3,154 research outputs found
Experimental Study of the Superconducting Microstrip Antenna as a Protective Device of the Receiver From Electromagnetic Damage
The paper presents the results of experimental studies of a superconducting protective antenna, which consists of a high-temperature film deposited by a magnetron or a laser beam on a substrate. The work is carried out:- analysis of the selection criteria for the substrate type (Al2O3, Y2O3, SrTiO3, MgO) and the method for depositing a high-temperature superconducting film (HTSF) on its surface – YBaCuO- analysis of the methods of making contacts, which allow to reduce losses when passing a signal from the superconducting microstrip antenna to the waveguide path.The aim of this article is determination of the parameters of a prototype sample of a microstrip antenna device made from HTSF: transient characteristics of high-temperature superconductors, HTSF impulsive characteristics, recovery time of the superconducting state after the action of a powerful pulse on the protective device, the amplitude-frequency characteristics of the protective device in the superconducting state. This will allow to evaluate the possibility of using a microstrip antenna device made from high-temperature superconductors to protect the receiving systems from electromagnetic damage. The absence of a unified theory of high-temperature superconductivity leads to the need to select an analytical form of the functions of the amplitude-frequency characteristics of superconducting protection, and for this mathematical models are used in the programs "APPROX", "MathCAD14.0". The reliability of the obtained results of mathematical modeling of the processes of protection and recovery of the superconducting state after electromagnetic shock are confirmed in the course of experimental studies (an error of 0.15%)
Method to extrapolate the stress-rupture curves of high-temperature materials
Наведено метод прогнозування тривалої міцності матеріалів, виходячи з концепції базових діаграм. Запропоновано прості співвідношення, що зв’язують розрахункову довговічність і відповідне їй діюче напруження, визначене по базовій діаграмі. Ефективність методу проілюстровано при розрахунках довговічності сталей SUS 316-HP (18Cr-12Ni-Mo) і JIS SCMV 4NT (2,25Cr-1Mo) для досить широких діапазонів діючих напружень і температур. Показано перевагу даного підходу відповідно найпоширеніших параметричних методів Ларсона-Міллера, Орра-Шербі-Дорна, Менсона-Саккопа, Труніна й ін.The method to predict the stress-rupture strength of materials using 3000–7000 h test data and the master-curve concept is presented. Simple formulas relating the theoretical lifetime and the corresponding stress determined from the master curve are proposed. To determine accurately the difference between the true stress and the stress found from the master curve, an approximating function of β based on available test data is used. The quantity β is the cotangent of the angle between the ordinate axis and a segment of the stress-rupture curve plotted on log–log scale.
The parameters of the approximating function can be assumed to be either invariant to the test temperature or determined from the difference between the experimental and calculated values for each isotherm. The assumption of invariance is equivalent to the hypothesis that the family of stress-rupture curves can be reduced to a unified curve. The latter approach results in a better agreement between calculated and experimental data. In some cases, however, the assumption that the parameters of the approximating function are constant allows obtaining reliable results with accuracy sufficient for practical purposes.
The method is capable of extrapolating the lifetime to values that are more than in 30 times greater than the available experimental data. The efficiency of the method is illustrated by calculating the lifetime of steels SUS316-HP (18Cr–12Ni–Mo) and JIS SCMV 4NT (2.25Cr–1Mo) for quite wide ranges of stress and temperature. The linear dependence of the mismatch function on β is used as the approximating function. Using a function rather than a set of constant parameters, as in the master curve method, always results in a better agreement between calculated and experimental data when extrapolating stress-rupture curves. It is shown that the method has advantages over the master-curve approach and popular parameters such as Larson-Miller, Orr-Sherby-Dorn, Manson-Succop, Conrad’s, Korchynsky-Clauss, and Trunin’s. The parameters of the linear models are calculated using multifactor linear regression
Modelling of the creep processes and the stress-rupture strength of materials
Запропоновано модель для опису одновимірних неізотермічних процесів деформування, що враховує пошкодженість при повзучості для широких діапазонів напруження і температури. Уточнено області застосування параметричних методів для прогнозування тривалої міцності матеріалів. Подано методику для конкретизації запропонованих рівнянь стану та показано їх ефективність при описуванні повзучості матеріалів.A model for describing one-dimensional nonisothermal deformation processes that considers the damage under creep for a wide range of stress and temperature is proposed. The influence of the stress state and temperature on the creep rate variation is taken into account by means of a scalar function of damage level, with all three specific portions of the creep curve being described. The Lemaitre and Plumtree model is used as an evolutionary relationship, considering that its parameters are stress- and temperature-dependent. Based on the relationships described by the stress-rupture curves, the procedure is proposed for specifying the parameters of the evolutionary equation.
