44 research outputs found
Supplementary material to: Long-term efficacy of T3 analogue Triac in children and adults with MCT8 deficiency: a real-life retrospective cohort study
- Author
- Akker E.L.T. (Erica) van den
- Bacos I. (Iuliu)
- Barca D. (Diana)
- Berg S.A.A. (Sjoerd) van den
- Bertini E. (Enrico)
- Brunetti-Pierri N. (Nicola)
- Brunner D. (Doris)
- Cappa M. (Marco)
- Cappuccio G. (Gerarda)
- Chatterjee K. (Krishna)
- Chesover A.D. (Alexander)
- Christian P. (Peter)
- Coutant R. (Régis)
- Craiu D. (Dana)
- Crock P. (Patricia)
- Dewey C. (Cheyenne)
- Dica A. (Alice)
- Dimitri P. (Paul)
- Dubey R. (Rachana)
- Enderli A. (Anina)
- Fairchild J. (Jan)
- Gallichan J. (Jonathan)
- Garibaldi L.R. (Luigi)
- Geest F.S. (Ferdy) van
- George B. (Belinda)
- Groeneweg S. (Stefan)
- Hackenberg A. (Annette)
- Heinrich B. (Bianka)
- Huynh Tony (T.)
- Klosowska A. (Anna)
- Lawson-Yuen A. (Amy)
- Linder-Lucht M. (Michaela)
- Lyons G. (Greta)
- Monti Lora F. (Felipe)
- Moran C. (Carla)
- Müller K. (Katalin)
- Paone L. (Laura)
- Paul P.G. (Praveen)
- Peeters R.P. (Robin)
- Polak M. (Michel)
- Porta F. (Francesco)
- Reinauer C. (Christina)
- Rijke Y.B. (Yolanda) de
- Seckold R. (Rowen)
- Seven Menevse T. (Tuba)
- Simm P. (Peter)
- Simon A. (Anna)
- Spada M. (Marco)
- Stoupa A. (Athanasia)
- Szeifert L. (Lilla)
- Tonduti D. (Davide)
- Toor H. (Hans) van
- Turan S. (Serap)
- Vanderniet J. (Joel)
- Visser W.E. (Edward)
- Waart M. (Monique) de
- Wal R. (Ronald) van der
- Walt A. (Adri) van der
- Wermeskerken A-M. (Anne-Marie) van
- Wierzba J. (Jolanta)
- Zibordi F. (Federica)
- Zung A. (Amnon)
- Publication venue
- Publication date
- 03/09/2021
- Field of study
Multi-trait genome-wide association study identifies new loci associated with optic disc parameters
- Author
- Allingham R.R. (R Rand)
- Amin N. (Najaf)
- Aslam T. (Tariq)
- Atan D. (Denize)
- Aung T. (Tin)
- Bailey J.C. (Jessica Cooke)
- Barman S.A. (Sarah A.)
- Barrett J.H. (Jennifer H.)
- Bishop P.N. (Paul)
- Blows P. (Peter)
- Bonnemaijer P.W.M. (Pieter)
- Boutin T.S. (Thibaud S.)
- Budenz D.L. (Donald L.)
- Bunce C. (Catey)
- Burdon K.P. (Kathryn P.)
- Carare R.O. (Roxana O.)
- Chakravarthy U. (Usha)
- Chan M. (Michelle)
- Cheng C.-Y. (Ching-Yu)
- Chua S.Y.L. (Sharon Y. L.)
- Crabb D.P. (David)
- Craig J.E. (Jamie)
- Cree A.J. (Angela)
- Cumberland P.M. (Philippa M.)
- Dan Gore ()
- Day A. (Alexander)
- Desai P. (Parul)
- Dhillon B. (Bal)
- Dick A.D. (Andrew D.)
- Duijn C.M. (Cornelia) van
- Egan C. (Cathy)
- Ennis S. (Sarah)
- Fingert J. (John)
- Foster P.J. (Paul)
- Fruttiger M. (Marcus)
- Gaasterland D. (Douglas)
- Gaasterland T. (Terry)
- Gallacher J.E.J. (John E. J.)
