298 research outputs found
Controlled extrinsic magnetoelectric coupling in BaTiO3/Ni nanocomposites: Effect of compaction pressure on interfacial anisotropy
International audienceThe dynamical control of the dielectric response in magnetoelectric (ME) nanocomposites (NCs) renders an entire additional degree of freedom to the functionality of miniaturized magnetoelectronics and spintronics devices. In composite materials, the ME effect is realized by using the concept of product properties. Through the investigation of the microwave properties of a series of BaTiO3/Ni NCs fabricated by compaction of nanopowders, we present experimental evidence that the compaction (uniaxial) pressure in the range 33-230 MPa affects significantly the ME features. The Ni loading was varied from zero (BaTiO3 only) to 63 volâ%. Our findings revealed that the ME coupling coefficient exhibits a large enhancement for specific values of the Ni volume fraction and compaction pressure. The coupling effects in the NCs were studied by looking at the relationships among the crystallite orientation and the magnetic properties. The magnetization curves for different directions of the applied magnetic field cannot be superimposed. We suggest that the average magnetization measurements on these NCs under compressive stress are dominated by strain anisotropy rather than magnetocrystalline anisotropy. Overall, these observations are considered to be evidence of stress-induced microstructural changes under pressure which strongly affect the elastic interaction between the magnetostrictive and piezoelectric phases in these NCs. These results have a potential technological impact for designing precise tunable ME NCs for microwave devices such as tunable phase shifters, resonators, and delay lines
Protein-Peptide Turnover Profiling reveals the order of PTM addition and removal during protein maturation
Post-translational modifications (PTMs) regulate various aspects of protein function, including degradation. Mass spectrometric methods relying on pulsed metabolic labeling are popular to quantify turnover rates on a proteome-wide scale. Such data have traditionally been interpreted in the context of protein proteolytic stability. Here, we combine theoretical kinetic modeling with experimental pulsed stable isotope labeling of amino acids in cell culture (pSILAC) for the study of protein phosphorylation. We demonstrate that metabolic labeling combined with PTM-specific enrichment does not measure effects of PTMs on protein stability. Rather, it reveals the relative order of PTM addition and removal along a protein's lifetime-a fundamentally different metric. This is due to interconversion of the measured proteoform species. Using this framework, we identify temporal phosphorylation sites on cell cycle-specific factors and protein complex assembly intermediates. Our results thus allow tying PTMs to the age of the modified proteins
Node-like excitations in superconducting PbMo6S8 probed by scanning tunneling spectroscopy
We present the first scanning tunneling spectroscopy study on the Chevrel
phase PbMo6S8, an extreme type II superconductor with a coherence length only
slightly larger than in high-Tc cuprates. Tunneling spectra measured on
atomically flat terraces are spatially homogeneous and show well-defined
coherence peaks. The low-energy spectral weight, the zero bias conductance and
the temperature dependence of the gap are incompatible with a conventional
isotropic s-wave interpretation, revealing the presence of low-energy
excitations in the superconducting state. We show that our data are consistent
with the presence of nodes in the superconducting gap.Comment: To appear in PRB; 5 pages, 4 figure
Multi-band Superconductivity in the Chevrel Phases SnMo6S8 and PbMo6S8
Sub-Kelvin scanning tunnelling spectroscopy in the Chevrel Phases SnMo6S8 and
PbMo6S8 reveals two distinct superconducting gaps with Delta_1 = 3 meV, Delta_2
~ 1.0 meV and Delta_1 = 3.1 meV, Delta_2 ~ 1.4 meV respectively. The gap
distribution is strongly anisotropic, with Delta_2 predominantly seen when
scanning across unit-cell steps on the (001) sample surface. The spectra are
well-fitted by an anisotropic two-band BCS s-wave gap function. Our
spectroscopic data are confirmed by electronic heat capacity measurements which
also provide evidence for a twin-gap scenario.Comment: 5 pages, 4 figure
Quantum mechanical description of Stern-Gerlach experiments
The motion of neutral particles with magnetic moments in an inhomogeneous
magnetic field is described in a quantum mechanical framework. The validity of
the semi-classical approximations which are generally used to describe these
phenomena is discussed. Approximate expressions for the evolution operator are
derived and compared to the exact calculations. Focusing and spin-flip
phenomena are predicted. The reliability of Stern-Gerlach experiments to
measure spin projections is assessed in this framework.Comment: 12 pages, 7 eps figures included, revtex, submitted to PR
Antimicrobial resistance, virulence factorsand genetic lineages of hospital-onsetmethicillin-resistant Staphylococcus aureus isolates detected in a hospital in Zaragoza
Introduction
MRSA population dynamics is undergoing significant changes, and for this reason it is important to know which clones are circulating in our nosocomial environment.
Materials and methods
A total of 118 MRSA isolates were collected from clinical samples from patients with previous hospital or healthcare contact (named as hospital-onset MRSA (HO-MRSA)) during a one year period. Susceptibility testing was performed by disk diffusion and microdilution. The presence of resistance genes and virulence factors were tested by PCR. All isolates were typed by SCCmec, spa and agr typing. PFGE and MLST were applied to a selection of them.
Results
Eighty-three HO-MRSA isolates (70.3%) were resistant to any antibiotic included in the macrolideâlincosamideâstreptogramin B group. Among these isolates, the M phenotype was the most frequent (73.5%). One hundred and seven of HO-MRSA isolates (90.7%) showed aminoglycoside resistance. The combination aac(6')-Ie-aph(2")-Ia + ant(4')-Ia genes was the most frequent (22.4%). Tetracycline resistance rates in HO-MRSA isolates were low (3.4%), although a high level of mupirocin resistance was observed (25.4%). Most of the HO-MRSA isolates (approximately 90%) showed SCCmec type IVc and agr type II. Fifteen unrelated pulsotypes were identified. CC5 was the most prevalent (88.1%), followed by CC8 (5.9%), CC22 (2.5%), CC398 (2.5%) and CC1 (0.8%).
Conclusion
CC5/ST125/t067 lineage was the most frequent. This lineage was related to aminoglycoside resistance, and to a lesser extent, with macrolide resistance. The presence of international clones as EMRSA-15 (CC22/ST22), European clones as CC5/ST228, community clones related to CC1 or CC8 and livestock associated clones, as CC398, were observed in a low percentage
Structural effect of heavy ion irradiation on GdBaCuO ceramics
The influence of twin boundaries as sinks on defects induced by 480 keV Kr ion irradiation in GdBaCuO crystals was observed in situ at 40 and 300 K. The interaction of the dislocations with the twin boundaries followed on a video recording. A crystalline to amorphous transition was observed above a total fluence of ⌠4 - 5 x 10^12 Kr/cm2. A comparison between orthorhombic (Os) crystals and a monoclinic structure (Ms) (close to Os and whose parameters were calculated) shows that the behaviour of irradiation-induced extended defects does not depend on a small initial deformation of the orthorhombic cell. In both case, an occasional orthorhombic (or monoclinic) to tetragonal phase transition only occurs when the amorphization process has begun
Comorbidities and Treatment-Limiting Decisions in Older Adults Dying in the Emergency Department: Is There an Association?
International audienc
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