The application areas of the known parametric methods for predicting the stress-rupture strength of materials are specified based on the experimental investigations. It is shown that these methods allow extrapolating the creep-rupture life to the values that exceed the available experimental data by no more than a factor of 10 with accuracy sufficient for engineering purposes.
To extend the prediction capabilities to 300 thousand hours or more on the basis of the test results of limited duration, a modified base diagram method is proposed. A linear dependence is proposed to approximate the residual function in terms of the base diagram method. In the case, where it is impossible to reduce the stress-rupture curves to a common curve, the residual function parameters are determined from the experimental data for one isotherm. In this case, its parameters are the functions of temperature. The advantages of this approach over the Larson–Miller, Orr–Sherby–Dorn, Manson–Succop, Trunin and other parameters are shown during the extrapolation of stress-rupture strength to long lifetimes.
To describe the dependence of the creep strain rate on the stress, creep strain, damage level function and temperature, the relationship of the strain-hardening theory is used with the corresponding change of the stress value for the effective stress defined by Kachanov. The procedure is proposed for specifying the constitutive equations in terms of the strain distribution in creep and the stress-rupture curves. The obtained values of the parameters calculated at the fixed stress and temperature values are approximated using the smoothing-surface approximation. The efficiency of describing the creep processes is shown in the strain calculations for alloy 19Cr-18Co-4Mo-3Ti-3Al-B and steels 12Cr-18Ni-Mo, 21Cr-32Ni-Ti-Al. Good agreement is shown between the predicted and experimentally obtained data for quite wide ranges of working stress and temperature
Prediction of elasticity characteristics for the unidirectional polymer composite materials at high temperatures
Досліджується ефективність прогнозування характеристик пружності односпрямованих полімерних композиційних матеріалів при високих температурах. Деформування таких матеріалів при підвищенні температури описується за допомогою лінійної моделі механіки багатофазних середовищ. Механічні властивості абліруючих матеріалів залежить від температури і швидкості нагріву. Показано, що питома щільність неармованої матриці, пучка вуглецевих волокон і полімерних односпрямованих вуглепластиків істотно змінюється при підвищенні температури. Наводиться порівняння розрахункових характеристик пружності абліруючих трансверсально ізотропних матеріалів з експериментальними результатами.The efficiency of elasticity characteristics prediction for the unidirectional polymer composite materials at high temperatures is investigated. The deformation of such materials at the elevated temperature is described using the linear model of mechanics of multiphase media. The mechanical properties of the ablating materials depend on the temperature and the heating rate. It is shown that the specific density of the unreinforced matrix, the bundle of polymer fibers and the unidirectional carbon fiber-reinforced plastics changes significantly at the elevated temperature. The comparison between the calculated elasticity characteristics of the ablating transversely isotropic materials and their experimental results is given.Исследуется эффективность прогнозирования характеристик упругости однонаправленных полимерных композиционных материалов при высоких температурах. Деформирование таких материалов при повышении температуры описывается при помощи линейной модели механики многофазных сред. Механические свойства аблирующих материалов зависят от температуры и скорости нагрева. Показано, что удельная плотность неармированной матрицы, пучка углеродных волокон и полимерных однонаправленных углепластиков существенно изменяется при повышении температуры. Приводится сравнение расчетных характеристик упругости аблирующих трансверсально изотропных материалов с экспериментальными результатами
Identification of circular eco-subsystems for end-of-life aviation composite components based on a systematized R6-strategy
