2,487 research outputs found
Multiplane gravitational lenses with an abundance of images
We consider gravitational lensing of a background source by a finite system
of point-masses. The problem of determining the maximum possible number of
lensed images has been completely resolved in the single-plane setting (where
the point masses all reside in a single lens plane), but this problem remains
open in the multiplane setting. We construct examples of -plane point-mass
gravitational lens ensembles that produce images of a
single background source, where is the number of point masses in the
plane. This gives asymptotically (for large with fixed)
times the minimal number of lensed images. Our construction uses Rhie's
single-plane examples and a structured parameter-rescaling algorithm to produce
preliminary systems of equations with the desired number of solutions.
Utilizing the stability principle from differential topology, we then show that
the preliminary (nonphysical) examples can be perturbed to produce physically
meaningful examples while preserving the number of solutions. We provide
numerical simulations illustrating the result of our construction, including
the positions of lensed images as well as the structure of the critical curves
and caustics. We observe an interesting ``caustic of multiplicity'' phenomenon
that occurs in the nonphysical case and has a noticeable effect on the caustic
structure in the physically meaningful perturbative case.Comment: 20 pages, 8 figures. The paper will appear in the Journal of
Mathematical Physic
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Diamond Wire Cutting of the Tokamak Fusion Test Reactor
The Tokamak Fusion Test Reactor (TFTR) is a one-of-a-kind, tritium-fueled fusion research reactor that ceased operation in April 1997. As a result, decommissioning commenced in October 1999. The 100 cubic meter volume of the donut-shaped reactor makes it the second largest fusion reactor in the world. The deuterium-tritium experiments resulted in contaminating the vacuum vessel with tritium and activating the materials with 14 MeV neutrons. The total tritium content within the vessel is in excess of 7,000 Curies, while dose rates approach 50 mRem/hr. These radiological hazards along with the size of the tokamak present a unique and challenging task for dismantling. Engineers at the Princeton Plasma Physics Laboratory (PPPL) decided to investigate an alternate, innovative approach for dismantlement of the TFTR vacuum vessel: diamond wire cutting technology. In August 1999, this technology was successfully demonstrated and evaluated on vacuum vessel surrogates. Subsequently, the technology was improved and redesigned for the actual cutting of the vacuum vessel. Ten complete cuts were performed in a 6-month period to complete the removal of this unprecedented type of D&D (Decontamination and Decommissioning) activity
Modeling Algae Powered Neighborhood Through GIS and BIM Integration
This paper aims to propose a modeling method for algae powered neighborhoods through GIS-BIM integration. In the first part of the paper, the applicability of different types of algae systems in an urban neighborhood are studied. The various systems of algae provide different strengths and weakness that affect their performance and suitability for given urban scenarios. Through extensive literature review, the variables that affect the performance of the micro-algae in the built environment are identified, with a focus on flat-panel photo bio-reactors and tubular photobioreactors. A previous GIS model for data management, performance analysis and design of the algae systems is reviewed [1], which shows its limitations in managing fine-grained structures and functions of algae systems. A bottom-up BIM approach to deal with these limitations is further explored. The algae-embedded built environment can be modeled in the parametric 3D BIM and Rhinoceros with a set of building parameters for the roof, façade, window to wall ratio, etc. Subsequently, solar exposure on building surfaces, the use of the buildings and their respective façade types would be studied. Parametric 3D models of the buildings allows for faster design modification and the creation of multiple design options. These models can be used to perform energy analysis using the parametric energy analysis tool to check for building energy use intensity (EUI). The bottom-up approach explored in this research design aims to facilitate visualization and analysis of the built environment and gauge the productivity of microalgae. Finally, a platform for BIM –GIS integration and its possibility is explored in this paper. © 2017 The Authors
The long sunspot cycle 23 predicts a significant temperature decrease in cycle 24
Relations between the length of a sunspot cycle and the average temperature
in the same and the next cycle are calculated for a number of meteorological
stations in Norway and in the North Atlantic region. No significant trend is
found between the length of a cycle and the average temperature in the same
cycle, but a significant negative trend is found between the length of a cycle
and the temperature in the next cycle. This provides a tool to predict an
average temperature decrease of at least 1.0 "C from solar cycle 23 to 24 for
the stations and areas analyzed. We find for the Norwegian local stations
investigated that 25-56% of the temperature increase the last 150 years may be
attributed to the Sun. For 3 North Atlantic stations we get 63-72% solar
contribution. This points to the Atlantic currents as reinforcing a solar
signal.Comment: Accepted for publication in Journal of Atmospheric and
Solar-Terrestrial Physics February 9, 201
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The Innovations, Technology and Waste Management Approaches to Safely Package and Transport the World's First Radioactive Fusion Research Reactor for Burial
Original estimates stated that the amount of radioactive waste that will be generated during the dismantling of the Tokamak Fusion Test Reactor will approach two million kilograms with an associated volume of 2,500 cubic meters. The materials were activated by 14 MeV neutrons and were highly contaminated with tritium, which present unique challenges to maintain integrity during packaging and transportation. In addition, the majority of this material is stainless steel and copper structural metal that were specifically designed and manufactured for this one-of-a-kind fusion research reactor. This provided further complexity in planning and managing the waste. We will discuss the engineering concepts, innovative practices, and technologies that were utilized to size reduce, stabilize, and package the many unique and complex components of this reactor. This waste was packaged and shipped in many different configurations and methods according to the transportation regulations and disposal facility requirements. For this particular project, we were able to utilize two separate disposal facilities for burial. This paper will conclude with a complete summary of the actual results of the waste management costs, volumes, and best practices that were developed from this groundbreaking and successful project
bMagazine 2020
bMagazine is part annual report and part showcase of people thinking bigger and thinking differently about what's possible in communities across the Bush Foundation's region of Minnesota, North Dakota, South Dakota and the 23 Native nations that share that geography
Gene expression and microrna expression analysis in small arteries of spontaneously hypertensive rats. Evidence for er stress
Small arteries are known to develop functional and structural alterations in hypertension.
