Genealogical data of Boer and Nubian goats in Mexico

The pedigree file of the Boer and Nubian goat breeds in Mexico was constructed using the national database provided by the Asociación Mexicana de Criadores de Ganado Caprino de Registro. Field technicians routinely updated the goat national database by recording information from flocks participating in the performance-recording system. Information on animal identification number, parents, birth date, sex, breed, and farm of origin were used to undertake pedigree analyses using the ENDOG program (version 4.8). This paper presents a pedigree data file, tables and figures of characteristics of pedigree data, pedigree analyses, pedigree integrity, effective population size and genetic conservation index. The data can be used to estimate other population parameters, to monitor the genetic diversity of the Boer and Nubian goat breeds in Mexico, and also to design balanced breeding programs, maintaining genetic variation at reasonable levels and maximizing genetic progress in these populations.202

Evaluación de la justicia ambiental por distritos urbanos como base para las políticas y la intervención públicas

La problemática de las injusticias ambientales demanda diagnósticos por unidades espaciales adecuadas para la formación de decisiones públicas. De acuerdo con ello en esta contribución se pretende: a) abordar el análisis de la exposición potencial de ciertos grupos vulnerables de la población a una polución atmosférica excesiva en Madrid; b) explorar la idoneidad de diversas herramientas analíticas para tal fin; y c) proporcionar bases para el examen de las injusticias ambientales por distritos urbanos, dada su idoneidad para la gobernanza municipal. Metodológicamente se ha procedido a modelar la distribución espacial de dos contaminantes del aire en toda el área urbana, a partir de los datos de las estaciones de medición. Luego se ha medido la exposición de ciertos grupos demográficos vulnerables a alta contaminación y se ha sintetizado los resultados por distritos. Los hallazgos clarifican qué grupos vulnerables y con qué intensidad están más o menos expuestos a alta contaminación y en qué distritos, desvelando así inequidades ambientales y facilitando las deseables intervenciones correctoras.Esta trabajo se ha elaborado dentro del proyecto de investigación “Contaminación atmosférica urbana y justicia ambiental: metodología de evaluación y estudio de casos con sistemas de información geográfica”, financiado por el Ministerio de Economía y Competitividad de España, referencia CSO2011-26177

First record of the mangrove palm Nypa from the northeastern Ebro Basin, Spain : with taphonomic criteria to evaluate the drifting duration

Fossil fruits pertaining to the mangrove palm genus Nypa Steck, (Arecaceae, Arecales) were collected from a new plant-bearing assemblage in the Arguis Formation (Fm.), northeastern Ebro Basin (Arguis, Huesca Province, Spain). This formation is Bartonian to early Priabonian in age and comprises pro-delta and carbonate platform deposits. The new assemblage consists of nine specimens of fossil Nypa fruits and one monocotyledon leaf fragment. Over half of these fossil fruits are nearly-complete (i.e. with preserved mesocarps) while the other represent endocarps. From the point of view of morphology and size they resemble other European records of this genus. The type of remain preserved (fruits or endocarps), presence of abrasion, Teredo borings and sedimentary facies provide criteria to infer contrasting lengths of transport (drifting). However, they indicate in all cases that these fossil fruits were afloat in seawater for a considerable time. The discovery of Nypa fruits suggests a tropical-subtropical climate in the area, as well as the presence of a coastal environment and littoral forests during deposition. This interpretation corroborates previous findings from the nearby Eocene outcrops of the Catalan Central Depression (Eastern Pyrenees range)

Automatic language identification using deep neural networks

Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works. I. López-Moreno, J. González-Domínguez, P. Oldrich, D. R. Martínez, J. González-Rodríguez, "Automatic language identification using deep neural networks", IEEE International Conference on Acoustics, Speech, and Signal Processing ICASSP, Florence (Italy), 2014This work studies the use of deep neural networks (DNNs) to address automatic language identification (LID). Motivated by their recent success in acoustic modelling, we adapt DNNs to the problem of identifying the language of a given spoken utterance from short-term acoustic features. The proposed approach is compared to state-of-the-art i-vector based acoustic systems on two different datasets: Google 5M LID corpus and NIST LRE 2009. Results show how LID can largely benefit from using DNNs, especially when a large amount of training data is available. We found relative improvements up to 70%, in Cavg, over the baseline system

Spatial and temporal distribution of Mycobacterium tuberculosis complex infection in Eurasian badger (Meles meles) and cattle in Asturias, Spain

Trabajo presentado al: 69th Wildlife Disease Association and 14th European Wildlife Disease Association Conference. Cuenca, Spain. p. 66. 31 agosto-2 septiembre

Characterization of Ion Channels Involved in the Proliferative Response of Femoral Artery Smooth Muscle Cells

