36 research outputs found
Chromosomal and genic mechanisms of reproductive isolation: the case of Suncus murinus
Exact solution of the six-vertex model with domain wall boundary conditions. Antiferroelectric phase
We obtain the large asymptotics of the partition function of the
six-vertex model with domain wall boundary conditions in the antiferroelectric
phase region, with the weights a=\sinh(\ga-t), b=\sinh(\ga+t), c=\sinh(2\ga),
|t|<\ga. We prove the conjecture of Zinn-Justin, that as ,
Z_n=C\th_4(n\om) F^{n^2}[1+O(n^{-1})], where \om and are given by
explicit expressions in \ga and , and is the Jacobi theta
function. The proof is based on the Riemann-Hilbert approach to the large
asymptotic expansion of the underlying discrete orthogonal polynomials and on
the Deift-Zhou nonlinear steepest descent method.Comment: 69 pages, 10 figure
Deep inelastic inclusive and diffractive scattering at values from 25 to 320 GeV with the ZEUS forward plug calorimeter
Deep inelastic scattering and its diffractive component, , have been studied at HERA with the ZEUS
detector using an integrated luminosity of 52.4 pb. The method has
been used to extract the diffractive contribution. A wide range in the
centre-of-mass energy (37 -- 245 GeV), photon virtuality (20 -- 450
GeV) and mass (0.28 -- 35 GeV) is covered. The diffractive cross
section for GeV rises strongly with , the rise becoming
steeper as increases. The data are also presented in terms of the
diffractive structure function, , of the proton. For fixed
and fixed , \xpom F^{\rm D(3)}_2 shows a strong rise as \xpom \to
0, where \xpom is the fraction of the proton momentum carried by the
Pomeron. For Bjorken-, \xpom F^{\rm D(3)}_2 shows
positive scaling violations, while for
negative scaling violations are observed. The diffractive structure function is
compatible with being leading twist. The data show that Regge factorisation is
broken.Comment: 89 pages, 27 figure
The hypothetical Old-Northern chromosome race of Sorex araneus found in the Ural Mts.
Available from JSOR at https://www.jstor.org/stable/23735690Chromosomes of two populations of the common shrew, Sorex araneus L. (Mammalia, Insectivora, Soricidae), from the northern Ural Mts. were investigated. In both sites, homozygous, all-metacentric autosomal complements were revealed, with the autosomal arm combinations af, bc, go, hn, ip, jl, km, qr, tu. This karyotype is identical to that predicted by Halkka et al. (1994) as the hypothetical Old-Northern race connecting the northern and eastern ratial groups of Sorex araneus in Eurasia.This study was supported by grants from the INTAS (No. 93-1463), Russian Foundation of Fundamental Research (No. 95-04-12698a), and Grant Agency of the Academy of Sciences of the Czech Republic (No. A6045601)
Recombination Map of the Common Shrew, Sorex araneus (Eulipotyphla, Mammalia)
The Eurasian common shrew (Sorex araneus L.) is characterized by spectacular chromosomal variation, both autosomal variation of the Robertsonian type and an XX/XY1Y2 system of sex determination. It is an important mammalian model of chromosomal and genome evolution as it is one of the few species with a complete genome sequence. Here we generate a high-precision cytological recombination map for the species, the third such map produced in mammals, following those for humans and house mice. We prepared synaptonemal complex (SC) spreads of meiotic chromosomes from 638 spermatocytes of 22 males of nine different Robertsonian karyotypes, identifying each autosome arm by differential DAPI staining. Altogether we mapped 13,983 recombination sites along 7095 individual autosomes, using immunolocalization of MLH1, a mismatch repair protein marking recombination sites. We estimated the total recombination length of the shrew genome as 1145 cM. The majority of bivalents showed a high recombination frequency near the telomeres and a low frequency near the centromeres. The distances between MLH1 foci were consistent with crossover interference both within chromosome arms and across the centromere in metacentric bivalents. The pattern of recombination along a chromosome arm was a function of its length, interference, and centromere and telomere effects. The specific DNA sequence must also be important because chromosome arms of the same length differed substantially in their recombination pattern. These features of recombination show great similarity with humans and mice and suggest generality among mammals. However, contrary to a widespread perception, the metacentric bivalent tu usually lacked an MLH1 focus on one of its chromosome arms, arguing against a minimum requirement of one chiasma per chromosome arm for correct segregation. With regard to autosomal chromosomal variation, the chromosomes showing Robertsonian polymorphism display MLH1 foci that become increasingly distal when comparing acrocentric homozygotes, heterozygotes, and metacentric homozygotes. Within the sex trivalent XY1Y2, the autosomal part of the complex behaves similarly to other autosomes
Chromosome Synapsis and Recombination in Male Hybrids between Two Chromosome Races of the Common Shrew (Sorex araneus L., Soricidae, Eulipotyphla)
Hybrid zones between chromosome races of the common shrew (Sorex araneus) provide exceptional models to study the potential role of chromosome rearrangements in the initial steps of speciation. The Novosibirsk and Tomsk races differ by a series of Robertsonian fusions with monobrachial homology. They form a narrow hybrid zone and generate hybrids with both simple (chain of three chromosomes) and complex (chain of eight or nine) synaptic configurations. Using immunolocalisation of the meiotic proteins, we examined chromosome pairing and recombination in males from the hybrid zone. Homozygotes and simple heterozygotes for Robertsonian fusions showed a low frequency of synaptic aberrations (<10%). The carriers of complex synaptic configurations showed multiple pairing abnormalities, which might lead to reduced fertility. The recombination frequency in the proximal regions of most chromosomes of all karyotypes was much lower than in the other regions. The strong suppression of recombination in the pericentromeric regions and co-segregation of race specific chromosomes involved in the long chains would be expected to lead to linkage disequilibrium between genes located there. Genic differentiation, together with the high frequency of pairing aberrations in male carriers of the long chains, might contribute to maintenance of the narrow hybrid zone
Chromosome Synapsis and Recombination in Male Hybrids between Two Chromosome Races of the Common Shrew (Sorex araneus L., Soricidae, Eulipotyphla)
Spatial organization of fibroblast and spermatocyte nuclei with different B chromosome content in Korean field mouse Apodemus peninsulae (Rodentia, Muridae)
Korean field mouse (Apodemus peninsulae) shows a wide variation in the number of B chromosomes composed of constitutive heterochromatin. For this reason, it provides a good model to study the influence of the number of centromeres and amount of heterochromatin on spatial organization of interphase nuclei. We analyzed the three-dimensional organization of fibroblast and spermatocyte nuclei of the field mice carrying different number of B chromosomes using laser scanning microscopy and 3D fluorescence in situ hybridization. We detected a co-localization of the B chromosomes with constitutive heterochromatin of the chromosomes of the basic set. We showed not random distribution of B chromosomes in the spermatocyte nuclei. Unpaired B chromosomes showed tendency to occur in the compartment formed by unpaired part of XY-bivalent.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
Germline-restricted chromosome (GRC) in the sand martin and the pale martin (Hirundinidae, Aves): synapsis, recombination and copy number variation
All songbirds studied to date have an additional Germline Restricted Chromosome (GRC), which is no