Is it all in the eye of the beholder? The importance of situation construal for situational judgment test performance

German Research Foundatio

The importance of situation construal for situational judgment test performance

Recent research challenges the importance of situation descriptions for situational judgment test (SJT) performance. This study contributes to resolving the ongoing debate on whether SJTs are situational measures, by incorporating findings on person × situation interactions into SJT research. Specifically, across three studies (NTotal = 1,239), we first tested whether situation construal (i.e., the individual perception of situations in SJTs) predicts responses to SJT items. Second, we assessed whether the relevance of situation construal for SJT performance depends on test elements (i.e., situation descriptions and response options) and item features (i.e., description‐dependent vs. description‐independent SJT items). Lastly, we determined whether situation construal has incremental validity for job‐related criteria over and above SJT performance. The results showed that, for most SJT items, situation construal significantly contributed to SJT performance, even if only response options were available. This was also true for SJT items that are significantly more difficult to solve when situation descriptions are omitted (i.e., description‐dependent SJT items). Finally, situation construal explained variance in relevant criteria over and above SJT performance. Despite recent efforts to reconceptualize SJTs, our results suggest that they can still be viewed as situational measures. However, situation descriptions may be less crucial for these underlying situational processes. Theoretical and practical implications are discussed

Effects of situation descriptions on the construct-related validity of construct-driven situational judgment tests

All data and code are available on the Open Science Framework https://osf.io/py6cm/</p

Domain-specific greed

Greed, the insatiable and excessive desire and striving for more even at the expense of others, may be directed toward various goods. In this article, we propose that greed may be conceptualized as a domain-specific construct. Based on a literature review and an expert survey, we identified 10 domains of greed which we operationalized with the DOmain-SPEcific Greed (DOSPEG) questionnaire. In Study 1 (N = 725), we found support for the proposed structure and convergent validity with related constructs. Bifactor-(S-1) models revealed that generic greed is differentially related to the greed domains, indicating that generic greed primarily captures a striving for money and material things. In the second study (N = 591), we found that greed domains had incremental validity beyond generic greed with regard to corresponding criteria assessed via self- and other-reports. We conclude that greed can be conceptualized as a domain-specific construct and propose an onion model reflecting this structure

The R1441C mutation alters the folding properties of the ROC domain of LRRK2

LRRK2 is a 250 kDa multidomain protein, mutations in which cause familial Parkinson's disease. Previously, we have demonstrated that the R1441C mutation in the ROC domain decreases GTPase activity. Here we show that the R1441C alters the folding properties of the ROC domain, lowering its thermodynamic stability. Similar to small GTPases, binding of different guanosine nucleotides alters the stability of the ROC domain, suggesting that there is an alteration in conformation dependent on GDP or GTP occupying the active site. GTP/GDP bound state also alters the self-interaction of the ROC domain, accentuating the impact of the R1441C mutation on this property. These data suggest a mechanism whereby the R1441C mutation can reduce the GTPase activity of LRRK2, and highlights the possibility of targeting the stability of the ROC domain as a therapeutic avenue in LRRK2 disease

The Rio Grande Rise and Jean Charcot Seamount Chain - microcontinents or the trail of the Tristan-Gough hotspot? Cruise No. MSM 82, 18 March 2019 - 24 April 2019, Montevideo (Uruguay) - Montevideo (Uruguay), RIOGRANDE

Rio Grande Rise: microcontinent, mantle plume, or both? The origin of the Rio Grande Rise (RGR) is debated. It could represent a continental sliver, or a large igneous province that was emplaced in the late Cretaceous after the opening of the South Atlantic Ocean. The interplay between the RGR and the nearby Jean Charcot Seamount Chain (JCSC) is also not understood. Cruise MSM82 dredge sampled rocks from the JCSC and the RGR and measured two seismic refraction profiles across the RGR where it is bisected by a long rift graben. A range of geophysical data were also collected during much of the expedition, including magnetics, gravity, bathymetry (Kongsberg EM 122), sub-bottom profiling (ATLAS PARASOUND DS P70) and ADCP data. The combination of geochronological, geochemical and geophysical information will provide a unique window on the relation between mantle plumes, continental fragments and the evolution of large igneous provinces

Using Multiparametric Cardiac Magnetic Resonance to Phenotype and Differentiate Biopsy-Proven Chronic from Healed Myocarditis and Dilated Cardiomyopathy.

