In-Line Profile/Easy Open Inspection

Design, build, and test a device that has the capability of visually inspecting our zipper profiles on our production lines for start-ups or a device that can detect easy-open/weak zippers during regular production

2016 ASC Bidding Competition – Heavy Civil

We represent the 2016 Montana Tech Heavy Civil team. Our senior design project consisted of competing in the Region 6 ASC (Associated Schools of Construction) Heavy Civil Bidding Competition in Reno, Nevada. The competition required a full year of preparation. The Fall semester was dedicated to planning, practicing, and gathering resources, while the second semester involved traveling to Reno and performing in the competition. Our preparation involved performing practice bids where various aspects of heavy civil construction were studied. We also devoted a significant amount of time developing our presentation skills, and team building exercises were implemented to encourage unit cohesion. Industry professionals were consulted to enhance our knowledge base and give us new perspective on how to look at a project. Finally, our preparation culminated with a simulated competition where we estimated a project and presented our solution to a mock panel of judges. The competition involved a 16-hour time-frame where we developed our bid and solution for the given problem statement. We were then given 8 hours to prepare for a 20 minute presentation which was followed by a 10 minute Q&A session. Our efforts placed us 5th out of 12 teams

AKARI and IRAS: From beam corrections to SEDs

There is significant scientific value to be gained from combining AKARI fluxes with data at other far-infrared (IR) wavelengths from the Infrared Astronomical Satellite (IRAS) and Herschel missions. To be able to do this we must ensure that there are no systematic differences between the data sets that need to be corrected before the fluxes are compatible with each other. One such systematic effect identified in the Bright Source Catalog version 1 (BSCv1) data is the issue of beam corrections. We determine these for the BSC version 2 (BSCv2) data by correlating ratios of appropriate IRAS and AKARI bands with the difference in 2 Micron All Sky Survey (2MASS) J-band extended and point source magnitudes for sources cross-matched between the IRAS Faint Source Catalog (FSC), AKARI BSCv2 and 2MASS catalogs. We find significant correlations (p ≪ 10 −13) indicating that beam corrections are necessary in the 65 and 90 μm bands. We then use these corrected fluxes to supplement existing data in spectral energy distribution (SED) fits for ultraluminous infrared galaxies (ULIRGs) in the Herschel ULIRG Survey (HERUS). The addition of AKARI fluxes makes little difference to the results of simple (T, β) fits to the SEDs of these sources, though there is a general decrease in reduced χ2 values. The utility of the extra AKARI data, however, is in allowing physically more realistic SED models with more parameters to be fitted to the data. We also extend our analysis of beam correction issues in the AKARI data by examining the Herschel Reference Sample (HRS) galaxies, which have Herschel photometry from 100 to 500 μm and which are more spatially extended than the HERUS ULIRGs. 34 of the HRS sources have good Herschel SEDs and matching data from AKARI. This investigation finds that our simple 2MASS-based beam correction scheme is inadequate for these larger and more complex sources. There are also indications that additional beam corrections at 140 and 160 μm are needed for these sources, extended on scales >1′

Durrington Walls to West Amesbury by way of Stonehenge: a major transformation of the Holocene landscape

A new sequence of Holocene landscape change has been discovered through an investigation of sediment sequences, palaeosols, pollen and molluscan data discovered during the Stonehenge Riverside Project. The early post-glacial vegetational succession in the Avon valley at Durrington Walls was apparently slow and partial, with intermittent woodland modification and the opening-up of this landscape in the later Mesolithic and earlier Neolithic, though a strong element of pine lingered into the third millennium BC. There appears to have been a major hiatus around 2900 cal BC, coincident with the beginnings of demonstrable human activities at Durrington Walls, but slightly after activity started at Stonehenge. This was reflected in episodic increases in channel sedimentation and tree and shrub clearance, leading to a more open downland, with greater indications of anthropogenic activity, and an increasingly wet floodplain with sedges and alder along the river’s edge. Nonetheless, a localized woodland cover remained in the vicinity of DurringtonWalls throughout the third and second millennia BC, perhaps on the higher parts of the downs, while stable grassland, with rendzina soils, predominated on the downland slopes, and alder–hazel carr woodland and sedges continued to fringe the wet floodplain. This evidence is strongly indicative of a stable and managed landscape in Neolithic and Bronze Age times. It is not until c 800–500 cal BC that this landscape was completely cleared, except for the marshy-sedge fringe of the floodplain, and that colluvial sedimentation began in earnest associated with increased arable agriculture, a situation that continued through Roman and historic times

Point centromeres contain more than a single centromere-specific Cse4 (CENP-A) nucleosome

Quantitative measurement of the number of Cse4, CBF3, and Ndc80 proteins at kinetochores reveals a 2.5–3-fold increased copy number relative to prior estimates

Engaging Citizen Scientists to Keep Transit Times Fresh and Ensure the Efficient Use of Transiting Exoplanet Characterization Missions