- Garway D.F. (David F.)
- Gerhold-Ay A. (Aslihan)
- Gharahkhani P. (Puya)
- Gibson J. (Jane)
- Guggenheim J. (Jean)
- Haines J.L. (Jonathan)
- Hammond C.J. (Christopher)
- Hardcastle A. (Alison)
- Harding S.P. (Simon)
- Hark L. (Lisa)
- Hauser M.A. (Michael)
- Hayward C. (Caroline)
- Hewit A.W. (Alex)
- Hogg R. (Ruth)
- Hysi P.G. (Pirro G.)
- Höhn R. (René)
- Iglesias A.I. (Adriana I.)
- Igo Jr. R.P. (Robert)
- Jonas J.B.
- Kang J.H. (Jae Hee)
- Keane P.A. (Pearse A.)
- Khaw P.T. (Peng T.)
- Khawaja A.P. (Anthony)
- Khor C.-C. (Chiea-Cheun)
- Khor C.C.
- Klaver C.C.W. (Caroline)
- Kraft P. (Peter)
- Lascaratos G. (Gerassimos)
- Lee R.K. (Richard K.)
- Leeuwen E.M. (Elisabeth M. van)
- Lichter P.A. (Paul A.)
- Liu Y. (Yutao)
- Lotery A.J. (Andrew)
- Macgillivray T. (Tom)
- MacGregor S. (Stuart)
- Mackey D.A. (David)
- Mackie S. (Sarah)
- Martin K. (Keith)
- McGaughey M. (Michelle)
- McGuinness B. (Bernadette)
- McKay G.J. (Gareth)
- McKibbin M. (Martin)
- Mishra A. (Aniket)
- Mitchell P. (Paul)
- Mitry D. (Danny)
- Moore T. (Tony)
- Morgan J.E. (James E.)
- Moroi S. (Syoko)
- Muthy Z.A. (Zaynah A.)
- Nickels S. (Stefan)
- Owen C.G. (Chris G.)
- O’Sullivan E. (Eoin)
- Pang C.P. (Chi Pui)
- Pasquale L.R. (Louis R)
- Pasquale L.R. (Louis)
- Pasutto F. (Francesca)
- Patel P. (Praveen)
- Paterson E. (Euan)
- Pericak M. (Margaret)
- Peto T. (Tünde)
- Petzold A. (Axel)
- Polasek O. (Ozren)
- Rahi J.S. (Jugnoo S.)
- Realini A. (Anthony)
- Rhee D. (Doug)
- Richards J.R. (Julia R.)
- Ritch R. (Robert)
- Rudnikca A.R. (Alicja R.)
- Scott W.K. (William)
- Self J. (Jay)
- Simcoe M. (Mark)
- Singh K. (Kuldev)
- Sit A.J. (Arthur J.)
- Sivaprasad S.
- Springelkamp H. (Henriët)
- Steel D. (David)
- Stratton I. (Irene)
- Strouthidis N. (Nicholas)
- Sudlow C. (Cathie)
- Thiadens A.A.H.J. (Alberta)
- Thomas D. (Dhanes)
- Thorleifsson G. (Gudmar)
- Thorsteinsdottir U. (Unnur)
- Trucco E. (Emanuele)
- Tufail A. (Adnan)
- Vernon S.A. (Stephen A.)
- Viswanathan A.C. (Ananth C.)
- Viswanathan A.C. (Ananth C.)
- Vitart V. (Veronique)
- Vollrath D. (Douglas)
- Weinreb R.N. (Robert N.)
- Wiggs J.L. (Janey L.)
- Williams C. (Cathy)
- Williams K.M. (Katie M.)
- Wilmer D.Z. (Don Zack)
- Wilson J.F. (James)
- Wojciechowski R. (Robert)
- Wollstein G. (Gadi)
- Wong T.Y. (Tien Yin)
- Woodside J.V. (J.)
- Yates M.M. (Max M.)
