113 research outputs found

    Are EHEA assessment systems really different from traditional ones? An empirical analysis of academic performance in an accounting subject

    Get PDF
    Este trabajo analiza los determinantes del rendimiento académico, medidos como la probabilidad de aprobar la asignatura o el examen final, a partir de las puntuaciones obtenidas en las distintas actividades de evaluación continua. Para ello se emplean los datos de una asignatura de contabilidad financiera y se cuantifican los factores determinantes del rendimiento del alumnado mediante modelos logit y probit. El ánimo es ver si el nuevo sistema de evaluación impuesto en el EEES aumenta el rendimiento del alumnado. Los resultados revelan que, en general, las notas de las actividades de evaluación continua son determinantes estadísticamente significativos del rendimiento, si bien su impacto varía en función del criterio analizado.The objective of this research is to explore the determinants of academic performance, measured as the probability of passing the course or the final exam, from the grades on the various ongoing evaluation activities. Specifically, this research uses data from a financial accounting course to identify and quantify determinants of student performance through logit and probit models. The focus is to see if the new evaluation system (European Higher Education Area, EHEA) increases student performance. The results show that, in general, the grades of continuous activities are statistically significant determinants of performance, although its impact varies depending on the criteria analyzed

    Does “black shales” suffice for lithological changes in transgressive facies? The case of the Agua de la Mula Member (Agrio Formation), Neuquen Basin, Argentina

    Get PDF
    “Black shales” ¿Es suficiente para denotar cambios litológicos en facies transgresivas? Caso del Miembro Agua de la Mula (Formación Agrio), Cuenca Neuquina, Argentina Se estudió, por medio de microscopía óptica y electrónica de barrido, así como por difracción de rayos X y contenido de carbono orgánico, la variabilidad de litofacies correspondiente a la etapa transgresiva basal del Miembro Agua de la Mula de la Formación Agrio, a escala de cuenca. Se pudieron diferenciar tres grupos de sedimentitas de grano fino: (i) un grupo dominados por componentes intracuencales derivados de la producción orgánica y carbonática, (ii) otro con altos porcentajes de componentes terrígenos y (iii) un tercer grupo con predominio de minerales autigénicos. Además de procesos de baja energía, como el de decantación a partir de material en suspensión, se documentaron corrientes tractivas, desarrollo de matas microbianas y bioturbación. Los procesos sedimentarios reconocidos sugieren que durante la depositación los escenarios fueron dinámicos y variables a distintas escalas, tanto en sentido lateral como vertical, y no relativamente estables como antes se presumía

    Análisis sedimentológico de facies de rampa externa: la Formación Agrio (Cretácico inferior), en el sector central de la Cuenca Neuquina, Argentina

    Get PDF
    Microfacies of distal marine deposits of the Lower Cretaceous Agrio Formation – Pilmatué and Agua de la Mula members – in the Neuquén basin has been analyzed taken into account field data, whole-rock phase-minerals and clay mineralogy with X-ray diffraction, organic components and optical and electron microscopy. Depositional and diagenetic fabrics are compared for the lowermost part of both members. Two facies associations were distinguished that correspond to two depositional settings: distal outer ramp (FA-1); and, proximal outer ramp (FA-2). FA-1 is composed of sediments mainly deposited by suspension settling with calcareous microfossils partially preserved as fecal pellets and organo-minerallic aggregates related to high bioproductivity in the water column. Conversely, FA-2 is dominated by extrabasinal components with illite-rich clay- to silt-si - zed particle aggregates. Storm-influenced processes have a main role in sediment transportation and accumulation as well as controlling oxygenation pulses of the bottom waters. In addition, burial diagenesis was evaluated taking into account thermal maturity of organics together with diagenetic textures such as growth of authigenic minerals and mechanical and chemical compaction features. Due to clay mineral assemblages are mainly detrital in origin the possible effects of burial diagenesis on them cannot be directly evaluated

    A bio-inspired hypoxia sensor using HIF1a-oxygen-dependent degradation domain

    Get PDF
    Functional imaging has become an important tool in oncology because it not only provides information about the size and localization of the tumour, but also about the pathophysiological features of the tumoural cells. One of the characteristic features of some tumour types is that their fast growth leads to defcient intratumoral vascularization, which results in low oxygen availability. To overcome this lack of oxygen, tumoural cells activate the neoangiogenic program by upregulating the transcription factor HIF-1α. Herein we report a non-invasive in vitro detection method of hypoxia using designed fuorescent peptide probes based on the oxygen-dependent degradation domain of HIF-1α. The fuorescent probe retains the oxygen-sensing capability of HIF-1α, so that it is stabilized under hypoxia and readily degraded by the proteasome under normoxia, thus providing direct information of the cellular oxygen availabilityThis work has received financial support from the Spanish MICINN (SAF2009-08629; J.A.C.) and ISCIII, MINECO (PI15/01129), AEI/FEDER, UE (CTQ2017-89166-R; E.P.), the Consellería de Cultura, Educación e Ordenación Universitaria (GPC2014/030, INCITE08PXIB208091PR; J.A.C.), the Xunta de Galicia (Centro Singular de Investigación de Galicia accreditations 2016‐2019, ED431G/05 and ED431G/09) and the European Regional Development Fund (ERDF). C.P. thanks the Spanish MICINN for her PhD fellowship. E.P. thanks the UDC-Inditex InTalent Programme for her research contract and fundingS

    “Carillas sin desgaste dentario”

