ASSESSMENT OF WATER QUALITY ANALYSIS USING PHYSICO-CHEMICAL PARAMETERS: A CASE STUDY OF BHIMA RIVER IN DAUND TAHSIL, PUNE DISTRICT, MAHARASHTRA.

Objective: Our objective is to examine the previous and current physical and chemical properties of the water in Bhima river in the study area as well as to assess the change in physical and chemical properties of the study area. Materials and Methods: The physico-chemical characteristics of Bhima river water in Daund Tahsil (Pune district) have been studied. The stretch of Bhima river in Daund Tahsil is extending downstream from Dahitane to Malthan. Bhima River was assessed at three various stations in terms of critical pollution parameters in the year 2010-11 and 2011-12. Three sampling stations viz., Station A-near Dahitane (Towards the West side), Station B-near Rahu (in the middle), and Station C-near Daund (towards East side) were established for the collection of water samples during April, 2011 to March, 2012. The water quality parameters namely transparency, colour, (transparent-very turbid), turbidity, total dissolved solids pH ,dissolved oxygen, free carbon dioxide, total alkalinity, Biochemical Oxygen Demand, Chemical Oxygen Demand, total hardness, chloride, nitrate, nitrite, sulphate, phosphate , silicate, sodium, potassium, Calcium and Magnesium reflects on the nature of the river in the study area. Results: On the basis of various parameters studied it was found that the rivers receive industrial effluents from various industries, which are situated on the bank of river, along with the heavy loads of agriculture run off. Conclusion: The conclusion also deals with community response about Bhima river out of the many problems perceived by the river bank residents, the priority problem observed by maximum is that of the mosquitoes and habitants, Agriculture, including commercial livestock and poultry farming. is the source of many organic and inorganic pollutants in surface waters and ground water. Hence the river water quality is needed to be improve

Improved Bernstein Optimization Based Nonlinear Model Predictive Control Scheme for Power Systems

© 2017 This paper presents a improved Bernstein global optimization algorithm based model predictive control (MPC) scheme for the nonlinear systems. A new improvement in the Bernstein algorithm is the introduction of a box pruning operator, which during a branch-and-bound search, discard portions of the solution search space that do not contain global solution, thereby speeding up the algorithm. The applicability of this MPC scheme is demonstrated with a simulation studies on a nonlinear single machine infinite bus power system over a wide range of operating conditions. The simulation results show improvement in the system damping and settling time compared with the classical power system stabilizer and partial feedback linearization control schemes.National Research Foundation, Singapore

Nonlinear model predictive control based on Bernstein global optimization with application to a nonlinear CSTR

© 2016 EUCA. We present a model predictive control based tracking problem for nonlinear systems based on global optimization. Specifically, we introduce a 'Bernstein global optimization' procedure and demonstrate its applicability to the aforementioned control problem. This Bernstein global optimization procedure is applied to predictive control of a nonlinear CSTR system. Its strength and benefits are compared with those of a sub-optimal procedure, as implemented in MATLAB using fmincon function, and two well established global optimization procedures, BARON and BMIBNB.National Research Foundation, Singapore

Model predictive control of a CSTR: A comparative study among linear and nonlinear model approaches

© 2017 IEEE. This paper presents a comparative study of two widely accepted model predictive control schemes based on mixed logical dynamical (MLD) and nonlinear modeling approaches with application to a continuous stirred tank reactor (CSTR) system. Specifically, we approximate the nonlinear behavior of a CSTR system with multiple local linear models in a MLD framework. The main benefit of such a scheme is the significant improvement in model accuracy when compared with a single linearized model. The benefits and trade-offs associated with predictive control laws synthesized using MLD and nonlinear modeling approaches are also compared.National Research Foundation, Singapore

A trust-region based sequential linear programming approach for AC optimal power flow problems

© 2018 Elsevier B.V. This study proposes a new trust-region based sequential linear programming algorithm to solve the AC optimal power flow (OPF) problem. The OPF problem is solved by linearizing the cost function, power balance and engineering constraints of the system, followed by a trust-region to control the validity of the linear model. To alleviate the problems associated with the infeasibilities of a linear approximation, a feasibility restoration phase is introduced. This phase uses the original nonlinear constraints to quickly locate a feasible point when the linear approximation is infeasible. The algorithm follows convergence criteria to satisfy the first order optimality conditions for the original OPF problem. Studies on standard IEEE systems and large-scale Polish systems show an acceptable quality of convergence to a set of best-known solutions and a substantial improvement in computational time, with linear scaling proportional to the network size.National Research Foundation, Singapore

Experiments with hybrid Bernstein global optimization algorithm for the OPF problem in power systems

