134 research outputs found

    Observation and study of baryonic B decays: B -> D(*) p pbar, D(*) p pbar pi, and D(*) p pbar pi pi

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    We present a study of ten B-meson decays to a D(*), a proton-antiproton pair, and a system of up to two pions using BaBar's data set of 455x10^6 BBbar pairs. Four of the modes (B0bar -> D0 p anti-p, B0bar -> D*0 p anti-p, B0bar -> D+ p anti-p pi-, B0bar -> D*+ p anti-p pi-) are studied with improved statistics compared to previous measurements; six of the modes (B- -> D0 p anti-p pi-, B- -> D*0 p anti-p pi-, B0bar -> D0 p anti-p pi- pi+, B0bar -> D*0 p anti-p pi- pi+, B- -> D+ p anti-p pi- pi-, B- -> D*+ p anti-p pi- pi-) are first observations. The branching fractions for 3- and 5-body decays are suppressed compared to 4-body decays. Kinematic distributions for 3-body decays show non-overlapping threshold enhancements in m(p anti-p) and m(D(*)0 p) in the Dalitz plots. For 4-body decays, m(p pi-) mass projections show a narrow peak with mass and full width of (1497.4 +- 3.0 +- 0.9) MeV/c2, and (47 +- 12 +- 4) MeV/c2, respectively, where the first (second) errors are statistical (systematic). For 5-body decays, mass projections are similar to phase space expectations. All results are preliminary.Comment: 28 pages, 90 postscript figures, submitted to LP0

    Search for the highly suppressed decays B- -> K+π-π- and B- -> K-K-π+

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    We report a search for the decays B- -> K+pi(-)pi(-) and B- -> K-K-pi(+), which are highly suppressed in the standard model. Using a sample of (467 +/- 5) x 10(6) B (B) over bar pairs collected with the BABAR detector, we do not see any evidence of these decays and determine 90% confidence level upper limits of B(B- -> K+pi(-)pi(-)) and K-K-pi(+)) and < 1.6 x 10(-7) on the corresponding branching fractions, including systematic uncertainties

    Representações de profissionais de saúde sobre a morte e o processo de morrer

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    Os currículos da área de saúde deixam uma lacuna na formação teórica e prática, permitindo que a morte seja interpretada como fracasso. A pesquisa objetivou apreender as representações sociais da morte e do processo de morrer para os profissionais de saúde. Trata-se de uma pesquisa qualitativa de natureza exploratória. Foram entrevistados cinco profissionais de saúde que prestam assistência a pacientes fora de possibilidades de cura. Utilizou-se o software Alceste para apreender o conteúdo das representações sociais dos entrevistados. Da análise de conteúdo das entrevistas emergiram dois eixos distintos: o primeiro eixo agrupa classes que dizem respeito à dimensão do profissional frente à morte; o segundo eixo refere-se à dimensão subjetiva frente à morte. Os resultados ressaltam a necessidade de investir na capacitação dos alunos não somente no desenvolvimento de habilidades técnicas, mas também no desenvolvimento de habilidades interpessoais, elementos fundamentais para o cuidado humano, sobretudo diante a morte

    Transforming growth factor-&#946;1 in congenital ureteropelvic junction obstruction: diagnosis and follow-up

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    OBJECTIVE: To assess the role of transforming growth factor-&#946;1 (TGF-&#946;1) in congenital ureteropelvic junction obstruction at diagnosis and during postoperative follow-up. MATERIAL AND METHODS: We conducted a case-control study including 19 patients with a mean age of 6.7 years and 19 matched controls. All patients presented negative voiding cystourethrography, obstructive diuretic renogram and underwent dismembered pyeloplasty. Urinary TGF-&#946;1 and other markers were measured pre-, intra- and postoperatively. RESULTS: The mean bladder urine TGF-&#946;1 concentration in obstructed patients prior to pyeloplasty was higher than in controls (92.5 pg/mL ± 16.8 vs. 35.8 pg/mL ± 16.2; p = 0.0001). The mean renal pelvic urine TGF-&#946;1 concentration in the hydronephrotic kidney was higher than in the preoperative bladder urine sample (122.3 pg/mL ± 43.9 vs. 92.5 pg/mL ± 16.8; p = 0.036). Postoperative mean TGF-&#946;1 concentration was significantly lower than preoperative TGF-&#946;1 (48.7 pg/mL ± 13.1 vs. 92.5 pg/mL ± 16.8; p = 0.0001). CONCLUSION: TGF-&#946;1 is a cytokine leading to renal fibrosis. The measurement of urinary TGF-&#946;1 could become a useful tool for the diagnosis of obstructive hydronephrosis and the evaluation of the parenchyma function status, pre and postoperatively

    Optimizing the AKI definition during first postnatal week using Assessment of Worldwide Acute Kidney Injury Epidemiology in Neonates (AWAKEN) cohort.

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    BACKGROUND: Neonates with serum creatinine (SCr) rise ≥0.3 mg/dL and/or ≥50% SCr rise are more likely to die, even when controlling for confounders. These thresholds have not been tested in newborns. We hypothesized that different gestational age (GA) groups require different SCr thresholds. METHODS: Neonates in Assessment of Worldwide Acute Kidney Epidemiology in Neonates (AWAKEN) with ≥1 SCr on postnatal days 1-2 and ≥1 SCr on postnatal days 3-8 were assessed. We compared the mortality predictability of SCr absolute (≥0.3 mg/dL) vs percent (≥50%) rise. Next, we determine usefulness of combining absolute with percent rise. Finally, we determined the optimal absolute, percent, and maximum SCr thresholds that provide the highest mortality area under curve (AUC) and specificity for different GA groups. RESULTS: The ≥0.3 mg/dL rise outperformed ≥50% SCr rise. Addition of percent rise did not improve mortality predictability. The optimal SCr thresholds to predict AUC and specificity were ≥0.3 and ≥0.6 mg/dL for ≤29 weeks GA, and ≥0.1 and ≥0.3 mg/dL for \u3e29 week GA. The maximum SCr value provides great specificity. CONCLUSION: Unique SCr rise cutoffs for different GA improves outcome prediction. Percent SCr rise does not add value to the neonatal AKI definition
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