5,538 research outputs found

    Constraints on unparticle physics from the gttˉgt\bar t anomalous coupling

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    We study the impact of unparticle physics to the chromomagnetic dipole moment (CMDM) of the top quark. We compute the effect induced by unparticle operators of scalar and vector nature coupled to fermions on the CMDM. We find that this dipole moment is sensitive to the scale dimensions dud_u of the unparticle and the new couplings of the respective effective operators. Using the bounds imposed on the CMDM by low-energy precision and Tevatron measurements we derive indirect limits on the unparticle parameter space. In particular, we find that the scalar-unparticle operator contribution fulfills both constraints for most of the unparticle parameter space, while the low-energy precision bound on the CMDM excludes a vector-unparticle contribution for low values of respective scale dimension dud_u.Comment: 8 pages, 4 figure

    Impact of an intermittent and localized cooling intervention on skin temperature, sleep quality and energy expenditure in free-living, young, healthy adults

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    Where people live and work together it is not always possible to modify the ambient temperature; ways must therefore be found that allow individuals to feel thermally comfortable in such settings. The Embr Wave (R) is a wrist-worn device marketed as a 'personal thermostat' that can apply a local cooling stimulus to the skin. The aim of the present study was to determine the effect of an intermittent mild cold stimulus of 25 degrees C for 15-20 s every 5 min over 3.5 days under free-living conditions on 1) skin temperature, 2) perception of skin temperature, 3) sleep quality and 4) resting energy expenditure (REE) in young, healthy adults. Ten subjects wore the device for 3.5 consecutive days. This intervention reduced distal skin temperature after correcting for personal ambient temperature (P = 0.051). Thus, this intermittent mild cold regime can reduce distal skin temperature, and wearing it under free-living conditions for 3.5 days does not seem to impair the perception of skin temperature and sleep quality or modify REE.The study was funded by the Spanish Ministry of Economy and Competitiveness via the Fondo de Investigacion Sanitaria del Instituto de Salud Carlos III (PI13/01393 and CB16/10/00239) and PTA 12264-I, Retos de la Sociedad (DEP2016-79512-R), and European Regional Development Funds (ERDF). Other funders included the Spanish Ministry of Education (FPU 16/05159, 15/04059 and 19/02326), the Fundacion Iberoamericana de Nutricion (FINUT), the Redes Tematicas De Investigacion Cooperativa RETIC (Red SAMID RD16/0022), the AstraZeneca Health Care Foundation, the University of Granada Plan Propio de Investigacion 2016 (Excellence actions: Unit of Excellence on Exercise, Nutrition and Health [UCEENS]), and by the Junta de Andalucia, Consejeria de Conocimiento, Investigacion y Universidades (ERDF, SOMM17/6107/UGR). AMT was supported by Seneca Foundation through grant 19899/GERM/15 and the Ministry of Science Innovation and Universities RTI2018-093528-B-I0, as well as DJP (MINECO; RYC-2014-16938). BMT was supported by an individual postdoctoral grant from the Fundacion Alfonso Martin Escudero. We thank Dr. Matt Smith of Embr Labs Inc. for configuring the Embr Wave (R) devices used in this experiment

    A measurement setup and automated calculation method to determine the charge injection capacity of implantable microelectrodes

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    Producción CientíficaThe design of safe stimulation protocols for functional electrostimulation requires knowledge of the “maximum reversible charge injection capacity” of the implantable microelectrodes. One of the main difficulties encountered in characterizing such microelectrodes is the calculation of the access voltage Va. This paper proposes a method to calculate Va that does not require prior knowledge of the overpotential terms and of the electrolyte (or excitable tissue) resistance, which is an advantage for in vivo electrochemical characterization of microelectrodes. To validate this method, we compare the calculated results with those obtained from conventional methods for characterizing three flexible platinum microelectrodes by cyclic voltammetry and voltage transient measurements. This paper presents the experimental setup, the required instrumentation, and the signal processing.Ministerio de Economía y Competitividad ( Research project DPI2016-80391-C3-3-R