- Yip J. (Jennifer)
- Young T.L. (Terrri L)
- Zeller T. (Tanja)
- Zheng Y. (Yalin)
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/12/2019
- Field of study
A new avenue of mining published genome-wide association studies includes the joint analysis of related traits. The power of this approach depends on the genetic correlation of traits, which reflects the number of pleiotropic loci, i.e. genetic loci influencing multiple traits. Here, we applied new meta-analyses of optic nerve head (ONH) related traits implicated in primary open-angle glaucoma (POAG); intraocular pressure and central corneal thickness using Haplotype reference consortium imputations. We performed a multi-trait analysis of ONH parameters cup area, disc area and vertical cup-disc ratio. We uncover new variants; rs11158547 in PPP1R36-PLEKHG3 and rs1028727 near SERPINE3 at genome-wide significance that replicate in independent Asian cohorts imputed to 1000 Genomes. At this point, validation of these variants in POAG cohorts is hampered by the high degree of heterogeneity. Our results show that multi-trait analysis is a valid approach to identify novel pleiotropic variants for ONH
Open data from the third observing run of LIGO, Virgo, KAGRA, and GEO
- Author
- Abbott R.
- Abe H.
- Acernese F.
- Ackley K.
- Adhicary S.
- Adhikari N.
- Adhikari R.X.
- Adkins V.K.
- Adya V.B.
- Affeldt C.
- Agarwal D.
- Agathos M.
- Aguiar O.D.
- Aiello L.
- Ain A.
- Ajith P.
- Akutsu T.
- Al-Jodah A.
- Albanesi S.
- Alfaidi R.A.
- Allocca A.
- Alléné C.
- Almualla M.
- Altin P.A.
- Amato A.
- Amez-Droz L.
- Amorosi A.
- Anand S.
- Ananyeva A.
- Andersen R.
- Anderson S.B.
- Anderson W.G.
- Andia M.
- Ando M.
- Andrade T.
- Andres N.
- Andrić T.
- Andrés-Carcasona M.
- Ansoldi S.
- Antelis J.M.
- Antier S.
- Aoumi M.
- Apostolatos T.
- Appavuravther E.Z.
- Appert S.
- Apple S.K.
- Arai K.
- Araya A.
- Araya M.C.
- Areeda J.S.
- Aritomi N.
- Arnaud N.
- Arogeti M.
- Aronson S.M.
- Arun K.G.
- Arène M.
- Asada H.
- Ashton G.
- Aso Y.
- Assiduo M.
- Assis de Souza Melo S.
- Aston S.M.
- Astone P.
- Aubin F.
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- Babak S.
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- Badger C.
- Bae S.
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- Bai Y.
- Baier J.G.
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- Bajpai R.
- Baka T.
- Ball M.
- Ballardin G.
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- Weller R.A.
- Wellmann F.
- Wen L.
- Wette K.
- Weßels P.
- Whelan J.T.
- White D.D.
- Whiting B.F.
- Whittle C.
- Wilk O.S.
- Wilken D.
- Willetts K.
- Williams D.
- Williams M.J.
- Williamson A.R.
- Willis J.L.
- Willke B.
- Wipf C.C.
- Woan G.
- Woehler J.
- Wofford J.K.
- Wong D.
- Wong H.T.
- Wong I.C.F.
- Wright M.
- Wu C.
- Wu D.S.
- Wu H.
- Wysocki D.M.
- Xiao L.
- Xu V.A.
- Yadav N.
- Yamada T.
- Yamamoto H.
- Yamamoto K.
- Yamamoto M.
- Yamamoto T.
- Yamamoto T.S.
- Yamashita K.
- Yamazaki R.
- Yang F.W.
- Yang K.Z.
- Yang Y.-C.
- Yap M.J.
- Yeeles D.W.
- Yelikar A.B.
- Yeung T.Y.
- Yokoyama J.
- Yokozawa T.
- Yoo J.
- Yu Hang
- Yu Haocun
- Yuzurihara H.
- Zadrożny A.
- Zannelli A.J.
- Zanolin M.
- Zeeshan M.
- Zeidler S.
- Zelenova T.
- Zendri J.-P.
- Zevin M.
- Zhang J.
- Zhang L.
- Zhang R.
