158 research outputs found
Sizing gold nanoparticles by optical extinction spectroscopy
The measurement of optical extinction is used to determine the size of nearly spherical gold nanoparticles suspended in solution, produced by a 'reverse micelles' process. The contrast between the maximum and the minimum in the extinction spectra around 450 and 520 nm shows a linear dependence with the mean radius of the gold particles less than 3 nm; however, the method can be used to size particles up to 7 nm. Experimental results for extinction spectra can be fitted by Mie's theory if the optical constants from bulk material values are modified by introducing the limitation of the mean free path due to collisions of conduction electrons with the boundary of the nanoparticles.Facultad de Ciencias ExactasCentro de Investigaciones Óptica
Sizing gold nanoparticles by optical extinction spectroscopy
The measurement of optical extinction is used to determine the size of nearly spherical gold nanoparticles suspended in solution, produced by a 'reverse micelles' process. The contrast between the maximum and the minimum in the extinction spectra around 450 and 520 nm shows a linear dependence with the mean radius of the gold particles less than 3 nm; however, the method can be used to size particles up to 7 nm. Experimental results for extinction spectra can be fitted by Mie's theory if the optical constants from bulk material values are modified by introducing the limitation of the mean free path due to collisions of conduction electrons with the boundary of the nanoparticles.Facultad de Ciencias ExactasCentro de Investigaciones Óptica
Second T = 3/2 state in B and the isobaric multiplet mass equation
Recent high-precision mass measurements and shell model calculations~[Phys.
Rev. Lett. {\bf 108}, 212501 (2012)] have challenged a longstanding explanation
for the requirement of a cubic isobaric multiplet mass equation for the lowest
isospin quartet. The conclusions relied upon the choice of the
excitation energy for the second state in B, which had two
conflicting measurements prior to this work. We remeasured the energy of the
state using the reaction and significantly disagree
with the most recent measurement. Our result supports the contention that
continuum coupling in the most proton-rich member of the quartet is not the
predominant reason for the large cubic term required for nuclei
PO-0875: Evaluation of a dedicated brain metastases planning algorithm for radiosurgery: a new treatment paradigm
Sizing gold nanoparticles by optical extinction spectroscopy
The measurement of optical extinction is used to determine the size of nearly spherical gold nanoparticles suspended in solution, produced by a 'reverse micelles' process. The contrast between the maximum and the minimum in the extinction spectra around 450 and 520 nm shows a linear dependence with the mean radius of the gold particles less than 3 nm; however, the method can be used to size particles up to 7 nm. Experimental results for extinction spectra can be fitted by Mie's theory if the optical constants from bulk material values are modified by introducing the limitation of the mean free path due to collisions of conduction electrons with the boundary of the nanoparticles.Facultad de Ciencias ExactasCentro de Investigaciones Óptica
Characterization of Large Volume 3.5 x 8 inches LaBr3:Ce Detectors
The properties of large volume cylindrical 3.5 x 8 inches (89 mm x 203 mm)
LaBr3:Ce scintillation detectors coupled to the Hamamatsu R10233-100SEL
photo-multiplier tube were investigated. These crystals are among the largest
ones ever produced and still need to be fully characterized to determine how
these detectors can be utilized and in which applications. We tested the
detectors using monochromatic gamma-ray sources and in-beam reactions producing
gamma rays up to 22.6 MeV; we acquired PMT signal pulses and calculated
detector energy resolution and response linearity as a function of gamma-ray
energy. Two different voltage dividers were coupled to the Hamamatsu
R10233-100SEL PMT: the Hamamatsu E1198-26, based on straightforward resistive
network design, and the LABRVD, specifically designed for our large volume
LaBr3:Ce scintillation detectors, which also includes active semiconductor
devices. Because of the extremely high light yield of LaBr3:Ce crystals we
observed that, depending on the choice of PMT, voltage divider and applied
voltage, some significant deviation from the ideally proportional response of
the detector and some pulse shape deformation appear. In addition, crystal
non-homogeneities and PMT gain drifts affect the (measured) energy resolution
especially in case of high-energy gamma rays. We also measured the time
resolution of detectors with different sizes (from 1x1 inches up to 3.5x8
inches), correlating the results with both the intrinsic properties of PMTs and
GEANT simulations of the scintillation light collection process. The detector
absolute full energy efficiency was measured and simulated up to gamma-rays of
30 Me
