Effect of Axial Agitator Configuration (Up-Pumping, Down-Pumping, Reverse Rotation) on Flow Patterns Generated in Stirred Vessels

Single phase turbulent flow in a tank stirred with two different axial impellers - a pitched blade turbine (PBT) and a Mixel TT (MTT)- has been studied using Laser Doppler Velocimetry. The effect of the agitator configuration, i.e. up-pumping, down-pumping and reverse rotation, on the turbulent flow field, as well as power, circulation and pumping numbers has been investigated. An agitation index for each configuration was also determined. In the down-pumping mode, the impellers induced one circulation loop and the upper part of the tank was poorly mixed. When up-pumping, two circulation loops are formed, the second in the upper vessel. The PBT pumping upwards was observed to have a lower flow number and to consume more power than when down-pumping, however the agitation index and circulation efficiencies were notably higher. The MTT has been shown to circulate liquid more efficiently in the up-pumping configuration than in the other two modes. Only small effects of the MTT configuration on the power number, flow number and pumping effectiveness have been observed

Testing hypotheses of the cause of peripheral thinning of the Greenland Ice Sheet: is land-terminating ice thinning at anomalously high rates?

Recent observations have shown that the periphery of the Greenland ice sheet (GrIS) is thinning rapidly and that this thinning is greatest around marine-terminating outlet glaciers. Several theories have been proposed which provide a link between climate and ice thinning. We present surface elevation change (<i>dh/dt</i>) data from NASA's Program for Arctic Regional Climate Assessment (PARCA) laser altimetry surveys for fourteen and eleven of the largest outlet glaciers in Southern Greenland from 1993 to 1998 and 1998 to 2006 respectively to test the applicability of these theories to the GrIS. <br><br> Initially, outlet glacier <i>dh/dt</i> data are compared with data from concurrent surveys over inland ice (slow flowing ice that is not obviously draining into an outlet glacier) to confirm the effect of ice flow on surface thinning rates. Land-terminating and marine-terminating outlet glacier <i>dh/dt</i> data are then compared from 1993 to 1998 and from 1998 to 2006. Finally, ablation anomalies (the difference between the "normal" ablation rate from 1970 to 2000 and the ablation rate in the time period of interest) calculated with a positive degree day model are compared to both marine-terminating and land-terminating outlet glacier <i>dh/dt</i> data. <br><br> Our results support earlier conclusions that certain marine-terminating outlet glaciers have thinned much more than land-terminating outlet glaciers during both time periods. Furthermore we show that these differences are not limited to the largest, fastest-flowing outlet glaciers – almost all marine-terminating outlet glaciers are thinning more than land-terminating outlet glaciers. There was a four fold increase in mean marine-terminating outlet glacier thinning rates below 1000 m elevation between the periods 1993 to 1998 and 1998 to 2006, while thinning rates of land-terminating outlet glaciers remained statistically unchanged. This suggests that a change in a controlling mechanism specific to the thinning rates of marine-terminating outlet glaciers occurred in the late 1990s and that this change did not affect thinning rates of land-terminating outlet glaciers. <br><br> Thinning rates of land-terminating outlet glaciers are statistically the same as ablation anomalies, while thinning rates of marine-terminating outlet glaciers are not. Thinning of land-terminating outlet glaciers therefore seems to be a response to changes in local mass balance (principally increases in air temperature) while thinning of marine-terminating outlet glaciers is principally controlled by ice dynamics. The mechanism by which this dynamic thinning occurs is still not clear although its association with marine-terminating outlet glaciers suggests perturbations at marine termini (calving) as the likely cause

Agitation conditions for the culture and detachment of hMSCs from microcarriers in multiple bioreactor platforms

In our recent work in different bioreactors up to 2.5L in scale, we have successfully cultured hMSCs using the minimum agitator speed required for complete microcarrier suspension, N JS. In addition, we also reported a scaleable protocol for the detachment from microcarriers in spinner flasks of hMSCs from two donors. The essence of the protocol is the use of a short period of intense agitation in the presence of enzymes such that the cells are detached; but once detachment is achieved, the cells are smaller than the Kolmogorov scale of turbulence and hence not damaged. Here, the same approach has been effective for culture at N JS and detachment in-situ in 15mL ambr™ bioreactors, 100mL spinner flasks and 250mL Dasgip bioreactors. In these experiments, cells from four different donors were used along with two types of microcarrier with and without surface coatings (two types), four different enzymes and three different growth media (with and without serum), a total of 22 different combinations. In all cases after detachment, the cells were shown to retain their desired quality attributes and were able to proliferate. This agitation strategy with respect to culture and harvest therefore offers a sound basis for a wide range of scales of operation

