397 research outputs found
A complete sample of quasars from the 7C redshift survey
We present details of a new sample of radio-loud quasars drawn from 0.013 sr
of the 7C Redshift Survey. This sample is small (21 quasars) but complete in
that every object with an unresolved nucleus and/or broad emission lines with
S(151MHz) > 0.5 Jy has been discovered. The dependence of the quasar fraction
with redshift and radio luminosity is investigated, providing new evidence
supporting the unification of radio-loud quasars and powerful radio galaxies.
This 7C sample is compared with optically-selected quasars, in order to
determine whether there are systematic biases in the different selection
techniques. There are no lightly reddened (Av approx. 1) quasars in our sample
amongst the 14 with z < 2. The discovery of a reddened quasar at z = 2.034 and
its implications are discussed. A tight correlation between radio luminosity
and optical/near infrared continuum luminosity for a subset of the sample is
also found.Comment: 6 pages Latex, To appear in the "Cosmology with the New Radio
Surveys" Conference - Tenerife 13-15 January 199
MicroRNA expression in lymphocyte development and malignancy
This article is available open access through the publisher’s website. Copyright @ 2008 Macmillan Publishers Limited.No abstract available.The Leukemia Research Fund, the Julian Starmer-Smith Memorial Fund, and the Medical Research Council
Social Determinants of Community Health Services Utilization among the Users in China: A 4-Year Cross-Sectional Study
Background To identify social factors determining the frequency of community health service (CHS) utilization among CHS users in China. Methods Nationwide cross-sectional surveys were conducted in 2008, 2009, 2010, and 2011. A total of 86,116 CHS visitors selected from 35 cities were interviewed. Descriptive analysis and multinomial logistic regression analysis were employed to analyze characteristics of CHS users, frequency of CHS utilization, and the socio-demographic and socio-economic factors influencing frequency of CHS utilization. Results Female and senior CHS clients were more likely to make 3–5 and ≥6 CHS visits (as opposed to 1–2 visits) than male and young clients, respectively. CHS clients with higher education were less frequent users than individuals with primary education or less in 2008 and 2009; in later surveys, CHS clients with higher education were the more frequent users. The association between frequent CHS visits and family income has changed significantly between 2008 and 2011. In 2011, income status did not have a discernible effect on the likelihood of making ≥6 CHS visits, and it only had a slight effect on making 3–5 CHS visits. Conclusion CHS may play an important role in providing primary health care to meet the demands of vulnerable populations in China. Over time, individuals with higher education are increasingly likely to make frequent CHS visits than individuals with primary school education or below. The gap in frequency of CHS utilization among different economic income groups decreased from 2008 to 2011
A reassuring presence: An evaluation of Bradford District Hospice at Home service
Within the United Kingdom, a developing role for primary care services in cancer and palliative care has resulted in an increase in palliative home care teams. The provision of professional care in the home setting seeks to provide necessary services and enhanced choice for patients whose preference is to die at home.
A mismatch between patient preference for home death and the actual number of people who died at home was identified within Bradford, the locality of this study. In response to this mismatch, and reflecting the policy environment of wishing to enhance community service provision, the four Primary Care Trusts (PCTs) in the city sought to offer support to patients who wished to remain in their own homes through the final stages of a terminal illness. To offer this support they set up a dedicated hospice at home team. This would provide services and support for patients in achieving a dignified, symptom free and peaceful death, allowing families to maximise time spent together. The aim of the study was to evaluate the Bradford hospice at home service from the perspective of carers, nurses and General Practitioners.
Postal questionnaires were sent to carers (n = 289), district nurses (n = 508) and GP's (n = 444) using Bradford's hospice at home service. Resulting quantitative data was analysed using the Statical Package for Social Sciences (SPSS) and qualitative data was analysed using grounded theory techniques.
The data from carers, district nurses and GPs provide general support for the Bradford hospice at home service. Carers valued highly the opportunity to 'fulfil a promise' to the individual who wished to be cared for at home. District nurses and GPs cited the positive impact of access to specialist expertise. This was a 'reassuring presence' for primary healthcare teams and offered 'relief of carer anxiety' by providing prompt, accessible and sensitive care.
Carers and health professionals welcomed the increased possibility of patients being cared for at home. The study identified the need to focus on improving skill levels of staff and on ensuring continuity of care
A massive, quiescent galaxy at redshift of z=3.717
In the early Universe finding massive galaxies that have stopped forming
stars present an observational challenge as their rest-frame ultraviolet
emission is negligible and they can only be reliably identified by extremely
deep near-infrared surveys. These have revealed the presence of massive,
quiescent early-type galaxies appearing in the universe as early as z2,
an epoch 3 Gyr after the Big Bang. Their age and formation processes have now
been explained by an improved generation of galaxy formation models where they
form rapidly at z3-4, consistent with the typical masses and ages derived
from their observations. Deeper surveys have now reported evidence for
populations of massive, quiescent galaxies at even higher redshifts and earlier
times, however the evidence for their existence, and redshift, has relied
entirely on coarsely sampled photometry. These early massive, quiescent
galaxies are not predicted by the latest generation of theoretical models.
