337 research outputs found
Kinetics of Intramolecular Chemical Exchange by Initial Growth Rates of Spin Saturation Transfer Difference Experiments (SSTD NMR)
We report here the Initial Growth Rates SSTD NMR method, as a new powerful tool to obtain the kinetic parameters of intramolecular chemical exchange in challenging small organic and organometallic molecules
Flavour physics constraints in the BMSSM
We study the implications of the presence of the two leading-order,
non-renormalizable operators in the Higgs sector of the MSSM to flavour physics
observables. We identify the constraints of flavour physics on the parameters
of the BMSSM when we: a) focus on a region of parameters for which electroweak
baryogenesis is feasible, b) use a CMSSM-like parametrization, and c) consider
the case of a generic NUHM-type model. We find significant differences as
compared to the standard MSSM case.Comment: 22 pages, 7 figure
Gapped continuum Kaluza-Klein spectrum
We consider a warped ve-dimensional model with an ultraviolet (UV) brane
and, on top of the Standard Model isolated modes, continua of KK modes with different
mass gaps for all particles: gauge bosons, fermions, graviton, radion and Higgs boson. The
model can be considered as a modelization in ve dimensions of gapped unparticles. The
ve dimensional metric has a singularity, at a finite (infinite) value of the proper (conformal)
coordinate, which is admissible as it supports finite temperature in the form of a black
hole horizon. An infrared (IR) brane, with particular jumping conditions, is introduced
to trigger correct electroweak breaking. The gravitational metric is AdS5 near the UV
brane, to solve the hierarchy problem with a fundamental Planck scale, and linear, in
conformal coordinates, near the IR, as in the linear dilaton and ve-dimensional clockwork
models. The branes, and singularity, distances are fixed, à la Goldberger-Wise, by a bulk
scalar field with brane potentials explicitly breaking the conformal symmetry. The bosonic
continuum of KK modes with the smallest mass gap are those of gauge bosons, and so they
are the most likely produced at the LHC. Mass gaps of the continuum of KK fermions
do depend on their localization in the extra dimension. We have computed the spectral
functions, and arbitrary Green's functions, and shown how they can modify some Standard
Model processes.The work of EM is supported by the Spanish MINEICO under Grant FIS2017-85053-C2-1-P, by the Junta de Andalucía under Grant FQM-225, by
the Consejería de Conocimiento, Investigación y Universidad of the Junta de Andalucía and
European Regional Development Fund (ERDF) under Grant SOMM17/6105/UGR, and by
the Spanish Consolider Ingenio 2010 Programme CPAN under Grant CSD2007-00042. The
research of EM is also supported by the Ramón y Cajal Program of the Spanish MINEICO
under Grant RYC-2016-20678. The work of MQ is partly supported by Spanish MINEICO
(Grant FPA2017-88915-P), by the Catalan Government under Grant 2017SGR1069, and
by Severo Ochoa Excellence Program of MINEICO (Grant SEV-2016-0588)
Decoupling property of the supersymmetric Higgs sector with four doublets
In supersymmetric standard models with multi Higgs doublet fields,
selfcoupling constants in the Higgs potential come only from the D-terms at the
tree level. We investigate the decoupling property of additional two heavier
Higgs doublet fields in the supersymmetric standard model with four Higgs
doublets. In particular, we study how they can modify the predictions on the
quantities well predicted in the minimal supersymmetric standard model (MSSM),
when the extra doublet fields are rather heavy to be measured at collider
experiments. The B-term mixing between these extra heavy Higgs bosons and the
relatively light MSSM-like Higgs bosons can significantly change the
predictions in the MSSM such as on the masses of MSSM-like Higgs bosons as well
as the mixing angle for the two light CP-even scalar states. We first give
formulae for deviations in the observables of the MSSM in the decoupling region
for the extra two doublet fields. We then examine possible deviations in the