Seasonal variations in Greenland Ice Sheet motion : Inland extent and behaviour at higher elevations

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Field-calibrated model of melt, refreezing, and runoff for polar ice caps : Application to Devon Ice Cap

Acknowledgments R.M.M. was supported by the Scottish Alliance for Geoscience, Environment and Society (SAGES). The field data collection contributed to the validation of the European Space Agency Cryosat mission and was supported by the Natural Sciences and Engineering Research Council, Canada, the Meteorological Service of Canada (CRYSYS program), the Polar Continental Shelf Project (an agency of Natural Resources Canada), and by UK Natural Environment Research Council consortium grant NER/O/S/2003/00620. Support for D.O.B. was provided by the Canadian Circumpolar Institute and the Climate Change Geoscience Program, Earth Sciences Sector, Natural Resources Canada (ESS contribution 20130371). Thanks are also due to the Nunavut Research Institute and the communities of Resolute Bay and Grise Fjord for permission to conduct fieldwork on Devon Ice Cap. M.J. Sharp, A. Gardner, F. Cawkwell, R. Bingham, S. Williamson, L. Colgan, J. Davis, B. Danielson, J. Sekerka, L. Gray, and J. Zheng are thanked for logistical support and field assistance during the data collection. We thank Ruzica Dadic, two other anonymous reviewers, and the Editor, Bryn Hubbard, for their helpful comments on an earlier version of this paper and which resulted in significant improvements.Peer reviewedPublisher PD

Linear response of east Greenland's tidewater glaciers to ocean/atmosphere warming.

Predicting the retreat of tidewater outlet glaciers forms a major obstacle to forecasting the rate of mass loss from the Greenland Ice Sheet. This reflects the challenges of modeling the highly dynamic, topographically complex, and data-poor environment of the glacier-fjord systems that link the ice sheet to the ocean. To avoid these difficulties, we investigate the extent to which tidewater glacier retreat can be explained by simple variables: air temperature, meltwater runoff, ocean temperature, and two simple parameterizations of "ocean/atmosphere" forcing based on the combined influence of runoff and ocean temperature. Over a 20-y period at 10 large tidewater outlet glaciers along the east coast of Greenland, we find that ocean/atmosphere forcing can explain up to 76% of the variability in terminus position at individual glaciers and 54% of variation in terminus position across all 10 glaciers. Our findings indicate that (i) the retreat of east Greenland's tidewater glaciers is best explained as a product of both oceanic and atmospheric warming and (ii) despite the complexity of tidewater glacier behavior, over multiyear timescales a significant proportion of terminus position change can be explained as a simple function of this forcing. These findings thus demonstrate that simple parameterizations can play an important role in predicting the response of the ice sheet to future climate warming

Fluctuations of a Greenlandic tidewater glacier driven by changes in atmospheric forcing : observations and modelling of Kangiata Nunaata Sermia, 1859–present

Acknowledgements. The authors wish to thank Stephen Price, Mauri Pelto, and the anonymous reviewer for their reviews and comments that helped to improve the manuscript. RACMO2.1 data were provided by Jan van Angelen and Michiel van den Broeke, IMAU, Utrecht University. MAR v3.2 data used for runoff calculations were provided by Xavier Fettweis, Department of Geography, University of Liège. The photogrammetric DEM used in Figs. 1 and 3 was provided by Kurt H. Kjær, Centre for GeoGenetics, University of Copenhagen. This research was financially supported by J. M. Lea’s PhD funding, NERC grant number NE/I528742/1. Support for F. M. Nick was provided through the Conoco-Phillips/Lundin Northern Area Program CRIOS project (Calving Rates and Impact on Sea Level).Peer reviewedPublisher PD