Taming C60 fullerene: Tuning intramolecular photoinduced electron transfer process with subphthalocyanines

Two subphthalocyanine-C60 conjugates have been prepared by means of the 1,3-dipolar cycloaddition reaction of (perfluoro) or hexa(pentylsulfonyl) electron deficient subphthalocyanines to C60. Comprehensive assays regarding the electronic features-in the ground and excited state-of the resulting conjugates revealed energy and electron transfer processes upon photoexcitation. Most important is the unambiguous evidence-in terms of time-resolved spectroscopy-of an ultrafast oxidative electron transfer evolving from C60 to the photoexcited subphthalocyanines. This is, to the best of our knowledge, the first case of an intramolecular oxidation of C60 within electron donor-acceptor conjugates by means of only photoexcitationFinancial support from the MICINN and MEC, Spain (CTQ- 2011-24187/BQU and PRI-PIBUS-2011-1128) is acknowledged. D.M.G. appreciates funding by the DFG (GU 517/14-1) and “Solar Technologies Go Hybrid” – an initiative of the Bavarian State Ministry for Science, Research, and Ar

Synthesis, cytotoxicity, DNA interaction and cell cycle studies of trans-diiodophosphine Pt(ii) complexes

Platinum complexes, bearing aliphatic amines and phosphine ligands in trans configuration with iodide as leaving groups, are synthesized and characterized. The crystal structure of trans-PtI2(isopropylamine)(PPh3) is reported. The complex bearing isopropylamine is demonstrated to be the best candidate as its cytotoxic activity is comparable to or better than cisplatin. A remarkably higher interaction of the complexes with DNA is reported as compared to the parent chlorido series. Cell cycle studies of the complexes in six human cell lines are performed and also compared with the previous seriesThe Spanish Ministerio de Economia y Competitividad has supported this work with the grant: SAF2012-34424. This work was also supported by a School of the Sciences, Stevenson University Seed Gran

Feasible combinatorial matrix theory

We show that the well-known Konig's Min-Max Theorem (KMM), a fundamental result in combinatorial matrix theory, can be proven in the first order theory \LA with induction restricted to $\Sigma_1^B$ formulas. This is an improvement over the standard textbook proof of KMM which requires $\Pi_2^B$ induction, and hence does not yield feasible proofs --- while our new approach does. \LA is a weak theory that essentially captures the ring properties of matrices; however, equipped with $\Sigma_1^B$ induction \LA is capable of proving KMM, and a host of other combinatorial properties such as Menger's, Hall's and Dilworth's Theorems. Therefore, our result formalizes Min-Max type of reasoning within a feasible framework

Intramolecular hydrogen bond activation: Thiourea-organocatalyzed enantioselective 1,3-dipolar cycloaddition of salicylaldehyde-derived azomethine ylides with nitroalkenes

An organocatalytic strategy for the synthesis of tetrasubstituted pyrrolidines with monoactivated azomethine ylides in high enantiomeric excess and excellent exo/endo selectivity is presented. The key to success is the intramolecular activation via hydrogen bonding through an o-hydroxy group, which allows the dipolar cycloaddition to take place in the presence of azomethine ylides bearing only one activating group. The intramolecular hydrogen bond in the azomethine ylide and the intermolecular hydrogen bond with the catalyst have been demonstrated by DFT calculations and mechanistic proofs to be crucial for the reaction to proceedThe Spanish Government (CTQ2015-64561-R, CTQ2016- 76061-P) and the European Research Council (ERC-CG, contract number 647550) are acknowledged. We acknowledge the generous allocation of computing time at the CCC (UAM). S.D.-T. gratefully acknowledges the “Ramón y Cajal” program (RYC-2010-07019). Financial support from the Spanish Ministry of Economy and Competitiveness, through the “Maria de Maeztu” Program of Excellence in R&D (MDM- 2014-0377

Outcomes of Trypanosoma cruzi and Trypanosoma evansi infections on health of Southern coati (Nasua nasua), crab-eating fox (Cerdocyon thous), and ocelot (Leopardus pardalis) in the Brazilian Pantanal.

The occurrence of Trypanosoma spp. in wild carnivore populations has been intensively investigated during the last decades. However, the impact of these parasites on the health of free-living infected animals has been largely neglected. The Pantanal biome is the world's largest seasonal wetland, harboring a great diversity of species and habitats. This includes 174 species of mammals, of which 20 belong to the order Carnivora. The present study aimed to investigate the effect of Trypanosoma evansi and Trypanosoma cruzi infections and coinfections on the health of the most abundant carnivores in the Pantanal: coati (Nasua nasua), crab-eating fox (Cerdocyon thous), and ocelot (Leopardus pardalis). We captured 39 coatis, 48 crab-eating foxes, and 19 ocelots. Diagnostic tests showed T. cruzi infection in 7 crab-eating foxes and 5 coatis. Additionally, 7 crab-eating foxes, 10 coatis, and 12 ocelots were positive for T. evansi. We observed coinfections in 9 crab-eating foxes, 8 coatis, and 2 ocelots. This is the first report of T. evansi and T. cruzi infection on the health of free-living ocelots and crab-eating foxes. We showed that single T. evansi or T. cruzi infection, as well as coinfection, caused some degree of anemia in all animals, as well as an indirect negative effect on body condition in coatis and crab-eating foxes via anemia indicators and immune investment, respectively. Furthermore, the vigorous immune investment observed in sampled coatis, crab-eating foxes and ocelots infected by T. evansi, T. cruzi and coinfected can be highly harmful to their health. Overall, our results indicate that single and combined infection with T. evansi and T. cruzi represent a severe risk to the health of wild carnivores in the Pantanal region

