1,615 research outputs found
Developing power in word recognition
Thesis (M.A.)--Boston University, 1945. This item was digitized by the Internet Archive
Central Acceptance Testing for Camera Technologies for CTA
The Cherenkov Telescope Array (CTA) is an international initiative to build
the next generation ground based very-high energy gamma-ray observatory. It
will consist of telescopes of three different sizes, employing several
different technologies for the cameras that detect the Cherenkov light from the
observed air showers. In order to ensure the compliance of each camera
technology with CTA requirements, CTA will perform central acceptance testing
of each camera technology. To assist with this, the Camera Test Facilities
(CTF) work package is developing a detailed test program covering the most
important performance, stability, and durability requirements, including
setting up the necessary equipment. Performance testing will include a wide
range of tests like signal amplitude, time resolution, dead-time determination,
trigger efficiency, performance testing under temperature and humidity
variations and several others. These tests can be performed on fully-integrated
cameras using a portable setup at the camera construction sites. In addition,
two different setups for performance tests on camera sub-units are being built,
which can provide early feedback for camera development. Stability and
durability tests will include the long-term functionality of movable parts,
water tightness of the camera housing, temperature and humidity cycling,
resistance to vibrations during transport or due to possible earthquakes,
UV-resistance of materials and several others. Some durability tests will need
to be contracted out because they will need dedicated equipment not currently
available within CTA. The planned test procedures and the current status of the
test facilities will be presented.Comment: 8 pages, 3 figures. In Proceedings of the 34th International Cosmic
Ray Conference (ICRC2015), The Hague, The Netherlands. All CTA contributions
at arXiv:1508.0589
Beings in their own right? Exploring Children and young people's sibling and twin relationships in the Minority World
This paper examines the contributions that the sociological study of sibship and twinship in the Minority World can make to childhood studies. It argues that, in providing one forum within which to explore children and young people's social relationships, we can add to our understanding of children and young people's interdependence and develop a more nuanced understanding of agency. As emergent subjects, children, young people and adults are in a process of ‘becoming’. However, this does not mean that they can ‘become’ anything they choose to. The notion of negotiated interdependence (Punch 2002) is useful in helping us to grasp the contingent nature of children and young people's agency
Optimizing projectional radiographic imaging of the abdomen of obese patients: an e-Delphi study
This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Purpose: Obesity is increasing in prevalence globally, with increased demands placed on radiology departments to image obese patients to assist with diagnosis and management. The aim of this study was to determine perceived best practice techniques currently used in clinical practice for projectional radiography of the abdomen for obese patients with the aim to help elucidate areas for future research and education needs in this field. Experimental Design: A two round e-Delphi study was undertaken to establish a consensus within a reference group of expert Australian clinical educator diagnostic radiographers (CEDRs). Initially, a conceptual map of issues regarding imaging obese patients was undertaken by analysing interview transcripts of 12 CEDRs. This informed an online questionnaire design used in Delphi rounds 1 and 2. A consensus threshold was set <75% “agreement/disagreement”, with 15 and 14 CEDRs participating in rounds 1 and 2, respectively. Results: Seven of the 11 statements reach consensus after round 2. Consensus on using a combination of higher peak kilovoltage (kVp) and milliampere-seconds (mAs) to increase radiation exposure increased source-to-image distance and tighter collimation was achieved. There was no consensus regarding patient positioning practices or patient communication strategies. The expert group reported the importance of personal confidence and treating patients as individuals when applying techniques. Conclusion: Diversity of experts' opinions and current practice may be due to the variations in obese patients’ size and presentation. Therefore, there is a need for extensive empirical evidence to underpin practice and education resources for radiographers when imaging obese patients
Building a Sustainable Comprehensive Women's Health Program: The Michigan Model
The Women's Health Program at the University of Michigan was established in 1993 and has developed into a successful, federally supported program that links clinical research and education activities across the University. It has focused on human resource capacity building, sustainable financial support and infrastructure, and adaptability to change and opportunities. Widely accepted standards, demonstrated value, committed leaders/champions, and participatory culture have contributed to its success and are important to its future.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/63102/1/jwh.2006.0192.pd
