109 research outputs found
The reaction to working class unrest, 1911-1914.
- Author
- Publication venue
- 'University of Sheffield Conference Proceedings'
- Publication date
- 01/01/1976
- Field of study
The period 1911-14 has, until late, been largely ignored by historians, and, like so many other periods, even when it has been covered, there has been little attempt to investigate the attitudes of the people of the time to the events. This thesis endeavours to compensate for this, at least to a small degree. It examines the class structure of the period, and then looks at the working class unrest of the time from the eyes of the community. It was an especially strike-prone age and for the first time, there were national stoppages and sympathetic walk-outs, with the threat of Syndicalism lurking in the background. Some believed that revolution was imminent. Unfortunately, the sources have been limited by the availability of material, but, nevertheless, the thesis represents the nearest approximation possible to public opinion. It reveals that the nation did not have a single view on any of the major disputes, and that the split was not entirely along •political lines. Some Tories were quite sympathetic to the working class, whilst certain Liberals were extremely traditional and authoritarian. Moreover, attitudes did not remain constant, but changed with events. Finally, the results of this study are looked at in relation to several theories on public opinion, and, as such, virtually represent a case study for sociological theorists
Demand management and stock control in the licensed trade; is it so simple?
- Publication venue
- Institute of Operations Management
- Publication date
- 01/10/2000
- Field of study
There are about 60,000 public houses in the UK and more than
half of these operate as small businesses. By 1990 businesses
with less than 200 employees accounted for nearly a third of
total UK employment [6] with the consequential effect that
supply of goods from supplier through producer to customer
using small businesses has become more significant over time.
While the large brewers operate their houses by employing
well trained managers and other staff, most of the proprietors
of the small businesses have little or no formal training
themselves, and have minimal knowledge of effective stock
control. Moreover, they are unaware of any need for such
knowledge. This article uses the comparative case study
approach to illustrate demand management and stock control
in a leased public house run as a small business, and a brewery
managed public house
None for the road: an attempt to identify the responsibility for ethical alcohol service
- Publication venue
- Publication date
- 01/09/2006
- Field of study
The social role of accounting: views and perceptions of the accounting community in Libya towards corporate social responsibility and accountability
- Publication venue
- Publication date
- 01/09/2005
- Field of study
The paper explores views and perceptions amongst members of the accounting community in Libya regarding the perceived basic features of the current corporate reporting and disclosure practices of the Libyan Business Organisations (LBOs). Extending these practices to embrace reporting and disclosure of social and environmental related information (CSR), and the extent to which notions of corporate social responsibility and accountability are acceptable in Libya are examined.
Five groups of users of published accounts in Libya participated in the study, including academic accountants, financial managers (or accountants), government officials, bank credit officers and external auditors. A questionnaire survey of the 438 participants, drawing on the Al-khater and Naser (2003) study, was employed as the main data collection method.
The findings demonstrate that currently most LBOs communicate limited information to a limited set of stakeholders. The disclosure of more social and environmental information was widely accepted and viewed as potentially leading to some beneficial socio-economic effects at the macro level. There was general agreement that the LBOs’ annual reports should reflect the interaction between their operations and the society in which they operate, recognizing the right of different stakeholders to information about the actions for which LBOs could be held responsible. The Law was viewed as the key source of establishing such responsibilities rather than professional guidelines
The population of merging compact binaries inferred using gravitational waves through GWTC-3
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- CASENTINI CLAUDIO
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- Engelby E.
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- ERRICO Luigi
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- Fiumara V.
- Flaminio R.
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- GRADO ANIELLO
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- Publication venue
- Publication date
- 23/02/2022
- Field of study
We report on the population properties of 76 compact binary mergers detected with gravitational waves below a false alarm rate of 1 per year through GWTC-3. The catalog contains three classes of binary mergers: BBH, BNS, and NSBH mergers. We infer the BNS merger rate to be between 10 Gpc−3yr−1 and 1700 Gpc−3yr−1 and the NSBH merger rate to be between 7.8 Gpc−3yr−1 and 140 Gpc−3yr−1 , assuming a constant rate density versus comoving volume and taking the union of 90% credible intervals for methods used in this work. Accounting for the BBH merger rate to evolve with redshift, we find the BBH merger rate to be between 17.9 Gpc−3yr−1 and 44 Gpc−3yr−1 at a fiducial redshift (z=0.2). We obtain a broad neutron star mass distribution extending from 1.2−0.2+0.1M⊙ to 2.0−0.3+0.3M⊙. We can confidently identify a rapid decrease in merger rate versus component mass between neutron star-like masses and black-hole-like masses, but there is no evidence that the merger rate increases again before 10 M⊙. We also find the BBH mass distribution has localized over- and under-densities relative to a power law distribution. While we continue to find the mass distribution of a binary's more massive component strongly decreases as a function of primary mass, we observe no evidence of a strongly suppressed merger rate above ∼60M⊙. The rate of BBH mergers is observed to increase with redshift at a rate proportional to (1+z)κ with κ=2.9−1.8+1.7 for z≲1. Observed black hole spins are small, with half of spin magnitudes below χi≃0.25. We observe evidence of negative aligned spins in the population, and an increase in spin magnitude for systems with more unequal mass ratio
Search for gravitational-lensing signatures in the full third observing run of the LIGO-Virgo network
- Author
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aiello Lorenzo
- Ain A.
- Ajith Parameswaran
- Akutsu Tomotada
- Albanesi S.
- Alfaidi R. A.
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Amato Alex
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
- Antelis Javier M.
- Antier Sarah
- Antonio Font Roda Jose
- Apostolatos T.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Arif Shaikh Md
- Aritomi Naoki
- Arnaud Nicolas
- Arogeti M.
- Aronson S. M.
- Arène M.
- Asada Hideki
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
- Aston S. M.
- Astone Pia
- Aubin Florian
- Babak Stanislav
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- Zeidler Simon
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- Zhan M.