    Get PDF
    En el presente trabajo se describe la técnica de rehabilitación sobre un paciente que asiste a la consulta con una demanda urgente de estética en el sector antero superior manifestando su deseo de mejorar la forma y color de sus dientes. En la actualidad los pacientes están demandando procedimientos conservadores, que sean el tratamiento de corta duración, con el mínimo de dolor y con excelentes resultados estéticos. Por este motivo se opto como opción las carillas de porcelana feldespáticas, ya que tienen una estructura micro cristalina, donde los cristales tienen una distribución uniforme, reforzada con cristales de leucita. Esta porcelana puede ser fabricada con 0,2 mm de espesor aproximadamente como el espesor de una lente de contacto. La gran ventaja de este tipo de porcelana es el echo de que se pueden fabricar carillas de gran dureza en un espesor menor. Todas las ventajas que nos proporciona este tipo de carillas es que determinaron su uso en este caso clínico.Facultad de Odontologí

    Determination of Partition Coefficients of Selected Model Migrants between Polyethylene and Polypropylene and Nanocomposite Polypropylene

    Get PDF
    Studies on nanoparticles have focused the attention of the researchers because they can produce nanocomposites that exhibit unexpected hybrid properties. Polymeric materials are commonly used in food packaging, but from the standpoint of food safety, one of the main concerns on the use of these materials is the potential migration of low molecular substances from the packaging into the food. The key parameters of this phenomenon are the diffusion and partition coefficients. Studies on migration from food packaging with nanomaterials are very scarce. This study is focused on the determination of partition coefficients of different model migrants between the low-density polyethylene (LDPE) and polypropylene (PP) and between LDPE and nanocomposite polypropylene (naPP). The results show that the incorporation of nanoparticles in polypropylene increases the mass transport of model migrants from LDPE to naPP. This quantity of migrants absorbed into PP and naPP depends partially on the nature of the polymer and slightly on the chemical features of the migrant. Relation () between partition coefficient and partition coefficient at 60°C and 80°C shows that only BHT at 60°C has a less than 1. On the other hand, bisphenol A has the highest with approximately 50 times more.The study was financially supported by the Xunta de Galicia (Project no. INCITE08PXIB203096). R. Sendon is grateful to the “Parga Pondal” Program financed by “Consellería de Innovación e Industria, Xunta de Galicia” for her postdoctoral contractS

    Detección automática de tejido blando nasal en CT-Scan y MRI utilizando Random Forests

    Get PDF
    Este trabajo presenta un procedimiento sencillo para la detección automática de tejido blando nasal a partir de imágenes médicas de tipo CT-Scan y MRI. Para dichas imágenes, inicialmente se aplica un procedimiento de segmentación manual y técnicas de procesamiento digital de imágenes para la confección de un dataset de entrenamiento, conteniendo los valores de cada pixel de la imagen por un lado y 4 valores que representan el área de interés a detectar por otro. Posteriormente, se utilizan métodos de preprocesamiento de datos sobre estas imágenes para ser utilizadas como conjunto de entrenamiento, validación y prueba de un estimador, empleando un algoritmo basado en un modelo de regresión multi-salida denominado Random Forest. Este último es capaz de detectar automáticamente el área de la imagen en la cual se encuentra el tejido blando nasal prediciendo simultáneamente los 4 valores que representan los bordes del área de interés mencionada.Sociedad Argentina de Informática e Investigación Operativ

    Solar Thermal Collector Output Temperature Prediction by Hybrid Intelligent Model for Smartgrid and Smartbuildings Applications and Optimization

    Get PDF
    Currently, there is great interest in reducing the consumption of fossil fuels (and other non-renewable energy sources) in order to preserve the environment; smart buildings are commonly proposed for this purpose as they are capable of producing their own energy and using it optimally. However, at times, solar energy is not able to supply the energy demand fully; it is mandatory to know the quantity of energy needed to optimize the system. This research focuses on the prediction of output temperature from a solar thermal collector. The aim is to measure solar thermal energy and optimize the energy system of a house (or building). The dataset used in this research has been taken from a real installation in a bio-climate house located on the Sotavento Experimental Wind Farm, in north-west Spain. A hybrid intelligent model has been developed by combining clustering and regression methods such as neural networks, polynomial regression, and support vector machines. The main findings show that, by dividing the dataset into small clusters on the basis of similarity in behavior, it is possible to create more accurate models. Moreover, combining different regression methods for each cluster provides better results than when a global model of the whole dataset is used. In temperature prediction, mean absolute error was lower than 4 ∘ C.info:eu-repo/semantics/publishedVersio

    Blockade of the SNARE Protein Syntaxin 1 Inhibits Glioblastoma Tumor Growth

    Get PDF
    Glioblastoma (GBM) is the most prevalent adult brain tumor, with virtually no cure, and with a median overall survival of 15 months from diagnosis despite of the treatment. SNARE proteins mediate membrane fusion events in cells and are essential for many cellular processes including exocytosis and neurotransmission, intracellular trafficking and cell migration. Here we show that the blockade of the SNARE protein Syntaxin 1 (Stx1) function impairs GBM cell proliferation. We show that Stx1 loss-of-function in GBM cells, through ShRNA lentiviral transduction, a Stx1 dominant negative and botulinum toxins, dramatically reduces the growth of GBM after grafting U373 cells into the brain of immune compromised mice. Interestingly, Stx1 role on GBM progression may not be restricted just to cell proliferation since the blockade of Stx1 also reduces in vitro GBM cell invasiveness suggesting a role in several processes relevant for tumor progression. Altogether, our findings indicate that the blockade of SNARE proteins may represent a novel therapeutic tool against GB
    corecore