The demand of composites in the aviation and space industry has increased significantly in recent decades. This is due to the excellent properties of composite materials, especially their low density and design flexibility. However, the reuse and further utilization of composite structures and their materials provide new challenges for the recycling sector. In accordance with the ’Green Deal’ of the European Commission, new pathways are required to ensure an effective and economic reuse of composite components at their end-of-life (EoL). We discuss a strategic approach for returning decommissioned parts of aviation composites back into the material cycle with a particular focus on waste reduction, as well as the decrease of the associated energy demand and emissions. Therefore, a sustainable strategy to exploit various circular possibilities was applied, consisting of the six R-strategies: reuse, repair, refurbish, remanufacture, repurpose and recycling. The Multi-Tiered System of Support is transferred to the introduced R6-strategy. The concept provides an approach to address the challenges of reintroducing EoL composites into the material chain. Based on the systematized R6-strategy it was possible to identify circular eco-subsystems for aviation composite components with minimal effort. Finally, this paper discusses a potential criterion used for assigning EoL aviation composites to the various eco-subsystems
ФІНАНСОВА СТІЙКІСТЬ БАНКІВ ЯК ЗАПОРУКА СТАБІЛЬНОСТІ БАНКІВСЬКОЇ СИСТЕМИ УКРАЇНИ (Financial stability of banks as a guarantee of stability of the banking system of Ukraine)
У статті досліджено основні проблеми функціонування банківської системи України, визначено та обґрунтовано
необхідність розроблення ефективних методів підвищення фінансової стійкості банківських
установ (In this research main problems of the banking system of Ukraine are defined and the necessity of developing
methods to increase effectiveness in the financial stability of the banking institutions
Identification and Environmental Assessments for Different Scenarios of Repurposed Decommissioned Wind Turbine Blades
The rapidly growing wind industry poses a fundamental problem for wind turbine blade (WTB) disposal in many areas of
the world. WTBs are primarily manufactured from composites consisting of a thermoset matrix and reinforcing fibers. Currently,
there are no economically viable recycling technologies available for such large-scale composite products. Thus, other
treatment strategies for disposed WTBs have to be considered. This study explores the repurpose of WTBs as a promising
alternative approach from a processual and technological point of view. For this purpose, the study is guided by the categorization
into four different types of repurposed applications: high-loaded complete structure (T1), low-loaded complete
structure (T2), high-loaded segmented structure (T3), and low-loaded segmented structure (T4). A three-dimensional CAD
model of an Enercon-40/500 (E40) wind turbine blade is derived in a reverse engineering procedure to obtain knowledge
about the actual geometry of the WTB. Based on the design, three ecosystems of product scenarios (S) with different
manufacturing technologies involved are investigated: a climbing tower (S1), a playground (S2) and the combination of a
photovoltaic (PV)-floating pontoon, and a lounger (S3). A screening life cycle assessment (LCA) is conducted to evaluate
the three repurposed scenarios according to environmental aspects. It is shown that the repurpose of E40 WTB composite
material can reduce the environmental impact and leads to significant resource savings in relation to a reference product
of similar quality. A particularly high saving potential is identified for the substitution of emission-intensive materials in
construction applications. Furthermore, it is found that transport processes are the primary contributor to the environmental
impact of repurposed applications
СЕСТРИНСЬКИЙ ДОГЛЯД ЗА ХВОРИМИ З АСТЕНІЄЮ ПРИ ПАТОЛОГІЇ СИСТЕМИ КРОВІ
The article adduces the main causes of development pathophysiology peculiarities, diagnosis, treatment of the weakness syndrome and nursing care for patients with asthenia at diseases of the blood system.У статті розглянуто основні причини розвитку, особливості патофізіології, діагностика, лікування синдрому слабості та сестринський догляд за хворими з астенією при захворюваннях крові
Enoxaparin for primary thromboprophylaxis in ambulatory patients with coronavirus disease-2019 (the OVID study): a structured summary of a study protocol for a randomized controlled trial.
