Eficácia dos indicadores de alerta precoce do RFALEI na identificação dos municípios que ultrapassaram o limite ao endividamento

A necessidade de gerir a dívida dos municípios traduz-se, em Portugal, na existência de um framework legal consubstanciado, nomeadamente, no respetivo regime financeiro. O regime em vigor (desde 2014), estabelece limites à divida total e define mecanismos de prevenção do endividamento. Esta investigação analisou os municípios portugueses que ultrapassaram o limite ao endividamento e, em que medida, aqueles indicadores de alerta precoce permitem identificar a situação de incumprimento em cada um dos períodos estudados (2011 a 2013 e 2014 a 2016). O indicador da taxa execução da receita tem vindo a melhorar significativamente desde 2014, parecendo estar a contribuir para a elaboração de orçamentos menos sobreavaliados. Quanto à eficácia dos indicadores, conclui-se que no período de 2014 a 2016, ambos são estatisticamente significativos em termos de correlação. No entanto, o indicador “dívida total maior ou igual à média da receita corrente” revelou-se mais eficaz na identificação dos municípios em incumprimento

Determinantes do índice de transparência municipal em Portugal (2013 a 2017)

A transparência assenta na disponibilização de informação sobre a gestão, sendo imprescindível a uma boa governação pública. Dada a divulgação do Índice de Transparência Municipal (ITM) relativo aos anos de 2013 a 2017, a presente investigação tem como objetivo estudar as determinantes que influenciam este índice, naquele período. Para a realização do estudo utilizaram-se dados dos 308 municípios portugueses, sendo o valor do ITM a variável que se pretende explicar. Para a respetiva análise, recorreu-se à análise estatística via modelos de regressão linear múltipla com dados em painel. Como principal conclusão da investigação realizada retira-se que as variáveis despesa efetiva per capita, taxa de população idosa e percentagem de abstenção, demonstraram ser determinantes do índice de transparência municipal para os anos em análise. O presente estudo pretende contribuir para o conhecimento no âmbito da transparência dos governos locais em Portugal

COMPARAÇÃO BIOMECÂNICA DA CORRIDA ENTRE INDIVÍDUOS COM DIFERENTES NÍVEIS DE FORÇA DE MEMBROS INFERIORES

Running is a practice widely used by those who aim to maintain or improve their physical fitness. Strength training has been recommended to increase performance and reduce injury risk in runners, however, the relationship between muscle strength and running mechanics still requires a better understanding. The aim of the present study was to compare the running biomechanics among bodybuilders, with different levels of absolute strength in the back squat. Initially, 24 volunteers participated in the study. Based on the 10RM absolute strength in the back squat, the volunteers were divided into tertiles: upper strength group (GFS), lower strength group (GFI) and medium strength group. For comparison of running mechanics, GFS and GFI were gained. Dynamic and kinematic parameters were collected during treadmill running. There were no differences between groups for any of the investigated variables. Keywords: Running mechanics; Muscle strength; Locomotion.Correr es una práctica muy utilizada por quienes tienen como objetivo mantener o mejorar su forma física. El entrenamiento de fuerza se ha recomendado como una forma de aumentar el rendimiento y reducir el riesgo de lesiones en los corredores, sin embargo, la relación entre la fuerza muscular y la mecánica de carrera aún requiere una mejor comprensión. El objetivo del presente estudio fue comparar la biomecánica de la carrera entre culturistas, con diferentes niveles de fuerza absoluta en la sentadilla. Inicialmente, participaron en el estudio 24 voluntarios. Con base en la fuerza absoluta de 10RM en la sentadilla, los voluntarios se dividieron en terciles: grupo de fuerza superior (GFS), grupo de fuerza inferior (GFI) y grupo de fuerza media. Para comparar la mecánica de la carrera, se obtuvieron GFS y GFI. Los parámetros dinámicos y cinemáticos se recopilaron durante la carrera en cinta. No hubo diferencias entre los grupos para ninguna de las variables investigadas. Palabras clave: mecánica de carrera; Fuerza muscular; Locomoción.A corrida é uma prática largamente utilizada por aqueles que almejam manter ou aprimorar a aptidão física. O treinamento de força tem sido recomendado como forma de aumentar o desempenho e reduzir o risco de lesão em praticantes de corrida, no entanto, a relação entre força muscular e mecânica da corrida ainda necessita de melhor compreensão. O objetivo do presente estudo foi comparar a biomecânica da corrida entre indivíduos praticantes de musculação, com diferentes níveis de força absoluta no agachamento. Inicialmente participaram do estudo 24 voluntários. Baseado na força absoluta em 10RM no agachamento, os voluntários foram divididos em tercis: grupo de força superior (GFS), grupo de força inferior (GFI) e grupo de força mediana. Para comparação da mecânica da corrida foram analisados o GFS e GFI. Foram coletados parâmetros dinâmicos e cinemáticos durante corrida em esteira. Não se observou diferenças entre os grupos para nenhuma das variáveis investigadas. Palavras-chave: Mecânica da corrida; Força muscular; Locomoção

IMPACTO DE VARIÁVEIS CONGNITIVAS E CONTEXTUAIS SOBRE O SUCESSO ACADÊMICO E O BEM ESTAR NA UNIVERSIDADE – QUE FAZER? QUE DEIXAR DE FAZER?

