A 15-Channel receive array and 16 channel detunable transmit coil for human brain imaging at 9.4T

The radio frequency (RF) magnetic field (B1) distribution becomes more complex in MR experiments employing higher static magnetic field (B0) due to shorter wavelength in tissue. The B1 + inhomogeneities from a predefined volume of interest is reduced by influencing the amplitude and phase of the transmit current on a transceiver array coil [1, 2]. Significant gains in SNR was achieved at 7T using 32 channel receive arrays assembled on close fitting formers [3, 4]. In this study, we combine the benefits of these two methods for human brain MRI at 9.4T (400MHz). Our imaging setup consists of a 15-element receive array together with a 16-element actively detunable transmit array and hence the additional flexibility to employ RF shimming methods

Homomorphic polynomial evaluation using Galois structure and applications to BFV bootstrapping

BGV and BFV are among the most widely used fully homomorphic encryption (FHE) schemes. Both schemes have a common plaintext space, with a rich algebraic structure. Our main contribution is to show how this structure can be exploited to more efficiently homomorphically evaluate polynomials. Namely, using Galois automorphisms, we present an algorithm to homomorphically evaluate a polynomial of degree $d$ in only $3\log(d)$ (in some cases only $2\log(d)$) many ciphertext-ciphertext multiplications and automorphism evaluations, where $d$ is bounded by the ring degree. In other words, as long as the degree of the polynomial is bounded, we achieve an exponential speedup compared to the state of the art. In particular, the approach also improves on the theoretical lower bound of $2\sqrt{d}$ many ciphertext-ciphertext multiplications, which would apply if automorphisms were not available. We investigate how to apply our improved polynomial evaluation to the bootstrapping procedure for BFV, and show that we are able to significantly improve its performance. We demonstrate this by providing an implementation of our improved BFV bootstrapping using the Microsoft SEAL library. More concretely, we obtain a $1.6\times$ speed up compared to the prior implementation given by Chen and Han (Eurocrypt 2018). The techniques are independent of, and can be combined with, the more recent optimisations presented by Geelen et al. (Eurocrypt 2023). As an additional contribution, we show how the bootstrapping approach used in schemes such as FHEW and TFHE can be applied in the BFV context. In particular, we demonstrate that programmable bootstrapping can be achieved for BFV. Moreover, we show how this bootstrapping approach can be improved in the BFV context to make better use of the Galois structure. However, we estimate that its complexity is around three orders of magnitude slower than the classical approach to BFV bootstrapping

Lattice Enumeration on GPUs for fplll

The Kannan-Fincke-Pohst lattice enumeration algorithm is the classical method for solving the shortest vector problem in lattices. It is also a fundamental tool for most lattice reduction algorithms that provide speed-length tradeoffs. As this algorithm allows efficient parallel implementations, it is likely that implementing it on modern graphics processing units (GPUs) can significantly improve performance. We provide such an implementation that is compatible with the fplll lattice reduction library [fplll16] and achieves a considerable speedup in higher lattice dimensions, compared to current, multithreaded versions. For this, we use the CUDA technology that provides an abstract language for programming GPUs. [fplll16] The FPLLL development team. “fplll, a lattice reduction library”. 2016. URL: https://github.com/fplll/fpll

SISTEMA DE CONTROLE INTERNO NA ADMINISTRAÇÃO PÚBLICA FEDERAL

O controle pode ser compreendido como uma maneira de fazer com que umdeterminado resultado seja atingido por intermédio da execução de tarefascujas rotinas são predeterminadas em normas. A fiscalização contábilfinanceira e orçamentária, operacional e patrimonial, segundo a Constituição noâmbito da União será exercida através de dois controles: o externo e o interno.Nessa perspectiva, o objetivo da presente pesquisa é identificar se o Sistemade Controle Interno contribui para que haja uma eficiente execução daspropostas de governo, diminuindo os riscos inerentes ao desvio de recursose/ou a aplicação irregular de dinheiro público. A análise da eficiência docontrole interno das instituições públicas federais representa, nesse sentido,uma ferramenta capaz de melhorar aplicação do dinheiro público

Towards Practical Doubly-Efficient Private Information Retrieval

Private information retrieval (PIR) protocols allow clients to access database entries without revealing the queried indices. They have many real-world applications, including privately querying patent-, compromised credential-, and contact databases. While existing PIR protocols that have been implemented perform reasonably well in practice, they all have suboptimal asymptotic complexities. A line of work has explored so-called doubly-efficient PIR (DEPIR), which refers to single-server PIR protocols with optimal asymptotic complexities. Recently, Lin, Mook, and Wichs (STOC 2023) presented the first protocol that completely satisfies the DEPIR constraints and can be rigorously proven secure. Unfortunately, their proposal is purely theoretical in nature. It is even speculated that such protocols are completely impractical, and hence no implementation of any DEPIR protocol exists. In this work, we challenge this assumption. We propose several optimizations for the protocol of Lin, Mook, and Wichs that improve both asymptotic and concrete running times, as well as storage requirements, by orders of magnitude. Furthermore, we implement the resulting protocol and show that for batch queries it outperforms state-of-the-art protocols

Paramagnetic lanthanide chelates for multicontrast MRI

[Abstract] The preparation of a paramagnetic chelator that serves as a platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or 19F MRI contrast agent is reported. Its europium(III) complex exhibits an extremely slow water exchange rate which is optimal for the use in CEST MRI. The potential of this platform was demonstrated through a series of MRI studies on tube phantoms and animals.Ministerio de Economía y Competitividad; CTQ2013-43243-PMinisterio de Economía y Competitividad; CTQ2015-71211-RED

