Nelson
- Teletha Gipson
- Teresa A. Batteiger
- Teresa Becker
- Teresa Deese
- Teresa S. Sligh
- Teri Thompson-Seim
- Terri Moye
- Terry D. Klein
- Terry L. Poling
- Terry Piedra
- Theresa Hegmann
- Thomas B. Campbell
- Thomas C. Klein
- Thomas C.S. Martin
- Thomas Mellman
- Thomas Patterson
- Thomas Weiss
- Tiffany Esinhart
- Tiffany Nemecek
- Tiffany Schwasinger-Schmidt
- Tilly Varughese
- Timothy J. Hatlen
- Timothy P. Vachris
- Timothy Shope
- Timothy W. Schacker
- Timothy Wilkin
- Tina Tong
- Tina Wang
- Toby Briskin
- Todd Simmons
- Tom Fiel
- Toni Robinson
- Toni White
- Tracy Okonya
- Tracy R. Klein
- Trina L. Reynolds
- Troy Holdeman
- Tyler D. Bold
- Uriel R. Felsen
- Valentine M. Ebuh
- Valeria D. Cantos
- Valerie K. Arnold
- Vanessa Abad
- Vanessa Raabe
- Veronica G. Fragoso
- Veronica Garcia-Fragoso
- Veronica Procasky
- Veronica Viar
- Vicki E. Miller
- Vickie Leathers
- Victoria Andriulis
- Victoria Engler
- Victoria Mosteller
- Victoria R. Anderson
- Vida Veronica Ruiz Herrera
- Vincent Huynh
- Vincent Mirkil
- Vivek Rajasekhar
- Viviana Gonzalez
- Vladimir Berthaud
- Walter Patton
- Wanda Ramon
- Waseem Chughtai
- Wayne L. Harper
- Wayne Woo
- Wendell Lewis
- Wendell Lewis III
- Wendy A. Keitel
- Wesley Campbell
- Wesley Van Ever
- Westly Keating
- Whitney West
- Will Hernandez
- William B. Davis
- William B. Smith
- William H. Jones
- William Jennings
- William Kirby
- William P. Silver
- William R. Hartman
- William S. Davis Jr.
- William Schnitz
- William Seger
- Winniberg Stephany Alvarez León
- Winston Cavert
- Xiaomi Tong
- Yaa D. Oppong
- Yi H. Wu
- Ying Huang
- Yogesh K. Paliwal
- Youyi Fong
- Yunda Huang
- Yunda Huang
- Yvonne Davis
- Zachary Bittner
- Zainab Rizvi
- Zindy Yazmín Zárate Hinojosa
- Zudi-Mwak Takizala
- Publication venue
- Elsevier
- Publication date
- 01/10/2023
- Field of study
Summary: Background: While vaccines have established utility against COVID-19, phase 3 efficacy studies have generally not comprehensively evaluated protection provided by previous infection or hybrid immunity (previous infection plus vaccination). Individual patient data from US government-supported harmonized vaccine trials provide an unprecedented sample population to address this issue. We characterized the protective efficacy of previous SARS-CoV-2 infection and hybrid immunity against COVID-19 early in the pandemic over three-to six-month follow-up and compared with vaccine-associated protection. Methods: In this post-hoc cross-protocol analysis of the Moderna, AstraZeneca, Janssen, and Novavax COVID-19 vaccine clinical trials, we allocated participants into four groups based on previous-infection status at enrolment and treatment: no previous infection/placebo; previous infection/placebo; no previous infection/vaccine; and previous infection/vaccine. The main outcome was RT-PCR-confirmed COVID-19 >7–15 days (per original protocols) after final study injection. We calculated crude and adjusted efficacy measures. Findings: Previous infection/placebo participants had a 92% decreased risk of future COVID-19 compared to no previous infection/placebo participants (overall hazard ratio [HR] ratio: 0.08; 95% CI: 0.05–0.13). Among single-dose Janssen participants, hybrid immunity conferred greater protection than vaccine alone (HR: 0.03; 95% CI: 0.01–0.10). Too few infections were observed to draw statistical inferences comparing hybrid immunity to vaccine alone for other trials. Vaccination, previous infection, and hybrid immunity all provided near-complete protection against severe disease. Interpretation: Previous infection, any hybrid immunity, and two-dose vaccination all provided substantial protection against symptomatic and severe COVID-19 through the early Delta period. Thus, as a surrogate for natural infection, vaccination remains the safest approach to protection. Funding: National Institutes of Health