31 páginas, 6 figuras, adicionales 6 figuras y 3 tablas.[Objective]: Vascular smooth muscle cells (VSMCs) contribute significantly to occlusive vascular diseases by virtue of their ability to switch to a noncontractile, migratory, and proliferating phenotype. Although the participation of ion channels in this phenotypic modulation (PM) has been described previously, changes in their expression are poorly defined because of their large molecular diversity. We obtained a global portrait of ion channel expression in contractile versus proliferating mouse femoral artery VSMCs, and explored the functional contribution to the PM of the most relevant changes that we observed. [Methods and Results]: High-throughput real-time polymerase chain reaction of 87 ion channel genes was performed in 2 experimental paradigms: an in vivo model of endoluminal lesion and an in vitro model of cultured VSMCs obtained from explants. mRNA expression changes showed a good correlation between the 2 proliferative models, with only 2 genes, Kv1.3 and Kvβ2, increasing their expression on proliferation. The functional characterization demonstrates that Kv1.3 currents increased in proliferating VSMC and that their selective blockade inhibits migration and proliferation. [Conclusion]: These findings establish the involvement of Kv1.3 channels in the PM of VSMCs, providing a new therapeutical target for the treatment of intimal hyperplasia.This work was supported by Ministerio de Sanidad, Instituto de Salud Carlos III grants R006/009 (Red Heracles), FS041139-0 (M.R.), and PI041044 (J.R.L.-L.); Ministerio de Educacio´n y Ciencia grants BFU2004-05551 (M.T.P.-G.) and BFU2007-61524 (J.R.L.-L.); and Junta de Castilla y Leon grant GR242. Dr Moreno-Domínguez is a fellow of the Spanish Ministerio de Educacion y Ciencia.Peer reviewe

Technical viability study for behavioral monitoring of wildlife animals in Doñana: An 802.15.4 coverage study in a Natural Park

The study and monitoring of wildlife and in semi-freedom has always been a subject of great interest. In recent years the technology allows to design low cost systems that facilitate these tasks: microcontrollers, low-power wireless networks, sensors. GPS, satellite and VHF has been used for position tracking and localization of wildlife. Our aim is to design a low-cost system for local monitoring of wildlife (collar or harness) with local memory and remote access. It will use multiples sensors for behavioral and health monitoring and fuse the processed information locally to reduce the stored data, but allowing to be sporadically transmitted through wireless networks. This collar will be based on an embedded low-power microcontroller with 802.15.4 transceiver and a set of sensors to provide data (activity and health) of the animal under monitoring: accelerometers, compass, humidity, temperature, light, microphone, heart rhythm. This collar is called mote in wireless sensors network (WSN) terminology. Only when one mote is closer to an 802.15.4 mote and under request, the collar will dump the information to a host database server through the 802.15.4 network. In this paper we present a viability study of the WSN for Doñana Natural Park for different mote transmission powers, frequencies and distances for coverage. ZigBee and XBee mote has been proven.Consejo Superior de Investigaciones Científicas RDB-ICTS 39/201

Leptolide improves insulin resistance in diet-induced obese mice

Producción CientíficaType 2 diabetes (T2DM) is a complex disease linked to pancreatic beta-cell failure and insulin resistance. Current antidiabetic treatment regimens for T2DM include insulin sensitizers and insulin secretagogues. We have previously demonstrated that leptolide, a member of the furanocembranolides family, promotes pancreatic beta-cell proliferation in mice. Considering the beneficial effects of leptolide in diabetic mice, in this study, we aimed to address the capability of leptolide to improve insulin resistance associated with the pathology of obesity. To this end, we tested the hypothesis that leptolide should protect against fatty acid-induced insulin resistance in hepatocytes. In a time-dependent manner, leptolide (0.1 µM) augmented insulin-stimulated phosphorylation of protein kinase B (PKB) by two-fold above vehicle-treated HepG2 cells. In addition, leptolide (0.1 µM) counteracted palmitate-induced insulin resistance by augmenting by four-fold insulin-stimulated phosphorylation of PKB in HepG2 cells. In vivo, acute intraperitoneal administration of leptolide (0.1 mg/kg and 1 mg/kg) improved glucose tolerance and insulin sensitivity in lean mice. Likewise, prolonged leptolide treatment (0.1 mg/kg) in diet-induced obese mice improved insulin sensitivity. These effects were paralleled with an ~50% increased of insulin-stimulated phosphorylation of PKB in liver and skeletal muscle and reduced circulating pro-inflammatory cytokines in obese mice. We concluded that leptolide significantly improves insulin sensitivity in vitro and in obese mice, suggesting that leptolide may be another potential treatment for T2DM.This research has been funded by Sociedad Española de Diabetes (Ayudas Investigación Básica 2014), Salud Castilla y León (BIO/VA40/15)Ministerio de Economía y Competitividad, (SAF2014-58702-C2-1-R),(SAF2014-58702-C2-2-R