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- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
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- Árpád Gergely László
- 劉 國欽
- 曹周键
- 王谨
- 都丸 隆行
- Publication venue
- Publication date
- 01/04/2023
- Field of study
Gravitational lensing by massive objects along the line of sight to the source causes distortions of gravitational wave-signals; such distortions may reveal information about fundamental physics, cosmology and astrophysics. In this work, we have extended the search for lensing signatures to all binary black hole events from the third observing run of the LIGO--Virgo network. We search for repeated signals from strong lensing by 1) performing targeted searches for subthreshold signals, 2) calculating the degree of overlap amongst the intrinsic parameters and sky location of pairs of signals, 3) comparing the similarities of the spectrograms amongst pairs of signals, and 4) performing dual-signal Bayesian analysis that takes into account selection effects and astrophysical knowledge. We also search for distortions to the gravitational waveform caused by 1) frequency-independent phase shifts in strongly lensed images, and 2) frequency-dependent modulation of the amplitude and phase due to point masses. None of these searches yields significant evidence for lensing. Finally, we use the non-detection of gravitational-wave lensing to constrain the lensing rate based on the latest merger-rate estimates and the fraction of dark matter composed of compact objects
Search for eccentric black hole coalescences during the third observing run of LIGO and Virgo
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Acernese F.
- Ackley Kendall
- Adamcewicz C.
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal D.
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Almualla M.
- Altin Paul
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Anand S.
- Ananyeva A.
- Andersen R.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
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- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anne Bizouard Marie
- Ansoldi S.
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- Antier Sarah
- Antonio Font Roda Jose
- Aoumi M.
- Apostolatos T.
- Appavuravther E. Z.
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- Aronson Scott
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- tiwari shubhanshu
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- UCHIKATA NAMI.
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- Vahlbruch Henning
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- Wysocki Daniel
- Xiao Liting
- Xu Victoria
- Yaala M. Ben
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- Yakovlev Alexey
- Yamamoto Hiroaki
- Yamamoto Kazuhiro
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- Yamamoto Takahiro
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- Yamamura S.
- Yamazaki Ryo
- Yan S.
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- Yang Y. -C.
- Yang Yang
- Yang Yi
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- Yarbrough Zach
- Yeh S. -W.
- Yelikar A. B.
- Yeung S. M. C.
- Yeung T. Y.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yu Hang
- Yuzurihara Hirotaka
- Zadrożny A.
- Zahoor Jan Aasim
- Zannelli A. J.
- Zanolin M.
- Zeeshan M.
- Zelenova T.
- Zendri J. -P.
- Zevin Michael
- Zhang Jue
- Zhang L.
- Zhang Rui
- Zhang T.
- Zhang Ya
- Zhang Yanqi
- Zhao C.
- Zhao Yue
- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhou R.
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Zweizig John
- Álvarez-López S.
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/08/2023
- Field of study
Despite the growing number of confident binary black hole coalescences observed through gravitational waves so far, the astrophysical origin of these binaries remains uncertain. Orbital eccentricity is one of the clearest tracers of binary formation channels. Identifying binary eccentricity, however, remains challenging due to the limited availability of gravitational waveforms that include effects of eccentricity. Here, we present observational results for a waveform-independent search sensitive to eccentric black hole coalescences, covering the third observing run (O3) of the LIGO and Virgo detectors. We identified no new high-significance candidates beyond those that were already identified with searches focusing on quasi-circular binaries. We determine the sensitivity of our search to high-mass (total mass M>70 M⊙) binaries covering eccentricities up to 0.3 at 15 Hz orbital frequency, and use this to compare model predictions to search results. Assuming all detections are indeed quasi-circular, for our fiducial population model, we place an upper limit for the merger rate density of high-mass binaries with eccentricities 0<e≤0.3 at 0.33 Gpc−3 yr−1 at 90\% confidence level
Ultralight vector dark matter search using data from the KAGRA O3GK run
- Author
- Abac A. G.
- Abbott R.
- Abe H.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adamcewicz Christian
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Adya V. B.
- Affeldt C.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi S.
- Alberto Trani Alessandro
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Amra C.
- Anand S.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
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- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés-Carcasona Marc
- Anglin J.
- Anne Bizouard Marie
- Ansoldi S.
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- Antier Sarah
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- de rossi camilla
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- Gamboa Aldo
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- Huddart A. D.
- Hughey B.
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- Hui Victor
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- Huynh-Dinh T.
- Iandolo G. A.
- Iess Alberto
- In Kim Sang
- Inayoshi Kohei
- Inoue Y.
- Iorio Giuliano
- Irwin Jessica
- Isi Maximiliano
- Itoh Yousuke
- Iwaya M.
- Jaberian Hamedan Vahid
- Jacquet Pierre-Edouard
- Jadhav S. J.
- Jadhav Shreejit
- Jain T.
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- Jani Karan
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- Jaraba Santiago
- Jaranowski Piotr
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- Jaume Amengual Rafel
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- KAGRA Collaboration
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- Zucker M. E.
- Zweizig John
- Árpád Gergely László
- 劉 國欽
- 曹周键
- 都丸 隆行
- Publication venue
- Publication date
- 01/03/2024
- Field of study
Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM
Observation of gravitational waves from the coalescence of a 2.5−4.5 M⊙ compact object and a neutron star
- Author
- Abac Adrian
- Abbott R.
- Abouelfettouh I.
- Acernese F.
- Ackley Kendall
- Adhicary S.
- Adhikari Naresh
- Adhikari Rana X.
- Adkins V. K.
- Afif Ismail M.
- Agarwal Deepali
- Agathos Michalis
- Aghaei Abchouyeh Maryam
- Aguiar Odylio D.
- Aguilar I.
- Aiello Lorenzo
- Ain Anirban
- Ajith Parameswaran
- Akcay Sarp
- Akseli Hannuksela Otto
- Akutsu Tomotada
- Al-Jodah Ammar
- Al-Shammari S.
- Albanesi Simone
- Alex iandolo Guido
- Alfaidi Reem Atallah E
- Allocca Annalisa
- Alléné C.
- Altin Paul
- Alvarez-Lopez Sofia
- Amato Alex
- Amez-Droz L.
- Amorosi A.
- Amra C.
- Ananyeva A.
- Anderson Stuart
- Anderson Warren G.
- Andia Manuel
- Ando M.
- Andrade T.
- Andrea Prodi Giovanni
- Andres Nicolas
- Andric Tomislav
- Andrés Vallejo Peña Sergio
- Andrés-Carcasona Marc
- Anglin J.
- Anne Bizouard Marie
- Ansoldi Stefano
- Antelis Javier M.
- Antier Sarah
- Antoni Ramis Vidal Felip
- Antonietta Palaia Maria
- Antonio Font Roda Jose
- Aoumi M.
