Creative tourism and magic towns: Mocorito, Sinaloa

El subsector económico del turismo incentiva el crecimiento económico de microrregiones de México; mientras que la estrategia de promoción turística de pueblos mágico ha cobra vigencia y fuerza, despertando la curiosidad de los turistas para vivir experiencias arraigadas y endémicas de las regiones. El estudio tiene como objetivo, desarrollar un análisis teórico de los antecedentes del turismo y dar un panorama general del turismo en México, para finalizar con la evaluación de factores de motivos para el Pueblo Mágico de Mocorito, utilizando información científica y datos empíricos de la Región del Évora, donde esta geográficamente ubicado el Pueblo Mágico de Mocorito Sinaloa; a fin de conocer cuál es la principal motivación para visitar el lugar y así se puedan generar estrategias que permitan incentivar la economía con estrategias creativas de promoción turística para la región. Esto se llevó a cabo bajo una metodología cualitativa, de tipo exploratoria-descriptiva y aplicó el modelo geo detector por aglomeración, obteniendo como resultado que la marca destino, no es la principal motivación, si no los atributos que posee el Pueblo Mágico.  The economic subsector of tourism encourages the economic growth of micro-regions in Mexico; while the tourism promotion strategy of magical towns has gained validity and strength, arousing the curiosity of tourists to live rooted and endemic experiences of the regions. The objective of the study is to develop a theoretical analysis of the history of tourism and give an overview of tourism in Mexico, to end with the evaluation of motive factors for the Magical Town of Mocorito, using scientific information and empirical data from the Region. from Évora, where the Magic Town of Mocorito Sinaloa is geographically located; In order to know what is the main motivation to visit the place and thus strategies can be generated that allow to stimulate the economy with creative strategies of tourist promotion for the region. This was carried out under a qualitative methodology, of an exploratory-descriptive type and applied the geodetector model by agglomeration, obtaining as a result that the destination brand is not the main motivation, but rather the attributes that the Magical Town possesses

Validation of the new graded prognostic assessment scale for brain metastases: a multicenter prospective study

<p>Abstract</p> <p>Background</p> <p>Prognostic indexes are useful to guide tailored treatment strategies for cancer patients with brain metastasis (BM). We evaluated the new Graded Prognostic Assessment (GPA) scale in a prospective validation study to compare it with two published prognostic indexes.</p> <p>Methods</p> <p>A total of 285 newly diagnosed BM (<it>n </it>= 85 with synchronous BM) patients, accrued prospectively between 2000 and 2009, were included in this analysis. Mean age was 62 ± 12.0 years. The median KPS and number of BM was 70 (range, 20-100) and 3 (range, 1-50), respectively. The majority of primary tumours were lung (53%), or breast (17%) cancers. Treatment was administered to 255 (89.5%) patients. Only a minority of patients could be classified prospectively in a favourable prognostic class: GPA 3.5-4: 3.9%; recursive partitioning analysis (RPA) 1, 8.4% and Basic Score for BM (BSBM) 3, 9.1%. Mean follow-up (FU) time was 5.2 ± 4.7 months.</p> <p>Results</p> <p>During the period of FU, 225 (78.9%) patients died. The 6 months- and 1 year-OS was 36.9% and 17.6%, respectively. On multivariate analysis, performance status (<it>P </it>< 0.001), BSBM (<it>P </it>< 0.001), Center (<it>P </it>= 0.007), RPA (<it>P </it>= 0.02) and GPA (<it>P </it>= 0.03) were statistically significant for OS. The survival prediction performances' of all indexes were identical. Noteworthy, the significant OS difference observed within 3 months of diagnosis between the BSBM, RPA and GPA classes/groups was not observed after this cut-off time point. Harrell's concordance indexes <it>C </it>were 0.58, 0.61 and 0.58 for the GPA, BSBM and RPA, respectively.</p> <p>Conclusions</p> <p>Our data suggest that the new GPA index is a valid prognostic index. In this prospective study, the prediction performance was as good as the BSBM or RPA systems. These published indexes may however have limited long term prognostication capability.</p