- Zhang T.
- Zhang Y.
- Zhao C.
- Zhao Yue
- Zhao Yuhang
- Zheng Y.
- Zhong H.
- Zhou R.
- Zhu X.J.
- Zhu Z.-H.
- Zimmerman A.B.
- Zucker M.E.
- Zweizig J.
- Publication venue
- American Astronomical Society
- Publication date
- 01/01/2023
- Field of study
The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://gwosc.org. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages
Global variation in postoperative mortality and complications after cancer surgery: a multicentre, prospective cohort study in 82 countries
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
- Achkasov Sergey
- Acosta Eric
- Adamo Karin
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- Adams Jamie
- Adams Lawrence
- Adawi Samer
- Adebanjo Ademola
- Adel Marina
- Adel Sawsan
- Ademuyiwa Adesoji
- Ademuyiwa Adesoji
- Adenuga Adedire
- Aderounmu Adewale
- Adesanya Opeoluwa
- Adesina Alaba
- Adesunkanmi Abdul-Rashid
- Adeyeye Ademola
- Adidharma Peter
- Adisa Adewale O
- Adnan Nour
- Afifi Amr Abdelghani
- Afifi Eman
- Afolayan Michael Olatunji
- Afzal Asma
- Agarwal Arnav
- Agarwal Raksheeth
- Agbakwuru Augustine
- Agbeko Anita Eseenam
- Aguilar Martinez Maria Del Mar
- Aguilera Maria Lorena
- Aguilera-Arevalo Maria-Lorena
- Ahlqvist Sandra
- Ahmad Izzuddin Ahmad Imran
- Ahmad Kasim
- Ahmad Sarwat
- Ahmed Ahmedgaber
- Ahmed Hazem Abdelkarem
- Ahmed Mariam
- Ahmed Nabila
- Ahmed Zahra
- Ainoa Eppu
- Aithie Joanna M S
- Ajani Costanza
- Ajao Akinlabi
- Ajiboye Anthony
- Ajmera Ankit
- Akande Oluwatosin
- Akaydin Elif
- Akbaba Ata Cem
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- Akin Alp
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- Al Nassrallah Majdi
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- Al Saqqa Sara
- Al-Allaf Omar
- Al-Busaidi Ibrahim S.
- Al-Dhufri Ali
- Al-Himyari Hamza S.
- Al-Masri Mahmoud
- Al-Najjar Hani
- Al-Sabbagh Yusra
- Al-Shwaikh Samar
- Al-Slaibi Ibrahim
- Al-Taher Raed
- Al-Tammam Hiba
- Alabuzidi Aya
- Alagha Othman
- Alammarin Mohammad
- Alapatt John
- Alasttal Mohammed
- Alatise Olusegun Isaac
- Albaggar Marwa
- Albahnasawi Moath A.
- Albati Naif
- Alberga Anna
- Alberts Justin
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- Ali Ahmad Syed Mustafa
- Ali SANI Samuel
- Ali Amr
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- Aliosin Oleg
- Aliyu Halima
- Aljaafreh Almoutuz
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- Almasri Murad
- Almeida Braga Sara
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- Amandito Radhian
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- Bogusevicius Algirdas
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- Elshafei Houssein
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- Elshawy Mohamed Elemam
- Elsherbeny Mohammed Yasser
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- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
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- Etonyeaku Amarachukwu
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- Fahmawee Toqa
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- Falato Armando
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- Ye Geoffrey
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- Zabiyaka Mikhail
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- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Šatkauskas Mindaugas
- Škimelyte Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 30/01/2021
- Field of study