- Appavuravther E. Z.
- Appert S.
- Apple S. K.
- Arai Koji
- Araya Akito
- Araya Melody
- Areeda Joseph
- Argianas L.
- Arif Shaikh Md
- Aritomi N.
- Armato Federico
- Arnaud Nicolas
- Arogeti Megan
- Aronson Scott
- Arun K. G.
- Ashton Gregory
- Aso Yoichi
- Assiduo M.
- Aston S. M.
- Astone Pia
- Attadio Francesca
- Aubin Florian
- AVALLONE Guerino
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- Yamazaki Ryo
- Yan S.
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- Yang Yi
- Yarbrough Zach
- Yasui H.
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- Yelikar A. B.
- Yin X.
- Yokoyama Jun'ichi
- Yokozawa T.
- Yoo Jooheon
- Yu Hang
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- Zhao Yuhang
- Zheng Yanyan
- Zhong Haowen
- Zhou R.
- Zhu Xingjiang
- Zhu Zong-Hong
- Zimmerman Aaron
- Zucker M. E.
- Zweizig John
- Árpád Gergely László
- 劉 國欽
- 都丸 隆行
- Publication venue
- Publication date
- 23/04/2024
- Field of study
Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial
- Author
- Abab Julie
- Abbas Ali
- Abbassi Sara
- Abd Alazeez Mohamed
- Abdulwahid Danya
- Abdulwahid Danya
- Abed Jessy
- Adab Fawzi
- Adams Marion
- Adamson Vanessa
- Addison Anglise
- Adeyoju Adebanji
- Adinkra Victoria
- Adnaan Jamila
- Afzal Naveed
- Agdiran Didem
- Aggarwal Ajay
- Ahamadali Sheefa
- Ahmad Belal
- Ahmed Ilyas
- Ahmed Imtiaz
- Ahmed Shahida
- Aiku Abimbola
- Ainsworth Sarah
- Ainsworth Sarah
- Aitken Katherine
- Ajzensztejn Daniel
- Akhtar Naeem
- Al-Chamali Hiba
- Al-hasso Abdulla
- Al-hasso Abdulla
- Al-Samarraie Amir
- Albrecht Virginia
- Alcock Christopher
- Alder Leanne
- Alderton Kate
- Aldous Mary
- Ali Jennyfa
- Ali Maryam
- Ali Zulfiqer
- Ali Zulfiqer
- Allan Elaine
- Allan Elaine
- Allen Julie
- Allen Kirsten
- Allen Rachael
- Allen Susan
- Allison Joanna
- Allison Michele
- Alonzi Roberto
- AlRashdan Abdulla
- Alzouebi Mymoona
- Amanie John Oliver
- Ammeter Barb
- Amoaten Thomas
- Amos Claire
- Anderson Beverley
- Anderson Chris
- Anderson Jim
- Anderson John
- Anderson John
- Anderson Juliette
- Anderson Juliette
- Anderson Leanne
- Anderson Naomi
- Anderson Susan
- Anderson Susan
- Andrade Gerard
- Andrews (nee Moore) Eleanor
- Andrews Kelly
- Andrews Stephen
- Ang Daniel
- Ann Taehee
- Annan Lynda
- Ansari Jawaher
- Ansari Jawaher
- Anscombe Eleanor
- Anyamene Nicola
- Appleby Bonny
- Appleby Rowan
- Archer Denise
- Archer Denise
- Archer Simon
- Archer Simon
- Arnott Seonaid
- Arsanious Nasr
- Ashcroft Jan
- Ashworth Sue
- Ashworth Sue
- Askew Sarah
- Aslam Natasha
- Atkinson Jane
- Atkinson Lorraine
- Attlee Julie
- Auladin Raidah
- Austin (nee Glover) Gemma
- Austin Mandy
- Avery Alison
- Avis Joanne
- Aya Viviana
- Azirar Hanna
- Bachand Francois
- Bahary JeanPaul
- Bahl Amit
- Bahl Amit
- Bailey Laura
- Bailey Linda
- Baines Kizzy
- Baird Noelle
- Bak Dagmara
- Bakawala Rehana
- Baker Erin
- Baker Ivanna
- Bakija Zeljka
- Bakker Piet
- Balderson Jane
- Ball Julie
- Balogun Shaki
- Bamford Linda
- Banda Laillah-Crystal
- Barber Dave
- Baria Karin
- Barkati Maroie
- Barkati Maroie
- Barke Nyssa
- Barlow David
- Barnbrooke Sarah
- Barnes Alison
- Barnes Nicky
- Barnett Christian
- Barnett Debra
- Barron Chris
- Barron Claire
- Barter Elisa
- Barwell Lorraine
- Bashir Bashir
- Bashir Faheem
- Basu Devy
- Bateman Samantha
- Bates Emma
- Batish Cheryl
- Batz Margaret
- Bauman Glenn
- Baumber Shelley
- Baxter Matt
- Bayley Andrew J
- Beamish Neal
- Beaney Katherine
- Beaney Ronald
- Beard Karen
- Beard Karen
- Beaton Heather
- Beaton Kirsty
- Beattie Louise
- Beauchemin MarieClaude
- Beaumont Erica
- Beausoleil Rachelle
- Beazer Sarah
- Bech-Nielsen Nanette
- Bech-Nielsen Nanette
- Bedoya Luis Diaz de
- Beech Darren
- Beer Nigel
- Beesley Kate
- Beesley Katherine
- Beesley Sharon
- Beety Jane
- Bekulart Sylwia
- Belcher Rebecca
- Bell Karen
- Bellenger Katharine
- Benjaminson Patricia
- Bennett Molly
- Bennett Sarah
- Bennion Carole
- Benson Richard
- Benson Richard
- Benth Silvine
- Benton Louise
- Benton Richard
- Bentzen Lise
- Beresford Mark
- Beresford Mark
- Beresford Mark
- Bergen Leah
- Berghout Koralee
- Berlin Alejandro
- Bermingham Nicola
- Betts Chris
- Bhana Rajanee
- Bhatnagar Adityanarayan
- Bhatnagar Gagan
- Bici Julia
- Bier Bianca
- Binks Colin
- Binns Louise
- Birch Richard
- Bird Stephanie
- Birtle Alison
- Bishop Emma
- Bissa Caterina
- Bissett Donald
- Bisson MarieEve
- Blackwood Geoffrey
- Blaney Hilary
- Blight Kathy
- Blood Paul A
- Bloomfield David
- Bloomfield David
- Bloomfield Mark
- Blundell Martyn
- Blythe Tracy
- Boam Samantha
- Boardman John
- Bohra Vikram
- Bois (nee Harris) Elizabeth
- Bolger Annette
- Bolton Olivia
- Bolton Olivia
- Bond Brittany
- Bone Linzi
- Bonner Scott
- Bonner-Shand Shelagh
- Bonsu Nicole
- Boon Ian
- Borgaonkar Sudhir
- Borre Michael
- Borynec Carol
- Bott Trevor
- Bottomley David
- Bottomley David
- Bottomley David M.