However, the mechanisms of this remodeling are not fully understood.We hypothesized
that altered gene expression is associated with the development of hypertension in mesenteric
arteries of spontaneously hypertensive rats (SHR). Three sublines of SHR and normotensive
Wistar Kyoto rats (WKY) were studied at 6 weeks and 5 months of age. MiRNA and
mRNA microarray experiments were performed and analyzed with bioinformatical tools,
including Ingenuity Pathway Analysis (IPA). Principal component analysis showed a clear
separation in both miRNA and mRNA expression levels between both ages studied, demonstrating
strong age-related changes in expression. At the miRNA level, IPA identified differences
between SHR and WKY related to metabolic diseases, cellular growth, and
proliferation. The mRNAs differentially expressed between SHR and WKY were related to
metabolism, cellular movement and proliferation. The most strongly upregulated gene (9.2-
fold) was thrombospondin 4 (Thbs4), a protein involved in the endoplasmic reticulum (ER)
stress response that activates transcription factor 6α (ATF6α). ATF6α downstream targets
were also differentially expressed in SHR vs. WKY. Differential expression of THBS4, the
cleaved form of ATF6α, and two of its targets were further confirmed at the protein level by
western blot. In summary, these data revealed a number of genes (n = 202) and miRNAs
(n = 3) in mesenteric arteries of SHR that had not been related to hypertension previously.
The most prominent of these, Thbs4, is related to vascular ER stress that is associated with
hypertensionThis work was supported by the European
Union, Marie Curie ITN number 606998 and 23571
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The First Decommissioning of a Fusion Reactor Fueled by Deuterium-Tritium
The Tokamak Fusion Test Reactor (TFTR) at the Plasma Physics Laboratory of Princeton University (PPPL) was the first fusion reactor fueled by a mixture of deuterium and tritium (D-T) to be decommissioned in the world. The decommissioning was performed over a period of three years and was completed safely, on schedule, and under budget. Provided is an overview of the project and detail of various factors which led to the success of the project. Discussion will cover management of the project, engineering planning before the project started and during the field work as it was being performed, training of workers in the field, the novel adaptation of tools from other industry, and the development of an innovative process for the use of diamond wire to segment the activated/contaminated vacuum vessel. The success of the TFTR decommissioning provides a viable model for the decommissioning of D-T burning fusion devices in the future
Efficacy of transoral fundoplication vs omeprazole for treatment of regurgitation in a randomized controlled trial.
Background
The aim of this randomized, crossover study was to determine if transoral fundoplication (TF) could further improve clinical outcomes in partial responders to high-dose (HD) proton-pump inhibitor (PPI) therapy and to evaluate durability of TF. Methods
In seven United States centers, patients with hiatal hernia ≤2 cm and abnormal esophageal acid exposure (EAE) were randomized to TF (n = 40) or HD PPIs (n = 23) group. At 6-month follow-up, PPI patients underwent crossover. We assessed clinical outcomes 6-month post TF in crossover patients (COP), as compared to 6-month of HD PPI therapy, and 12-month outcomes in patients initially randomized to TF. The primary outcome was symptom control evaluated by Reflux Disease Questionnaire and Reflux Symptom Index. Secondary outcomes included healing of esophagitis, normalization of EAE and PPI use after TF. We analyzed 21 COP and 39 TF patients. McNemar’s test or Fisher exact test was used to compare proportions. Results
Of 63 randomized patients, 3 were lost to follow-up, leaving 39 TF and 21 COP for analyses. In the COP, TF further improved control of regurgitation and of atypical symptoms achieved after six months of HD PPIs. Of 20 patients with GERD symptoms after six months of high-dose PPI therapy, 65% (13/20) reported global elimination of troublesome regurgitation and atypical symptoms post TF off PPIs; 67% (6/9) reported no troublesome regurgitation. Esophagitis further healed in 75% (6/8) of patients. Seventy-one percent of COP patients were off PPIs six months following TF. Normalization of EAE decreased from 52% after HD PPIs (on PPIs) to 33% after TF (off PPIs), p =0.388. In the original TF group, 12-month post TF, 77% of patients achieved complete symptom control, 82% ceased PPI therapy, 100% healed esophagitis and 45% normalized EAE. Conclusions
The results of this study indicate that in patients with incomplete symptom control on high-dose PPI therapy TF may provide further elimination of symptoms and esophagitis healing. In the original TF group, the clinical outcomes of TF remained stable between 6- and 12-month follow-up. Trial registration
Clinicaltrials.gov: NCT01647958
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