    Histopatología de la Hepatitis Viral Crónica C, Pinar del Río, enero 2002-julio 2008 / Histopathology of Chronic Viral Hepatitis-C, Pinar del Rio. January 2002- July 2008

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    A pesar de ser la hepatitis por virus C (HCVC) un problema de salud en el mundo y ser la causa más frecuente de hepatitis crónica, cirrosis hepática y carcinoma hepatocelular no se dispone de un sistema de puntaje práctico para el diagnóstico histopatológico.Objetivos: Incrementar el desempeño de los patólogos en el diagnóstico de la HCVC en el Hospital "Abel Santamaría Cuadrado" desde enero 2002 hasta julio 2008.Diseño: Se realizó una innovación tecnológica con la confección de un libro de esquemas procesados electrónicamente y se estudiaron las biopsias con HCV mediante un diseño descriptivo y transversal. Sujetos y Método.Universo: 236 biopsias diagnosticadas como HCV. Muestra: 117 biopsias diagnosticadas como HCVC (el total en el período). Se determinó edad, sexo, tipo de lesión histológica y correspondencia diagnóstica entre el grado de lesión histológica y el estadio de fibrosis con la edad. Se usó la Estadística Descriptiva para resumir variables categóricas y cuantitativas continuas, cálculos de comprobación de frecuencias y/o asociaciones de variables X², OR al 95 % de certeza. Resultados. Se elaboró un sistema de dibujos histológicos representativos de la clasificación de las hepatitis virales crónicas. La HCVC fue más frecuente entre 35-54 años, sexo femenino, con actividad necroinflamatoria moderada que alcanzó el 60.6 %. La fibrosis severa se presentó preferentemente entre 35 y 44 años. Conclusión. Se comprobó que el sistema de dibujos confeccionados posibilita una mejor estandarización del diagnóstico en un colectivo y facilita el aprendizaje de la entidad. Palabras clave: hepatitis viral humana, fibrosis, aprendizaje.ABSTRACT Despite being hepatitis caused by C virus (HCV) a worldwide health problem and the most frequent cause of chronic hepatitis, liver cirrhosis and hepatocelular carcinoma, a practical score system to perform the histopathologic diagnosis does not exist. Objective: To increase the competence of pathologists in the diagnosis of HCV at "Abel Santamaria Cuadrado" University Hospital from January 2002 to July 2008. Design: A technological innovation was created writing a book with electronically- processed diagrams and the study of HCV-biopsies by means of a descriptive and cross-sectional design. Subjects and Method: Universe: 236 biopsies with the diagnosis of HCV. Sample: 117 biopsies having the diagnosis of Chronic- HCV (the total during the period). Age, sex, type of histological lesion; diagnostic correspondence, the degree of the lesion and stage of the fibrosis in respect of the age were considered. Descriptive Statistics was used to sum up the categorical and continuing quantitative variables and the verification of frequencies through calculation and/or association of variables X2, OR. Results: A system of representative histological draws for the classification of chronic viral hepatitis (Ishak, 1995) was created. Chronic-HCV was more frequent between ages 35-54, female sex, and moderate necro-inflammatory activityreached up to 60.6% between 35 and 44 years old. Conclusion: It was confirmed that the system of draws makes possible a better standardization of the diagnosis in teams and provides a more suitable learning of the disease.Key words: human viral hepatitis, fibrosis, learning

    Histopatología de la Hepatitis Viral Crónica C, Pinar del Río, enero 2002-julio 2008 / Histopathology of Chronic Viral Hepatitis-C, Pinar del Rio. January 2002- July 2008