- Bottomley Ian
- Bouchard Myriam
- Bourke Amie
- Bourque JeanMarc
- Boutflower Jane
- Bowen Jo
- Bowen Jo
- Bowen Katie
- Bower Lorna
- Bower Lorna C.
- Bowers Dawn
- Bowers Richard
- Bowes-Cavanagh Jeanette
- Bowling Lorna
- Bowman Sue
- Bowmer Amanda
- Bownie-Mukumbu Godfrey
- Brady Joanne
- Brady Joanne
- Brain Carol
- Branagan Jennifer
- Branagan Jenny
- Brander Mike
- Branson (née Dineen) Amy
- Brasso Klaus
- Braun Michael W
- Brawley Chris
- Breakspear Sally
- Breckin Edmund
- Breen Vivienne
- Brennan Maria
- Brewster Simon
- Briand Wayne
- Briggs Maxine
- Bristow Robert
- Brittain Paul
- Broadley Eve
- Brock Sue
- Brock Sue
- Brogan (nee Roddie) Stephanie
- Brookes Claire
- Brookman Catherine
- Broom Jane
- Broomfield Barbara
- Brough Richard
- Brough Richard
- Brough WA
- Brown Emmanuel
- Brown Grace
- Brown Joanne
- Brown Maggie
- Brown Rebecca
- Brown Richard B
- Brown Richard B
- Brown Sandra
- Brown Simon
- Brown Stephen CW
- Brown Teddy
- Brownless Caroline
- BrucePayne Kim
- Brulinski Patryk
- Brulinski Patryk
- Brundage Michael
- Bryan Rachel
- Bryant Hanna
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- Bucci Catherine
- Buchan Jonathan
- Buckley Jon
- Buckley Julie
- Bujold Rachel
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- Burlace Barbara
- Burlace Barbara
- Burns Rebecca
- Burrage Su
- Bursey Kara
- Butler-Barnes Jenny
- Butt Zainab
- Butterfield Anne
- Butterworth Caryl
- Buus Simon
- Byrne Mary Marg
- Caballes Mark
- Cadiz Lovely
- Callam Sara
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- Camburn Sister Tracey
- Camilleri Philip
- Camilleri Philip
- Camilleri Philip
- Camilleri Philip
- Campbell Allister
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- Campbell Yvonne
- Campos Monica
- Canavan Joycelin
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- Capaldi Lisa
- Capaldi Lisa
- Capaldi Lisa
- Carbonaro Adriana
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- Carpenter Janice
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- Carter Adam
- Carter Vanda
- Cartwright Debbie
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- Casanova Nathalie
- Casanova Nathalie
- Casey Linda
- Casey Sue
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- Catton Charles
- Catton Charles N.
- Caumont Tom
- Cavanagh Kerrie
- Chadwick David
- Chadwick Eliot
- Chahal Rohit
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- Chakraborti Prabir
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- Challipalli Amarnath
- Chamberlain Shelley
- Chambers Carla
- Chan Andrew
- Chan Andrew
- Chan Heidi
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- Chan Olivia
- Chandrashekara Madhura
- Charnley Natalie
- Chatelain AnneMarie
- Chatfield Jenny
- Chauhan Zainab
- Chedham Alison
- Chennattukungu Indukala
- Cherepak Kathy
- Chetiyawardana Samantha
- Chetiyawardana Samantha
- Chettle Judith
- Cheung Arthur
- Cheung Patrick CF
- Chikkamuniyappa Bindu
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- Chikopela Loveness
- Chilcott Helen
- Chipman Penny
- Chivers Rachael
- Chornopyski Tracy
- Choudhury Ananya
- Choudhury Ananya
- Choudhury Ananya
- Chowdhury Amitava D
- Christensen Anne Juel
- Christensen Tine
- Christmas Sallyanne
- Chrystal Melanie
- Chu William
- Chui Amadeus
- Chung Christina
- Chung Hans T
- Chung Peter
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- Churn Mark
- Churn Mark
- Clancy Joanna
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- Clark Alison
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- Clarke Jude
- Clarke Maria
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- Clarke Noel W.
- Clarke Peter
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- Clarke Samantha
- Cleary Kristy
- Clements Colette
- Clements Mia AnnaMaria
- Clitheroe Pat
- Cobos-Arrivabene Marta
- Cocks Tracie
- Coe Marc
- Coffin Teresa
- Cogley Lyn
- Cogley Lyn
- Cole Aiden
- Cole David J
- Cole David J
- Collard Susan
- Colligan Steve
- Collins Gerald
- Collins Gerald
- Collins Lucy
- Commisso Angela
- Conibear John
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- Connor Marie
- Conroy Ruth
- Conroy Ruth
- Conway Lisa-Jane
- Conway Rachel
- Cook Adrian
- Cook Adrian D.
- Cook Audrey
- Cook Audrey
- Cook Wendy
- Cooke Jill
- Cooke Juniebel
- Cooke Peter
- Coomber Kristy
- Coombs Sarah
- Cooper Adele
- Cooper Sophie
- Coppins Helen
- Corbett Thomas B
- Corcoran Sam
- Corderoy Helen
- Cordwell Amanda
- Corkery Danylle
- Corless Rebecca
- Cormack Margaret
- Cornaby Andrew
- Corner Victoria
- Cornthwaite Stephanie
- Corwin Charlotte
- Cossette Danielle
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- Coubrough Claudia
- Couch Ellie
- Coughlan Tricia
- Cousins Jane
- Cousins Rebecca
- Coutts Tim
- Coventry Thomas
- Cowan Chloe
- Cowan Chloe
- Cowan Richard
- Cowan Richard
- Cowley Sue
- Cox Adam
- Cox Christine
- Coyle Catherine
- Coyle Catherine
- Crawford Melanie
- Crawford Sister Denise
- Creelman Brianna
- Crellin Perric
- Crellin Perric
- Crook Juanita
- Cross Vanessa
- Cross William R.
