Editorial

The University's Assessment, Learning and Teaching strategy commits us to publishing a journal showcasing staff activities in relation to Assessment, Learning and Teaching. The Assessment, Learning and Teaching Journal is practice-based, reflective and pragmatic, and comprises papers of up to 1,500 words and book reviews of up to 200 words. The journal is refereed, all submissions being reviewed by two reviewers. It is normally published three times a year both in hard copy and electronically

Late Miocene karst system at Sheikh Abdallah, between Bahariya and Farafra, Western Desert, Egypt : Implications for palaeoclimate and geomorphology

The extensive spelean deposits in the Western Desert of Egypt at Crystal Mountain (Gebel Bellorat) are considered to be 11-10 Ma, confirming the 'Vallesian' estimate made by Heissig (1982). Several new faunal elements have been discovered including anurans, snakes, soricids, bats, galagids, hystricids and glirids. This fauna indicates that the region was appreciably more humid 11-10 Ma than it is today, with at least 750 mm and possibly as much as 1,200 mm mean annual rainfall. The role of karst processes in the development of the oases of the Western Desert that may have been underestimated by previous researchers is emphasized

Primer ejemplar fósil de tipo nutria Amblonyx, con una nota sobre ejemplares de Lutra del Siwaliks Superior, India

Otter-like mammals have been reported from the Indian sub-continent for more than a century and a half. Enhydriodontini are far more common and have a longer fossil record than either Lutrini or Aonychini. This paper describes and interprets two fossils from the Pleistocene of Panchkula and Pipalwala, India. The Panchkula specimen represents a large species of Amblomyx (Aonychini) whereas the Pipalwala specimen is likely to represent a large individual of Lutra paleoindica (Lutrini).Mamíferos de tipo nutria han sido señalados en el subcontinente Indio desde hace más de un siglo y medio. Los Enhydriodontini son de lejos los más comunes y tienen un mayor registro fósil que los Lutrini o los Aonychini. En este trabajo describimos e interpretamos dos fósiles procedentes del Pleistoceno de Panchkula y Pipalwala, India. El ejemplar de Panchkula representa una especie de talla grande de Amblomyx (Aonychini), mientras que el ejemplar de Pipalwala representa a un individuo de talla grade de Lutra paleoindica (Lutrini)

On-plot sanitation in low-income urban communities: a review of the literature

More than three hundred documents were examined in this review and material relevant to on-plot urban sanitation has been summarized in sections dealing with technical, health and social, and management matters. Alternative technologies are critically reviewed, with special attention given to the relative advantages and disadvantages of each option

The kainate receptor antagonist UBP310 but not single deletion of GluK1, GluK2, or GluK3 subunits, inhibits MPTP-induced degeneration in the mouse midbrain

© 2019 Elsevier Inc. The excitatory neurotransmitter glutamate is essential in basal ganglia motor circuits and has long been thought to contribute to cell death and degeneration in Parkinson's disease (PD). While previous research has shown a significant role of NMDA and AMPA receptors in both excitotoxicity and PD, the third class of ionotropic glutamate receptors, kainate receptors, have been less well studied. Given the expression of kainate receptor subunits GluK1-GluK3 in key PD-related brain regions, it has been suggested that GluK1-GluK3 may contribute to excitotoxic cell loss. Therefore the neuroprotective potential of the kainate receptor antagonist UBP310 in animal models of PD was investigated in this study. Stereological quantification revealed administration of UBP310 significantly increased survival of dopaminergic and total neuron populations in the substantia nigra pars compacta in the acute MPTP mouse model of PD. In contrast, UBP310 was unable to rescue MPTP-induced loss of dopamine levels or dopamine transporter expression in the striatum. Furthermore, deletion of GluK1, GluK2 or GluK3 had no effect on MPTP or UBP310-mediated effects across all measures. Interestingly, UBP310 did not attenuate cell loss in the midbrain induced by intrastriatal 6-OHDA toxicity. These results indicate UBP310 provides neuroprotection in the midbrain against MPTP neurotoxicity that is not dependent on specific kainate receptor subunits

The introduction and refinement of the assessment of digitally recorded audio presentations

This case study critically evaluates benefits and challenges of a form of assessment included in a final year undergraduate Religious Studies Open University module, which combines a written essay task with a digital audio recording of a short oral presentation. Based on the analysis of student and tutor feedback and sample assignments, this study critically examines how teaching and learning practices linked to this novel form of assessment have been iteratively developed in light of the project findings over a period of two years. It concludes that while this form of assessment poses a number of challenges, it can create valuable opportunities for the development of transferable twenty-first-century graduate employability skills as well as deep, effective learning experiences, particularly – though not exclusively – in distance learning settings