A Battery of soil and plant indicators of NBS environmental performance in the context of global change

Nature-based solutions (NBSs) for risk reduction produce environmental effects that must be assessed to evaluate their performance. In a context of climate change and growing concern about the loss of biodiversity, indicators informing about ecosystem complexity, resilience and stability are required. NBS projects hardly ever include environmental monitoring programs and, at best, NBS performance is evaluated based on elementary indicators that provide poor information about ecosystem functions and services. Within the framework of the PHUSICOS (EU, H2020) project, a NBS approach is being applied to reduce the hydrometeorological risks (rock falls and snow avalanches) that threaten a transnational road and a very populated town in the Pyrenees range. In both cases, the planned actions are modifying soil and vegetation structure and functioning as well as the environmental services they provide. Here we present a set of soil and plant indicators designed to be included in the postoperation monitoring plan of both NBS projects. We provide a description and information about the range of values of every indicator measured in the study sites together with indications about analytical methods and sampling calendar. We discuss the trade-offs between monetary cost, expertise requirements and meaningfulness of the indicators

Effects of Albumin on Survival after a Hepatic Encephalopathy Episode: Randomized Double-Blind Trial and Meta-Analysis

Albúmina; Assaig clínic; MetanàlisiAlbumin; Clinical trial; Meta-analysisAlbúmina; Ensayo clínico; MetaanálisisNo therapies have been proven to increase survival after a hepatic encephalopathy (HE) episode. We hypothesize that two doses of albumin could improve 90-day survival rates after a HE episode. Methods: (1) A randomized double-blind, placebo-controlled trial (BETA) was conducted in 12 hospitals. The effect of albumin (1.5 g/kg at baseline and 1 g/kg on day 3) on 90-day survival rates after a HE episode grade II or higher was evaluated. (2) A meta-analysis of individual patient’s data for survival including two clinical trials (BETA and ALFAE) was performed. Results: In total, 82 patients were included. Albumin failed to increase the 90-day transplant-free survival (91.9% vs. 80.5%, p = 0.3). A competing risk analysis was performed, observing a 90-day cumulative incidence of death of 9% in the albumin group vs. 20% in the placebo (p = 0.1). The meta-analysis showed a benefit in the albumin group, with a lower rate of clinical events (death or liver transplant) than patients in the placebo (HR, 0.44; 95% CI, 0.21–0.82), when analyzed by a competing risk analysis (90-days mortality rate of 11% in the albumin group vs. 30% in the placebo, p = 0.02). Conclusions: Repeated doses of albumin might be beneficial for patient’s survival as an add-on therapy after an HE episode, but an adequately powered trial is needed.This work was supported by grants ICI14/00352 and PI/18/00947 from Instituto de Salud Carlos III (ISCIII) and co-funded by the European Union (ERDF/ESF, “Investing in your future”—Una manera de hacer Europa). MVC and MST are both recipients of Juan Rodes grants from ISCIII. JG is a recipient of a research intensification grant from the ISCIII. CIBERehd is supported by ISCIII. ACS is a recipient of the Rio Hortega grant from ISCIII. The work was independent of all funding

Size dependence of refractive index of Si nanoclusters embedded in SiO2

he complex refractive index of SiO2 layers containing Si nanoclusters (Si-nc) has been measured by spectroscopic ellipsometry in the range from 1.5 to 5.0 eV. It has been correlated with the amount of Si excess accurately measured by x-ray photoelectron spectroscopy and the nanocluster size determined by energy-filtered transmission electron microscopy. The Si-nc embedded in SiO2 have been produced by a fourfold Si+ ion implantation, providing uniform Si excess aimed at a reliable ellipsometric modeling. The complex refractive index of the Si-nc phase has been calculated by the application of the Bruggeman effective-medium approximation to the composite media. The characteristic resonances of the refractive index and extinction coefficient of bulk Si vanish out in Si-nc. In agreement with theoretical simulations, a significant reduction of the refractive index of Si-nc is observed, in comparison with bulk and amorphous silicon. The knowledge of the optical properties of these composite layers is crucial for the realization of Si-based waveguides and light-emitting devices

Excess mortality among older adults institutionalized in long-term care facilities during the COVID-19 pandemic: a population-based analysis in Catalonia