Aplicación del modelo de sistema corporativo abierto para el manejo de la contabilidad administrativa del Grupo Empresarial SACSA

The objective is to apply an open corporate system model for the control of administrative accounting and the strategic management of income to avoid risks in the network of authorization or financing promoters that it offers SACSA Corporate. With a qualitative methodology, exploratory and descriptive, the case study method was used and the open corporate-operative system model was applied, to identify the driving and constraining forces of the organization's strategic management of sales and profits, which was complemented with the method of systematic analysis of scientific literature in correspondence to the administrative and strategic control of the companies. The findings reveal that the model allows optimizing the management of income and profit control, documenting the process in accounting and financial information reports through the open corporate system with operational and informative characteristics of administrative accounting, which must be closely linked to the technological development systems and human resource training systems. With its implementation, the operationalization of accounting and administrative information is improved, which allows the redefinition of responsibilities and functions of the personnel, in addition to promoting the creation of innovative strategies based on certification, aimed at factors involved in the sales process to obtain greater benefits and to improve the profitability of the company.El objetivo fue proponer la aplicación de un modelo de sistema corporativo abierto para el control de la contabilidad administrativa y el manejo estratégico de ingresos, a fin de evitar riesgos en la red de promotores de habilitación o financiamiento que ofrece el Grupo Empresarial SACSA. Con una metodología cualitativa, de tipo exploratoria y descriptiva, se utilizó el método de estudio de caso y aplicó el modelo de sistema corporativo-operativo abierto para identificar las fuerzas impulsoras y restrictivas del manejo estratégico de las ventas y las ganancias de la organización, lo que se complementó con el método de análisis sistemático de literatura científica en correspondencia al control administrativo y estratégico de las empresas. Los hallazgos revelan que el modelo permite optimizar el manejo del control de ingresos y ganancias, documentar el proceso en reportes de información contable y financiera a través del sistema corporativo abierto con características operativas e informativas de la contabilidad administrativa, que deben estar estrechamente vinculados a los sistemas de desarrollo tecnológico y a los sistemas de capacitación del recurso humano. Con su implementación se mejora la operacionalización de la información contable y administrativa, lo que permiten redefinir responsabilidades y funciones del personal, además de propiciar la creación de estrategias innovadoras de base certificada, dirigidas a factores involucrados en el proceso de ventas para obtener mayores beneficios y para mejorar la rentabilidad de la empresa

Columna cervical traumática : Hallazgos en tomografía computarizada multidetector

Se realiza una reseña histórica de la tomografía computarizada desde su inicio hasta la actualidad, así mismo una exhaustiva revisión de la anatomía, fisiología y patología traumática más frecuente de la columna cervical para finalmente presentar los datos estadísticos de la revisión realizada de las historias clínicas de los pacientes que ingresaron a nuestra institución con sospecha clínica de traumatismo de columna cervical y a quienes les fue realizada una tomografía computarizada multidetector, explicando los hallazgos radiológicos más frecuentes y su relación con los datos estadísticos tales como edad, género, mecanismo de la lesión y tipo de lesión cervical

Pronóstico de los recursos tangibles de las Pymes hoteleras del Municipio de Culiacán, Sinaloa, a través de sus prácticas sustentables