GENTEL : GENerating Training data Efficiently for Learning to segment medical images

International audienceAccurately segmenting MRI images is crucial for many clinical applications. However, manually segmenting images with accurate pixel precision is a tedious and time consuming task. In this paper we present a simple, yet effective method to improve the efficiency of the image segmentation process. We propose to transform the image annotation task into a binary choice task. We start by using classical image processing algorithms with different parameter values to generate multiple, different segmentation masks for each input MRI image. Then, the user, instead of segmenting the pixels of the images, she/he only needs to decide if a segmentation is acceptable or not. This method allows us to efficiently obtain high quality segmentations with minor human intervention. With the selected segmentations we train a state-of-the-art neural network model. For the evaluation, we use a second MRI dataset (1.5T Dataset), acquired with a different protocol and containing annotations. We show that the trained network i) is capable to automatically segment cases where none of the classical methods obtained a high quality result ii) generalizes to the second MRI dataset, which was acquired with a different protocol and never seen at training time ; and iii) allows to detect miss-annotations in this second dataset. Quantitatively, the trained network obtains very good results : DICE score - mean 0.98, median 0.99- and Hausdorff distance (in pixels) - mean 4.7, median 2.0-.La segmentation précise d'images à résonnance magnétiques (IRM) est cruciale pour de nombreuses applications cliniques. Cependant, une segmentation manuelle visant une précision au niveau du pixel est une tâche longue et fastidieuse. Dans cet article, nous proposons une méthode simple pour améliorer l'efficacité de la segmentation d'images. Nous proposons de transformer la tâche d'annotation d'une image en une tâche de choix binaire. D'abord, nous utilisons plusieurs algorithmes classiques de traitement d'image pour générer plusieurs candidats de masques de segmentation. Ensuite, l'utilisat.eur.rice, au lieu de segmenter les pixels des images, décide si une segmentation est acceptable ou non. Cette méthode nous permet d'obtenir efficacement un grand nombre de segmentations de haute qualité avec une intervention humaine li-mitée. Avec les images et leurs segmentations sélectionnées, nous entrainons un réseau de neurones de l'état de l'art qui prédit les segmentations à partir des images d'entrée. Nous le validons sur un autre jeu de données IRM, acquis avec un protocole différent, et qui contient des segmentations. Nous montrons que le réseau entrainé 1) est capable de segmenter automatiquement des cas où aucune des méthodes classiques n'a obtenu un résultat de haute qualité, 2) est capable de segmenter un autre jeu de don-nées IRM, acquis avec un protocole différent et jamais vu lors de l'entrainement, et 3) permet de détecter des annotations erronées dans ce jeu de données. Quantitativement, le réseau entrainé obtient de très bons résultats : Score DICE-moyenne 0,98 et médiane 0,99-et distance de Hausdorff (en pixels)-moyenne 4,7, médiane 2,0

Temporal SNR characteristics in segmented 3D-EPI at 7T.

Three-dimensional segmented echo planar imaging (3D-EPI) is a promising approach for high-resolution functional magnetic resonance imaging, as it provides an increased signal-to-noise ratio (SNR) at similar temporal resolution to traditional multislice 2D-EPI readouts. Recently, the 3D-EPI technique has become more frequently used and it is important to better understand its implications for fMRI. In this study, the temporal SNR characteristics of 3D-EPI with varying numbers of segments are studied. It is shown that, in humans, the temporal variance increases with the number of segments used to form the EPI acquisition and that for segmented acquisitions, the maximum available temporal SNR is reduced compared to single shot acquisitions. This reduction with increased segmentation is not found in phantom data and thus likely due to physiological processes. When operating in the thermal noise dominated regime, fMRI experiments with a motor task revealed that the 3D variant outperforms the 2D-EPI in terms of temporal SNR and sensitivity to detect activated brain regions. Thus, the theoretical SNR advantage of a segmented 3D-EPI sequence for fMRI only exists in a low SNR situation. However, other advantages of 3D-EPI, such as the application of parallel imaging techniques in two dimensions and the low specific absorption rate requirements, may encourage the use of the 3D-EPI sequence for fMRI in situations with higher SNR

Single acquisition electrical property mapping based on relative coil sensitivities: A proof-of-concept demonstration.

PURPOSE: All methods presented to date to map both conductivity and permittivity rely on multiple acquisitions to compute quantitatively the magnitude of radiofrequency transmit fields, B1+. In this work, we propose a method to compute both conductivity and permittivity based solely on relative receive coil sensitivities ( B1-) that can be obtained in one single measurement without the need to neither explicitly perform transmit/receive phase separation nor make assumptions regarding those phases. THEORY AND METHODS: To demonstrate the validity and the noise sensitivity of our method we used electromagnetic finite differences simulations of a 16-channel transceiver array. To experimentally validate our methodology at 7 Tesla, multi compartment phantom data was acquired using a standard 32-channel receive coil system and two-dimensional (2D) and 3D gradient echo acquisition. The reconstructed electric properties were correlated to those measured using dielectric probes. RESULTS: The method was demonstrated both in simulations and in phantom data with correlations to both the modeled and bench measurements being close to identity. The noise properties were modeled and understood. CONCLUSION: The proposed methodology allows to quantitatively determine the electrical properties of a sample using any MR contrast, with the only constraint being the need to have 4 or more receive coils and high SNR. Magn Reson Med, 2014. © 2014 Wiley Periodicals, Inc