Objectives: To assess excess mortality among older adults institutionalized in nursing homes within the successive waves of the COVID-19 pandemic in Catalonia (north-east Spain).Design: Observational, retrospective analysis of population-based central healthcare registries.Setting and participants: Individuals aged >65 years admitted in any nursing home in Catalonia between January 1, 2015, and April 1, 2022.Methods Deaths reported during the pre-pandemic period (2015-2019) were used to build a reference model for mortality trends (a Poisson model, due to the event counting nature of the variable mortality), adjusted by age, sex, and clinical complexity, defined according to the adjusted morbidity groups. Excess mortality was estimated by comparing the observed and model-based expected mortality during the pandemic period (2020-2022). Besides the crude excess mortality, we estimated the standardized mortality rate (SMR) as the ratio of weekly deaths' number observed to the expected deaths' number over the same period.Results: The analysis included 175,497 older adults institutionalized (mean 262 days, SD 132), yielding a total of 394,134 person-years: 288,948 person-years within the reference period (2015-2019) and 105,186 within the COVID-19 period (2020-2022). Excess number of deaths in this population was 5,403 in the first wave and 1,313, 111, -182, 498, and 329 in the successive waves. The first wave on March 2020 showed the highest SMR (2.50; 95% CI 2.45-2.56). The corresponding SMR for the 2nd to 6th waves were 1.31 (1.27-1.34), 1.03 (1.00-1.07), 0.93 (0.89-0.97), 1.13 (1.10-1.17), and 1.07 (1.04-1.09). The number of excess deaths following the first wave ranged from 1,313 (2nd wave) to -182 (4th wave). Excess mortality showed similar trends for men and women. Older adults and those with higher comorbidity burden account for higher number of deaths, albeit lower SMRs.Conclusion: Excess mortality analysis suggest a higher death toll of the COVID-19 crisis in nursing homes than in other settings. Although crude mortality rates were far higher among older adults and those at higher health risk, younger individuals showed persistently higher SMR, indicating an important death toll of the COVID-19 in these groups of people

Anàlisis, definició, validació i implementació dels mètodes d'avaluació de les competències transversals en els nous graus TIC a l'EPSEVG.

La finalitat del projecte és identificar, avaluar i descriure com incorporar els mètodes d'avaluació de les competències transversals dels nous graus directament relacionats amb el sector TIC que s'impartiran a l'Escola Politècnica Superior de Vilanova i la Geltrú. El sorgiment del nou Espai Europeu d’Educació Superior planteja un nou enfocament i grans interrogants en el disseny dels plans d'estudi dels diferents títols universitaris d'enginyeria, i en concret en aquelles enginyeries orientades al sector de les tecnologies de la informació i la comunicació (TIC). Aquest projecte pretén crear un marc per al disseny d'aquestes titulacions emparant-nos en el nou paradigma educatiu que representa l'anomenat comunament procés Bologna, considerant com a fonamental la definició del terme competència transversal i extrapolant-la a l'àmbit del sector TIC, i fent especial èmfasi en l'ús de metodologies docents actives, oferint a l'estudiant un paper molt important en la tasca d'aprenentatge. Per a això, estructurem el projecte en 2 fases. En la primera fase es pretén definir el terme competència transversal en l'actualitat i delimitar un llistat de 20 competències transversals associades al sector TIC. Aquest llistat ens ha permès realitzar una enquesta a 43 empreses del sector per a poder determinar quines competències genèriques són les més valorades per tal que els nous llicenciats en enginyeria puguin inserir-se professionalment en el sector TIC, segons la demanda del sector a Espanya. En la segona fase, corresponent a l'article es realitza un anàlisi de les diferents metodologies docents actives presents en l'actualitat, per procedir a fer una selecció, mitjançant un panell d'experts, de les metodologies que ens assegurin l'adquisició de les 10 competències transversals millor valorades per les empreses del sector.Peer Reviewe

The 2011 October Draconids outburst. I. Orbital elements, meteoroid fluxes and 21P/Giacobini-Zinner delivered mass to Earth