This research focuses on identifying which practices are implemented by hotels in the city of Culiacán, Sinaloa, to contribute to sustainable development and at the same time to measure their impact on maximizing their tangible resources. For this, a quantitative study approach was applied and the survey questionnaire based on the Likert scale was used as the information gathering technique. The research was exploratory, non-experimental and correlational, the study population was 21 hotels with more than 10 direct employees. The findings found show that of the 26 practices evaluated, 13 impact on the maximization of their resources, being those that group the economic dimension those that generate the greatest economic benefit. The aforementioned allowed the design of a simple linear regression statistical model useful for forecasting the profitability of lodging establishments through their sustainable practices.Esta investigación se enfoca en identificar cuáles son las prácticas que implementan los hoteles de la ciudad de Culiacán, Sinaloa, para contribuir al desarrollo sustentable y al mismo tiempo en medir la incidencia que estas tienen en la maximización de sus recursos tangibles. Para ello se aplicó un enfoque de estudio cuantitativo y se utilizó como técnica de recopilación de información el cuestionario tipo encuesta a partir de la escala de Likert. La investigación fue exploratoria, no experimental y correlacional, la población de estudio fueron 21 hoteles que registran más de 10 empleados directos. Los hallazgos encontrados muestran que de las 26 prácticas evaluadas, 13 impactan en la maximización de sus recursos, siendo las que agrupa la dimensión económica las que generan mayor beneficio económico. Lo antes mencionado permitió diseñar un modelo estadístico de regresión lineal simple útil para pronosticar la rentabilidad de los establecimientos de hospedaje a través de sus prácticas sustentables

Uso del mindfulness sobre indicadores de estrés en deportistas durante la etapa competitiva: Revisión sistemática

Mindfulness is a meditative practice that has proven to reduce psycho-physiological stress. Purpose: Analyze if mindfulness is effective to reduce psycho-physiological stress in athletes during their competitive season. Clinical studies that included different meditative techniques for stress reduction in athletes during the competitive phase was searched for in databases such as PubMed, Scopus and Web of Science (1985 to August 10, 2019), using the combinations of the words mindfulness, meditation, yoga, sport, athlete, intervention, stress, and cortisol. Only seven papers were located, three of them with a quantitative design, one as quantitative and three with mixed methodology. In the seven studies found (153 subjects; 134 men and 19 women) their authors mention that mindfulness was effective for reducing stress in athletes during the competitive season

Biological Signatures of Brain Damage Associated with High Serum Ferritin Levels in Patients with Acute Ischemic Stroke and Thrombolytic Treatment

Background and purpose: Increased body iron stores have been related to greater oxidative stress and brain injury in clinical and experimental cerebral ischemia and reperfusion. We aimed to investigate the biological signatures of excitotoxicity, inflammation and blood brain barrier disruption potentially associated with high serum ferritin levels-related damage in acute stroke patients treated with i.v. t-PA

Validation of the new graded prognostic assessment scale for brain metastases: a multicenter prospective study

Background: Prognostic indexes are useful to guide tailored treatment strategies for cancer patients with brain metastasis (BM). We evaluated the new Graded Prognostic Assessment (GPA) scale in a prospective validation study to compare it with two published prognostic indexes. Methods: A total of 285 newly diagnosed BM (n = 85 with synchronous BM) patients, accrued prospectively between 2000 and 2009, were included in this analysis. Mean age was 62 +/- 12.0 years. The median KPS and number of BM was 70 (range, 20-100) and 3 (range, 1-50), respectively. The majority of primary tumours were lung (53%), or breast (17%) cancers. Treatment was administered to 255 (89.5%) patients. Only a minority of patients could be classified prospectively in a favourable prognostic class: GPA 3.5-4: 3.9%; recursive partitioning analysis (RPA) 1, 8.4% and Basic Score for BM (BSBM) 3, 9.1%. Mean follow-up (FU) time was 5.2 +/- 4.7 months. Results: During the period of FU, 225 (78.9%) patients died. The 6 months-and 1 year-OS was 36.9% and 17.6%, respectively. On multivariate analysis, performance status (P < 0.001), BSBM (P < 0.001), Center (P = 0.007), RPA (P = 0.02) and GPA (P = 0.03) were statistically significant for OS. The survival prediction performances' of all indexes were identical. Noteworthy, the significant OS difference observed within 3 months of diagnosis between the BSBM, RPA and GPA classes/groups was not observed after this cut-off time point. Harrell's concordance indexes C were 0.58, 0.61 and 0.58 for the GPA, BSBM and RPA, respectively. Conclusions: Our data suggest that the new GPA index is a valid prognostic index. In this prospective study, the prediction performance was as good as the BSBM or RPA systems. These published indexes may however have limited long term prognostication capability