Prevalence and factors associated with chronic use of levothyroxine: A cohort study
Importance Levothyroxine prescriptions are rising worldwide. However, there are few data on factors associated with chronic use. Objective To assess the prevalence of chronic levothyroxine use, its rank among other chronic drugs and factors associated with chronic use. To assess the proportion of users outside the therapeutic range of thyroid-stimulating hormone (TSH). Design Cohort study (CoLaus|PsyCoLaus) with recruitment from 2003 to 2006. Follow-ups occurred 5 and 10 years after baseline. Participants A random sample of Lausanne (Switzerland) inhabitants aged 35-75 years. Main outcomes We evaluated the prevalence of chronic levothyroxine use and we then ranked it among the other most used chronic drugs. The ranking was compared to data from health insurance across the country. We assessed the association between each factor and chronic levothyroxine use in multivariable logistic regression models. The proportion of chronic levothyroxine users outside the usual TSH therapeutic range was assessed. Results 4,334 participants were included in the analysis (mean±SD age 62.8±10.4 years, 54.9% women). 166 (3.8%) participants were chronic levothyroxine users. Levothyroxine was the second most prescribed chronic drug after aspirin in the cohort (8.2%) and the third most prescribed when using Swiss-wide insurance data. In multivariable analysis, chronic levothyroxine use was associated with increasing age [odds ratio 1.03, 95% confidence interval 1.01-1.05 per 1-year increase]; female sex [11.87 (5.24-26.89)]; BMI [1.06 (1.02- 1.09) per 1-kg/m2 increase]; number of concomitant drugs [1.22 (1.16-1.29) per 1-drug increase]; and family history of thyroid pathologies [2.18 (1.37-3.48)]. Among chronic levothyroxine users with thyroid hormones assessment (n = 157), 42 (27%) were outside the TSH therapeutic range (17% overtreated and 10% undertreated). Conclusions In this population-based study, levothyroxine ranked second among chronic drugs. Age, female sex, BMI, number of drugs and family history of thyroid pathologies were associated with chronic levothyroxine use. More than one in four chronic users were over- or undertreated
ZrO2 phase structure in coating films and powders obtained by sol-gel process
Zirconia coating film and powder obtained by the sol-gel route using zirconium n-propoxide as starting material and acid catalyst were investigated by the Perturbed Angular Correlations method, X-Ray Diffraction and Differential Scanning Calorimetry and Differential Thermal Analyses. The hyperfine interaction, measured after annealing the samples at increasing temperatures up to 1100°C, allowed to distinguish five different zirconium neighborhoods. Two of them describe rather disordered material which, on heating, crystallizes to the tetragonal phase and end finally in monoclinic zirconia. As compared with the powder, the film exhibits a minor fraction of an unidentified ordered form and a higher and more stable fraction of tetragonal phase. In addition, the tetragonal to monoclinic conversion takes place at higher temperatures and with a larger activation energy.Facultad de Ciencias Exacta
Characterization of Large Volume 3.5″ x 8″ LaBr3:Ce Detectors for the HECTOR+ array
A selection of the properties of large volume, cylindrical 3.5" x 8" LaBr 3 :Ce scintillation detectors coupled to a 3.5" PMT (model R10233-1000SEL from HAMAMATSU) and a special designed Voltage Divider (LABRVD) will be discussed. A number of 10 of such detectors constitute the HECTOR + array which, in fall 2012, measured at GSI coupled to the AGATA DEMOSTRATOR at the PRESPEC experimental setup. These crystals are among the largest ever produced and needed to be characterized. We have performed several tests and here we discuss, in particular, the energy resolution measured using monochromatic γ −ray sources and in-beam reactions producing γ −rays up to 22.6 MeV. As already measured in two previous works a saturation in the energy resolution was observed in case of high energy gamma rays. Crystal non-homogeneities and PMT gain drifts can affect the resolution of measurements especially in case of high energy γ −rays
Characterization of the proposed 4-α cluster state candidate in O 16
The O16(α,α′) reaction was studied at θlab=0 at an incident energy of Elab=200 MeV using the K600 magnetic spectrometer at iThemba LABS. Proton decay and α decay from the natural parity states were observed in a large-acceptance silicon strip detector array at backward angles. The coincident charged-particle measurements were used to characterize the decay channels of the 06+ state in O16 located at Ex=15.097(5) MeV. This state is identified by several theoretical cluster calculations to be a good candidate for the 4-α cluster state. The results of this work suggest the presence of a previously unidentified resonance at Ex≈15 MeV that does not exhibit a 0+ character. This unresolved resonance may have contaminated previous observations of the 06+ state
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