A real-space, rela-time method for the dielectric function

We present an algorithm to calculate the linear response of periodic systems in the time-dependent density functional thoery, using a real-space representation of the electron wave functions and calculating the dynamics in real time. The real-space formulation increases the efficiency for calculating the interaction, and the real-time treatment decreases storage requirements and the allows the entire frequency-dependent response to be calculated at once. We give as examples the dielectric functions of a simple metal, lithium, and an elemental insulator, diamond.Comment: 17 pages, Latex, 5 figure

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Agua de coco, suero fetal bovino, aloe vera y sus combinaciones para criopreservar semen ovino

Se evaluó agua de coco (AC), (Cocus nucifera) y su combinación con suero fetal bovino (SFB) o aloe vera (AV), (Aloe barbadensis) para preservar semen ovino. El diluyente base fue 50 p.100 AC y 50 p.100 citrato de sodio (2,9 p.100), con 10, 20, 30, 40, 50, 60 y 70 p.100 de SFB o AV. Se utilizó un ovino Blackbelly. Con un modelo de regresión múltiple con intercepto cero, se evaluaron motilidad progresiva (MP) y espermas vivos (EV), en cinco etapas: al diluir el semen a 35ºC, finalizado el equilibramiento, concluida la congelación, y a las 48 h y 90 d poscongelamiento. La mayoría de las combinaciones tuvieron valores iguales o superiores al testigo con 40 p.100 de MP a 90 d poscongelamiento aunque las combinaciones 10-70 SFB y 40-40 AV fueron mejores con 60 p.100 de MP. En conclusión las diferentes combinaciones de AC con SFB o AV, fueron apropiadas para la preservación de semen ovino, salvo las combinaciones en donde se excedía el 50 p.100 de AV

Agua de coco, suero fetal bovino, aloe vera y sus combinaciones para criopreservar semen ovino

Se evaluó agua de coco (AC), (Cocus nucifera) y su combinación con suero fetal bovino (SFB) o aloe vera (AV), (Aloe barbadensis) para preservar semen ovino. El diluyente base fue 50 p.100 AC y 50 p.100 citrato de sodio (2,9 p.100), con 10, 20, 30, 40, 50, 60 y 70 p.100 de SFB o AV. Se utilizó un ovino Blackbelly. Con un modelo de regresión múltiple con intercepto cero, se evaluaron motilidad progresiva (MP) y espermas vivos (EV), en cinco etapas: al diluir el semen a 35ºC, finalizado el equilibramiento, concluida la congelación, y a las 48 h y 90 d poscongelamiento. La mayoría de las combinaciones tuvieron valores iguales o superiores al testigo con 40 p.100 de MP a 90 d poscongelamiento aunque las combinaciones 10-70 SFB y 40-40 AV fueron mejores con 60 p.100 de MP. En conclusión las diferentes combinaciones de AC con SFB o AV, fueron apropiadas para la preservación de semen ovino, salvo las combinaciones en donde se excedía el 50 p.100 de AV