The OVID study will demonstrate whether prophylactic-dose enoxaparin improves survival and reduces hospitalizations in symptomatic ambulatory patients aged 50 or older diagnosed with COVID-19, a novel viral disease characterized by severe systemic, pulmonary, and vessel inflammation and coagulation activation.
The OVID study is conducted as a multicentre open-label superiority randomised controlled trial.
Inclusion Criteria 1. Signed patient informed consent after being fully informed about the study's background. 2. Patients aged 50 years or older with a positive test for SARS-CoV2 in the past 5 days and eligible for ambulatory treatment. 3. Presence of respiratory symptoms (i.e. cough, sore throat, or shortness of breath) or body temperature >37.5° C. 4. Ability of the patient to travel to the study centre by private transportation, performed either by an accompanying person from the same household or by the patient themselves 5. Ability to comply with standard hygiene requirements at the time of in-hospital visit, including a face mask and hand disinfectant. 6. Ability to walk from car to study centre or reach it by wheelchair transport with the help of an accompanying person from the same household also complying with standard hygiene requirements. 7. Ability to self-administer prefilled enoxaparin injections after instructions received at the study centre or availability of a person living with the patient to administer enoxaparin. Exclusion Criteria 1. Any acute or chronic condition posing an indication for anticoagulant treatment, e.g. atrial fibrillation, prior venous thromboembolism (VTE), acute confirmed symptomatic VTE, acute coronary syndrome. 2. Anticoagulant thromboprophylaxis deemed necessary in view of the patient's history, comorbidity or predisposing strong risk factors for thrombosis: a. Any of the following events occurring in the prior 30 days: fracture of lower limb, hospitalization for heart failure, hip/knee replacement, major trauma, spinal cord injury, stroke, b. previous VTE, c. histologically confirmed malignancy, which was diagnosed or treated (surgery, chemotherapy, radiotherapy) in the past 6 months, or recurrent, or metastatic, or inoperable. 3. Any clinically relevant bleeding (defined as bleeding requiring hospitalization, transfusion, surgical intervention, invasive procedures, occurring in a critical anatomical site, or causing disability) within 30 days prior to randomization or sign of acute bleeding. 4. Intracerebral bleeding at any time in the past or signs/symptoms consistent with acute intracranial haemorrhage. 5. Haemoglobin <8 g/dL and platelet count <50 x 10 <sup>9</sup> cells/L confirmed by recent laboratory test (<90 days). 6. Subjects with any known coagulopathy or bleeding diathesis, including known significant liver disease associated with coagulopathy. 7. Severe renal insufficiency (baseline creatinine clearance <30 mL/min calculated using the Cockcroft-Gault formula) confirmed by recent laboratory test (<90 days). 8. Contraindications to enoxaparin therapy, including prior heparin-induced thrombocytopenia and known hypersensitivity. 9. Current use of dual antiplatelet therapy. 10. Participation in other interventional studies over the past 30 days. 11. Non-compliance or inability to adhere to treatment or lack of a family environment or support system for home treatment. 12. Cognitive impairment and/or inability to understand information provided in the study information. Patient enrolment will take place at seven Swiss centres, including five university hospitals and two large cantonal hospitals.
Patients randomized to the intervention group will receive subcutaneous enoxaparin at the recommended dose of 4,000 IU anti-Xa activity (40 mg/0.4 ml) once daily for 14 days. Patients randomized to the comparator group will receive no anticoagulation.
Primary outcome: a composite of any hospitalization or all-cause death occurring within 30 days of randomization.