© 2021 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 licenseBackground: 80% of individuals with cancer will require a surgical procedure, yet little comparative data exist on early outcomes in low-income and middle-income countries (LMICs). We compared postoperative outcomes in breast, colorectal, and gastric cancer surgery in hospitals worldwide, focusing on the effect of disease stage and complications on postoperative mortality. Methods: This was a multicentre, international prospective cohort study of consecutive adult patients undergoing surgery for primary breast, colorectal, or gastric cancer requiring a skin incision done under general or neuraxial anaesthesia. The primary outcome was death or major complication within 30 days of surgery. Multilevel logistic regression determined relationships within three-level nested models of patients within hospitals and countries. Hospital-level infrastructure effects were explored with three-way mediation analyses. This study was registered with ClinicalTrials.gov, NCT03471494. Findings: Between April 1, 2018, and Jan 31, 2019, we enrolled 15 958 patients from 428 hospitals in 82 countries (high income 9106 patients, 31 countries; upper-middle income 2721 patients, 23 countries; or lower-middle income 4131 patients, 28 countries). Patients in LMICs presented with more advanced disease compared with patients in high-income countries. 30-day mortality was higher for gastric cancer in low-income or lower-middle-income countries (adjusted odds ratio 3·72, 95% CI 1·70–8·16) and for colorectal cancer in low-income or lower-middle-income countries (4·59, 2·39–8·80) and upper-middle-income countries (2·06, 1·11–3·83). No difference in 30-day mortality was seen in breast cancer. The proportion of patients who died after a major complication was greatest in low-income or lower-middle-income countries (6·15, 3·26–11·59) and upper-middle-income countries (3·89, 2·08–7·29). Postoperative death after complications was partly explained by patient factors (60%) and partly by hospital or country (40%). The absence of consistently available postoperative care facilities was associated with seven to 10 more deaths per 100 major complications in LMICs. Cancer stage alone explained little of the early variation in mortality or postoperative complications. Interpretation: Higher levels of mortality after cancer surgery in LMICs was not fully explained by later presentation of disease. The capacity to rescue patients from surgical complications is a tangible opportunity for meaningful intervention. Early death after cancer surgery might be reduced by policies focusing on strengthening perioperative care systems to detect and intervene in common complications. Funding: National Institute for Health Research Global Health Research Unit
Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study
- Author
- A Yacoub Mina
- A. Adam Mohammed
- A. Nassar Mahmoud
- A.Nemer Ayoob
- Aahlin Eirik Kjus
- Ab Rahim Mohd Fadliyazid
- Abad Gurumeta Alfredo
- Abad-Motos Ane
- Abang Jamari Dyg Zahratul Hamrak
- Abantanga Francis
- Abarca Sol
- Abazid Eias
- Abbas Abbas
- Abbas Khalid
- Abbas Mohammad Monir
- Abbasy Jibran
- Abbosh Ali
- Abd Karim Muhammad Fairuz Shah
- Abd Wahab Haidar Hadri
- Abd Barook
- Abdalei Abdulwahab
- Abdalla Ahmed Elkamel Ahmed
- Abdallah Aya
- AbdAllah Mostafa Salim Mohamed
- Abdel Malik Abu Baker
- Abdelhady Mousa Heba
- Abdelhady Samar
- Abdelhakim Ahmed
- Abdelkader Muhammad
- Abdelkawy Shaza
- Abdelkhalek Mohamed
- Abdellatif Esraa
- Abdelmaksoud Tawakel Noura
- Abdelmohsen Naglaa
- Abdelmotaleb Ibrahem
- Abdelrazek Aly
- Abdelsalam Israa
- Abdelshakour Mahmoud
- Abdelwahed Ahmed Mohamed
- Abdou Abdulrahman Osama
- Abdou Alrawy
- Abdou Hossam
- Abdul Aziz Mohamed Rezal
- Abdul Aziz Nora
- Abdulgawad Almogy Mariam
- Abdulla Mazin A.
- Abdullah Muhammad Tariq
- Abdullahi Lawal
- Abdullayev Seymur
- Abed Saeed
- Abelló David
- Abiola Olajide
- Abo mahadi Asmaa'
- Abo-khammash Areej
- Abou Chaar Mohamad K.
- Abou El.soud Moustafa Ramadan
- Abouelsoad Nervana
- Abraham Joyner
- Abreu da Silva Alberto
- Abu Ahammala Ayman B.