- Crossley Lin
- Crowe (nee Hughes) Dawn
- Crowley Claire
- Crundwell M
- Cserbane Anita
- Cuffe Donna
- Cumming Kirsty
- Cunningham Amy
- Curtis Samantha
- Curtis Sandra
- Cusan Leonello
- Custins Laura
- Cyriac Abby
- Dabbs Marianne
- Dahar Nazeer
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- Dallas Nicola
- Dalton-Short Ross
- Dalton-Short Ross
- Daly Deirdre
- Danaswamy Patricia
- Danaswamy Patricia
- Daniel Amelia
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- Darby Helen
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- Davidson Cathy
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- Davies Flor
- Davies Heather
- Davies Joe
- Davies Joseph
- Davies Julie-Ann
- Davies Kirstin
- Davies Llinos
- Davies Stacey
- Davies Sue
- Davies Tracey
- Davison Alison
- Davison Sue
- Dawe David
- Dawson Elizabeth
- Dawson Louise
- Dawson-Athey Linda
- Dayes Ian S
- De Silva-Minor Shiroma
- Dean Lynsey
- Dearnaley David
- Deenihan Emma
- Degendorfer Sarah
- Dekaj Fatjon
- Dell Gillian
- Dellar Conor
- Delouya Guila
- Dent Kathleen
- Desai Parth
- Desai Parth
- Desrosiers Isabelle
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- Di Maria Fabio
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- Din Omar
- Ding Ian
- Dion Helene
- Ditchfield Julie
- Dixit Sanjay
- Dixit Sanjay
- Dlodlo Jessica
- Dobson Tracey
- Dodds David
- Dodge Sister Jan
- Doherty A
- Donaghey Sally
- Donaldson David
- Donnison Michelle
- Douch Emma
- Doughty Victoria
- Dover Serena
- Downs Nichola
- Doyle Kerrie
- Drachenberg Darrel E
- Drakeley Susan
- Drew Ellen
- Drew Mary (Ellen)
- Driscoll Celine
- DSouza David
- Dubey Arbind
- Dubey Arbind
- Duckett Tracey
- Duclos Marie
- Duffy Annie
- Dufour Nathalie
- Dugas Stevie
- Duley Emma
- DuMontier Joelle
- Duncan (nee Keatley) Claire
- Duncan Graeme
- Duncan Ian
- Dunn Sharon
- Dunne Emma
- Durkan Garret
- Durrant Lisa
- Dymond Harvey
- E Choan
- Eady Robin
- Eapen Libni
- Ebacher Annie
- Eccleson Helen
- Edwards Abigail
- Edwards Albert
- Edwards Jackie
- Edwards Steve
- Edwards Steve
- Egan Lisa
- Eichenberger Lois
- El-Modir Ahmed
- El-Saghir Mohammed
- Eleftheriadis Symeon
- ElKerdawy Hala
- Ellard Rose
- Elliott Mark
- Elliott Tony
- Elliott Tony
- ElSokhn Nidale
- Elwell Christine
- Elwell Christine
- Elwell Sue
- Embleton Andrew
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- Erskine Susan
- Escueta Vivette
- Eska Tiffani
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- Evans Richard
- Eze Nancy
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- Falconer Alison
- Fallah Fereshteh
- Fallaize Adrian
- Faria Sergio Luiz
- Farnworth Christine
- Farrar Michelle
- Farrell Helen
- Fawcitt Sara
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- Fearnley Mark
- Featherstone Wendy
- Fellows Kathryn
- Fennelly Ruth
- Ferguson Catherine
- Ferguson Catherine
- Fernandez Claire
- Ferreira Miguel
- Fiddes Kathleen
- Fielding Bethany
- Fielding Bethany
- Fildes Diane
- Finnegan Niall
- Firth Alexandra
- Firth Alexandra
- Firth Alexandra
- Firth Elizabeth
- Fish Matt
- Fish Nathan
- Flaherty Jan
- Flaherty Jan
- Flanagan Laura
- Flavin Aileen
- Fletcher Joanne
- Fletcher Julie
- Fletcher Mandy
- Flynn-Batham Marian
- Fode Kirsten
- Folkes Linda
- Follows Josh
- Foo Maxine
- Foot Jayne
- Forcat Silvia
- Forcat Silvia
- Ford Amanda
- Ford Amy
- Ford Chris
- Ford Daniel
- Ford Daniel
- Ford Nicky
- Ford Victoria
- Ford Victoria
- Forkes Janet
- Forkes Janet
- Forkes Janet
- Forman Susan
- Forrest Diane
- Forrest Diane
- Fortin Jacqueline
- Fosker Chris
- Fossey Gavin
- Foster Emma
- Foster William
- Fourt Monica
- Fox Shirley
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- Francis Olesya
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- Frankland Helen
- Franklin Alex
- Frattaroli Paul
- Frazzi Alexandra
- Frew John
- Frim Olivera
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- Gamble Tina
- Gamble Tina
- Gamez Raquel
- Ganabady Malavika
- Gao Annie
- Garcia Leni Santiago
- Gardiner Fiona
- Garner Victoria
- Garrett Gina
- Garrido-Perez Sandra
- Gauntlett Monica
- Gauthier Isabelle C
- Gearing Jennifer
- George Siny
- GeorgeChayka Danielle
- Geraghty Kerry
- Ghoul Mokhtar
- Gibbins Andrew
- Gibbins Jackie
- Gibbins Kate
- Gibbs Stephanie
- Gibson Sian
- Giddings Emma
- Gilbert Duncan
- Gilbert Duncan
- Gilbert Jeanette
- Gilby Lisa
- Gilchrist Gail
- Gill Lisa
- Gill Shafiq
- Gillatt David
- Gillatt David
- Gillesen Annelies
- Gillespie Sally
- Gillian Andrew
- Gilmartin Claire
- Gilmour Christina
- Ginnelly Helen
- Ginnelly Helen
- Giovannini Julia
- Gipson Anna
- Girolametto Carla
- Gladwell Louise
- Gladwish Adam
- Glaholm John
- Glaholm John
- Gleave Martin E
- Glen Hilary
- Glen Tracy
- Glick Daniel
- Goel Roshni
- Goh Chee
- Goh Chee L.
