Ipil-ipil (Leucaena leucocephala) leaves as a plant protein source in prawn diets

Penaeus monodon juveniles were fed diets containing fish meal, shrimp head meal and ipil-ipil leaves soaked and unsoaked, local and peruvian varieties. Mean weight gain at the end of 8 wk was significantly highest among those given the diet containing commercial ipil-ipil leaves. Gain in length followed the same pattern as mean weight gains. Among the diets containing ipil-ipil leaves there was a direct relationship in the amount of mimosine in the diet and the survival rate, the lower the amount of mimosine (due to soaking) the higher the survival rate. The Results thus indicate the beneficial effect of the addition of commercial ipil-ipil leaves to the diets of prawns, providing the mimosine content is kept low by soaking. A reduce in costs is also obtained, since 1kg of shrimp head meal or fish costs more than 2 or 4 tons, respectively, than that of ipil-ipil foliage

Growth and survival of Penaeus monodon postlarvae fed shrimp head meal and fish meal as primary animal source of protein

Although shrimp head meal alone does not provide for good growth and survival, fish meal can provide high survival rate. The addition of shrimp head improves this diet. It is suggested that cholesterol present in shrimp could have caused this difference. Composition of the test diets is tabulated, as are proximate chemical analysis of the diets, and the mean initial weights, final weights, weight gains, survival rate, feed consumed, protein consumed, of Penaeus monodon postlarvae, feed conversion and protein efficiency ratio

The effect of different binders on the water stability of feeds for prawn

Corn starch, gelatin, sago palm starch, agar, and bread flour were tested for their binding capacity in pelleted diets for Penaeus monodon . Agar was found to be good binder, but it costs too much, while bread flour was also good but as it's commonly used for human comsumption its use for animal feed should be minimized. The use of 20% bread flour, or a combination of 5% sago palm starch or corn starch with 15% bread flour is recommended, depending on the cost and availability. Basic composition of the formulated diet is tabulated, as is water stability of 2 and 4 mm diameter steamed pellets after 2, 6 and 18 h

A tandem process for in situ H2O2 formation coupled with benzyl alcohol oxidation using Pd-Au bimetallic catalysts

[EN] Alcohol oxidation is one of the most important industrial organic reactions. Traditionally, the best-suited catalysts are Pd, Pt and Au supported nanoparticles. The research community has recently started developing strategies for synthesizing carbon-supported Pd/Au bimetallic nanoparticles (NPs), leading to higher activities and selectivities. However, the metallic active species in these catalysts are usually generated using sodium borohydride (NaBH4), which is not synthetically easy to reproduce. In fact, minor modifications in pH, concentration and/or other parameters have a prominent effect on the nature of the promoted material. In this work, a robust process involving dihydrogen flow (H2) at 200 °C as a reducing agent for synthesizing Pd/Au supported bimetallic materials was considered an alternative to the common pathway. The physicochemical properties of the materials derived from different reducing reagents and of varying composition ranges were studied using HR-TEM, XRD, CO chemisorption, and XPS. Their stability and activity were also tested for benzyl alcohol oxidation to benzaldehyde under mild reaction conditions (60 °C, water as the solvent, and PO2 = 1.5 bar). Notably, a catalyst from the hydrogen reduction process with a metal composition of 0.8%Pd¿0.2%Au/C consisting of bimetallic clusters (¿1.5 nm) proved to be the best material (C = 94%, S = 99%). Catalytic performances were strongly correlated with structural properties, such as nanoparticle size and distribution, which, in turn, were affected by the reduction step and the metal composition range. Finally, the influence of oxidants on benzyl alcohol oxidation has also been studied, along with the first approach for the tandem in situ formation of H2O2 coupled with alcohol oxidation.The authors are thankful for the financial support by the Spanish Government (RTI2018-096399-A-I00 and PGC2018-097277-B-I00 funded by MICINN/AEI/10.13039/501100011033) and Junta de Andalucia (P20 01027 and PYC 20 RE 060 UAL). The electron microscopy service of the UPV is acknowledged for their help in sample characterization.Martínez, JS.; Mazarío, J.; Gutiérrez-Tarriño, S.; Galdeano-Ruano, CP.; Gaona Miguélez, JA.; Domine, ME.; Oña-Burgos, P. (2022). A tandem process for in situ H2O2 formation coupled with benzyl alcohol oxidation using Pd-Au bimetallic catalysts. Dalton Transactions. 51(46):17567-17578. https://doi.org/10.1039/D2DT02831J1756717578514

Análisis de los factores de riesgo en el seguro de automóvil mediante ecuaciones estructurales

La gestión de riesgos, asociada al seguro del automóvil, es una cuestión crucial a la que se enfrentan en la actualidad tanto actuarios como profesionales del sector. Es clave seleccionar adecuadamente los factores de riesgos para asignar las tarifas a los asegurados en función del riesgo asociado. Por tanto, el objetivo de este trabajo es comprobar empíricamente la validez de la utilización de los niveles de “bonus-malus” para clasificar adecuadamente a los asegurados a través de dos modelos de ecuaciones estructurales. Los análisis sobre una muestra de 4.365 pólizas automovilísticas españolas descritas a través de 11 factores de riesgo muestran que la variable BM contribuye a mejorar la capacidad explicativa del modelo pero no de manera significativa

Análisis de los factores de riesgo en el seguro de automóvil mediante ecuaciones estructurales