Higgs sector numerically, and discuss their phenomenological implications.Comment: 26 pages, 24 figures, text sligtly modified,version to appear in
Journal of High Energy Physic
The Light Stop Scenario from Gauge Mediation
In this paper we embed the light stop scenario, a MSSM framework which
explains the baryon asymmetry of the universe through a strong first order
electroweak phase transition, in a top-down approach. The required low energy
spectrum consists in the light SM-like Higgs, the right-handed stop, the
gauginos and the Higgsinos while the remaining scalars are heavy. This spectrum
is naturally driven by renormalization group evolution starting from a heavy
scalar spectrum at high energies. The latter is obtained through a
supersymmetry-breaking mix of gauge mediation, which provides the scalars
masses by new gauge interactions, and gravity mediation, which generates
gaugino and Higgsino masses. This supersymmetry breaking also explains the \mu\
and B_\mu\ parameters necessary for electroweak breaking and predicts small
tri-linear mixing terms A_t in agreement with electroweak baryogenesis
requirements. The minimal embedding predicts a Higgs mass around its
experimental lower bound and by a small extension higher masses m_H\lesssim 127
GeV can be accommodated.Comment: 20 pages, 3 figures; v2: changes in the conventions; v3: more details
on the Higgs mass prediction, version published in JHE
CP violation Beyond the MSSM: Baryogenesis and Electric Dipole Moments
We study electroweak baryogenesis and electric dipole moments in the presence
of the two leading-order, non-renormalizable operators in the Higgs sector of
the MSSM. Significant qualitative and quantitative differences from MSSM
baryogenesis arise due to the presence of new CP-violating phases and to the
relaxation of constraints on the supersymmetric spectrum (in particular, both
stops can be light). We find: (1) spontaneous baryogenesis, driven by a change
in the phase of the Higgs vevs across the bubble wall, becomes possible; (2)
the top and stop CP-violating sources can become effective; (3) baryogenesis is
viable in larger parts of parameter space, alleviating the well-known
fine-tuning associated with MSSM baryogenesis. Nevertheless, electric dipole
moments should be measured if experimental sensitivities are improved by about
one order of magnitude.Comment: 33 pages, 6 figure
Cosmological phase transitions in warped space: gravitational waves and collider signatures
We study the electroweak phase transition within a 5D warped model including
a scalar potential with an exponential behavior, and strong back-reaction over the metric,
in the infrared. By means of a novel treatment of the superpotential formalism, we explore
parameter regions that were previously inaccessible. We nd that for large enough values
of the t'Hooft parameter (e.g. N = 25) the holographic phase transition occurs, and it
can force the Higgs to undergo a rst order electroweak phase transition, suitable for
electroweak baryogenesis. The model exhibits gravitational waves and colliders signatures.
It typically predicts a stochastic gravitational wave background observable both at the
Laser Interferometer Space Antenna and at the Einstein Telescope. Moreover the radion
tends to be heavy enough such that it evades current constraints, but may show up in
future LHC runs.The work of EM is supported by the Spanish MINEICO under
Grant FPA2015-64041-C2-1-P and FIS2017-85053-C2-1-P, by the Junta de Andaluc a under
Grant FQM-225, by the Basque Government under Grant IT979-16, and by the Spanish
Consolider Ingenio 2010 Programme CPAN (CSD2007-00042). The research of EM is also
supported by the Ram on y Cajal Program of the Spanish MINEICO, and by the Universidad
del Pa s Vasco UPV/EHU, Bilbao, Spain, as a Visiting Professor. GN is supported
by the Swiss National Science Foundation (SNF) under grant 200020-168988. The work
of MQ is partly supported by Spanish MINEICO under Grant CICYT-FEDER-FPA2014-
55613-P and FPA2017-88915-P, by the Severo Ochoa Excellence Program of MINEICO
under Grant SEV-2016-0588, and by CNPq PVE fellowship project 405559/2013-5
Tobacco smoking-associated genome-wide DNA methylation changes in the EPIC study.