- Golden Sophie
- Goldenberg S Larry
- Goldstein Cindy
- Goldstein Cindy
- Goldsworthy Simon
- Gollapothu Srilakshmi
- Gomez JoseLuis
- Gomez-Marcos Raquel
- Gonzalez Celia
- Gooch Carol
- Goodhind Frances
- Goodsell Josie
- Goodsell Josie
- Goodwin Emma
- Gopaul Darindra
- Gordon Hussain
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- Goss Vanessa
- Gough Jessica
- Gould Aaron
- Goulden Kay
- Goulding James
- Goyena Ruby
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- Graham Jeffrey
- Graham John
- Graham Susan
- Gramlich Colin
- Grant Anna
- Grant Cordelia
- Grant Judith
- Grant Susan
- Grant Warren
- Gratton Albert
- Grau Isabel
- Gray Emma
- Gray Emma
- Grayland Sarah
- Greedus Helen
- Green James
- Green Sara
- Green Sarah
- Green Sue
- Green Trish
- Greenland Jonathan
- Gregg Jane
- Gregorcic Emily
- Gregory Debbie
- Grieve Sylvia
- Griffen Ailsa
- Griffin Hannah
- Griffiths Dorothy
- Griffiths Leyshon
- Griffiths Theresa
- Griffiths Theresa
- Gruschy Lisa
- Guarino Robyn
- Gudelis Susan O
- Guerrero-Urbano Teresa
- Guerrero-Urbano Teresa
- Guerrero-Urbano Teresa
- Gujral Sandeep
- Gumapac Nicole
- Gunn Melanie
- Gupta Kamalnayan
- Gupta Nishi
- Gurzanski Christina
- Guy Peter
- Gwilt Julie
- Gwilt Julie
- Gwilt Julie
- Haddad Alain
- Hagan Chris
- Hague Dominic
- Haidar Imran
- Haidar Imran
- Haigh Steve
- Haldeos Anne
- Hale Jennifer
- Hall Jane
- Hall Julia
- Hall Julia
- Halperin Ross
- Hamid Abdel
- Hamill Maureen
- Hamilton Beatrice
- Hamilton Joanna
- Hamilton Ronald
- Hammonds John Christopher
- Hanna Emma
- Hannaford Zeta
- Happle Liz
- Hardie Maryon
- Harding Claudia
- Harding Joshua
- Hardman John
- Hardstaff Lisa
- Hare Jennifer A
- Hargreaves Carolyn
- Hargreaves Jeanette
- Hargreaves Jeanette
- Harinarayanan Sathish
- Harinarayanan Sathish
- Harland Keith
- Harney Jackie
- Harnwell Juliette
- Harpell Rhonda
- Harris (n. Marchant) Emily
- Harris Catherine
- Harris Sarah
- Harris-Burland Angie
- Harrison Alison
- Harrow Sister Kath
- Hart Amber
- Hart Andrew
- Harter Leah
- Hartley Jasmine
- Hartman Carrie
- Hartt Nancy
- Hartwell Lyn
- Harvey Julie
- Harvey Sally
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- Haskell Annelise
- Hassall Alison
- Hassan Nebah
- Hassan Nebah
- Hathout Lara
- Hatimy Umi
- Haydock Helen
- Haydock Helen
- Hayes Jill A
- Hayward Lesley
- Healey Gail
- Healey-Mariano Jennifer
- Healey-Mariano Jennifer
- Heasley Karen
- Heath Catherine
- Heckford Louise
- Hedges Andy
- Heeley Janine
- Hefferon Billy
- Hegarty Gemma
- Hejlesen Finn
- Helou Joelle
- Hendel Debra
- Henry Ann
- Henry Ann
- Henry Ann
- Henry Ann
- Henry Joanne
- Henry Joanne
- Henson (nee Savidge) Verity
- Henson Helen
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- Herbert Chris
- Herbert Gaynor
- Heron Jane
- Hetherington Stacey
- Hicks Kimberly
- Higgins Linda
- Hijab Adham
- Hill Elaine
- Hill Judy
- Hill Pipa
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- Hillman Paul
- Hillman Paul
- Hilman Serena
- Hilman Serena
- Hindle Margaret
- Hines John
- Hoare Kathryn
- Hocking Christopher
- Hodder June
- Hodge Simon
- Hodges Samantha
- Hodgkinson Sheila
- Hodson Hayley
- Hodson Hayley
- Hogan Holly
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- Hogbin Emma
- Hogbin Emma
- Holbrook Andy
- Holbrook Becky
- Holden Simon
- Holdsworth Amanda
- Hollenhorst Helmut
- Holliday Samantha
- Hollingdale Abigail
- Hollis Keri
- Hollister Robert
- Holloway Caroline
- Holmes Evelyn
- Holwerda Eleanor
- Homer David
- Hood Marion
- Hooper Simon
- Hooton Georgia
- Hore Brendan
- Horne Rhian
- Hornzee Gillian
- Hornzee Gillian
- Horton Sarah
- Horwich Alan
- Hoskin Peter
- Hoskin Peter
- Hoskins Ashley
- Hoskins Chloe
- Hotine Jodie
- Hough Adele
- Hough Chris
- Houghton Fionnuala
- Houle Stefanie
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- Howard Joanna
- Howard Lucy
- Howard Lucy
- Howitt Pamela
- Hsien John
- Hubley Lynn
- Huddart Robert
- Huddart Robert
- Hudson Zoe
- Hughes Claire
- Hughes Faye
- Hughes Hayley
- Hughes Joanne
- Hughes Kathryn
- Hughes Owen
- Hughes Robert
- Hughes Simon
- Hughes-Davies Luke
- Hugill Angela
- Hugill Angela
- Humber Caroline
- Humpreys Louise
- Hunt Allison
- Hunter Catherine
- Hunter William
- Hunting Liz
- Hutchinson Camille
- Hyde Katherine
- Hyde Katherine
- Hyde Katherine
- Hynds Sharon
- Ibrahim Azman
- Ingham Jo
- Ingle Charlotte
- Inman Hayley
- Innes Helen
- Iordanidi Elina
- Iqbal Fawaad
- Irwin P
- Isaew Andrea
- Iskender Amanda
- Islam Zaheer
- Issa Rami
- Ivie Stephanie
- Jackman Dee
- Jackson Cathy
- Jackson Kim
- Jackson Sister Ann
- Jain Suneil
- Jakeman Christine
- James Naomi
- James Nicholas
- Jamieson Ceri
- Jampana Raj
- Janke Susan
- Jannapureddy Revanth
- Jarvis Claire
- Jastrzebska Patrycja
- Javle P
- Jayachandran Resmi
- Jayachandran Resmi
- Jeffcutt Nicole
- Jeffrey David
- Jelski Joseph
- Jenkins Peter
- Jenkins Suzanne
- Jenner Abigail
- Jennings Marian
- Jepson Debbie
- Jevons Cody
- Jewers Karen
- Jewers Karen
- Jeyasanger Ganesan
- Joe Howard
- John Babbin
- Johns Louise
- Johnson Arlissa
- Johnson Craig
- Johnson Joanne
- Johnson Lyndsey
- Johnson Nigel
- Johnson-Rollings Ashley
- Johnston Laurel
- Johnston Ruth
- Johnstone Dawn
- Johnstone Maria
- Joncas MarieClaude
