Liberalism in Religion and Other Sermons

The words Liberal and Liberalism at once arouse a spirit of mistrust in many minds, which become unsympathetic, irreceptive, and resentful. Even those who appropriate these words in politics are less ready to adopt them in religion. Indeed, it seems as though men had but a strictly limited quantity of mental motor energy, and that those who expend it in one kind of movement have none left for any other. Certainly the sects which are supposed to be the backbone of political Liberalism are the most obstinately immoveable in religion; and men ever ready to catch the first breeze impelling to political change have remained stolid as stone to the impulses of spiritual progress. Like Lot\u27s wife, their eyes are fixed on the past, and they cannot stir. But the title I have given to these Sermons carries with it no political connotation.https://place.asburyseminary.edu/ecommonsatsdigitalresources/1066/thumbnail.jp

Biosynthesis and enzymology of the Caenorhabditis elegans cuticle: identification and characterization of a novel serine protease inhibitor.

The nematode Caenorhabditis elegans represents an excellent model in which to examine nematode gene expression and function. A completed genome, straightforward transgenesis, available mutants and practical genome-wide RNAi approaches provide an invaluable toolkit in the characterization of nematode genes. We have performed a targeted RNAi screen in an attempt to identify components of the cuticle collagen biosynthetic pathway. Collagen biosynthesis and cuticle assembly are multi-step processes that involve numerous key enzymes involved in post-translational modification, trimer folding, procollagen processing and subsequent cross-linking stages. Many of these steps, the modifications and the enzymes are unique to nematodes and may represent attractive targets for the control of parasitic nematodes. A novel serine protease inhibitor was uncovered during our targeted screen, which is involved in collagen maturation, proper cuticle assembly and the moulting process. We have confirmed a link between this inhibitor and the previously uncharacterized bli-5 locus in C. elegans. The mutant phenotype, spatial expression pattern and the over-expression phenotype of the BLI-5 protease inhibitor and their relevance to collagen biosynthesis are discussed

Interpretation of the Θ+ as an Isotensor Pentaquark With Weakly Decaying Partners

The Θ+(1540), recently observed at LEPS, DIANA and CLAS, is hypothesized to be an isotensor resonance. This implies the existence of a multiplet where the Θ++, Θ+ and Θ0 have isospin-violating strong decays, and the Θ+++ and Θ− have weak decays and so are long-lived. Production mechanisms for the weakly-decaying states are discussed. The JP assignment of the Θ is most likely 1/2− or 3/2−

The golden death bacillus Chryseobacterium nematophagum is a novel matrix digesting pathogen of nematodes

Background: Nematodes represent important pathogens of humans and farmed animals and cause significant health and economic impacts. The control of nematodes is primarily carried out by applying a limited number of anthelmintic compounds, for which there is now widespread resistance being reported. There is a current unmet need to develop novel control measures including the identification and characterisation of natural pathogens of nematodes. Results: Nematode killing bacilli were isolated from a rotten fruit in association with wild free-living nematodes. These bacteria belong to the Chryseobacterium genus (golden bacteria) and represent a new species named Chryseobacterium nematophagum. These bacilli are oxidase-positive, flexirubin-pigmented, gram-negative rods that exhibit gelatinase activity. Caenorhabditis elegans are attracted to and eat these bacteria. Within 3 h of ingestion, however, the bacilli have degraded the anterior pharyngeal chitinous lining and entered the body cavity, ultimately killing the host. Within 24 h, the internal contents of the worms are digested followed by the final digestion of the remaining cuticle over a 2–3-day period. These bacteria will also infect and kill bacterivorous free-living (L1-L3) stages of all tested parasitic nematodes including the important veterinary Trichostrongylids such as Haemonchus contortus and Ostertagia ostertagi. The bacteria exhibit potent collagen-digesting properties, and genome sequencing has identified novel metalloprotease, collagenase and chitinase enzymes representing potential virulence factors. Conclusions: Chryseobacterium nematophagum is a newly discovered pathogen of nematodes that rapidly kills environmental stages of a wide range of key nematode parasites. These bacilli exhibit a unique invasion process, entering the body via the anterior pharynx through the specific degradation of extracellular matrices. This bacterial pathogen represents a prospective biological control agent for important nematode parasites

Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients: A cohort study

Definitions of comorbid conditions. (DOCX 13 kb

Unpacking Oakland Cemetery: Immersing Students in Atlanta History

Working with Oakland Cemetery, Georgia State and Emory Universities, and Beam Imagination are creating an experimental, public-facing digital archive that combines maps, a burial database, 3D visualizations, and curation

