Research Article Status of Emotional Intelligence (EI) Level of Biomedical Science Programme in Kuala Lumpur

Abstract: Emotional Intelligence (EI) is part of those who regulate their emotions according to a logically consistent of emotional functioning. This cross-sectional study is carried out among year 1 to 3 students of Biomedical Science Programme in Kuala Lumpur The questionnaire is based on three criteria which are intrapersonal ability, stress management and general mood. The sample size is 135 students by using stratified random sampling. The general objective of this study is to determine the emotional intelligence level of Biomedical Science students among socio demographic factor. The results showed the mean of EI male students (111.84±12.92 S.D.) is lower than that in female students (112.02±10.23 S.D.), the mean of EI among student staying in campus (112.55±10.947 S.D.) are higher than cam us student staying off-campus (110.76±10.274 S.D.) and the mean of EI among first year (114.35±13.32 S.D.) is the highest compared to that in Year 2 (113.16±9.592 S.D.) and Year 3 (109.93±10.169 S.D.). However there was no significance mean difference of EI between gender, year of study and residences (p>0.05). In conclusion, Emotional Intelligence (EI) is at average level (79.7%) and it was not depending on gender year of study and residences

The effect of tobacco, XPC, ERCC2 and ERCC5 genetic variants in bladder cancer development

<p>Abstract</p> <p>Background</p> <p>In this work, we have conducted a case-control study in order to assess the effect of tobacco and three genetic polymorphisms in <it>XPC, ERCC2 and ERCC5 </it>genes (rs2228001, rs13181 and rs17655) in bladder cancer development in Tunisia. We have also tried to evaluate whether these variants affect the bladder tumor stage and grade.</p> <p>Methods</p> <p>The patients group was constituted of 193 newly diagnosed cases of bladder tumors. The controls group was constituted of non-related healthy subjects. The rs2228001, rs13181 and rs17655 polymorphisms were genotyped using a polymerase chain reaction-restriction fragment length polymorphism technique.</p> <p>Results</p> <p>Our data have reported that non smoker and light smoker patients (1-19PY) are protected against bladder cancer development. Moreover, light smokers have less risk for developing advanced tumors stage. When we investigated the effect of genetic polymorphisms in bladder cancer development we have found that ERCC2 and ERCC5 variants were not implicated in the bladder cancer occurrence. However, the mutated homozygous genotype for XPC gene was associated with 2.09-fold increased risk of developing bladder cancer compared to the control carrying the wild genotype (p = 0.03, OR = 2.09, CI 95% 1.09-3.99). Finally, we have found that the XPC, ERCC2 and ERCC5 variants don't affect the tumors stage and grade.</p> <p>Conclusion</p> <p>These results suggest that the mutated homozygous genotype for XPC gene was associated with increased risk of developing bladder. However we have found no association between rs2228001, rs13181 and rs17655 polymorphisms and tumors stage and grade.</p

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P &lt; 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Abstract Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Retrospective analysis of primary patency of vascular access maturity: a single centre experience at HTAA, Kuantan, Malaysia

Introduction Arteriovenous stula (AVF) has been proven to be the best vascular access for the purpose of haemodialyis due to its’ longevity and robustness. Unfortunately, despite of its’ popularity in Malaysia, there is a limited local data being published. HTAA is a main referral center for AVF creation for the east coast of Malaysia. We examined our data for primary patency rate and possible factors that may associates with it. Methods Patients who underwent AVF creation created by a single surgeon from July 2012 to July 2013 in Hospital Tengku Ampuan Afzan (HTAA), Kuantan were identi ed using theatre list and also logbook. Data were collected retrospectively from the patients’ medical notes. A total of 89 patients were identi ed. Primary patency rate is being assessed at 6 weeks. Statistical analysis performed using SPSS® v20. Results The patient’s median age of the patients was 53 years with a slight male predominance (53%). Majority of the subjects have no history of tobacco use (71.4%). The Malays make up the majority in ethnicity (79.6%). 53.1% and 18.4% have underlying diabetes mellitus and obesity respectively. Brachio-cephalic stulas (BCF) are the majority of AVF (71.4%) that were created. 78% of our patients had already been diagnosed with ESRF and 59% was already on dialysis upon AVF creation. 57.1% of the subjects are statins users. The mean diameters of artery and veins are 2.56mm and 2.94mm respectively. Our primary patency rate is 87.8%. Multivariate analysis shows no signi cance between the demographics and maturity but a suggestive association of venous diameter and statins with primary patency rate with p values of 0.06 and 0.07 respectively. Conclusion This study described a comparable success rate of AVF creation at our centre in to other published data. We have identi ed, venous diameter and statins use have a positive trend with primary patency rate of our AVF in a multivariate analysis

Retrospective analysis of primary patency of vascular acess maturity: A single centre experience at HTAA, Kuantan, Malaysia

Introduction Arteriovenous stula (AVF) has been proven to be the best vascular access for the purpose of haemodialyis due to its’ longevity and robustness. Unfortunately, despite of its’ popularity in Malaysia, there is a limited local data being published. HTAA is a main referral center for AVF creation for the east coast of Malaysia. We examined our data for primary patency rate and possible factors that may associates with it. Methods Patients who underwent AVF creation created by a single surgeon from July 2012 to July 2013 in Hospital Tengku Ampuan Afzan (HTAA), Kuantan were identi ed using theatre list and also logbook. Data were collected retrospectively from the patients’ medical notes. A total of 89 patients were identi ed. Primary patency rate is being assessed at 6 weeks. Statistical analysis performed using SPSS® v20. Results The patient’s median age of the patients was 53 years with a slight male predominance (53%). Majority of the subjects have no history of tobacco use (71.4%). The Malays make up the majority in ethnicity (79.6%). 53.1% and 18.4% have underlying diabetes mellitus and obesity respectively. Brachio-cephalic stulas (BCF) are the majority of AVF (71.4%) that were created. 78% of our patients had already been diagnosed with ESRF and 59% was already on dialysis upon AVF creation. 57.1% of the subjects are statins users. The mean diameters of artery and veins are 2.56mm and 2.94mm respectively. Our primary patency rate is 87.8%. Multivariate analysis shows no signi cance between the demographics and maturity but a suggestive association of venous diameter and statins with primary patency rate with p values of 0.06 and 0.07 respectively. Conclusion This study described a comparable success rate of AVF creation at our centre in to other published data. We have identi ed, venous diameter and statins use have a positive trend with primary patency rate of our AVF in a multivariate analysis

Valorization of palm oil mill sterilization condensate via synergistic green reactive extraction of bioactive compounds

Palm oil mill (POM) sterilization condensate is recognized as the source of polyphenols with interesting biological activities, for example, inflammatory processes prevention, UV protection, antioxidant, antimicrobial, and anticarcinogen. Reactive extraction is one of the promising methods for bioactive compounds (polyphenols) recovery offering various merits such as simple, efficient, easy to scale up, and high selectivity. In this work, reactive extraction of polyphenols from POM sterilization condensate using synergistic organic formulation was investigated. The extraction was performed by screening several base and synergist extractants using palm cooking oil as a green diluent. The results showed that about 85% of polyphenols were extracted using 0.25 M 1-Octanol and 0.05 M Aliquat 336 with a synergistic coefficient of 2.59. Meanwhile, the back-extraction study demonstrated that 0.3 M NaOH was selected as the most appropriate stripping agent where almost 100% of stripping performance was achieved. Therefore, the synergistic green formulation offers great potential for polyphenols recovery from POM sterilization condensate