- Jones (Birch) Janine
- Jones Andrea
- Jones Ania
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- Jones Cathryn
- Jones Clare
- Jones Dawn
- Jones Gareth
- Jones Ifan
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- Jones Julia
- Jones Kathryn
- Jones Katie
- Jones Lesley
- Jones Lewis
- Jones Richard
- Jones Rob
- Jones Stephanie
- Jones Stephanie
- Jones-Skipper Kay
- Jonnada Sai
- Jope Carmel
- Jose Sanal
- Joseph Joji
- Joseph Paul K
- Joshi Manisha
- Joshi Manisha
- Joslin Vicky
- Jovic Gordana
- Kaa Bach Birgit
- Kader Nicole
- Kalejaiye Odunayo
- Kaliski Alexandre
- Kalyvas Maria
- Kamran Asim
- Kanaga-Sundaram Subramanian
- Kancherla Kiran
- Kanji Femina
- Kanyi Karen
- Kapur Guarav
- Karim Omer
- Karp Stephen
- Karsera Louise
- Karunakaran Subashini
- Karvat Anand
- Kaushal Malan
- Kavanagh Roisin
- Kavanagh Roisin
- Kay Anne Marie
- Kazingizi Memory
- Keane Patrick
- Kearney S
- Kedge Liz
- Kehoe Laura
- Keith Sarah
- Keith Sarah
- Kelkar Anand
- Kellaway Joanne
- Kelly Alison
- Kelly Kay
- Kemp Gail
- Kempel Mette Moe
- Kendal Wayne S
- Keng-Koh Pek
- Keng-Koh Pek
- Keni Manjusha
- Kennedy Julie
- Kenny Shannon
- Kent Christopher
- Kent Emma
- Kenyon Lucille
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- Key Claire
- Keyes Mira
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- Khong Rachel
- Khoo Vincent
- Khoo Vincent
- Khoo Vincent
- Khoury Ghassan
- Kiff Janet
- Kift Shannon
- Kilmartin John
- Kilroy Stephen
- Kilroy Stephen
- Kiltie Anne
- Kiltie Anne
- Kim David
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- KimSing Charmaine
- King Amy
- King Jennifer
- King Jennifer
- King Lisa
- Kinrade Yvonne
- KirbyBello Denise
- Kirk Christine
- Kirk Sister Sarah
- Kirkbride Peter
- Kirkbride Peter
- Kirkby Amy
- Kirkby Sarah
- Kirkpatrick Suriya
- Kisanga Mary
- Kitkowski Caitlin
- Klapp Kathi
- Klotz Laurence
- Klovgaard Karina
- Knackstedt Jochen
- Knapp Jeanette
- Knight (n. Sherburn) Victoria
- Knott Helen
- Knox WF
- Kockelbergh Roger
- Koehler Ingrid
- Kokholm Kathrine Friser
- Koll Wayne
- Kong Vickie
- Kotze Michelle
- Koul Rashmi
- Koulouris Zoe
- Koupparis Anthony
- Kowalczyk-Williams Wioletta
- Kowalewska Paulina
- Kronstal Flo
- Krysta Beata
- Kuenzig Greg
- Kujawa Magda
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- Kumar Daniel
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- Kumar Shiyam
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- Kurup Rahul
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- Kwan Winkle
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- Kynaston Howard
- Kynaston Howard
- Lacey Cathy
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- Lactao Ranee
- Ladouceur Cynthia
- Laing Robert
- Lajoie MarieAndree
- Lake Sister Judith
- Lalani Nafisha
- Laliberte Benoit
- Lam Jacqueline
- Lambert Carole
- Lambert Katy
- Lamoureux Alexandra
- Lang Monika
- Langridge Nicole
- Laniado M
- Lao Bernadeth
- Larkins Rachel
- Larocque Stephanie
- Larouche Julie
- Larson Beverly
- Lassen Yasmin
- Last Debbie
- Lau Maurice
- Laubscher Angelique
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- Laursen Vibeke
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- Laverick Rosaleen
- Lavertu Sophie
- Lawless Claire
- Lawless Theresa
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- Lawrence Steph
- Lawrey Sarah
- Lawson Daeria
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- Leach Deborah
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- Leong Nelson
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- Lewington Val
- Lewis Amanda
- Lewis Christina
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- Li Audrey
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- Lim Jan
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- Lipsham Margaret
- Liptrott Sarah
- Lister Debbie
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- Little Erin
- Little Jessica
- Littler John
- Littler Stephen
- Liu Stanley
- Livsey Jacqueline
- Livsey Jacqueline
- Lloyd-Jones Hugh
- Loblaw Douglas Andrew
- Lock Michael I
- Locke Angela
- Lockwood Carol
- Logue John
- Logue John
- Logue John
- Logue John
- Lokes Rachel
- Lokes Rachel
- Lomas Alia
- Lomas Claire
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- Loughlin Kate
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- Love Sally
- Lowe Amelia
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- Lucakova Slavka
- Lukka Himu
- Lunau Anne Sofie
- Lydon Anna
- Lydon Anne Marie
- Lynch Rory
- Lyons Ciara
- Mabelin Louies
- Macavoy Tina
- Macdonald Alison
- MacDonald Angela
- MacDonald Graham
- Macefield Rhiannon
- MacGregor Barbara
- Macgregor Carol
- MacIsaac Kathy
- MacIsaac Patricia
- Mackay Rachel
- Macleod Nicholas
- MacMillan Antonia
- MacMullin Lisa
- MacRae Robert M
- Macrory Joanne
- MacVicar Jennifer
- MacVicar Karen
- Madeleine Jude
- Madhava Kudingila
- Madine John
- Magwaro Sophia
- Magwaro Sophia
- Magwaro Sophia
- Mahmood Rana
- Mahmood Rana
- Mahmood Sana
- Mahmud Aamer
- Mahoney Catriona
- Mahoney Sue
- Maitland Katrina
- Maize Christine
- Majumdar Arpita
- Makepeace Barbara
- Malde Rohit
- Malek Leila
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- Mallett Debbie
- Malone Shawn
- Malone Shawn C.