On October 8th, 2011 the Earth crossed the dust trails left by comet 21P/Giacobini-Zinner during its XIX and XX century perihelion approaches with the comet being close to perihelion. The geometric circumstances of that encounter were thus favorable to produce a meteor storm, but the trails were much older than in the 1933 and 1946 historical encounters. As a consequence the 2011 October Draconid display exhibited several activity peaks with Zenithal Hourly Rates of about 400 meteors per hour. In fact, if the display had been not forecasted, it could have passed almost unnoticed as was strongly attenuated for visual observers due to the Moon. This suggests that most meteor storms of a similar nature could have passed historically unnoticed under unfavorable weather and Moon observing conditions. The possibility of obtaining information on the physical properties of cometary meteoroids penetrating the atmosphere under low-geocentric velocity encounter circumstances motivated us to set up a special observing campaign. Added to the Spanish Fireball Network wide-field all-sky and CCD video monitoring, other high-sensitivity 1/2" black and white CCD video cameras were attached to modified medium-field lenses for obtaining high resolution orbital information. The trajectory, radiant, and orbital data of 16 October Draconid meteors observed at multiple stations are presented. The results show that the meteors appeared from a geocentric radiant located at R.A.=263.0+-0.4 deg. and Dec.=+55.3+-0.3 deg. that is in close agreement with the radiant predicted for the 1873-1894 and the 1900 dust trails. The estimated mass of material from 21P/Giacobini-Zinner delivered to Earth during the six-hours outburst was around 950+-150 kg.Comment: Manuscript in press in Monthly Notices of the Royal Astronomical Society, submitted to MNRAS on November 16th, 2012 Accepted for publication in MNRAS on April 28th, 2013 Manuscript Pages: 21 Tables: 8 Figures: 4 Manuscript associated: "The 2011 October Draconids outburst. II. Meteoroid chemical abundances from fireball spectroscopy" by J.M. Madiedo is also in press in the same journa

Excess mortality among older adults institutionalized in long-term care facilities during the COVID-19 pandemic: a population-based analysis in Catalonia

ObjectivesTo assess excess mortality among older adults institutionalized in nursing homes within the successive waves of the COVID-19 pandemic in Catalonia (north-east Spain).DesignObservational, retrospective analysis of population-based central healthcare registries.Setting and participantsIndividuals aged >65 years admitted in any nursing home in Catalonia between January 1, 2015, and April 1, 2022.MethodsDeaths reported during the pre-pandemic period (2015–2019) were used to build a reference model for mortality trends (a Poisson model, due to the event counting nature of the variable “mortality”), adjusted by age, sex, and clinical complexity, defined according to the adjusted morbidity groups. Excess mortality was estimated by comparing the observed and model-based expected mortality during the pandemic period (2020–2022). Besides the crude excess mortality, we estimated the standardized mortality rate (SMR) as the ratio of weekly deaths’ number observed to the expected deaths’ number over the same period.ResultsThe analysis included 175,497 older adults institutionalized (mean 262 days, SD 132), yielding a total of 394,134 person-years: 288,948 person-years within the reference period (2015–2019) and 105,186 within the COVID-19 period (2020–2022). Excess number of deaths in this population was 5,403 in the first wave and 1,313, 111, −182, 498, and 329 in the successive waves. The first wave on March 2020 showed the highest SMR (2.50; 95% CI 2.45–2.56). The corresponding SMR for the 2nd to 6th waves were 1.31 (1.27–1.34), 1.03 (1.00–1.07), 0.93 (0.89–0.97), 1.13 (1.10–1.17), and 1.07 (1.04–1.09). The number of excess deaths following the first wave ranged from 1,313 (2nd wave) to −182 (4th wave). Excess mortality showed similar trends for men and women. Older adults and those with higher comorbidity burden account for higher number of deaths, albeit lower SMRs.ConclusionExcess mortality analysis suggest a higher death toll of the COVID-19 crisis in nursing homes than in other settings. Although crude mortality rates were far higher among older adults and those at higher health risk, younger individuals showed persistently higher SMR, indicating an important death toll of the COVID-19 in these groups of people

Melatonin receptors MT1 and MT2 are expressed in spermatozoa from several seasonal and nonseasonal breeder species