Here, we report the spectroscopic confirmation of one of these galaxies at
redshift z=3.717 with a stellar mass of 1.710 M whose
absorption line spectrum shows no current star-formation and which has a
derived age of nearly half the age of the Universe at this redshift. The
observations demonstrates that the galaxy must have quickly formed the majority
of its stars within the first billion years of cosmic history in an extreme and
short starburst. This ancestral event is similar to those starting to be found
by sub-mm wavelength surveys pointing to a possible connection between these
two populations. Early formation of such massive systems is likely to require
significant revisions to our picture of early galaxy assembly.Comment: 6 pages, 7 figures. This is the final preprint corresponding closely
to the published version. Uploaded 6 months after publication in accordance
with Nature polic
Announcing the Minderoo - Monaco Commission on Plastics and Human Health.
© The Author(s), 2022. This article is distributed under the terms of the Creative Commons Attribution License. The definitive version was published in Landrigan, P., Raps, H., Symeonides, C., Chiles, T., Cropper, M., Enck, J., Hahn, M., Hixson, R., Kumar, P., Mustapha, A., Park, Y., Spring, M., Stegeman, J., Thompson, R., Wang, Z., Wolff, M., Yousuf, A., & Dunlop, S. Announcing the Minderoo – Monaco Commission on Plastics and Human Health. Annals of Global Health, 88(1), (2022): 73, https://doi.org/10.5334/aogh.3916.Plastic is the signature material of our age. In the 75 years since large-scale production began in the aftermath of World War II, plastic has transformed our world, supported many of the most significant advances of modern civilization, and enabled breakthroughs in virtually every field of human endeavor. But plastic also poses great and growing dangers to human health and the environment, harms that fall disproportionately on the world’s poorest and most vulnerable populations. The extent and magnitude of these dangers are only beginning to be understood.The funding is from the Minderoo Foundation, the Centre Scientifique de Monaco, and the Prince Albert II of Monaco Foundation
Discovery of a bright quasar without a massive host galaxy
Quasars are thought to be powered by the infall of matter onto a supermassive
black hole at the centre of massive galaxies. As the optical luminosity of
quasars exceeds that of their host galaxy, disentangling the two components can
be difficult. This led in the 1990's to the controversial claim of the
discovery of 'naked' quasars. Since then, the connection between quasars and
galaxies has been well established. Here we report on the observation of a
quasar lying at the edge of a gas cloud, whose size is comparable to that of a
small galaxy, but whose spectrum shows no evidence for stars. The gas cloud is
excited by the quasar itself. If a host galaxy is present, it is at least six
times fainter than would normally be expected for such a bright quasar. The
quasar is interacting dynamically with a neighbouring galaxy - which matter
might be feeding the black hole.Comment: 5 figures, published in Natur
Effect of promoter architecture on the cell-to-cell variability in gene expression
According to recent experimental evidence, the architecture of a promoter,
defined as the number, strength and regulatory role of the operators that
control the promoter, plays a major role in determining the level of
cell-to-cell variability in gene expression. These quantitative experiments
call for a corresponding modeling effort that addresses the question of how
changes in promoter architecture affect noise in gene expression in a
systematic rather than case-by-case fashion. In this article, we make such a
systematic investigation, based on a simple microscopic model of gene
regulation that incorporates stochastic effects. In particular, we show how
operator strength and operator multiplicity affect this variability. We examine
different modes of transcription factor binding to complex promoters
(cooperative, independent, simultaneous) and how each of these affects the
level of variability in transcription product from cell-to-cell. We propose
that direct comparison between in vivo single-cell experiments and theoretical
predictions for the moments of the probability distribution of mRNA number per
cell can discriminate between different kinetic models of gene regulation.Comment: 35 pages, 6 figures, Submitte
Evoked potentials in the Atlantic cod following putatively innocuous and putatively noxious electrical stimulation: a minimally invasive approach
Aspects of peripheral and central nociception
have previously been studied through recording of
somatosensory evoked potentials (SEPs) to putative
noxious stimuli in specific brain regions in a few
freshwater fish species. In the present study, we
describe a novel, minimally invasive method for
recording SEPs from the central nervous system of the
Atlantic cod (Gadus morhua). Cutaneous electric
stimulation of the tail in 15 fish elicited SEPs at all
stimulus intensities (2, 5, 10 and 20 mA) with
quantitative properties corresponding to stimulus
intensity. In contrast to previous fish studies, the
methodological approach used in Atlantic cod in the
current study uncovered a number of additional
responses that could originate from multiple brain
regions. Several of these responses were specific to
stimulation at the highest stimulus intensities, possibly
representing qualitative differences in central processing
between somatosensory and nociceptive stimuli
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Mites Parasitic on Australasian and African Spiders Found in the Pet Trade; a Redescription of Ljunghia pulleinei Womersley
Parasitic mites associated with spiders are spreading world-wide through the trade in tarantulas and other pet species.
Ljunghia pulleinei Womersley, a mesostigmatic laelapid mite originally found in association with the mygalomorph spider
Selenocosmia stirlingi Hogg (Theraphosidae) in Australia, is redescribed and illustrated on the basis of specimens from the
African theraphosid spider Pterinochilus chordatus (Gersta¨cker) kept in captivity in the British Isles (Wales). The mite is known
from older original descriptions of Womersley in 1956; the subsequent redescription of Domrow in 1975 seems to be
questionable in conspecificity of treated specimens with the type material. Some inconsistencies in both descriptions are
recognised here as intraspecific variability of the studied specimens. The genus Arachnyssus Ma, with species A. guangxiensis
(type) and A. huwenae, is not considered to be a valid genus, and is included in synonymy with Ljunghia Oudemans. A new
key to world species of the genus Ljunghia is provided
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