IMECE2006-14283 AN EXPERIMENTAL INVESTIGATION OF FLOW FIELDS WITHIN MINIATURE SCALE CENTRIFUGAL PUMPS
ABSTRACT Thermal management has become a key point in the development of contemporary electronics systems. It is evident that heat fluxes are currently approaching the limits of conventional forced air cooling, and that liquid technologies are now under consideration. The objective of this paper is to investigate the flow fields within a miniature scale centrifugal pump in order to determine velocity profiles describing the flow. The experimental setup consisted of a hydrodynamic test bed constructed to measure the pressure-flow characteristic of a centrifugal pump with a rated volumetric flow of 9 l/min. The impeller diameter of the pump under consideration was 34.3mm, and the characterisation experiments were carried out at a constant impeller speed. Particle-Image Velocimetry (PIV) was used to measure velocity profiles within the volute section of the pump. Synchronised velocity profiles are illustrated for three operating points on the pump characteristic curve. A hydrodynamic analysis of the velocity vectors at the impeller tip is also included, and pump model verification is then discussed based on the comparison between the theoretical predictions and the PIV data
Potassium is a trigger for conformational change in the fusion spike of an enveloped RNA virus
Many enveloped viruses enter cells through the endocytic network, from which they must subsequently escape through fusion of viral and endosomal membranes. This membrane fusion is mediated by virus-encoded spikes that respond to the dynamic endosomal environment, which triggers conformational changes in the spikes that initiate the fusion process. Several fusion triggers have been identified and include pH, membrane composition, and endosome-resident proteins, and these cues dictate when and where viral fusion occurs. We recently reported that infection with an enveloped bunyavirus requires elevated potassium ion concentrations [K⁺], controlled by cellular K⁺ channels, that are encountered during viral transit through maturing endosomes. Here we reveal the molecular basis for the K⁺ requirement of bunyaviruses through the first direct visualization of a member of the Nairoviridae family, namely Hazara virus (HAZV), using cryo-EM. Using cryo-electron tomography, we observed HAZV spike glycoproteins within infectious HAZV particles exposed to both high and low [K⁺], which showed that exposure to K⁺ alone results in dramatic changes to the ultrastructural architecture of the virion surface. In low [K⁺], the spikes adopted a compact conformation arranged in locally ordered arrays, whereas, following exposure to high [K⁺], the spikes became extended, and spike–membrane interactions were observed. Viruses exposed to high [K⁺] also displayed enhanced infectivity, thus identifying K⁺ as a newly defined trigger that helps promote viral infection. Finally, we confirmed that K⁺ channel blockers are inhibitory to HAZV infection, highlighting the potential of K⁺ channels as anti-bunyavirus targets
Generationing development
The articles in this special issue present a persuasive case for accounts of development to recognise the integral and fundamental roles played by age and generation. While the past two decades have witnessed a burgeoning of literature demonstrating that children and youth are impacted by development, and that they can and do participate in development, the literature has tended to portray young people as a special group whose perspectives should not be forgotten. By contrast, the articles collected here make the case that age and generation, as relational constructs, cannot be ignored. Appropriating the term ‘generationing’, the editors argue that a variety of types of age relations profoundly structure the ways in which societies are transformed through development – both immanent processes of neoliberal modernisation and the interventions of development agencies that both respond and contribute to these. Drawing on the seven empirical articles, I attempt to draw some of the ideas together into a narrative that further argues the case for ‘generationing’ but also identifies gaps, questions and implications for further research
The changing pattern of domestic cannabis cultivation in the UK and its impact on the cannabis market
With improvements in both technology and information cannabis is being increasingly grown indoors for domestic use, rather than being imported. This study examines 50 cannabis farms detected by an English police force, and examines the characteristics of the 61 suspects associated with them. The study highlights a UK pattern in domestic cultivation, that is moving away from large scale commercial cultivation, at times co-ordinated by South East Asian organised crime groups, to increased cultivation within residential premises by British citizens. Offenders range from those who have no prior criminal history to those who are serious and persistent offenders. The ramifications for law enforcement agencies and policy formers are discussed
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