1,145 research outputs found

    Ship-hull shape optimization with a T-spline based BEM-isogeometric solver

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    In this work, we present a ship-hull optimization process combining a T-spline based parametric ship-hull model and an Isogeometric Analysis (IGA) hydrodynamic solver for the calculation of ship wave resistance. The surface representation of the ship-hull instances comprise one cubic T-spline with extraordinary points, ensuring C2 continuity everywhere except for the vicinity of extraordinary points where G1 continuity is achieved. The employed solver for ship wave resistance is based on the Neumann-Kelvin formulation of the problem, where the resulting Boundary Integral Equation is numerically solved using a higher order collocated Boundary Element Method which adopts the IGA concept and the T-spline representation for the ship-hull surface. The hydrodynamic solver along with the ship parametric model are subsequently integrated within an appropriate optimization environment for local and global ship-hull optimizations against the criterion of minimum resistance

    Wave-resistance computation via CFD and IGA-BEM solvers : a comparative study

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    This paper delivers a preliminary comparative study on the computation of wave resistance via a commercial CFD solver (STAR-CCM+®) versus an in-house developed IGA-BEM solver for a pair of hulls, namely the parabolic Wigley hull and the KRISO container ship (KCS). The CFD solver combines a VOF (Volume Of Fluid) free-surface modelling technique with alternative turbulence models, while the IGA-BEM solver adopts an inviscid flow model that combines the Boundary Element approach (BEM) with Isogeometric Analysis (IGA) using T-splines or NURBS. IGA is a novel and expanding concept, introduced by Hughes and his collaborators (Hughes et al, 2005), aiming to intrinsically integrate CAD with Analysis by communicating the CAD model of the geometry (the wetted ship hull in our case) to the solver without any approximation

    Sampling of temporal networks: methods and biases

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    Temporal networks have been increasingly used to model a diversity of systems that evolve in time; for example, human contact structures over which dynamic processes such as epidemics take place. A fundamental aspect of real-life networks is that they are sampled within temporal and spatial frames. Furthermore, one might wish to subsample networks to reduce their size for better visualization or to perform computationally intensive simulations. The sampling method may affect the network structure and thus caution is necessary to generalize results based on samples. In this paper, we study four sampling strategies applied to a variety of real-life temporal networks. We quantify the biases generated by each sampling strategy on a number of relevant statistics such as link activity, temporal paths and epidemic spread. We find that some biases are common in a variety of networks and statistics, but one strategy, uniform sampling of nodes, shows improved performance in most scenarios. Given the particularities of temporal network data and the variety of network structures, we recommend that the choice of sampling methods be problem oriented to minimize the potential biases for the specific research questions on hand. Our results help researchers to better design network data collection protocols and to understand the limitations of sampled temporal network data

    Identification of Giardia lamblia DHHC Proteins and the Role of Protein S-palmitoylation in the Encystation Process

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    Protein S-palmitoylation, a hydrophobic post-translational modification, is performed by protein acyltransferases that have a common DHHC Cys-rich domain (DHHC proteins), and provides a regulatory switch for protein membrane association. In this work, we analyzed the presence of DHHC proteins in the protozoa parasite Giardia lamblia and the function of the reversible S-palmitoylation of proteins during parasite differentiation into cyst. Two specific events were observed: encysting cells displayed a larger amount of palmitoylated proteins, and parasites treated with palmitoylation inhibitors produced a reduced number of mature cysts. With bioinformatics tools, we found nine DHHC proteins, potential protein acyltransferases, in the Giardia proteome. These proteins displayed a conserved structure when compared to different organisms and are distributed in different monophyletic clades. Although all Giardia DHHC proteins were found to be present in trophozoites and encysting cells, these proteins showed a different intracellular localization in trophozoites and seemed to be differently involved in the encystation process when they were overexpressed. dhhc transgenic parasites showed a different pattern of cyst wall protein expression and yielded different amounts of mature cysts when they were induced to encyst. Our findings disclosed some important issues regarding the role of DHHC proteins and palmitoylation during Giardia encystation.Fil: Merino, Maria Cecilia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Zamponi, Nahuel. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Vranych, Cecilia Verónica. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Touz, Maria Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; ArgentinaFil: Ropolo, Andrea Silvana. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra. Universidad Nacional de Córdoba. Instituto de Investigación Médica Mercedes y Martín Ferreyra; Argentin