(i) a composite of cardiovascular events, including deep vein thrombosis (including catheter-associated), pulmonary embolism, myocardial infarction/myocarditis, arterial ischemia including mesenteric and extremities, acute splanchnic vein thrombosis, or ischemic stroke within 14 days, 30 days, and 90 days of randomization; (ii) each component of the primary efficacy outcome, within 14 days, 30 days, and 90 days of randomization; (iii) net clinical benefit (accounting for the primary efficacy outcome, composite cardiovascular events, and major bleeding), within 14 days, 30 days, and 90 days of enrolment; (iv) primary efficacy outcome, within 14 days, and 90 days of enrolment; (v) disseminated intravascular coagulation (ISTH criteria, in-hospital diagnosis) within 14 days, 30 days, and 90 days of enrolment.
Patients will undergo block stratified randomization (by age: 50-70 vs. >70 years; and by study centre) with a randomization ratio of 1:1 with block sizes varying between 4 and 8. Randomization will be performed after the signature of the informed consent for participation and the verification of the eligibility criteria using the electronic data capture software (REDCAP, Vanderbilt University, v9.1.24).
In this open-label study, no blinding procedures will be used.
The sample size calculation is based on the parameters α = 0.05 (2-sided), power: 1-β = 0.8, event rate in experimental group, pexp = 0.09 and event rate in control group, pcon = 0.15. The resulting total sample size is 920. To account for potential dropouts, the total sample size was fixed to 1000 with 500 patients in the intervention group and 500 in the control group.
Protocol version 1.0, 14 April 2020. Protocol version 3.0, 18 May 2020 Recruiting start date: June 2020. Last Patient Last Visit: March 2021.
ClinicalTrials.gov Identifier: NCT04400799 First Posted: May 26, 2020 Last Update Posted: July 16, 2020 FULL PROTOCOL: The full protocol is attached as an additional file, accessible from the Trials website (Additional file 1). In the interest in expediting dissemination of this material, the familiar formatting has been eliminated; this Letter serves as a summary of the key elements of the full protocol
Cellular actors, Toll-like receptors, and local cytokine profile in acute coronary syndromes
Aims Inflammation plays a key role in acute coronary syndromes (ACS). Toll-like receptors (TLR) on leucocytes mediate inflammation and immune responses. We characterized leucocytes and TLR expression within coronary thrombi and compared cytokine levels from the site of coronary occlusion with aortic blood (AB) in ACS patients. Methods and results In 18 ACS patients, thrombi were collected by aspiration during primary percutaneous coronary intervention. Thrombi and AB from these patients as well as AB from 10 age-matched controls without coronary artery disease were assessed by FACS analysis for cellular distribution and TLR expression. For further discrimination of ACS specificity, seven non-coronary intravascular thrombi and eight thrombi generated in vitro were analysed. In 17 additional patients, cytokine levels were determined in blood samples from the site of coronary occlusion under distal occlusion and compared with AB. In coronary thrombi from ACS, the percentage of monocytes related to the total leucocyte count was greater than in AB (47 vs. 20%, P = 0.0002). In thrombi, TLR-4 and TLR-2 were overexpressed on CD14-labelled monocytes, and TLR-2 was increased on CD66b-labelled granulocytes, in comparison with leucocytes in AB. In contrast, in vitro and non-coronary thrombi exhibited no overexpression of TLR-4. Local blood samples taken under distal occlusion revealed elevated concentrations of chemokines (IL-8, MCP-1, eotaxin, MIP-1α, and IP-10) and cytokines (IL-1ra, IL-6, IL-7, IL-12, IL-17, IFN-α, and granulocyte-macrophage colony-stimulating factor) regulating both innate and adaptive immunity (all P < 0.05). Conclusion In ACS patients, monocytes accumulate within thrombi and specifically overexpress TLR-4. Together with the local expression patterns of chemokines and cytokines, the increase of TLR-4 reflects a concerted activation of this inflammatory pathway at the site of coronary occlusion in AC
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