Subaru Studies of the Cosmic Dawn

An overview on the current status of the census of the early universe population is given. Observational surveys of high redshift objects provide direct opportunities to study the early epoch of the Universe. The target population included are Lyman Alpha Emitters (LAE), Lyman Break Galaxies (LBG), gravitationally lensed galaxies, quasars and gamma-ray bursts (GRB). The basic properties of these objects and the methods used to study them are reviewed. The present paper highlights the fact that the Subaru Telescope group made significant contributions in this field of science to elucidate the epoch of the cosmic dawn and to improve the understanding of how and when infant galaxies evolve into mature ones.Comment: 14 pages, 11 figures, accepted for publication in the Proceedings of the Japan Academy, Series

Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Interactions between bicrystal Josephson junctions in a multilayer structure

We have fabricate and studied a variety of devices based on stacked YBa2Cu3Ox bicrystal Josephson junctions in a multilayer structure. The proximity of the junctions in the two layers produces a large number of effects based on interactions between the junctions. Voltage locking and current locking were observed in the stacked junctions. The voltage locking is due to the ac path provided by a SrTiO3 layer between the stacked junctions. The current locking is likely the result of a Josephson vortex interaction

A novel multilayer circuit process using YBa2Cu3Ox /SrTiO3 thin films

A process combining hydrofluoric acid (HF) and Ar+ ion milling has been used to make YBa2Cu3Oχ/SrTiO3/YBa2Cu2Oχ (YBCO/STO/YBCO) multilayer test circuits. Low-angle steps can be readily etched in STO and YBCO films with this process. YBCO lines crossing 5° steps have about the same critical temperature Tc (89–90 K) and critical current density Jc (\u3e1X106 A/cm2 at 86 K) as lines on planar surfaces. Via connections have the same Tc as other circuit components and adequate critical currents for most circuit designs

An improved multi-layer fabrication process for YBa\u3csub\u3e2\u3c/sub\u3eCu\u3csub\u3e3\u3c/sub\u3eO\u3csub\u3e7-x\u3c/sub\u3e-based circuits

Improved via connections in structures of YBa2Cu3O7-x/SrTiO3/ YBa2Cu3O7-x (YBCO/STO/YBCO) multilayers have been made using a combined HF wet-etching and ion-milling process. The critical current density Jc of the via is as high as 2×106 A/cm2 at 76 K, and is dominated by edge contacts in the ab-plane, YBCO and Sr2AlNbO6 (SAN) multilayer test circuits were also made with this process. The 4° crossovers in a SAN test chip had a critical temperature Tc of 88 K and Jc of 1.5×106 A/cm2 at 81 K, very close to those of the planar film, showing no evidence of weak links in the YBCO crossing low angle SAN steps