This white paper advocates for the creation of a community-wide program to maintain precise mid-transit times of exoplanets that would likely be targeted by future platforms. Given the sheer number of targets that will require careful monitoring between now and the launch of the next generation of exoplanet characterization missions, this network will initially be devised as a citizen science project -- focused on the numerous amateur astronomers, small universities and community colleges and high schools that have access to modest sized telescopes and off-the-shelf CCDs.Comment: White Paper submitted to Astro2020 Science Call, 5 pages, 3 figures, community comments and involvement are welcome

Risk of major cardiovascular events in patients with psoriasis receiving biologic therapies: a prospective cohort study

Background: The cardiovascular safety profile of biologic therapies used for psoriasis is unclear. Objectives: To compare the risk of major cardiovascular events (CVEs; acute coronary syndrome, unstable angina, myocardial infarction and stroke) in patients with chronic plaque psoriasis treated with adalimumab, etanercept or ustekinumab in a large prospective cohort. Methods: Prospective cohort study examining the comparative risk of major CVEs was conducted using the British Association of Dermatologists Biologics and Immunomodulators Register. The main analysis compared adults with chronic plaque psoriasis receiving ustekinumab with tumour necrosis‐α inhibitors (TNFi: etanercept and adalimumab), whilst the secondary analyses compared ustekinumab, etanercept or methotrexate against adalimumab. Hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using overlap weights by propensity score to balance baseline covariates among comparison groups. Results: We included 5468 biologic‐naïve patients subsequently exposed (951 ustekinumab; 1313 etanercept; and 3204 adalimumab) in the main analysis. The secondary analyses also included 2189 patients receiving methotrexate. The median (p25–p75) follow‐up times for patients using ustekinumab, TNFi, adalimumab, etanercept and methotrexate were as follows: 2.01 (1.16–3.21), 1.93 (1.05–3.34), 1.94 (1.09–3.32), 1.92 (0.93–3.45) and 1.43 (0.84–2.53) years, respectively. Ustekinumab, TNFi, adalimumab, etanercept and methotrexate groups had 7, 29, 23, 6 and 9 patients experiencing major CVEs, respectively. No differences in the risk of major CVEs were observed between biologic therapies [adjusted HR for ustekinumab vs. TNFi: 0.96 (95% CI 0.41–2.22); ustekinumab vs. adalimumab: 0.81 (0.30–2.17); etanercept vs. adalimumab: 0.81 (0.28–2.30)] and methotrexate against adalimumab [1.05 (0.34–3.28)]. Conclusions: In this large prospective cohort study, we found no significant differences in the risk of major CVEs between three different biologic therapies and methotrexate. Additional studies, with longer term follow‐up, are needed to investigate the potential effects of biologic therapies on incidence of major CVEs

The Primary PE and School Sport Premium

Central to London’s successful bid to host the 2012 Olympic and Paralympic Games, was the Government’s commitment to improve competitive sport and the sporting habits of young people (Ofsted, 2014). On the 12th March 2013, the then Prime Minister, David Cameron, announced that Primary Schools in England would receive funding worth £150 million per year to create a sustainable infrastructure for long-lasting change and improve the provision of physical education (PE) and sport across all state maintained primary schools. Speaking at the time, he said: ‘We can create a culture in our schools that encourages all children to be active and enjoy sport.’ He added: ‘The Olympic and Paralympic Games marked an incredible year for this country and I will always be proud that we showed the world what Britain can do. I want to ensure the Games count for the future too and that means capitalising on the inspiration young people took from what they saw during those summer months.’: https://www.bbc.co.uk/sport/21808982 Six years on, and with a total investment now of over £1.2 billion, the Primary PE and Sport Premium (here onwards referred to as the PESS Premium) has been a defining feature of the London 2012 legacy. Invariably funding streams at this level do not last forever or in the same format, which raises significant questions about what impact the funding has had on young people since 2013. We believe that a significant investment from Government merits debate and accountability at the highest possible level and that it should acknowledge where the opportunities and shortcomings of such a policy have left us. During the years of austerity, mounting concerns have arisen over the present and long term state of children’s health and the need for the debate to be heard is now imperative. To date there has been little critical appraisal of the PESS Premium funding. This report aims to begin a necessary process and in doing so, brings together evidence from across the sector to consider the future of the PESS Premium post 2018. During the course of the report, we outline and underpin the holistic value and importance of PE for every child. We examine the historic status and funding of PE and Sport and the nature and increasing diversity of the workforce. How has the PESS Premium funding impacted the way in which the subject is regarded and the ability of those tasked with delivering it to discharge their responsibilities? We have uncovered an abiding uncertainty about the nature of the PESS Premium itself; the ways in which it may be spent and its effect on an increasing divide between PE specialists, generalists and externally contracted coaches. Will its legacy be to have established a secure foundation for lifelong physical activity, sport and education – or is it, in effect, another temporarily seductive mirage, leaving PE precisely where it has become accustomed to be; regularly sidelined, delivered largely by those who are not qualified teachers and perpetuating the status quo for the children who already belong to groups that are perceived to be at a disadvantage? The PESS Premium funding is a significant sum and these questions deserve answers. This report is therefore our contribution to an essential debate, containing practical suggestions that we hope will be of use to policy makers. We invite all who care about the physical and mental health and emotional wellbeing of children to join the discussion