The asymmetric impact of air transport on economic growth in Spain: fresh evidence from the tourism-led growth hypothesis.

The tourism sector has emerged as an essential driver for economic growth strategies during the last decades. An asymmetric long-run effect of air transport on economic growth is validated assuming a process of social globalization in Spain between 1970 and 2015. To achieve the study’s objective, the recent asymmetric autoregressive distributed lag methodology framework advanced by Shin, Yu, and Greenwood-Nimmo (2014) is applied. For determining the causality direction, this methodology is applied in conjunction with the non-parametric causality test proposed by Diks and Panchenko (2006). The current study also accounts for the effects of renewable energy use and urbanization process over economic growth. Empirical results showed that air transport, urbanization process and social globalization exert positive and significant implications over economic growth, while renewable energy use reduces economic growth, as a consequence of an energy mix sustained by fossil sources. Based on these outcomes several policy recommendations were offered in the concluding section

Statement of Foliar Fertilization Impact on Yield, Composition, and Oxidative Biomarkers in Rice

In rice crops, fertilization is a naturalized practice, although inefficient, that could be improved by applying foliar fertilization. Phytoprostanes (PhytoPs) and phytofurans (PhytoFs) are products of α-linolenic acid peroxidation, useful as biomarkers of oxidative degradation in higher plants. The objective was to determine the effect of the foliar fertilization on the concentration of PhytoPs and PhytoFs and its relationships with modifications of yield and quality of rice productions. It was described that the concentration of biomarkers of stress decreased with the application of foliar fertilization, being the response significantly different depending the genotypes and compound monitored. Moreover, fertilization did not modify significantly the parameters of yield (961.2 g m−2), 1000 whole-grain (21.2 g), and protein content (10.7% dry matter). Therefore, this is the first work that describes the effect of fertilization on PhytoPs and PhytoFs in rice genotypes and reinforces the capacity of these compounds as biomarkers to monitor specific abiotic stress, in this case, represented by nutritional stress.Facultad de Ciencias Agrarias y Forestale

Estudio de la correlación confluencia-contagios del Covid-19

In recent years, the main problem to be solved by the whole world has been the Covid-19 pandemic. Most countries have taken measures aimed at reducing mobility as the main tool in the fight against the spread of the virus. This article presents of a case study of the impact of mobility in contagions for the municipality of Málaga, Spain. Preliminary results are presented. Aggregated point of sale purchase registers are used as mobility data within the area of study. The obtained results hint that commercial activity is not the main vector of contagion on the available data on Málaga, although the data volume is insufficient to draw a sharp conclusion.Esta investigación ha sido parcialmente financiada por el Instituto de Salud Carlos III (FONDO–COVID19 para la ejecución de proyectos de investigación SARS-COV-2 y la enfermedad COVID19 en el marco del Real Decreto-ley8/2020) y cofinanciado con fondos FEDER (“Una manera de hacer Europa”) en el marco del Proyecto I+D COV20/00587(Elaboración de cartografías de peligrosidad de transmisión del COVID19 en espacios urbanos orientadas a la aplicación de medidas anti-propagación a escala de detalle). Por otra parte este trabajo ha sido financiado parcialmente por la Universidad a través del I Plan Propio de Investigación y Transferencia de la Universidad de Málaga. Finalmente agradecemos la colaboración de la entidad bancaria Cajamar. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Actas III Congreso Internacional Pobreza y Hambre: Educación y tecnología en el contexto de la pandemia

En el presente volumen publicamos las actas del III Congreso Internacional «Pobreza y Hambre: Educación y Tecnología en el contexto de la pandemia» celebrado en Valencia, durante los días 9 y 10 de noviembre de 2021. En este documento quedan recogidas las intervenciones y ponencias que conformaron el citado congreso, así como las diversas contribuciones, transcripciones, síntesis de mesas de expertos y artículos que dan cuenta de la amplia labor realizada y de la puesta en común que sobre la misma llevaron a cabo los investigadores de la Cátedra de la Caridad de la UCV en el contexto de la pandemia originada por la irrupción del virus SARS/CoV2 en nuestras vidas.Cátedra de la Caridad Santo Tomás de VillanuevaHumanidade