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    A pesar de ser la hepatitis por virus C (HCVC) un problema de salud en el mundo y ser la causa más frecuente de hepatitis crónica, cirrosis hepática y carcinoma hepatocelular no se dispone de un sistema de puntaje práctico para el diagnóstico histopatológico.Objetivos: Incrementar el desempeño de los patólogos en el diagnóstico de la HCVC en el Hospital "Abel Santamaría Cuadrado" desde enero 2002 hasta julio 2008.Diseño: Se realizó una innovación tecnológica con la confección de un libro de esquemas procesados electrónicamente y se estudiaron las biopsias con HCV mediante un diseño descriptivo y transversal. Sujetos y Método.Universo: 236 biopsias diagnosticadas como HCV. Muestra: 117 biopsias diagnosticadas como HCVC (el total en el período). Se determinó edad, sexo, tipo de lesión histológica y correspondencia diagnóstica entre el grado de lesión histológica y el estadio de fibrosis con la edad. Se usó la Estadística Descriptiva para resumir variables categóricas y cuantitativas continuas, cálculos de comprobación de frecuencias y/o asociaciones de variables X², OR al 95 % de certeza. Resultados. Se elaboró un sistema de dibujos histológicos representativos de la clasificación de las hepatitis virales crónicas. La HCVC fue más frecuente entre 35-54 años, sexo femenino, con actividad necroinflamatoria moderada que alcanzó el 60.6 %. La fibrosis severa se presentó preferentemente entre 35 y 44 años. Conclusión. Se comprobó que el sistema de dibujos confeccionados posibilita una mejor estandarización del diagnóstico en un colectivo y facilita el aprendizaje de la entidad. Palabras clave: hepatitis viral humana, fibrosis, aprendizaje.ABSTRACT Despite being hepatitis caused by C virus (HCV) a worldwide health problem and the most frequent cause of chronic hepatitis, liver cirrhosis and hepatocelular carcinoma, a practical score system to perform the histopathologic diagnosis does not exist. Objective: To increase the competence of pathologists in the diagnosis of HCV at "Abel Santamaria Cuadrado" University Hospital from January 2002 to July 2008. Design: A technological innovation was created writing a book with electronically- processed diagrams and the study of HCV-biopsies by means of a descriptive and cross-sectional design. Subjects and Method: Universe: 236 biopsies with the diagnosis of HCV. Sample: 117 biopsies having the diagnosis of Chronic- HCV (the total during the period). Age, sex, type of histological lesion; diagnostic correspondence, the degree of the lesion and stage of the fibrosis in respect of the age were considered. Descriptive Statistics was used to sum up the categorical and continuing quantitative variables and the verification of frequencies through calculation and/or association of variables X2, OR. Results: A system of representative histological draws for the classification of chronic viral hepatitis (Ishak, 1995) was created. Chronic-HCV was more frequent between ages 35-54, female sex, and moderate necro-inflammatory activityreached up to 60.6% between 35 and 44 years old. Conclusion: It was confirmed that the system of draws makes possible a better standardization of the diagnosis in teams and provides a more suitable learning of the disease.Key words: human viral hepatitis, fibrosis, learning

    Experimental validation of Lyot stop apodization in ground-based coronagraphy

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    ABSTRACT We show that the use of apodizing functions at the coronagraph Lyot plane may be useful for improving the image contrast of ground-based coronagraphs. An experimental set-up consisting of a tip–tilt mirror, a coronagraph and a low-noiseEMCCDcamerawas implemented at theWilliam Herschel Telescope. Images were taken in the I band, which meant that the D/r0 value was around 10. Experimental results confirm that, for moderately aberrated wavefronts, our instrument works as theoretically expected, and that the contrast value attained is high enough to provide direct detection of faint companions.This research was supported by the Ministerio de Economía y Competitividad under project FIS2012-31079 and the Fundación Séneca of Murcia under projects 15419/PI/10 and 15345/PI/10

    Nuclear astrophysics with radioactive ions at FAIR

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    The nucleosynthesis of elements beyond iron is dominated by neutron captures in the s and r processes. However, 32 stable, proton-rich isotopes cannot be formed during those processes, because they are shielded from the s-process flow and r-process beta-decay chains. These nuclei are attributed to the p and rp process. For all those processes, current research in nuclear astrophysics addresses the need for more precise reaction data involving radioactive isotopes. Depending on the particular reaction, direct or inverse kinematics, forward or time-reversed direction are investigated to determine or at least to constrain the desired reaction cross sections. The Facility for Antiproton and Ion Research (FAIR) will offer unique, unprecedented opportunities to investigate many of the important reactions. The high yield of radioactive isotopes, even far away from the valley of stability, allows the investigation of isotopes involved in processes as exotic as the r or rp processes