Epigenetic changes may occur in response to environmental stressors, and an altered epigenome pattern may represent a stable signature of environmental exposure
Caracterización bioquímica de hojas de clones de Theobroma cacao y su relación con los tricomas
Título en ingles: Biochemical characterization of leaves in Theobroma cacao clones and its relation with trichomesTheobroma cacao L. es un cultivo de gran importancia por sus posibles aplicaciones en la farmacia y la agricultura. Contiene metabolitos que resultan de gran interés por sus funciones biológicas naturales en la respuesta de la planta a los diferentes tipos de estrés, tanto bióticos como abióticos. La presencia, tipo y concentración de los metabolitos (primarios y secundarios) pueden variar de acuerdo al genotipo analizado y se pueden acumular en estructuras asociadas a la arquitectura de la hoja como son los tricomas. El objetivo de este trabajo fue caracterizar 26 clones del banco de germoplasma de Padrón, INIA-Miranda, Estado Miranda, Venezuela y estudiar la relación existente entre los indicadores bioquímicos y el número de tricomas. Se determinó el contenido de compuestos fenólicos, proteínas solubles, prolina libre, carbohidratos totales, ligninas, el número de tricomas y la relación existente entre ellos. Los resultados mostraron que en el espacio bidimensional que explica el 46,68% de la variabilidad total, se definieron cinco grupos homogéneos: diez clones se asociaron con el máximo gradiente de prolina, carbohidratos totales y contenido de ligninas, nueve con alto contenido de proteínas y fenoles y siete con mayor número de tricomas en hojas. Se comprobó que el número de tricomas no se relacionó con la concentración de compuestos fenólicos.Los clones de cacao del tipo forastero mostraron mayor concentración de fenoles totales y carbohidratos, en tanto que los trinitarios presentaron mayor concentración de proteínas y prolina.Theobroma cacao L. is a crop of major importance for their potential applications in pharmacy and agriculture. It contains metabolites that are of great interest for its natural biological functions in plant response to different types of stress, both biotic and abiotic. The presence, type and concentration of both primary and secondary metabolites may vary depending on the genotype analyzed and these compounds can accumulate in the architecture associated structures such as leaf trichomes. The aim of this study was to characterize 26 clones of the germplasm bank of Padrón, INIA-Miranda, Miranda State, Venezuela and study the relationship between biochemical indicators assessed and the number of trichomes. The content of phenolic compounds, soluble protein, free proline, total carbohydrates, lignins, the number of trichomes and the relationship between all traits was determined. The results showed that in the two dimensional space explained 46.68% of the variability, five homogeneous groups were defined: 10 clones were associated with the maximum gradient of proline, total carbohydrate and lignin content. Nine clones were associated with high content of phenols and a group of seven clones with the highest number of trichomes on leaves. It was found that the number of trichomes was not related to the concentration of phenolic compounds. The clones of Forastero cocoa type showed higher concentration of total phenols and carbohydrates, meanwhile the Trinitario type presented higher concentration of proteins and prolina.Key words: principal components analysis; phenols; proline; proteins; carbohydrates
Intake of individual fatty acids and risk of prostate cancer in the European prospective investigation into cancer and nutrition
The associations of individual dietary fatty acids with prostate cancer risk have not been examined comprehensively. We examined the prospective association of individual dietary fatty acids with prostate cancer risk overall, by tumor subtypes, and prostate cancer death. 142,239 men from the European Prospective Investigation into Cancer and Nutrition who were free from cancer at recruitment were included. Dietary intakes of individual fatty acids were estimated using center-specific validated dietary questionnaires at baseline and calibrated with 24-hour recalls. Multivariable Cox regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). After an average follow-up of 13.9 years, 7,036 prostate cancer cases and 936 prostate cancer deaths were ascertained. Intakes of individual fatty acids were not related to overall prostate cancer risk. There was evidence of heterogeneity in the association of some short chain saturated fatty acids with prostate cancer risk by tumor stage (Pheterogeneity <0.015), with a positive association with risk of advanced stage disease for butyric acid (4:0; HR1SD =1.08; 95%CI=1.01-1.15; P-trend=0.026). There were no associations with fatal prostate cancer, with the exception of a slightly higher risk for those who consumed more eicosenoic acid (22:1n-9c; HR1SD =1.05; 1.00-1.11; P-trend=0.048) and eicosapentaenoic acid (20:5n-3c; HR1SD =1.07; 1.00-1.14; P-trend=0.045). There was no evidence that dietary intakes of individual fatty acids were associated with overall prostate cancer risk. However, a higher intake of butyric acid might be associated with a higher risk of advanced, whereas intakes of eicosenoic and eicosapentaenoic acids might be positively associated with fatal prostate cancer risk. This article is protected by copyright. All rights reserved
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