P. 1958-1968Melatonin is a ubiquitous and multipurpose molecule, and one of its roles is to regulate reproduction in some seasonal mammals. Our group has previously reported the variation in the melatonin levels in ram seminal plasma along the year and identified MT1 and MT2 receptors in ram spermatozoa. The objective of this study was to elucidate whether the presence of melatonin receptors (MT1 and MT2) in the sperm plasma membrane, and melatonin in the seminal plasma is related to seasonal breeding. For this purpose, the presence of melatonin receptors and the levels of melatonin in seminal plasma have been examined in several species: donkey and stallion as long-day breeders; red deer as a wild, short-day, highly seasonal breeder (epididymal spermatozoa); bull as a conventional nonseasonal breeder; boar as a seasonal breeder under management techniques; and dog as possible a seasonal breeder not regulated by melatonin. We have detected measurable levels of melatonin in the seminal plasma of all ejaculated semen samples (from donkey, stallion, boar, bull, and dog). Also, and for the first time, we have demonstrated the presence of MT1 and MT2 melatonin receptors in the spermatozoa of all these species, regardless their type of reproduction or sperm source (ejaculated or epididymal), using indirect immunofluorescence techniques and Western blotting. Our findings suggest that melatonin and melatonin receptors may be universally distributed in the reproductive system of mammals and that the sperm melatonin receptors cells may not be necessarily related with seasonal reproduction. Furthermore, the presence of MT1 at the cytoplasmic droplet in immature ejaculated stallion spermatozoa found in one sample and epididymal red deer spermatozoa suggests that melatonin may be involved in specific functions during spermatogenesis and sperm maturation, like protecting spermatozoa from oxidative damage, this activity being mediated through these receptors.S

Anàlisi, definició, validació i implementació dels mètodes d'avaluació de les competències transversals en els nous graus TIC a l'EPSEVG

La finalitat del projecte és identificar, avaluar i descriure com incorporar els mètodes d'avaluació de les competències transversals dels nous graus directament relacionats amb el sector TIC que s'impartiran a l'Escola Politècnica Superior de Vilanova i la Geltrú. El sorgiment del nou Espai Europeu d’Educació Superior planteja un nou enfocament i grans interrogants en el disseny dels plans d'estudi dels diferents títols universitaris d'enginyeria, i en concret en aquelles enginyeries orientades al sector de les tecnologies de la informació i la comunicació (TIC). Aquest projecte pretén crear un marc per al disseny d'aquestes titulacions emparant-nos en el nou paradigma educatiu que representa l'anomenat comunament procés Bologna, considerant com a fonamental la definició del terme competència transversal i extrapolant-la a l'àmbit del sector TIC, i fent especial èmfasi en l'ús de metodologies docents actives, oferint a l'estudiant un paper molt important en la tasca d'aprenentatge. Per a això, estructurem el projecte en 2 fases. En la primera fase es pretén definir el terme competència transversal en l'actualitat i delimitar un llistat de 20 competències transversals associades al sector TIC. Aquest llistat ens ha permès realitzar una enquesta a 43 empreses del sector per a poder determinar quines competències genèriques són les més valorades per tal que els nous llicenciats en enginyeria puguin inserir-se professionalment en el sector TIC, segons la demanda del sector a Espanya. En la segona fase, es realitza un anàlisi de les diferents metodologies docents actives presents en l'actualitat, per procedir a fer una selecció, mitjançant un panell d'experts, de les metodologies que ens assegurin l'adquisició de les 10 competències transversals millor valorades per les empreses del sector.Postprint (published version

Community-acquired pneumonia management in a short-stay unit: analysis of safety and efficacy

Podeu consultar la versió en castellà a: http://hdl.handle.net/2445/119397Background and objective: Community-acquired pneumonia (CAP) is a highly prevalent disease that often requires hospital admission. We aimed to assess the safety and efficacy of treating CAP in a short-stay unit as an alternative to conventional hospitalization. Methods: Retrospective comparison of patients admitted to a tertiary care hospital with a diagnosis of CAP between November 2005 and April 2007. We compared outcomes for cases managed in the 2 locations (short-stay unit vs conventional hospital ward), excluding patients who required intensive care. Variables and outcomes analyzed were age, sex, Charlson index, mean weight in the diagnosis-related group, scores on the CURB-65 criteria and the Pneumonia Severity Index (PSI), findings of microbiology, and readmission and mortality rates. Results: A total of 606 patients were studied; 187 were treated in the short-stay unit and 419 were admitted to the conventional ward. The main significant differences between the 2 groups were mean age (77.3 vs 67.9 years, respectively; P<.0001) and mean stay (3.48 vs 7.89 days; P<.0001). These differences were also reflected in the comparison between severity subgroups (by PSI). Mortality rates did not differ. Conclusions: Our experience with the short-stay unit suggests it offers a safe and effective way to manage CAP and leads to a significantly shorter hospital stay in comparison with conventional hospitalization, without increasing readmission and mortality rates