Algumas considerações sobre a mortalidade infantil em São Paulo

A mortalidade infantil ascende na capital de S. Paulo e no interior a algarismos que pedem meditação. Uma das causas do phenomeno está no apparelho official de hygiene infantil. de acção extremamente limitada e só exercida em diminuta proporção na capital do Estado e que justifica o sempre alto e constante coefficiente lethal

Serviço de Estatistica sanitaria

A primeira exigencia de um bom serviço de ·estatística sanitaria é naturalmente um perfeito recenseamento geral da população; o censo do povo é a necessidade basica ou preliminar de todos os trabalhos desta natureza, que a simples conjecturas se reduzem, quando lhes falte esse elemento essencial, semelhantemente a syllogismos em que sejam vacillantes as premissas maiores

Suggestões para a melhoria da Legistação Sanitaria Estadual, sobre generos alimenticios

A questão da alimentação publica constitue capitulo importante de hygiene e merece de todas as administrações cuidadosa attenção. Envolve attribuiçôes que, segundo os paizes e suas organízaçôcs po1itícas, devem ser perfeitamente definidas para melhor e maior rendimento de serviço. É necessarío prever e evitar conflictos entre as autoridades, crear e intensificar a cooperação effíciente entre os varios poderes e agentes da segurança sanitaria

Observation of environment-induced double sudden transitions in geometric quantum correlations

Correlations in quantum systems exhibit a rich phenomenology under the effect of various sources of noise. We investigate theoretically and experimentally the dynamics of quantum correlations and their classical counterparts in two nuclear magnetic resonance setups, as measured by geometric quantifiers based on trace-norm. We consider two-qubit systems prepared in Bell diagonal states, and perform the experiments in decohering environments resulting from Bell diagonal-preserving Markovian local noise. We then report the first observation of environment-induced double sudden transitions in the geometric quantum correlations, a genuinely nonclassical effect not observable in classical correlations. The evolution of classical correlations in our physical implementation reveals in turn the finite-time relaxation to a pointer basis under nondissipative decoherence, which we characterize geometrically in full analogy with predictions based on entropic measures.Comment: 5 pages, 2 figures. v2: Minor corrections. Published versio

Poder calorífico de algumas substâncias alimentares da cozinha paulista

Apresentamos neste trabalho os primeiros resultados de experiências de nutriição, que sob vários aspectos encetamos no Instituto de Higiene

Suppression of the hemolytic effect of mesoporous silica nanoparticles after protein corona interaction: independence of the surface microchemical environment

Mesoporous silica nanoparticles are known to induce the hemolysis of human red blood cells (RBCs) when citotoxicity assays are performed in a phosphate buffer solution (PBS). However, in a more realistic approach, the presence of blood plasma biomolecules must be considered in any nanotoxicological evaluation of porous SiO2 nanoparticles when biomedical applications through intravenous administration are aimed. In this context, it is demonstrated in this work that porous silica nanoparticles do not induce any cytotoxic effect on RBCs when hemolysis assay is done in the presence of blood plasma, regardless the surface charge (positive or negative) of the nanoparticle. The absence of hemolysis is mainly associated with the adsorption of plasma proteins on the nanoparticle surface, which leads to the formation of a stable protein coating (called protein corona or PC) that shields the original microchemical environment of bare nanoparticles.Nanopartículas mesoporosas de sílica são conhecidas por induzirem hemólise de células vermelhas do sangue (RBCs) humano quando ensaios de citotoxicidade são feitos em solução-tampão de fosfato (PBS). Entretanto, em uma abordagem mais realista, a presença de biomoléculas do plasma sanguíneo precisa ser considerada em qualquer avaliação nanotoxicológica de nanopartículas porosas de SiO2 quando se objetiva a sua utilização em aplicações biomédicas através de administração intravenosa. Nesse contexto, demonstrou-se neste trabalho que nanopartículas porosas de sílica não induzem nenhum efeito citotóxico em células vermelhas do sangue quando ensaios de hemólise são feitos na presença de plasma sanguíneo, independentemente da carga superficial (positiva ou negativa) da nanopartícula. A ausência de hemólise está principalmente associada à adsorção de proteínas do plasma sobre a superfície das nanopartículas, levando à formação de um recobrimento proteico estável (denominado protein corona ou PC) que blinda o ambiente microquímico original das nanopartículas.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual de Campinas Instituto de Química Laboratório de Química do Estado SólidoUniversidade Federal de São Paulo (UNIFESP) Departamento de BioquímicaUniversidade Federal do Ceará Departamento de FísicaUNIFESP, Depto. de BioquímicaSciEL

In Vitro Wound Healing Improvement By Low-level Laser Therapy Application In Cultured Gingival Fibroblasts.

The aim of this study was to determine adequate energy doses using specific parameters of LLLT to produce biostimulatory effects on human gingival fibroblast culture. Cells (3 × 10(4) cells/cm(2)) were seeded on 24-well acrylic plates using plain DMEM supplemented with 10% fetal bovine serum. After 48-hour incubation with 5% CO(2) at 37°C, cells were irradiated with a InGaAsP diode laser prototype (LASERTable; 780 ± 3 nm; 40 mW) with energy doses of 0.5, 1.5, 3, 5, and 7 J/cm(2). Cells were irradiated every 24 h totalizing 3 applications. Twenty-four hours after the last irradiation, cell metabolism was evaluated by the MTT assay and the two most effective doses (0.5 and 3 J/cm(2)) were selected to evaluate the cell number (trypan blue assay) and the cell migration capacity (wound healing assay; transwell migration assay). Data were analyzed by the Kruskal-Wallis and Mann-Whitney nonparametric tests with statistical significance of 5%. Irradiation of the fibroblasts with 0.5 and 3 J/cm(2) resulted in significant increase in cell metabolism compared with the nonrradiated group (P < 0.05). Both energy doses promoted significant increase in the cell number as well as in cell migration (P < 0.05). These results demonstrate that, under the tested conditions, LLLT promoted biostimulation of fibroblasts in vitro.201271945

New segregates from the Neotropical genus Stryphnodendron (Leguminosae, Caesalpinioideae, mimosoid clade)

Non-monophyly is a prominent issue in mimosoid legumes, even in some of the less speciose genera such as the neotropical genus Stryphnodendron. This genus includes 35 species occurring from Nicaragua to Southern Brazil mostly in humid forests and savannas. Previous taxonomic studies of Stryphnodendron have highlighted morphologically distinct groups within the genus, recognized by differences on leaves (number of pinnae and size of leaflets), inflorescences (a simple or compound thyrse), and fruit types (legume, nucoid legume or follicle). Recent phylogenetic analyses have confirmed the non-monophyly of Stryphnodendron, supporting the recognition of three independent and morphologically well-delimited genera. Here we re-circumscribe Stryphnodendron and propose the two new genera Gwilymia and Naiadendron. In addition, we also provide an updated taxonomic account of the closely related genus Microlobius, including the proposal of a lectotype for the single species in the genus

Au+Au central collisions at 150, 250 and 400 AMeV energies in QMD with relativistic forces

An extensive comparison of the recent experimental data published by the FOPI collaboration at GSI with the results of a relativistically covariant formulation of a QMD code is presented. For most of the quantities we find agreement with the experimental results showing that the derived force has a reasonable momentum dependence.Comment: 33 pages with 18 EPSF figures included. Final version to appear in Nucl. Phys.