- Abu Al Amrain Mahmoud
- Abu Al-saleem Hasan
- Abu Alamrain Abdulwhhab
- Abu Alqumboz Amjad
- Abu Ataya Ahmed
- Abu hallalah Muad fathi khalleefah
- Abu Jamie Najlaa
- Abu Jayyab Israa
- Abu shua'ib Rana
- Abu Zainah Baraa
- Abu-Nimeh Samar
- Abu-Rous Mohammed R.
- Abu-srour Abrar
- Abuelhatal Hasan
- Abuelqomboz Ayham
- Abuhilal Baseel
- Abuhlaiga Ma'aly
- Abujamra Saleh
- Abukhalaf Sadi A.
- Abusalem Lana
- AbuSirrees Mahmoud
- Acevedo Veronica
- Acharya Rajgopal
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- Dollie Qaasim
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- Dominguez Joaquina
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- Eldoseuky mohammed Amany
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- Elewaily Mohamed Ibrahim Elsayed
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- Essam Ibrahim El Desouki Muhammad Ahmed Muhammad
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- Ghellai Ali M.
- Ghonaim Mennatullah
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- Gnintedeme Olivier Tchianze
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- Wong Hsu Ven
- Wong Jane J
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- Wong Lai Fen
- Wong Michael Pak-Kai
- Wong Sui-Weng
- Wong Tsz Lun Ernest
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- Woon-Shoo-Tong Xiao-Ming Sarah
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- Yüksel Osman
- Zabiyaka Mikhail
- Zachariah Sanoop Koshy
- Zafar Syed Nabeel
- Zaffaroni Gloria
- Zahra Baryab
- Zahran Diaaaldin
- Zakaria Andee Dzulkarnaen
- Zakaria Mai
- Zakaria Omar
- Zakaria Zaidi
- Zambrana Campos Vanesa
- Zammit Matthew
- Zanini Nicola
- Zara Vlu Jean
- Zarti Heba
- Zarzycki Piotr
- Zattoni Davide
- Zavala Gabriela
- Zawahrah Hassan
- Zeiton Asaid
- Zeko Amanda
- Zeng Zhi
- Zeromskas Paulius
- Zhang Geoffrey
- Zhivkov Evgeni
- Zid Esraa
- Zidan Ahmed Mohy
- Zielasek Christian
- Zilinskas Justas
- Zimmermann Bernd
- Ziprin Paul
- Zizzo Maurizio
- Zografos George
- Zoikas Athanasios
- Zorrilla Matilla Laura Patricia
- Zoulamoglou Menelaos
- Zreeg Dafer
- Zub-Pokrowiecka Anna
- Zubiaurre Vanessa
- Zuhdy Mohammed
- Zuikyte Diana
- Zuloaga Fernandez del Valle Carlos Jose
- Zulu Stanley
- Ângelo Miguel
- Älgå Andreas
- Çolak Elif
- Ümarik Toomas
- Čepuliené Daiva
- Şahin Can
- Šatkauskas Mindaugas
- Škimelytè Monika
- Šlenfuktas Vygintas
- Šuman Oliver
- Žatecký Jan
- Žumbakys Žygimantas
- Župan Domagoj
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/07/2022
- Field of study
© 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licenseBackground: Early death after cancer surgery is higher in low-income and middle-income countries (LMICs) compared with in high-income countries, yet the impact of facility characteristics on early postoperative outcomes is unknown. The aim of this study was to examine the association between hospital infrastructure, resource availability, and processes on early outcomes after cancer surgery worldwide. Methods: A multimethods analysis was performed as part of the GlobalSurg 3 study—a multicentre, international, prospective cohort study of patients who had surgery for breast, colorectal, or gastric cancer. The primary outcomes were 30-day mortality and 30-day major complication rates. Potentially beneficial hospital facilities were identified by variable selection to select those associated with 30-day mortality. Adjusted outcomes were determined using generalised estimating equations to account for patient characteristics and country-income group, with population stratification by hospital. Findings: Between April 1, 2018, and April 23, 2019, facility-level data were collected for 9685 patients across 238 hospitals in 66 countries (91 hospitals in 20 high-income countries; 57 hospitals in 19 upper-middle-income countries; and 90 hospitals in 27 low-income to lower-middle-income countries). The availability of five hospital facilities was inversely associated with mortality: ultrasound, CT scanner, critical care unit, opioid analgesia, and oncologist. After adjustment for case-mix and country income group, hospitals with three or fewer of these facilities (62 hospitals, 1294 patients) had higher mortality compared with those with four or five (adjusted odds ratio [OR] 3·85 [95% CI 2·58–5·75]; p<0·0001), with excess mortality predominantly explained by a limited capacity to rescue following the development of major complications (63·0% vs 82·7%; OR 0·35 [0·23–0·53]; p<0·0001). Across LMICs, improvements in hospital facilities would prevent one to three deaths for every 100 patients undergoing surgery for cancer. Interpretation: Hospitals with higher levels of infrastructure and resources have better outcomes after cancer surgery, independent of country income. Without urgent strengthening of hospital infrastructure and resources, the reductions in cancer-associated mortality associated with improved access will not be realised. Funding: National Institute for Health and Care Research
Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
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- Yadav N
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- Yarbrough Z
- Yeh S.-W
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- Yeung S.M.C
- Yin X
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- Yokozawa T
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- Yu H
- Yuzurihara H
- Zadrożny A
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- Zeeshan M
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- Zhao Yuhang
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- Zimmerman A.B
- Zucker M.E
- Zweizig J
- Publication venue
- HAL CCSD
- Publication date
- 10/09/2024
- Field of study
International audienceWe present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search includes 636 GW candidates received in low latency, 86 of which have been confirmed by the offline analysis and included in the third cumulative Gravitational-Wave Transient Catalogs (GWTC-3). Targeted searches were carried out on the entire GW sample using the maximum--likelihood NITRATES pipeline on the BAT data made available via the GUANO infrastructure. We do not detect any significant electromagnetic emission that is temporally and spatially coincident with any of the GW candidates. We report flux upper limits in the 15-350 keV band as a function of sky position for all the catalog candidates. For GW candidates where the Swift-BAT false alarm rate is less than 10−3 Hz, we compute the GW--BAT joint false alarm rate. Finally, the derived Swift-BAT upper limits are used to infer constraints on the putative electromagnetic emission associated with binary black hole mergers
Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
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- Zeeshan M
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- Zimmerman A.B
- Zucker M.E
- Zweizig J
- Publication venue
- HAL CCSD
- Publication date
- 10/09/2024
- Field of study
International audienceWe present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search includes 636 GW candidates received in low latency, 86 of which have been confirmed by the offline analysis and included in the third cumulative Gravitational-Wave Transient Catalogs (GWTC-3). Targeted searches were carried out on the entire GW sample using the maximum--likelihood NITRATES pipeline on the BAT data made available via the GUANO infrastructure. We do not detect any significant electromagnetic emission that is temporally and spatially coincident with any of the GW candidates. We report flux upper limits in the 15-350 keV band as a function of sky position for all the catalog candidates. For GW candidates where the Swift-BAT false alarm rate is less than 10−3 Hz, we compute the GW--BAT joint false alarm rate. Finally, the derived Swift-BAT upper limits are used to infer constraints on the putative electromagnetic emission associated with binary black hole mergers
Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
- Author
- Abac A.G
- Abbott R
- Abe H
- Abouelfettouh I
- Acernese F
- Ackley K
- Adamcewicz C
- Adhicary S
- Adhikari N
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- Ambrosi Elena
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- Arellano F.E. Peña
- Argianas L. Granda
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- Aronson S.M
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- Barthelmy S.D
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- Bartos I
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- Benedetto V
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- Benoit W
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- Bernardini Maria Grazia
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- Yadav N
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- Yarbrough Z
- Yeh S.-W
- Yelikar A.B
- Yeung S.M.C
- Yin X
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- Yokozawa T
- Yoo J
- Yu H
- Yuzurihara H
- Zadrożny A
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- Zeeshan M
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- Zhao Yuhang