    Crecimiento de las tilapias oreochromis niloticus en cultivo monosexual y ambos sexos, en sistemas de producción semi – intensivos

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    Target. To compare the population parameters of Oreochromis niloticus tilapias grown in Monosexual and Both-sex cultures in semi-intensive production systems. Materials and methods. To determine which treatment obtained the highest growth, physical-chemical factors (Dissolved Oxygen, Temperature) and population parameters (Accumulated Growth, Survival and Feed Conversion Factor) were taken. Collecting these data for 25 days where the Tilapia Oreochromis niloticus had an initial weight of 77.43gr in both treatments. Results. According to the results obtained in the experiment, the monosexual treatment acquired a final growth of 135.42gr, obtaining an average of 57.99 gr, while the treatment of both sexes reached a final growth of 112.73gr, achieving an average of 35.3 gr. Conclution. The monosexual treatment gained greater size and biomass in less time since they only dedicated themselves to feeding, on the other hand in the treatment of both sexes they gained little biomass since the ingested food was used for the preparation of sexual maturation and thus enter the reproductive stage, which decreased its growth rate, when applying the statistical analysis it was found that p>0.05 alleging that the growth of Tilapia Oreochromis niloticus is greater when only males are cultivated.  Objetivo. Comparar los parámetros poblacionales de las tilapias Oreochromis niloticus que crecen en cultivos Monosexuales y Ambos sexos en sistemas de producción semi-intensivos. Materiales y Métodos. Para determinar que tratamiento obtuvo mayor crecimiento se realizó la toma de factores físico-químicos (Oxígeno Disuelto, Temperatura) y parámetros poblacionales (Crecimiento Acumulado, Sobrevivencia y Factor de Conversión Alimenticia). Recolectando estos datos durante 25 días donde las Tilapias Oreochromis niloticus tuvieron un peso inicial de 77.43gr en ambos tratamientos. Resultados. Según los resultados obtenidos en el experimento, el tratamiento monosexual adquirió un crecimiento final de 135.42gr obteniendo como promedio 57.99 gr en cambio el tratamiento de ambos sexos alcanzó un crecimiento final de 112.73gr logrando un promedio de 35.3 gr. Conclusión. El tratamiento monosexual gano mayor tamaño y biomasa en menor tiempo dado que estos solamente se dedicaron  a alimentarse, en cambio en el tratamiento de ambos sexos gano poca biomasa ya que el alimento ingerido lo ocuparon para la preparación de la maduración sexual y así entrar a la etapa de reproducción, lo que disminuyo su velocidad de crecimiento, al aplicar los análisis estadísticos se encontró que p>0.05 alegando que el crecimiento de las Tilapias Oreochromis niloticus es mayor cuando solo se cultivan machos

    Plasma irisin depletion under energy restriction is associated with improvements in lipid profile in metabolic syndrome patients

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    OBJECTIVE: A recently discovered myokine, irisin, may have an important role in energy metabolism. This study aimed to evaluate the relationship between this hormone and the lipid profile of patients with metabolic syndrome (MetS) following a hypocaloric diet. DESIGN: Ninety-three Caucasian adults (52 men/41 women) diagnosed with MetS followed an 8-week-long energy-restricted programme (-30% of the energy requirements). Anthropometric measurements, biochemical markers and plasma irisin levels were analysed before and after the nutritional intervention. RESULTS: Global plasma irisin levels were significantly reduced at the end of the study (-72.0 +/- 100.9 ng/ml, P < 0.001) accompanying the weight loss (-6.9%). The depletion of irisin significantly correlated with changes in some atherogenic-related variables: total cholesterol (B = 0.106, P = 0.018), total cholesterol/high-density lipoprotein cholesterol ratio (B = 0.002, P = 0.036), low-density lipoprotein cholesterol (B = 0.085, P = 0.037) and apolipoprotein B (B = 0.052, P = 0.002), independently of changes in body weight. CONCLUSIONS: An association between the reduction in plasma irisin levels and the depletion of important lipid metabolism biomarkers was observed in patients with MetS undergoing an energy-restricted programme
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