Economic evaluation of osteoporosis screening strategy conducted in the Province of Liège with the cooperation of Liège Province Santé

peer reviewedThe Province of Liege has conducted an osteoporosis screening strategy for women aged 50 to 69 years. The objective of this study is to investigate the economic characteristics of the screening strategy and to assess its cost-effectiveness, using a Markov microsimulation model. Our analyses suggest that the osteoporosis screening strategy is efficient if the medical community and the patients fulfill the recommendations of the Province of Liege health authorities and if persistence is optimized. Therefore, bone mineral density (BMD) measurement should be performed in all individuals with positive ultrasound screening; individuals having a positive BMD diagnosis should be treated and adherence to therapy should be increased. Furthermore, to improve the efficiency of the screening strategy, we suggest to target screening on women with one or more clinical risk factors, or on women aged 65 years and older

The Large Hadron-Electron Collider at the HL-LHC

The Large Hadron-Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron-proton and proton-proton operations. This report represents an update to the LHeC's conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LHeC will open a new chapter of nuclear particle physics by extending the accessible kinematic range of lepton-nucleus scattering by several orders of magnitude. Due to its enhanced luminosity and large energy and the cleanliness of the final hadronic states, the LHeC has a strong Higgs physics programme and its own discovery potential for new physics. Building on the 2012 CDR, this report contains a detailed updated design for the energy-recovery electron linac (ERL), including a new lattice, magnet and superconducting radio-frequency technology, and further components. Challenges of energy recovery are described, and the lower-energy, high-current, three-turn ERL facility, PERLE at Orsay, is presented, which uses the LHeC characteristics serving as a development facility for the design and operation of the LHeC. An updated detector design is presented corresponding to the acceptance, resolution, and calibration goals that arise from the Higgs and parton-density-function physics programmes. This paper also presents novel results for the Future Circular Collider in electron-hadron (FCC-eh) mode, which utilises the same ERL technology to further extend the reach of DIS to even higher centre-of-mass energies.Peer reviewe

The Large Hadron–Electron Collider at the HL-LHC

The Large Hadron–Electron Collider (LHeC) is designed to move the field of deep inelastic scattering (DIS) to the energy and intensity frontier of particle physics. Exploiting energy-recovery technology, it collides a novel, intense electron beam with a proton or ion beam from the High-Luminosity Large Hadron Collider (HL-LHC). The accelerator and interaction region are designed for concurrent electron–proton and proton–proton operations. This report represents an update to the LHeC’s conceptual design report (CDR), published in 2012. It comprises new results on the parton structure of the proton and heavier nuclei, QCD dynamics, and electroweak and top-quark physics. It is shown how the LHeC will open a new chapter of nuclear particle physics by extending the accessible kinematic range of lepton–nucleus scattering by several orders of magnitude. Due to its enhanced luminosity and large energy and the cleanliness of the final hadronic states, the LHeC has a strong Higgs physics programme and its own discovery potential for new physics. Building on the 2012 CDR, this report contains a detailed updated design for the energy-recovery electron linac (ERL), including a new lattice, magnet and superconducting radio-frequency technology, and further components. Challenges of energy recovery are described, and the lower-energy, high-current, three-turn ERL facility, PERLE at Orsay, is presented, which uses the LHeC characteristics serving as a development facility for the design and operation of the LHeC. An updated detector design is presented corresponding to the acceptance, resolution, and calibration goals that arise from the Higgs and parton-density-function physics programmes. This paper also presents novel results for the Future Circular Collider in electron–hadron (FCC-eh) mode, which utilises the same ERL technology to further extend the reach of DIS to even higher centre-of-mass energies

Gérer le changement dans une logique participative: Apports du leadership transformationnel

Dans leur conférence - débat, Olivier Lisein (LENTIC - HEC Liège - ULiège) et Jean-Louis Pire (HEC Liège Executive Education) questionneront les pratiques actuelles de gestion du changement, mettront en évidence les limites des approches traditionnelles et insisteront sur l’importance d’une implication continue des parties prenantes dans les processus de changement. Ils montreront la plus-value que peuvent retirer les gestionnaires de projets d’une logique participative et d’une approche basée sur la « co-construction », avec les acteurs concernés, des projets de changement. Ils insisteront également sur l’importance que revêt le leadership transformationnel dans ce cadre ainsi que sur le rôle que les équipes managériales ont à jouer pour favoriser des dynamiques de changement réussies et socialement responsables

Gérer le changement dans une logique participative: défis et enjeux du leadership transformationnel

Mettre en œuvre des pratiques de gestion du changement efficaces, qui intègrent impératifs stratégiques, enjeux organisationnels et respect des parties prenantes, est devenu une obligation pour les entreprises contemporaines, aujourd’hui inscrites dans des logiques d’implémentation quasi-continue de projets de changement. L’intervention conjointe d’Olivier Lisein (LENTIC, HEC Liège) et de Jean-Louis Pire (HEC Liège Executive Education) permettra de faire le point sur cette question. En particulier, Olivier Lisein questionnera les pratiques actuelles de gestion du changement, mettra en évidence les limites des approches traditionnelles en la matière et insistera sur l’importance d’une implication continue des parties prenantes dans les processus de changement. Il montrera à ce titre la plus-value que peuvent retirer les gestionnaires de projets d’une logique participative et d’une approche basée sur la « co-construction », avec les acteurs concernés, des projets de changement. De son côté, Jean-Louis Pire insistera sur l’importance que revêt le leadership transformationnel dans ce cadre. Si identifier et impliquer les parties prenantes est une chose, les mobiliser concrètement et efficacement dans la co-construction des projets de changement en est une autre. Jean-Louis Pire mettra notamment en avant le rôle clé que joue le responsable de projet en la matière ainsi que l’importance de son leadership transformationnel, nécessaire afin de mobiliser les acteurs dans les processus de changement et de favoriser leur appropriation des innovations mises en place. Les interventions d’Olivier Lisein et de Jean-Louis Pire seront à la fois conceptuelles et pratiques, illustrées d’exemples concrets de projets de changement accompagnés récemment

Efficiency and recommendations for osteoporosis screening strategy

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Evaluation of a campaign for osteoporosis screening in the general population: what is the follow-up given by general practitioners to a positive screening result?

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