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- Zhu Z.-H
- Zimmerman A.B
- Zucker M.E
- Zweizig J
- Publication venue
- HAL CCSD
- Publication date
- 10/09/2024
- Field of study
International audienceWe present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search includes 636 GW candidates received in low latency, 86 of which have been confirmed by the offline analysis and included in the third cumulative Gravitational-Wave Transient Catalogs (GWTC-3). Targeted searches were carried out on the entire GW sample using the maximum--likelihood NITRATES pipeline on the BAT data made available via the GUANO infrastructure. We do not detect any significant electromagnetic emission that is temporally and spatially coincident with any of the GW candidates. We report flux upper limits in the 15-350 keV band as a function of sky position for all the catalog candidates. For GW candidates where the Swift-BAT false alarm rate is less than 10−3 Hz, we compute the GW--BAT joint false alarm rate. Finally, the derived Swift-BAT upper limits are used to infer constraints on the putative electromagnetic emission associated with binary black hole mergers
Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
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- Xiao L
- Xu V.A
- Xu Y
- Yaala M. Ben
- Yadav N
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- Yamamoto K
- Yamamoto M
- Yamamoto T
- Yamamoto T.S
- Yamamura S
- Yamazaki R
- Yan S
- Yan T
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- Yang K.Z
- Yang L.-C
- Yang Y
- Yarbrough Z
- Yeh S.-W
- Yelikar A.B
- Yeung S.M.C
- Yin X
- Yokoyama J
- Yokozawa T
- Yoo J
- Yu H
- Yuzurihara H
- Zadrożny A
- Zannelli A.J
- Zanolin M
- Zeeshan M
- Zelenova T
- Zendri J.-P
- Zeoli M
- Zerrad M
- Zevin M
- Zhang A.C
- Zhang J
- Zhang L
- Zhang R
- Zhang T
- Zhang Y
- Zhao C
- Zhao Yue
- Zhao Yuhang
- Zheng Y
- Zhong H
- Zhong S
- Zhou R
- Zhu Z.-H
- Zimmerman A.B
- Zucker M.E
- Zweizig J
- Publication venue
- HAL CCSD
- Publication date
- 10/09/2024
- Field of study
International audienceWe present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search includes 636 GW candidates received in low latency, 86 of which have been confirmed by the offline analysis and included in the third cumulative Gravitational-Wave Transient Catalogs (GWTC-3). Targeted searches were carried out on the entire GW sample using the maximum--likelihood NITRATES pipeline on the BAT data made available via the GUANO infrastructure. We do not detect any significant electromagnetic emission that is temporally and spatially coincident with any of the GW candidates. We report flux upper limits in the 15-350 keV band as a function of sky position for all the catalog candidates. For GW candidates where the Swift-BAT false alarm rate is less than 10−3 Hz, we compute the GW--BAT joint false alarm rate. Finally, the derived Swift-BAT upper limits are used to infer constraints on the putative electromagnetic emission associated with binary black hole mergers
Swift-BAT GUANO follow-up of gravitational-wave triggers in the third LIGO-Virgo-KAGRA observing run
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- Yuzurihara H
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- Zeeshan M
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- Zimmerman A.B
- Zucker M.E
- Zweizig J
- Publication venue
- HAL CCSD
- Publication date
- 10/09/2024
- Field of study
International audienceWe present results from a search for X-ray/gamma-ray counterparts of gravitational-wave (GW) candidates from the third observing run (O3) of the LIGO-Virgo-KAGRA (LVK) network using the Swift Burst Alert Telescope (Swift-BAT). The search includes 636 GW candidates received in low latency, 86 of which have been confirmed by the offline analysis and included in the third cumulative Gravitational-Wave Transient Catalogs (GWTC-3). Targeted searches were carried out on the entire GW sample using the maximum--likelihood NITRATES pipeline on the BAT data made available via the GUANO infrastructure. We do not detect any significant electromagnetic emission that is temporally and spatially coincident with any of the GW candidates. We report flux upper limits in the 15-350 keV band as a function of sky position for all the catalog candidates. For GW candidates where the Swift-BAT false alarm rate is less than 10−3 Hz, we compute the GW--BAT joint false alarm rate. Finally, the derived Swift-BAT upper limits are used to infer constraints on the putative electromagnetic emission associated with binary black hole mergers