La gestión de riesgos, asociada al seguro del automóvil, es una cuestión crucial a la que se enfrentan en la actualidad tanto actuarios como profesionales del sector. Es clave seleccionar adecuadamente los factores de riesgos para asignar las tarifas a los asegurados en función del riesgo asociado. Por tanto, el objetivo de este trabajo es comprobar empíricamente la validez de la utilización de los niveles de “bonus-malus” para clasificar adecuadamente a los asegurados a través de dos modelos de ecuaciones estructurales. Los análisis sobre una muestra de 4.365 pólizas automovilísticas españolas descritas a través de 11 factores de riesgo muestran que la variable BM contribuye a mejorar la capacidad explicativa del modelo pero no de manera significativa

Correlation between the values of the body mass index and the subscales of the Manchester: Foot Pain and Disability Index in patients with plantar fasciitis

[Resumen] Objetivo: determinar el impacto que sufren los pacientes con fascitis plantar crónica en relación a su Índice de Masa Corporal (IMC) basándonos en las subescalas incluidas en el Manchester Foot Pain and Disability Index (MFPDI) (“subescalas del dolor”, “subescalas de limitación funcional” y “subescala de discapacidad”). Material y métodos: Se realizó un estudio observacional transversal con 17 participantes diagnosticados de fascitis plantar crónica. Se administró el cuestionario MFPDI y se establecieron relaciones entre el resultado obtenido de las subescalas y el IMC. Resultados: Únicamente hay diferencias estadísticamente significativas entre las variables “Subescala de dolor” del MFPDI (p-valor = 0,013) y “Subescala de limitación funcional” del MFPDI (p-valor = 0,03) en relación a la variable IMC. Conclusión: El incremento del IMC tiene un efecto significativo en el nivel de dolor y limitación funcional según lo determinador por el MFPDI en pacientes con fascitis plantar.[Abstract] Objective: The purpose of this study is to determine the relationship between the subcategories included in the Manchester Foot Pain and Disability Index (MFPDI) with Body Mass Index (BMI) in patients with plantar fasciitis. Methods: A cross-sectional observational study was performed with 17 participants who are suffering plantar fasciitis and administered the MFPDI in order to quantify the impact of plantar fasciitis. Results: Only there were statistically significant differences between the MFPDI subscale of pain (p-value = 0.013) and the functional limitation subscale of the MFPDI (p-value = 0.03) in relation to the BMI variable. Conclusion: Increased BMI has a significant effect on the level of pain and functional limitation as determined by MFPDI in patients with plantar fasciitis

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis

International audienceSepsis is characterized by a systemic inflammatory response followed by immunosuppres-sion of the host. Metabolic defects and mitochondrial failure are common in immunocom-promised patients with sepsis. The NLRP3 inflammasome is important for establishing an inflammatory response after activation by the purinergic P2X7 receptor. Here, we study a cohort of individuals with intra-abdominal origin sepsis and show that patient monocytes have impaired NLRP3 activation by the P2X7 receptor. Furthermore, most sepsis-related deaths are among patients whose NLRP3 activation is profoundly altered. In monocytes from sepsis patients, the P2X7 receptor is associated with mitochondrial dysfunction. Furthermore, activation of the P2X7 receptor results in mitochondrial damage, which in turn inhibits NLRP3 activation by HIF-1α. We show that mortality increases in a mouse model of sepsis when the P2X7 receptor is activated in vivo. These data reveal a molecular mechanism initiated by the P2X7 receptor that contributes to NLRP3 impairment during infection

Validation of processed animal proteins (mono-PAPS) in experimental diets for juvenile gilthead sea bream (Sparus aurata L.) as primary fish meal replacers within a European perspective

Experimental diets were formulated to evaluate a “pure” poultry meat meal (PMM) source in diets formulated for juvenile gilthead sea bream (Sparus aurata L.). The digestible protein contribution of fish meal in a control diet was substituted by 25%, 50% and 75% of a processed poultry meat meal (PMM) on a digestible crude protein (DCP) basis and by 5% and 10% for an enzyme‐treated feather meal (EFM) and also a spray‐dried haemaglobin meal (SDHM), respectively. In a consecutive trial, diets were designed to assess the value of a “pure” (defatted) poultry protein substituting the fish meal (FM) protein content. Experimental diets included: a control diet, two test diets where 75% of FM was replaced by a full‐fat PMM (PMM75) or a defatted grade of PMM (dPMM75) and two test diets where 50% of FM was substituted for defatted PMM (dPMM50) or a 50:50 blend of soya bean meal and defatted PMM (SBM/dPMM) to produce a composite product. This soya bean/dPMM blend was tested to enhance the nutritional value of this key plant ingredient commonly employed in sea bream diets that can be deficient in specific amino acids and minerals. In the first trial, gilthead sea bream grew effectively on diets containing up to the 75% replacement of FM attaining a mean weight of 63.6 g compared to 67.8 g for the FM control fed group. For the consecutive trial, the fishmeal‐based control diet yielded the highest SGR followed by dPMM50 and SBM/dPMM blend inclusion but was not significant. Carcass FA profiles of gilthead sea bream conformed to the expected changes in relation to the dietary FA patterns, with the 18:1n‐9 representative of the poultry lipid signature becoming more apparent with PMM inclusion. The ratio of n‐3/n‐6 fatty acids was greatly affected in sea bream fed the full‐fat PMM at 75% inclusion due to fish oil exclusion. Defatted dPMM, however, allowed more of the fish oil to be used in the diet and reducing this latter effect in sea bream carcass, hence restoring the higher total omega‐3 HUFA fatty acids namely EPA and DHA and n‐3/n‐6 ratio. It is concluded that poultry meat meal can be modestly incorporated into formulated diets for sea bream and can be used in conjunction with soya bean meal without any fundamental changes in performance and feed efficiency