Este estudo parte de uma investigação longitudinal (2019-2022) mais ampla, vinculada ao Grupo Multidisciplinar de Pesquisa em Educação, Psicopedagogia e Psicologia Escolar, UFAM/CNPq, PROCAD/AMAZÔNIA-PPGEUFAM/UFPA/UFMT, Processo CAPES 8881.314288/2019-0, articula-se metodológica e teoricamente com interfaces entre a psicologia escolar, psicologia educacional, pedagogia do ensino superior e educação escolar. Atua no sentido de entender os efeitos de variáveis cognitivas e contextuais sobre o sucesso acadêmico e o bem estar na universidade. A metodologia para coleta de dados é a aplicação de caderno de instrumentos próprios com apoio do Googleodocs, a amostra atual é de n=1112 estudantes de diferentes países (Brasil, México, República Dominicana, Bolívia, Moçambique, Angola, Venezuela, Colômbia, Espanha e Portugal), do sexo masculino e feminino, idade entre 18 e 54 anos e de 51 universidades públicas e privadas que colaboram com a iniciativa. Os dados são analisados com auxílio do Excel e SPSS, de acordo com os interesses dos pesquisadores e objetivos da investigação. Os resultados atuais demonstram a importância da pesquisa sobre os temas abordados pela iniciativa considerando o impacto das variáveis estudadas sobre o rendimento acadêmico e bom estar tanto de estudantes como de docentes e técnicos no ensino superior. Foram identificadas diferenças de países, renda, etnia, gênero e renda. No caso dos docentes e técnicos verificamos evidências da exaustão feminina. Os resultados podem apoiar a administração geral e coordenação educativa e psicopedagógica universitária em sentido amplo, visando a melhoria dos indicadores de sucesso acadêmico e bem estar, por meio da proposição de novas políticas e gestão da educação superior. Palavras-chave: Pesquisa em educação, Ensino superior, Rendimento acadêmico, Bem estar. Políticas de gestão da educação superior. Educação comparada.   IMPACT OF COGNITIVE AND CONTEXTUAL VARIABLES ABOUT ACADEMIC PERFORMANCE AND  WELLBEING IN THE UNIVERSITY. Whato to do? Qhato not to do?   Abstract: This study, part of a further longitudinal investigation (2019-2022), attached to a multidisciplinary group of Educational Research  Scholar Psychotherapy and Psychology, UFAM/CNPq, PROCAD/AMAZONIA-PPGEUFAM/UFPA/UFMT, CAPES process 8881.314288/2019-0, it is articulated methodological and theoretically with interfaces between the scholar and educational psychology, upper and scholar education pedagogy. It acts in the direction of understanding 5he effects og cognitive and contextual variables about the academic achievement and wellness in the university. The methodology to data collection is the application of own instrument cards with the support of Googledocs, the actual sample is quantity of n=1112 students from 51 private and public universities of different countries (Brazil, Mexico, Dominican Republic, Bolivia, Mozambique, Angola, Venezuela, Colombia, Spain and Portugal), from both male and female genders, aging between 18 and 54 years-old. The data were analyzed with the support of software Excel and SPSS, according to the interests of researchers and investigation focus. The actual results show the importance of the research about the themes cited in the initiative considering the impacts of the studied variables over the academic performance and wellness of the students as the teachers and technicians from upper education. There were found differences between countries, income, ethnic and gender. In the cases of the teachers and technicians it was found evidences of female exhaustion. The results could support the general administration, educative and psychopedagogy coordination and in a wide range, looking forward the better successful academic indicators and wellness, through the proposition of new policies and management of upper education. Keywords: Educational Reserch, upper educatión, academic performance, wellness, upper educaciton mangement policies, compared education. &nbsp

Considerações gerais sobre a síncope: uma abordagem clínica : General considerations about syncope: a clinical approach

O seguinte estudo objetivou descrever sobre as etiologias e o respectivo quadro clínico da síncope. A síncope é classificado como um sintoma de perda da consciência devido redução do fluxo sanguíneo cerebral, secundário a uma etiologia. Tal evento costuma ser confundido com outras condições associadas a perda de conhecimento, apesar de para se diagnosticar como síncope é necessário descartar demais alterações. A síncope é uma condição que têm como fisiopatologia o hipofluxo de sangue no cérebro, mas conta com diversas causas como a neuromediada, ortostática, cardíaca, cerebrovascular e até idiopática,  resultam em quadros clínicos distintos e complicações, mas o mesmo desfecho. Tal evento necessita ser investigado e detectado de imediato, por história clínica, exame físico e complementares

Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil

Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome sequencing of viruses sampled in Manaus between November 2020 and January 2021 revealed the emergence and circulation of a novel SARS-CoV-2 variant of concern. Lineage P.1 acquired 17 mutations, including a trio in the spike protein (K417T, E484K, and N501Y) associated with increased binding to the human ACE2 (angiotensin-converting enzyme 2) receptor. Molecular clock analysis shows that P.1 emergence occurred around mid-November 2020 and was preceded by a period of faster molecular evolution. Using a two-category dynamical model that integrates genomic and mortality data, we estimate that P.1 may be 1.7- to 2.4-fold more transmissible and that previous (non-P.1) infection provides 54 to 79% of the protection against infection with P.1 that it provides against non-P.1 lineages. Enhanced global genomic surveillance of variants of concern, which may exhibit increased transmissibility and/or immune evasion, is critical to accelerate pandemic responsiveness

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

As mortality rates decline, life expectancy increases, and populations age, non-fatal outcomes of diseases and injuries are becoming a larger component of the global burden of disease. The Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016) provides a comprehensive assessment of prevalence, incidence, and years lived with disability (YLDs) for 328 causes in 195 countries and territories from 1990 to 2016

Global, regional, and national disability-adjusted life-years (DALYs) for 333 diseases and injuries and healthy life expectancy (HALE) for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

BACKGROUND: Measurement of changes in health across locations is useful to compare and contrast changing epidemiological patterns against health system performance and identify specific needs for resource allocation in research, policy development, and programme decision making. Using the Global Burden of Diseases, Injuries, and Risk Factors Study 2016, we drew from two widely used summary measures to monitor such changes in population health: disability-adjusted life-years (DALYs) and healthy life expectancy (HALE). We used these measures to track trends and benchmark progress compared with expected trends on the basis of the Socio-demographic Index (SDI). METHODS: We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2016. We calculated DALYs by summing years of life lost and years of life lived with disability for each location, age group, sex, and year. We estimated HALE using age-specific death rates and years of life lived with disability per capita. We explored how DALYs and HALE differed from expected trends when compared with the SDI: the geometric mean of income per person, educational attainment in the population older than age 15 years, and total fertility rate. FINDINGS: The highest globally observed HALE at birth for both women and men was in Singapore, at 75·2 years (95% uncertainty interval 71·9-78·6) for females and 72·0 years (68·8-75·1) for males. The lowest for females was in the Central African Republic (45·6 years [42·0-49·5]) and for males was in Lesotho (41·5 years [39·0-44·0]). From 1990 to 2016, global HALE increased by an average of 6·24 years (5·97-6·48) for both sexes combined. Global HALE increased by 6·04 years (5·74-6·27) for males and 6·49 years (6·08-6·77) for females, whereas HALE at age 65 years increased by 1·78 years (1·61-1·93) for males and 1·96 years (1·69-2·13) for females. Total global DALYs remained largely unchanged from 1990 to 2016 (-2·3% [-5·9 to 0·9]), with decreases in communicable, maternal, neonatal, and nutritional (CMNN) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). The exemplars, calculated as the five lowest ratios of observed to expected age-standardised DALY rates in 2016, were Nicaragua, Costa Rica, the Maldives, Peru, and Israel. The leading three causes of DALYs globally were ischaemic heart disease, cerebrovascular disease, and lower respiratory infections, comprising 16·1% of all DALYs. Total DALYs and age-standardised DALY rates due to most CMNN causes decreased from 1990 to 2016. Conversely, the total DALY burden rose for most NCDs; however, age-standardised DALY rates due to NCDs declined globally. INTERPRETATION: At a global level, DALYs and HALE continue to show improvements. At the same time, we observe that many populations are facing growing functional health loss. Rising SDI was associated with increases in cumulative years of life lived with disability and decreases in CMNN DALYs offset by increased NCD DALYs. Relative compression of morbidity highlights the importance of continued health interventions, which has changed in most locations in pace with the gross domestic product per person, education, and family planning. The analysis of DALYs and HALE and their relationship to SDI represents a robust framework with which to benchmark location-specific health performance. Country-specific drivers of disease burden, particularly for causes with higher-than-expected DALYs, should inform health policies, health system improvement initiatives, targeted prevention efforts, and development assistance for health, including financial and research investments for all countries, regardless of their level of sociodemographic development. The presence of countries that substantially outperform others suggests the need for increased scrutiny for proven examples of best practices, which can help to extend gains, whereas the presence of underperforming countries suggests the need for devotion of extra attention to health systems that need more robust support. FUNDING: Bill & Melinda Gates Foundation