(1) Objectives: To discriminate biopsy-proven myocarditis (chronic vs. healed myocarditis) and to differentiate from dilated cardiomyopathy (DCM) using cardiac magnetic resonance (CMR). (2) Methods: A total of 259 consecutive patients (age 51 ± 15 years; 28% female) who underwent both endomyocardial biopsy (EMB) and CMR in the years 2008-2021 were evaluated. According to right-ventricular EMB results, patients were divided into either chronic (n = 130, 50%) or healed lymphocytic myocarditis (n = 60, 23%) or DCM (n = 69, 27%). The CMR protocol included functional, strain, and late gadolinium enhancement (LGE) imaging, T2w imaging, and T2 mapping. (3) Results: Left-ventricular ejection fraction (LV-EF) was higher, and the indexed end-diastolic volume (EDV) was lower in myocarditis patients (chronic: 42%, median 96 mL/m²; healed: 49%, 86 mL/m²) compared to the DCM patients (31%, 120 mL/m²), p &lt; 0.0001. Strain analysis demonstrated lower contractility in DCM patients vs. myocarditis patients, p &lt; 0.0001. Myocarditis patients demonstrated a higher LGE prevalence (68% chronic; 59% healed) than the DCM patients (45%), p = 0.01. Chronic myocarditis patients showed a higher myocardial edema prevalence and ratio (59%, median 1.3) than healed myocarditis (23%, 1.3) and DCM patients (13%, 1.0), p &lt; 0.0001. T2 mapping revealed elevated values more frequently in chronic (90%) than in healed (21%) myocarditis and DCM (23%), p &lt; 0.0001. T2 mapping yielded an AUC of 0.89 (sensitivity 90%, specificity 76%) in the discrimination of chronic from healed myocarditis and an AUC of 0.92 (sensitivity 86%, specificity 91%) in the discrimination of chronic myocarditis from DCM, both p &lt; 0.0001. (4) Conclusions: Multiparametric CMR imaging, including functional parameters, LGE and T2 mapping, may allow differentiation of chronic from healed myocarditis and DCM and therefore help to optimize patient management in this clinical setting

The role of situations in situational judgment tests: Effects on construct saturation, predictive validity, and applicant perceptions

Recent theorizing and empirical evidence suggesting that Situational Judgment Tests (SDI's) are more context-independent than previously thought has sparked a debate about the role of situation descriptions in S.M. To contribute to this debate and add to our understanding of how SJTs work, this article conceptually embeds SJT performance in a situation construal model and examines the effects of situation descriptions on the construct saturation and predictive validity of SJT scores, as well as on applicant perceptions. Across two studies (N = 1,092 and 578) and different Sri's, personality and cognitive ability were equally important determinants of SJT performance regardless of whether situation descriptions were presented or omitted. The effects of removing situation descriptions on the criterion-related validity of SJT scores differed depending on the breadth of the criteria. For predicting global job performance criteria (in-role performance and organizational citizenship behavior), SJT validity was not significantly affected, whereas it decreased for predicting more specific criteria (interpersonal adaptability, efficacy for teamwork). Finally, the effects of omitting situation descriptions in SJTs on applicant perceptions were either negligible or small. Implications for SJT theory, research, and design are discussed

Perturbed proteostasis in autism spectrum disorders

Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes encoding regulators of mRNA translation and members of the UPS have been associated with an increased risk for the development of autism spectrum disorders. It is possible that these mutations result in a similar imbalance in protein homeostasis (proteostasis) at the synapse. This review will summarize recent work investigating the role of the UPS in synaptic plasticity at glutamatergic synapses, and propose that dysfunctional proteostasis is a common consequence of several genetic mutations linked to autism spectrum disorders. [Image: see text] Dynamic changes in synaptic strength rely on de novo protein synthesis and protein degradation by the ubiquitin proteasome system (UPS). Disruption of either of these cellular processes will result in significant impairments in synaptic plasticity and memory formation. Mutations in several genes encoding regulators of mRNA translation (i.e. FMR1) and protein degradation (i.e. UBE3A) have been associated with an increased risk for autism spectrum disorders and intellectual disability (ASD/ID). These mutations similarly disrupt protein homeostasis (proteostasis). Compensatory changes that reset the rate of proteostasis may contribute to the neurological symptoms of ASD/ID. This review summarizes recent work investigating the role of the UPS in synaptic plasticity at glutamatergic synapses, and proposes that dysfunctional proteostasis is a common consequence of several genetic mutations linked to ASD. This article is part of a mini review series: “Synaptic Function and Dysfunction in Brain Diseases”