This paper presents an algorithm based on the Bernstein form of polynomials for solving the optimal power flow (OPF) problem in electrical power networks. The proposed algorithm combines local and global optimization methods and is therefore referred to as a `hybrid' Bernstein algorithm in the context of this work. The proposed algorithm is a branch-and-bound (B&B) procedure wherein a local search method is used to obtain a good upper bound on the global minimum at each branching node. Subsequently, the Bernstein form of polynomials is used to obtain a lower bound on the global minimum. The performance of the proposed algorithm is compared with the previously reported Bernstein algorithm to demonstrate its effi cacy in terms of the chosen performance metrics. Furthermore, the proposed algorithm is tested by solving the OPF problem for several benchmark IEEE power system examples and its performance is compared with generic global optimization solvers such as BARON and COUENNE. The test results demonstrate that the algorithm HBBB delivers satisfactory performance in terms of solution optimality.This research is supported by the National Research Foundation, Prime Ministers Office, Singapore, under its CREATE programme

Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015

SummaryBackground The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors—the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI). Findings Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57·8% (95% CI 56·6–58·8) of global deaths and 41·2% (39·8–42·8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211·8 million [192·7 million to 231·1 million] global DALYs), smoking (148·6 million [134·2 million to 163·1 million]), high fasting plasma glucose (143·1 million [125·1 million to 163·5 million]), high BMI (120·1 million [83·8 million to 158·4 million]), childhood undernutrition (113·3 million [103·9 million to 123·4 million]), ambient particulate matter (103·1 million [90·8 million to 115·1 million]), high total cholesterol (88·7 million [74·6 million to 105·7 million]), household air pollution (85·6 million [66·7 million to 106·1 million]), alcohol use (85·0 million [77·2 million to 93·0 million]), and diets high in sodium (83·0 million [49·3 million to 127·5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa. Interpretation Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden. Funding Bill & Melinda Gates Foundation

The Intrinsic Resolution Limit in the Atomic Force Microscope: Implications for Heights of Nano-Scale Features

Background; Accurate mechanical characterization by the atomic force microscope at the highest spatial resolution requires that topography is deconvoluted from indentation. The measured height of nanoscale features in the atomic force microscope (AFM) is almost always smaller than the true value, which is often explained away as sample deformation, the formation of salt deposits and/or dehydration. We show that the real height of nano-objects cannot be obtained directly: a result arising as a consequence of the local probe-sample geometry. Methods and Findings; We have modeled the tip-surface-sample interaction as the sum of the interaction between the tip and the surface and the tip and the sample. We find that the dynamics of the AFM cannot differentiate between differences in force resulting from 1) the chemical and/or mechanical characteristics of the surface or 2) a step in topography due to the size of the sample; once the size of a feature becomes smaller than the effective area of interaction between the AFM tip and sample, the measured height is compromised. This general result is a major contributor to loss of height and can amount to up to ∼90% for nanoscale features. In particular, these very large values in height loss may occur even when there is no sample deformation, and, more generally, height loss does not correlate with sample deformation. DNA and IgG antibodies have been used as model samples where experimental height measurements are shown to closely match the predicted phenomena. Conclusions; Being able to measure the true height of single nanoscale features is paramount in many nanotechnology applications since phenomena and properties in the nanoscale critically depend on dimensions. Our approach allows accurate predictions for the true height of nanoscale objects and will lead to reliable mechanical characterization at the highest spatial resolution

A model-based approach to selection of tag SNPs

BACKGROUND: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identification of sets of tag SNPs that capture as much haplotype information as possible. Tag SNP selection is analogous to the problem of data compression in information theory. According to Shannon's framework, the optimal tag set maximizes the entropy of the tag SNPs subject to constraints on the number of SNPs. This approach requires an appropriate probabilistic model. Compared to simple measures of Linkage Disequilibrium (LD), a good model of haplotype sequences can more accurately account for LD structure. It also provides a machinery for the prediction of tagged SNPs and thereby to assess the performances of tag sets through their ability to predict larger SNP sets. RESULTS: Here, we compute the description code-lengths of SNP data for an array of models and we develop tag SNP selection methods based on these models and the strategy of entropy maximization. Using data sets from the HapMap and ENCODE projects, we show that the hidden Markov model introduced by Li and Stephens outperforms the other models in several aspects: description code-length of SNP data, information content of tag sets, and prediction of tagged SNPs. This is the first use of this model in the context of tag SNP selection. CONCLUSION: Our study provides strong evidence that the tag sets selected by our best method, based on Li and Stephens model, outperform those chosen by several existing methods. The results also suggest that information content evaluated with a good model is more sensitive for assessing the quality of a tagging set than the correct prediction rate of tagged SNPs. Besides, we show that haplotype phase uncertainty has an almost negligible impact on the ability of good tag sets to predict tagged SNPs. This justifies the selection of tag SNPs on the basis of haplotype informativeness, although genotyping studies do not directly assess haplotypes. A software that implements our approach is available