- Manetta Caroline
- Manganaro Aileen
- Mangar Stephen
- Maniatis Christos
- Manley Rachel
- Mannan Aliyah
- Manning Courtney
- Manning Kimberley
- Mansell Gemma
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- Mantle Mark
- Manyangadze Sarah
- Marange Josephine
- Mardell Stephen
- Marek Kathleen
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- Marineau Line
- Mark Ian
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- Marquis Tania
- Marriott Sue
- Marshall John
- Marshall Lynn
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- Marston Kerrie
- Martin AndreGuy
- Martin Jackie
- Martin Joseph
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- Martindale John
- Martindale John
- Martindale John
- Martinez Maria
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- Marty Janet
- Mashegede Beverley
- Mason Jessica
- Mason Malcolm
- Masson Susan
- Masson Susan
- Masters Benjamin
- Masters Lindsey
- Masters Lindsey
- Matkins Ellen
- Matthews Laura
- Mattocks Lehentha
- Mayer Heather
- Mayne Barbara
- Mazhar Danish
- McAleese Jonathan
- McAlister Judy
- McAllister Jo
- McAuliffe Sarah
- McBain Hazel
- McBride Julia
- McCabe Alastair
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- Wassall Rebecca
- Watkinson Catrin
- Watson Melanie R
- Watson Michaella
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- Wong Jason W T
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- Worlding Jane
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- Worthington Hannah
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- Wronski Sue
- Wu Helen
- Wu Min
- Wyatt Clare
- Wylie James
- Wylie James
- Wylie James
- Wylie James P.
- Wynn Hazel
- Wynn Hazel
- Yanchuk Janet
- Yarrow Sue
- Yassa Michael
- yates Victoria
- Yee Don
- Yeo Tanya
- Yoon Frederick
- Youd Sister Jill
- Young Anita
- Young Bobbie
- Young Douglas
- Young Sally
- Youngs Nora
- Yu Jason
- Yunace Lorrie
- Yusof Hilawati
- Zafar Waheed
- Zaidi Sadaf
- Zarkar Anjali
- Zarkar Anjali
- Zarkar Anjali M.
- Zaza Khaled O
- Zelley Sarah
- Zeltser Fred
- Zhang Hanbo
- Zhang Tina Wanting
- Zietz Maria
- Zilkha Helene
- Zinck Connie
- Zinyemba Vivian
- Zurakovsky Hilary
- Zwarych Darlene
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/06/2024
- Field of study
Background
Previous evidence indicates that adjuvant, short-course androgen deprivation therapy (ADT) improves metastasis-free survival when given with primary radiotherapy for intermediate-risk and high-risk localised prostate cancer. However, the value of ADT with postoperative radiotherapy after radical prostatectomy is unclear.
Methods
RADICALS-HD was an international randomised controlled trial to test the efficacy of ADT used in combination with postoperative radiotherapy for prostate cancer. Key eligibility criteria were indication for radiotherapy after radical prostatectomy for prostate cancer, prostate-specific antigen less than 5 ng/mL, absence of metastatic disease, and written consent. Participants were randomly assigned (1:1) to radiotherapy alone (no ADT) or radiotherapy with 6 months of ADT (short-course ADT), using monthly subcutaneous gonadotropin-releasing hormone analogue injections, daily oral bicalutamide monotherapy 150 mg, or monthly subcutaneous degarelix. Randomisation was done centrally through minimisation with a random element, stratified by Gleason score, positive margins, radiotherapy timing, planned radiotherapy schedule, and planned type of ADT, in a computerised system. The allocated treatment was not masked. The primary outcome measure was metastasis-free survival, defined as distant metastasis arising from prostate cancer or death from any cause. Standard survival analysis methods were used, accounting for randomisation stratification factors. The trial had 80% power with two-sided α of 5% to detect an absolute increase in 10-year metastasis-free survival from 80% to 86% (hazard ratio [HR] 0·67). Analyses followed the intention-to-treat principle. The trial is registered with the ISRCTN registry, ISRCTN40814031, and ClinicalTrials.gov, NCT00541047.
Findings
Between Nov 22, 2007, and June 29, 2015, 1480 patients (median age 66 years [IQR 61–69]) were randomly assigned to receive no ADT (n=737) or short-course ADT (n=743) in addition to postoperative radiotherapy at 121 centres in Canada, Denmark, Ireland, and the UK. With a median follow-up of 9·0 years (IQR 7·1–10·1), metastasis-free survival events were reported for 268 participants (142 in the no ADT group and 126 in the short-course ADT group; HR 0·886 [95% CI 0·688–1·140], p=0·35). 10-year metastasis-free survival was 79·2% (95% CI 75·4–82·5) in the no ADT group and 80·4% (76·6–83·6) in the short-course ADT group. Toxicity of grade 3 or higher was reported for 121 (17%) of 737 participants in the no ADT group and 100 (14%) of 743 in the short-course ADT group (p=0·15), with no treatment-related deaths.
Interpretation
Metastatic disease is uncommon following postoperative bed radiotherapy after radical prostatectomy. Adding 6 months of ADT to this radiotherapy did not improve metastasis-free survival compared with no ADT. These findings do not support the use of short-course ADT with postoperative radiotherapy in this patient population
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