Reflections on a 'virtual' practice development unit: changing practice through identity development

Aims. This paper draws together the personal thoughts and critical reflections of key people involved in the establishment of a ‘virtual’ practice development unit of clinical nurse specialists in the south of England. Background. This practice development unit is ‘virtual’ in that it is not constrained by physical or specialty boundaries. It became the first group of Trust-wide clinical nurse specialists to be accredited in the UK as a practice development unit in 2004. Design and methods. The local university was asked to facilitate the accreditation process via 11 two-hour audio-recorded learning sessions. Critical reflections from practice development unit members, leaders and university staff were written 12 months after successful accreditation, and the framework of their content analysed. Findings and discussion. Practice development was seen as a way for the clinical nurse specialists to realize their potential for improving patient care by transforming care practice in a collaborative, interprofessional and evolutionary manner. The practice development unit provided a means for these nurses to analyse their role and function within the Trust. Roberts’ identity development model for nursing serves as a useful theoretical underpinning for the reflections contained in this paper. Conclusions. These narratives provide another example of nurses making the effort to shape and contribute to patient care through organizational redesign. This group of nurses began to realize that the structure of the practice development unit process provided them with the means to analyse their role and function within the organization and, as they reflected on this structure, their behaviour began to change. Relevance to clinical practice. Evidence from these reflections supports the view that practice development unit participants have secured a positive and professional identity and are, therefore, better able to improve the patient experience

Y(2175): Distinguish Hybrid State from Higher Quarkonium

The possibility of Y(2175) as a $2{^3D_1}$ $s\bar{s}$ meson is studied. We study the decay of $2{^3D_1}$ $s\bar{s}$ from both the $^3P_0$ model and the flux tube model, and the results are similar in the two models. We show that the decay patterns of $1^{--}$ strangeonium hybrid and $2{^3D_1}$ $s\bar{s}$ are very different. The experimental search of the decay modes $KK$, $K^{*}K^{*}$, $K(1460)K$, $h_1(1380)\eta$ is suggested to distinguish the two pictures. Measuring the $K^{*}K^{*}$ partial width ratios is crucial to discriminate the $2{^3D_1}$ from the $3{^3S_1}$ $s\bar{s}$ assignment.Comment: 13 pages, 8 figure

Interpretation of the Theta+ as an isotensor pentaquark with weakly decaying partners

The Theta+(1540), recently observed at LEPS, DIANA and CLAS, is hypothesized to be an isotensor resonance. This implies the existence of a multiplet where the Theta++, Theta+ and Theta0 have isospin-violating strong decays, and the Theta+++ and Theta- have weak decays and so are long-lived. Production mechanisms for these states are discussed. The J^P assignment of the Theta is most likely 1/2^- or 3/2^-.Comment: references added, section on pentaquark model revised, 11 pages, LaTeX, accepted for publication in Physics Letters

National Diet and Nutrition Survey Rolling programme Years 9 to 11 (2016/2017 to 2018/2019) - A survey carried out on behalf of Public Health England and the Food Standards Agency

The National Diet and Nutrition Survey Rolling Programme (NDNS RP) is a continuous crosssectional survey, designed to assess the diet, nutrient intake and nutritional status of the general population aged 1.5 years and over living in private households in the UK. A representative sample of around 1,000 people (500 adults and 500 children) take part in the NDNS RP each year. Fieldwork for Years 9 to 11 of the NDNS RP was carried out between April 2016 and June 2019. The survey comprised an interview, a 4-day estimated diet diary, physical measurements and a blood and urine sample. Results are used by government to monitor progress toward diet and nutrition objectives of UK Health Departments and to develop policy interventions. The foods, nutrients and blood and urine measures presented in this report were selected for their nutritional and public health relevance to current dietary concerns in the UK. Results are analysed for 7 age groups: 1.5 to 3 years; 4 to 10 years; 11 to 18 years; 19 to 64 years; 65 years and over; 65 to 74 years and 75 years and over, split by sex in all except the youngest age group. The report includes: • descriptive statistics of food consumption, nutrient intake and nutritional status including proportion of the population meeting government recommendations for NDNS RP Years 9 to 11 (2016/17 to 2018/19) and comparison with results from years 7&8 (2014/15 to 2015/16). • trends over time in relation to food consumption, nutrient intakes and nutritional status in the UK for the first 11 years of the NDNS RP (2008/09 to 2018/19)PHE and Food Standards Agenc