    Sustainable transport modes, travel satisfaction, and emotions: Evidence from car-dependent compact cities

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    This study investigates how the use of sustainable transport modes relates to travel satisfaction (general evaluation of travel) and travel affect (emotions during travel) in car-dependent compact cities. Thereby, the study provides evidence on sustainable mobility and travel-related well-being in a context of compact urban form but inadequate provisions for public transport, walking, and cycling. A mixed-methods approach was applied comprising quantitative and qualitative analyses of data from the two major cities of Greece, i.e., Athens and Thessaloniki. Travel satisfaction and travel affect are found to be highest for those who walk for commuting, independently of travel time and other factors. Conversely, travel satisfaction and travel affect are lowest for public transport users, largely due to very long travel times but also poor public transport services in one of the two cities. Results indicate that the experience of traveling by public transport, car, and motorcycle within urban areas greatly depends on transport provision and policies. Overall, findings support the idea that to shift to pleasant, satisfying, and sustainable mobility in car-dependent compact cities, car restrictions should be accompanied by massive improvements in public transport, high-quality walking and cycling infrastructure, and an integrated coordination of different modes

    Characterizations, Sub and Resampling, and Goodness of Fit

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    We present a general proposal for testing for goodness of fit, based on resampling and subsampling methods, and illustrate it with graphical and analytical tests for the problems of testing for univariate or multivariate normality. The proposal shows promising, and in some cases dramatic, success in detecting nonnormality. Compared to common competitors, such as a Q-Q plot or a likelihood ratio test against a specified alternative, our proposal seems to be the most useful when the sample size is small, such as 10 or 12, or even very small, such as 6! We also show how our proposal provides tangible information about the nature of the true cdf from which one is sampling. Thus, our proposal also has data analytic value. Although only the normality problem is addressed here, the scope of application of the general proposal should be much broader

    Yoghurt Acid Whey Marination - The Case of Lamb and Beef Meat

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    Yoghurt acid whey (YAW) is an effluent of yoghurt production and is related with enhanced risk of environmental pollution due to its great organic matter levels, which elicit an increased bio-logical oxygen demand. During the previous decades a great effort has been exerted in finding sustainable applications of YAW. Therefore, YAW utilization in meat processing industry could be considered as a feasible option, since immersion of meat in marinades made of natural compounds is a process that is in  constant  advance  due  to  its  beneficial  implications  on  meat  organoleptic characteristics. In the present study, several quality traits and oxidation status of beef and sheep meat were evaluated after their marination into YAW. Forty samples for each meat type were assigned at random to one of five following treatments: CON, in the absence of marination; T1 and T3, where meat was immersed into YAW for 15 and 10 h at 4℃ (pH of 4.5), respectively, or T2 and T4, where samples were treated as in the T1 and T3 group, respectively, while carvacrol was also incorporated at 0.5 g/L. As shown, meat shear force value was decreased as a result of YAW marination for 15 h in beef and sheep meat samples, while the other quality characteristics (pH, color, cooking loss) were not dramatically influenced. On the other hand, meat oxidative stability was also improved in both meat types. As it can be pointed out, beef and sheep meat soaking into YAW for 15 h improves tenderness, however this is not evident in case of 10 h of immersion. At the same time, oxidative stability was also improved as a consequence of YAW marination especially in beef meat and lower MDA values of lamb meat were observed in carvacrol supplemented groups
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